U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Arthritis, sacroiliac

MedGen UID:
148186
Concept ID:
C0748473
Disease or Syndrome
Synonyms: Arthritis, Sacroiliac; Sacroiliac arthritis
 
HPO: HP:0012317
Monarch Initiative: MONDO:0007156
OMIM®: 108100

Definition

Inflammation of the sacroiliac joint, generally accompanied by lower back pain. [from HPO]

Conditions with this feature

Spondyloarthropathy, susceptibility to, 1
MedGen UID:
400145
Concept ID:
C1862852
Finding
Spondyloarthropathy (SpA), one of the commonest chronic rheumatic diseases, includes a spectrum of related disorders comprising the prototype ankylosing spondylitis (AS), a subset of psoriatic arthritis (PsA), reactive arthritis (ReA), arthritis associated with inflammatory bowel disease, and undifferentiated spondyloarthropathy (Miceli-Richard et al., 2004). These phenotypes are difficult to differentiate because they may occur simultaneously or sequentially in the same patient. Studies have suggested that a predominant shared component, including HLA-B27, predisposes to all phenotypic subsets, and that these subsets should be considered as various phenotypic expressions of the same disease (Said-Nahal et al., 2000, Said-Nahal et al., 2001). Braun and Sieper (2007) provided a detailed review of ankylosing spondylitis, including clinical features, pathogenesis, and management. Genetic Heterogeneity of Susceptibility to Spondyloarthropathy Additional susceptibility loci for spondyloarthropathy have been identified on chromosome 9q31-q34 (SPDA2; 183840) and chromosome 2q36 (SPDA3; 613238).

Professional guidelines

PubMed

Savran Sahin B, Aktas E, Haberal B, Harman A, Canan Yazici A, Kaygusuz H, Aribas BK
Eur Rev Med Pharmacol Sci 2015 Aug;19(15):2804-11. PMID: 26241533

Recent clinical studies

Etiology

Liu WX, Wu H, Cai C, Lai QQ, Wang Y, Li YZ
J Orthop Surg Res 2024 Jan 30;19(1):96. doi: 10.1186/s13018-024-04569-3. PMID: 38287422Free PMC Article
Aitken-Saavedra J, Maturana-Ramirez A, Fernández Moraga J, Doro Dias V, Galdino-Santos L, Pineda Flores D
Dermatol Online J 2021 Jul 15;27(7) doi: 10.5070/D327754373. PMID: 34391335
Cohen SP, Bicket MC, Kurihara C, Griffith SR, Fowler IM, Jacobs MB, Liu R, Anderson White M, Verdun AJ, Hari SB, Fisher RL, Pasquina PF, Vorobeychik Y
Mayo Clin Proc 2019 Apr;94(4):628-642. Epub 2019 Mar 8 doi: 10.1016/j.mayocp.2018.08.038. PMID: 30853260
de Koning A, Schoones JW, van der Heijde D, van Gaalen FA
Eur J Clin Invest 2018 May;48(5):e12913. Epub 2018 Mar 13 doi: 10.1111/eci.12913. PMID: 29460306
Savran Sahin B, Aktas E, Haberal B, Harman A, Canan Yazici A, Kaygusuz H, Aribas BK
Eur Rev Med Pharmacol Sci 2015 Aug;19(15):2804-11. PMID: 26241533

Diagnosis

Aitken-Saavedra J, Maturana-Ramirez A, Fernández Moraga J, Doro Dias V, Galdino-Santos L, Pineda Flores D
Dermatol Online J 2021 Jul 15;27(7) doi: 10.5070/D327754373. PMID: 34391335
de Koning A, Schoones JW, van der Heijde D, van Gaalen FA
Eur J Clin Invest 2018 May;48(5):e12913. Epub 2018 Mar 13 doi: 10.1111/eci.12913. PMID: 29460306
D'Agostino MA, Terslev L
Rheum Dis Clin North Am 2016 Nov;42(4):679-693. Epub 2016 Sep 7 doi: 10.1016/j.rdc.2016.07.012. PMID: 27742021
Maksymowych WP
Rheum Dis Clin North Am 2016 Nov;42(4):645-662. Epub 2016 Sep 6 doi: 10.1016/j.rdc.2016.07.003. PMID: 27742019
Liegeois C, Stewart C
BMJ Case Rep 2015 Aug 14;2015 doi: 10.1136/bcr-2014-208469. PMID: 26276848Free PMC Article

Therapy

Liu WX, Wu H, Cai C, Lai QQ, Wang Y, Li YZ
J Orthop Surg Res 2024 Jan 30;19(1):96. doi: 10.1186/s13018-024-04569-3. PMID: 38287422Free PMC Article
Cohen SP, Bicket MC, Kurihara C, Griffith SR, Fowler IM, Jacobs MB, Liu R, Anderson White M, Verdun AJ, Hari SB, Fisher RL, Pasquina PF, Vorobeychik Y
Mayo Clin Proc 2019 Apr;94(4):628-642. Epub 2019 Mar 8 doi: 10.1016/j.mayocp.2018.08.038. PMID: 30853260
Gago R, Vilá S, Vélez-Rivera J, Vilá LM
BMJ Case Rep 2018 Jan 24;2018 doi: 10.1136/bcr-2017-222474. PMID: 29367221Free PMC Article
Jee H, Lee JH, Park KD, Ahn J, Park Y
Arch Phys Med Rehabil 2014 Feb;95(2):330-7. Epub 2013 Oct 9 doi: 10.1016/j.apmr.2013.09.021. PMID: 24121083

Prognosis

Savran Sahin B, Aktas E, Haberal B, Harman A, Canan Yazici A, Kaygusuz H, Aribas BK
Eur Rev Med Pharmacol Sci 2015 Aug;19(15):2804-11. PMID: 26241533

Clinical prediction guides

Aitken-Saavedra J, Maturana-Ramirez A, Fernández Moraga J, Doro Dias V, Galdino-Santos L, Pineda Flores D
Dermatol Online J 2021 Jul 15;27(7) doi: 10.5070/D327754373. PMID: 34391335
Cohen SP, Bicket MC, Kurihara C, Griffith SR, Fowler IM, Jacobs MB, Liu R, Anderson White M, Verdun AJ, Hari SB, Fisher RL, Pasquina PF, Vorobeychik Y
Mayo Clin Proc 2019 Apr;94(4):628-642. Epub 2019 Mar 8 doi: 10.1016/j.mayocp.2018.08.038. PMID: 30853260
Jadon DR, Sengupta R, Nightingale A, Lindsay M, Korendowych E, Robinson G, Jobling A, Shaddick G, Bi J, Winchester R, Giles JT, McHugh NJ
Ann Rheum Dis 2017 Apr;76(4):701-707. Epub 2016 Dec 2 doi: 10.1136/annrheumdis-2016-209853. PMID: 27913376Free PMC Article
Baraliakos X, Braun J
Rheum Dis Clin North Am 2016 Nov;42(4):663-678. doi: 10.1016/j.rdc.2016.07.006. PMID: 27742020
Savran Sahin B, Aktas E, Haberal B, Harman A, Canan Yazici A, Kaygusuz H, Aribas BK
Eur Rev Med Pharmacol Sci 2015 Aug;19(15):2804-11. PMID: 26241533

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...