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Arthritis, sacroiliac

MedGen UID:
148186
Concept ID:
C0748473
Disease or Syndrome
Synonyms: Arthritis, Sacroiliac; Sacroiliac arthritis
 
HPO: HP:0012317
Monarch Initiative: MONDO:0007156
OMIM®: 108100

Definition

Inflammation of the sacroiliac joint, generally accompanied by lower back pain. [from HPO]

Conditions with this feature

Spondyloarthropathy, susceptibility to, 1
MedGen UID:
400145
Concept ID:
C1862852
Finding
Spondyloarthropathy (SpA), one of the commonest chronic rheumatic diseases, includes a spectrum of related disorders comprising the prototype ankylosing spondylitis (AS), a subset of psoriatic arthritis (PsA), reactive arthritis (ReA), arthritis associated with inflammatory bowel disease, and undifferentiated spondyloarthropathy (Miceli-Richard et al., 2004). These phenotypes are difficult to differentiate because they may occur simultaneously or sequentially in the same patient. Studies have suggested that a predominant shared component, including HLA-B27, predisposes to all phenotypic subsets, and that these subsets should be considered as various phenotypic expressions of the same disease (Said-Nahal et al., 2000, Said-Nahal et al., 2001). Braun and Sieper (2007) provided a detailed review of ankylosing spondylitis, including clinical features, pathogenesis, and management. Genetic Heterogeneity of Susceptibility to Spondyloarthropathy Additional susceptibility loci for spondyloarthropathy have been identified on chromosome 9q31-q34 (SPDA2; 183840) and chromosome 2q36 (SPDA3; 613238).

Professional guidelines

PubMed

Savran Sahin B, Aktas E, Haberal B, Harman A, Canan Yazici A, Kaygusuz H, Aribas BK
Eur Rev Med Pharmacol Sci 2015 Aug;19(15):2804-11. PMID: 26241533

Recent clinical studies

Etiology

Liu WX, Wu H, Cai C, Lai QQ, Wang Y, Li YZ
J Orthop Surg Res 2024 Jan 30;19(1):96. doi: 10.1186/s13018-024-04569-3. PMID: 38287422Free PMC Article
Aitken-Saavedra J, Maturana-Ramirez A, Fernández Moraga J, Doro Dias V, Galdino-Santos L, Pineda Flores D
Dermatol Online J 2021 Jul 15;27(7) doi: 10.5070/D327754373. PMID: 34391335
Cohen SP, Bicket MC, Kurihara C, Griffith SR, Fowler IM, Jacobs MB, Liu R, Anderson White M, Verdun AJ, Hari SB, Fisher RL, Pasquina PF, Vorobeychik Y
Mayo Clin Proc 2019 Apr;94(4):628-642. Epub 2019 Mar 8 doi: 10.1016/j.mayocp.2018.08.038. PMID: 30853260
de Koning A, Schoones JW, van der Heijde D, van Gaalen FA
Eur J Clin Invest 2018 May;48(5):e12913. Epub 2018 Mar 13 doi: 10.1111/eci.12913. PMID: 29460306
Savran Sahin B, Aktas E, Haberal B, Harman A, Canan Yazici A, Kaygusuz H, Aribas BK
Eur Rev Med Pharmacol Sci 2015 Aug;19(15):2804-11. PMID: 26241533

Diagnosis

Liu WX, Wu H, Cai C, Lai QQ, Wang Y, Li YZ
J Orthop Surg Res 2024 Jan 30;19(1):96. doi: 10.1186/s13018-024-04569-3. PMID: 38287422Free PMC Article
Aitken-Saavedra J, Maturana-Ramirez A, Fernández Moraga J, Doro Dias V, Galdino-Santos L, Pineda Flores D
Dermatol Online J 2021 Jul 15;27(7) doi: 10.5070/D327754373. PMID: 34391335
de Koning A, Schoones JW, van der Heijde D, van Gaalen FA
Eur J Clin Invest 2018 May;48(5):e12913. Epub 2018 Mar 13 doi: 10.1111/eci.12913. PMID: 29460306
D'Agostino MA, Terslev L
Rheum Dis Clin North Am 2016 Nov;42(4):679-693. Epub 2016 Sep 7 doi: 10.1016/j.rdc.2016.07.012. PMID: 27742021
Maksymowych WP
Rheum Dis Clin North Am 2016 Nov;42(4):645-662. Epub 2016 Sep 6 doi: 10.1016/j.rdc.2016.07.003. PMID: 27742019

Therapy

Liu WX, Wu H, Cai C, Lai QQ, Wang Y, Li YZ
J Orthop Surg Res 2024 Jan 30;19(1):96. doi: 10.1186/s13018-024-04569-3. PMID: 38287422Free PMC Article
Cohen SP, Bicket MC, Kurihara C, Griffith SR, Fowler IM, Jacobs MB, Liu R, Anderson White M, Verdun AJ, Hari SB, Fisher RL, Pasquina PF, Vorobeychik Y
Mayo Clin Proc 2019 Apr;94(4):628-642. Epub 2019 Mar 8 doi: 10.1016/j.mayocp.2018.08.038. PMID: 30853260
Gago R, Vilá S, Vélez-Rivera J, Vilá LM
BMJ Case Rep 2018 Jan 24;2018 doi: 10.1136/bcr-2017-222474. PMID: 29367221Free PMC Article
Jee H, Lee JH, Park KD, Ahn J, Park Y
Arch Phys Med Rehabil 2014 Feb;95(2):330-7. Epub 2013 Oct 9 doi: 10.1016/j.apmr.2013.09.021. PMID: 24121083

Prognosis

Savran Sahin B, Aktas E, Haberal B, Harman A, Canan Yazici A, Kaygusuz H, Aribas BK
Eur Rev Med Pharmacol Sci 2015 Aug;19(15):2804-11. PMID: 26241533

Clinical prediction guides

Aitken-Saavedra J, Maturana-Ramirez A, Fernández Moraga J, Doro Dias V, Galdino-Santos L, Pineda Flores D
Dermatol Online J 2021 Jul 15;27(7) doi: 10.5070/D327754373. PMID: 34391335
Cohen SP, Bicket MC, Kurihara C, Griffith SR, Fowler IM, Jacobs MB, Liu R, Anderson White M, Verdun AJ, Hari SB, Fisher RL, Pasquina PF, Vorobeychik Y
Mayo Clin Proc 2019 Apr;94(4):628-642. Epub 2019 Mar 8 doi: 10.1016/j.mayocp.2018.08.038. PMID: 30853260
Jadon DR, Sengupta R, Nightingale A, Lindsay M, Korendowych E, Robinson G, Jobling A, Shaddick G, Bi J, Winchester R, Giles JT, McHugh NJ
Ann Rheum Dis 2017 Apr;76(4):701-707. Epub 2016 Dec 2 doi: 10.1136/annrheumdis-2016-209853. PMID: 27913376Free PMC Article
Baraliakos X, Braun J
Rheum Dis Clin North Am 2016 Nov;42(4):663-678. doi: 10.1016/j.rdc.2016.07.006. PMID: 27742020
Savran Sahin B, Aktas E, Haberal B, Harman A, Canan Yazici A, Kaygusuz H, Aribas BK
Eur Rev Med Pharmacol Sci 2015 Aug;19(15):2804-11. PMID: 26241533

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