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Desmoplastic/nodular medulloblastoma

MedGen UID:
148272
Concept ID:
C0751291
Neoplastic Process
Synonyms: Medulloblastoma, desmoplastic; Medulloblastoma, desmoplastic, somatic
SNOMED CT: Desmoplastic nodular medulloblastoma (32456001); Desmoplastic medulloblastoma (32456001); Circumscribed arachnoidal cerebellar sarcoma (32456001)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0016711
Orphanet: ORPHA251863

Definition

Medulloblastoma with extensive nodularity and advanced neuronal differentiation. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDesmoplastic/nodular medulloblastoma
Follow this link to review classifications for Desmoplastic/nodular medulloblastoma in Orphanet.

Professional guidelines

PubMed

Naung H, Cohen KJ
J Neurooncol 2021 May;152(3):567-572. Epub 2021 Mar 10 doi: 10.1007/s11060-021-03727-5. PMID: 33689104
Bhimani AD, Ryoo JS, Reddy AK, Denyer S, McGuire LS, Alonso M, Mehta AI
World Neurosurg 2020 Sep;141:e289-e306. Epub 2020 May 17 doi: 10.1016/j.wneu.2020.05.103. PMID: 32434022
AbdelBaki MS, Boué DR, Finlay JL, Kieran MW
Neuro Oncol 2018 Jul 5;20(8):1026-1033. doi: 10.1093/neuonc/nox222. PMID: 29156007Free PMC Article

Recent clinical studies

Etiology

Cassia GSE, Alves CAPF, Taranath A, López NS, Oztekin O, Gonçalves FG, Patay Z
Top Magn Reson Imaging 2018 Dec;27(6):479-502. doi: 10.1097/RMR.0000000000000184. PMID: 30516696
AbdelBaki MS, Boué DR, Finlay JL, Kieran MW
Neuro Oncol 2018 Jul 5;20(8):1026-1033. doi: 10.1093/neuonc/nox222. PMID: 29156007Free PMC Article
Aristizabal P, Burns L, Rivera-Gomez R, Levy ML, Roberts W, Crawford JR
J Pediatr Hematol Oncol 2017 May;39(4):299-301. doi: 10.1097/MPH.0000000000000798. PMID: 28267079
Mangum R, Varga E, Boué DR, Capper D, Benesch M, Leonard J, Osorio DS, Pierson CR, Zumberge N, Sahm F, Schrimpf D, Pfister SM, Finlay JL
Childs Nerv Syst 2016 Dec;32(12):2439-2446. Epub 2016 Jul 21 doi: 10.1007/s00381-016-3185-0. PMID: 27444290
Siegfried A, Bertozzi AI, Bourdeaut F, Sevely A, Loukh N, Grison C, Miquel C, Lafon D, Sevenet N, Pietsch T, Dufour C, Delisle MB
Clin Neuropathol 2016 May-Jun;35(3):106-13. doi: 10.5414/NP300205. PMID: 26857864Free PMC Article

Diagnosis

Cassia GSE, Alves CAPF, Taranath A, López NS, Oztekin O, Gonçalves FG, Patay Z
Top Magn Reson Imaging 2018 Dec;27(6):479-502. doi: 10.1097/RMR.0000000000000184. PMID: 30516696
Aristizabal P, Burns L, Rivera-Gomez R, Levy ML, Roberts W, Crawford JR
J Pediatr Hematol Oncol 2017 May;39(4):299-301. doi: 10.1097/MPH.0000000000000798. PMID: 28267079
Kalogeraki A, Tamiolakis D, Mavrigiannaki P, Karvelaskalogerakis M, Datseri G, Agelaki S, Papadopoulos S
Rom J Intern Med 2016 Apr-Jun;54(2):137-9. doi: 10.1515/rjim-2016-0018. PMID: 27352444
Siegfried A, Bertozzi AI, Bourdeaut F, Sevely A, Loukh N, Grison C, Miquel C, Lafon D, Sevenet N, Pietsch T, Dufour C, Delisle MB
Clin Neuropathol 2016 May-Jun;35(3):106-13. doi: 10.5414/NP300205. PMID: 26857864Free PMC Article
Yamasaki F, Takayasu T, Nosaka R, Kawaguchi H, Sugiyama K, Kobayashi M, Kurisu K
Childs Nerv Syst 2016 Feb;32(2):395-8. Epub 2015 Aug 1 doi: 10.1007/s00381-015-2848-6. PMID: 26231569

Therapy

AbdelBaki MS, Boué DR, Finlay JL, Kieran MW
Neuro Oncol 2018 Jul 5;20(8):1026-1033. doi: 10.1093/neuonc/nox222. PMID: 29156007Free PMC Article
Aristizabal P, Burns L, Rivera-Gomez R, Levy ML, Roberts W, Crawford JR
J Pediatr Hematol Oncol 2017 May;39(4):299-301. doi: 10.1097/MPH.0000000000000798. PMID: 28267079
Yamasaki F, Takayasu T, Nosaka R, Kawaguchi H, Sugiyama K, Kobayashi M, Kurisu K
Childs Nerv Syst 2016 Feb;32(2):395-8. Epub 2015 Aug 1 doi: 10.1007/s00381-015-2848-6. PMID: 26231569
Zhang ZY, Xu J, Ren Y, Li KK, Ng HK, Mao Y, Zhong P, Yao Y, Zhou LF
PLoS One 2014;9(6):e99490. Epub 2014 Jun 16 doi: 10.1371/journal.pone.0099490. PMID: 24932704Free PMC Article
Grundy RG, Wilne SH, Robinson KJ, Ironside JW, Cox T, Chong WK, Michalski A, Campbell RH, Bailey CC, Thorp N, Pizer B, Punt J, Walker DA, Ellison DW, Machin D; Children's Cancer and Leukaemia Group (formerly UKCCSG) Brain Tumour Committee
Eur J Cancer 2010 Jan;46(1):120-33. doi: 10.1016/j.ejca.2009.09.013. PMID: 19818598

Prognosis

Tonn S, Korshunov A, Obrecht D, Sill M, Spohn M, von Hoff K, Milde T, Pietsch T, Goschzik T, Bison B, Juhnke BO, Struve N, Sturm D, Sahm F, Bockmayr M, Friedrich C, von Bueren AO, Gerber NU, Benesch M, Jones DTW, Kool M, Wefers AK, Schüller U, Pfister SM, Rutkowski S, Mynarek M
Neuro Oncol 2023 Aug 3;25(8):1518-1529. doi: 10.1093/neuonc/noad027. PMID: 36715306Free PMC Article
AbdelBaki MS, Boué DR, Finlay JL, Kieran MW
Neuro Oncol 2018 Jul 5;20(8):1026-1033. doi: 10.1093/neuonc/nox222. PMID: 29156007Free PMC Article
Kalogeraki A, Tamiolakis D, Mavrigiannaki P, Karvelaskalogerakis M, Datseri G, Agelaki S, Papadopoulos S
Rom J Intern Med 2016 Apr-Jun;54(2):137-9. doi: 10.1515/rjim-2016-0018. PMID: 27352444
Ryzhova MV, Zheludkova OG, Kumirova ÉV, Shishkina LV, Panina TN, Gorelyshev SK, Khukhlaeva EA, Mazerkina NA, Matuev KB, Medvedeva OA, Tarasova EM, Kholodov BV, Kapitul'skaia OIu
Zh Vopr Neirokhir Im N N Burdenko 2013;77(1):3-10; discussion 11. PMID: 23659115
Verma S, Tavaré CJ, Gilles FH
Pediatr Dev Pathol 2008 Sep-Oct;11(5):337-43. Epub 2008 Jan 17 doi: 10.2350/07-09-0353.1. PMID: 18201118

Clinical prediction guides

Tonn S, Korshunov A, Obrecht D, Sill M, Spohn M, von Hoff K, Milde T, Pietsch T, Goschzik T, Bison B, Juhnke BO, Struve N, Sturm D, Sahm F, Bockmayr M, Friedrich C, von Bueren AO, Gerber NU, Benesch M, Jones DTW, Kool M, Wefers AK, Schüller U, Pfister SM, Rutkowski S, Mynarek M
Neuro Oncol 2023 Aug 3;25(8):1518-1529. doi: 10.1093/neuonc/noad027. PMID: 36715306Free PMC Article
Korostyshevskaya AM, Savelov AA, Papusha LI, Druy AE, Yarnykh VL
Clin Imaging 2018 Nov-Dec;52:172-176. Epub 2018 Jun 7 doi: 10.1016/j.clinimag.2018.06.001. PMID: 30096555
Mangum R, Varga E, Boué DR, Capper D, Benesch M, Leonard J, Osorio DS, Pierson CR, Zumberge N, Sahm F, Schrimpf D, Pfister SM, Finlay JL
Childs Nerv Syst 2016 Dec;32(12):2439-2446. Epub 2016 Jul 21 doi: 10.1007/s00381-016-3185-0. PMID: 27444290
Ryzhova MV, Zheludkova OG, Kumirova ÉV, Shishkina LV, Panina TN, Gorelyshev SK, Khukhlaeva EA, Mazerkina NA, Matuev KB, Medvedeva OA, Tarasova EM, Kholodov BV, Kapitul'skaia OIu
Zh Vopr Neirokhir Im N N Burdenko 2013;77(1):3-10; discussion 11. PMID: 23659115
Kulchitsky VA, Potkin VI, Zubenko YS, Chernov AN, Talabaev MV, Demidchik YE, Petkevich SK, Kazbanov VV, Gurinovich TA, Roeva MO, Grigoriev DG, Kletskov AV, Kalunov VN
Med Chem 2012 Jan;8(1):22-32. doi: 10.2174/157340612799278298. PMID: 22420547

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