Full Report

Format

Full Report
Summary (Text)
Summary (XML)

Send to:

Choose Destination

File
Clipboard
Collections

Brachial plexus neuropathy

MedGen UID:: 148580
•Concept ID:: C0700251
•: Disease or Syndrome

Synonyms:	Brachial Plexopathy; Brachial Plexus Disease; Brachial Plexus Diseases; Brachial Plexus Disorder; Brachial Plexus Disorders; Brachial Plexus Neuropathies; Brachial Plexus Neuropathy; Neuropathies, Brachial Plexus; Neuropathy, Brachial Plexus; Plexopathies, Brachial; Plexopathy, Brachial; Plexus Disease, Brachial; Plexus Diseases, Brachial; Plexus Disorder, Brachial; Plexus Disorders, Brachial; Plexus Neuropathies, Brachial; Plexus Neuropathy, Brachial
SNOMED CT:	Brachial plexus disorder (3548001); BPN - Brachial plexus neuropathy (3548001); Brachial plexus neuropathy (3548001)

HPO:	HP:0045054
Monarch Initiative:	MONDO:0006683

Definition

A brachial plexus disorder characterized by regional paresthesia, pain and muscle weakness, and limited movement in the arm or hand. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVBrachial plexus neuropathy

Congenital Systemic Disorder
- Abnormality of the nervous system
  - Abnormality of the peripheral nervous system
    - Abnormality of the somatic nervous system
      - Abnormality of somatic nerve plexus
        Abnormality of the brachial nerve plexus
        Brachial plexus neuropathy
        Brachial plexus neuritis
        Neonatal Brachial Plexus Palsy

Conditions with this feature

Amyotrophic neuralgia

MedGen UID:: 320318
•Concept ID:: C1834304
•: Disease or Syndrome

Hereditary neuralgic amyotrophy (HNA) is an autosomal dominant form of recurrent focal neuropathy characterized clinically by acute, recurrent episodes of brachial plexus neuropathy with muscle weakness and atrophy preceded by severe pain in the affected arm.

See: Condition Record

Amyotrophic neuralgia

Professional guidelines

PubMed

Radiation-induced brachial plexus neuropathy - aetiopathogenesis, risk factors, differential diagnostics, symptoms and treatment.

Gosk J, Rutowski R, Reichert P, Rabczyński J
Folia Neuropathol 2007;45(1):26-30. PMID: 17357008

Primary axillary radiotherapy as axillary treatment in breast-conserving therapy for patients with breast carcinoma and clinically negative axillary lymph nodes.

Hoebers FJ, Borger JH, Hart AA, Peterse JL, Th EJ, Lebesque JV
Cancer 2000 Apr 1;88(7):1633-42. doi: 10.1002/(sici)1097-0142(20000401)88:7<1633::aid-cncr18>3.0.co;2-s. PMID: 10738222

The role of diagnostic CT scanning of the brachial plexus and axilla in the follow-up of patients with breast cancer.

Moskovic E, Curtis S, A'Hern RP, Harmer CL, Parsons C
Clin Oncol (R Coll Radiol) 1992 Mar;4(2):74-7. doi: 10.1016/s0936-6555(05)80969-0. PMID: 1554630

See all (6)

Recent clinical studies

Etiology

Early electrodiagnosis in the management of neonatal brachial plexus palsy: A systematic review.

van der Looven R, Le Roy L, Tanghe E, van den Broeck C, de Muynck M, Vingerhoets G, Pitt M, Vanderstraeten G
Muscle Nerve 2020 May;61(5):557-566. Epub 2019 Dec 9 doi: 10.1002/mus.26762. PMID: 31743456

Cerebrospinal fluid profile and seroprevalence of antiganglioside reactivity in patients with neuralgic amyotrophy.

Stich O, Glos D, Brendle M, Dersch R, Rauer S
J Peripher Nerv Syst 2016 Mar;21(1):27-32. doi: 10.1111/jns.12157. PMID: 26757215

Axillary recurrence following conservative surgery and radiotherapy in early breast cancer.

Livsey JE, Magee B, Stewart AL, Swindell R
Clin Oncol (R Coll Radiol) 2000;12(5):309-14. doi: 10.1053/clon.2000.9181. PMID: 11315717

Parsonage-Turner syndrome in the Native American Indian.

Augé WK 2nd, Velázquez PA
J Shoulder Elbow Surg 2000 Mar-Apr;9(2):99-103. PMID: 10810688

Intractable pain with breast cancer.

Watson CP, Evans RJ
Can Med Assoc J 1982 Feb 1;126(3):263-6. PMID: 6277445 Free PMC Article

See all (48)

Diagnosis

Parsonage-Turner Syndrome and Hereditary Brachial Plexus Neuropathy.

Meiling JB, Boon AJ, Niu Z, Howe BM, Hoskote SS, Spinner RJ, Klein CJ
Mayo Clin Proc 2024 Jan;99(1):124-140. doi: 10.1016/j.mayocp.2023.06.011. PMID: 38176820

Early electrodiagnosis in the management of neonatal brachial plexus palsy: A systematic review.

Radiation-induced brachial plexus neuropathy: A review.

Warade AC, Jha AK, Pattankar S, Desai K
Neurol India 2019 Jan-Feb;67(Supplement):S47-S52. doi: 10.4103/0028-3886.250704. PMID: 30688233

Treatment for neonatal neuralgic amyotrophy.

van Eijk JJ, Cuppen I, van Alfen N, Rotteveel JJ
Eur J Paediatr Neurol 2009 May;13(3):283-5. Epub 2008 Jun 20 doi: 10.1016/j.ejpn.2008.04.007. PMID: 18571949

Lumbosacral plexus neuropathy.

Evans BA, Stevens JC, Dyck PJ
Neurology 1981 Oct;31(10):1327-30. doi: 10.1212/wnl.31.10.1327. PMID: 6287351

See all (81)

Therapy

Unilateral brachial plexopathy, a rare complication of Mycoplasma pneumoniae infection.

Robnik B, Keše D, Rojko T, Horvat-Ledinek A, Pražnikar A, Beović B
J Infect Chemother 2018 Apr;24(4):309-311. Epub 2017 Dec 6 doi: 10.1016/j.jiac.2017.11.008. PMID: 29221755

Treatment for neonatal neuralgic amyotrophy.

van Eijk JJ, Cuppen I, van Alfen N, Rotteveel JJ
Eur J Paediatr Neurol 2009 May;13(3):283-5. Epub 2008 Jun 20 doi: 10.1016/j.ejpn.2008.04.007. PMID: 18571949

Bilateral isolated phrenic neuropathy causing painless bilateral diaphragmatic paralysis.

Lin PT, Andersson PB, Distad BJ, Barohn RJ, Cho SC, So YT, Katz JS
Neurology 2005 Nov 8;65(9):1499-501. doi: 10.1212/01.wnl.0000183150.97425.55. PMID: 16275847

Bilateral diaphragmatic weakness: a late complication of radiotherapy.

Brander PE, Järvinen V, Lohela P, Salmi T
Thorax 1997 Sep;52(9):829-31. doi: 10.1136/thx.52.9.829. PMID: 9371219 Free PMC Article

Delayed radiation-induced damage to the brachial plexus.

Burns RJ
Clin Exp Neurol 1978;15:221-7. PMID: 756017

See all (49)

Prognosis

Early electrodiagnosis in the management of neonatal brachial plexus palsy: A systematic review.

Idiopathic neuralgic amyotrophy in children. A distinct phenotype compared to the adult form.

van Alfen N, Schuuring J, van Engelen BG, Rotteveel JJ, Gabreëls FJ
Neuropediatrics 2000 Dec;31(6):328-32. doi: 10.1055/s-2000-12954. PMID: 11508556

Late effects of radiotherapy in the treatment of breast cancer.

Wallgren A
Acta Oncol 1992;31(2):237-42. doi: 10.3109/02841869209088909. PMID: 1622640

The syndrome of Parsonage and Turner. Discussion of clinical features with a review of 8 cases.

Vanermen B, Aertgeerts M, Hoogmartens M, Fabry G
Acta Orthop Belg 1991;57(4):414-9. PMID: 1772018

Intractable pain with breast cancer.

Watson CP, Evans RJ
Can Med Assoc J 1982 Feb 1;126(3):263-6. PMID: 6277445 Free PMC Article

See all (39)

Clinical prediction guides

Neuropathic Pain and Positive Sensory Symptoms in Brachial Plexus Neuropathy: An Exploratory Study of Outcomes after Surgical Decompression and Proposal of a New Sensory Frequency of Symptoms Scale.

García-Jeronimo AI, Armas-Salazar A, García-Muñoz L, Navarro-Olvera JL, Esqueda-Liquidano MA, Carrillo-Ruiz JD
J Integr Neurosci 2023 Jan 17;22(1):25. doi: 10.31083/j.jin2201025. PMID: 36722242

Jin K, Luo J, Wang X, Yang Z, Zhang L, Mei X, Ma J, Chen X, Zhang X, Zhou Z, Wang X, Shao Z, Zhang Z, Guo X, Yu X
Pract Radiat Oncol 2022 Jan-Feb;12(1):e13-e23. Epub 2021 Aug 24 doi: 10.1016/j.prro.2021.08.003. PMID: 34450336

Early electrodiagnosis in the management of neonatal brachial plexus palsy: A systematic review.

Parsonage-Turner syndrome in the Native American Indian.

Augé WK 2nd, Velázquez PA
J Shoulder Elbow Surg 2000 Mar-Apr;9(2):99-103. PMID: 10810688

Late effects of radiotherapy in the treatment of breast cancer.

Wallgren A
Acta Oncol 1992;31(2):237-42. doi: 10.3109/02841869209088909. PMID: 1622640

See all (21)