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Hepatic granuloma

MedGen UID:
155428
•Concept ID:
C0745754
•
Disease or Syndrome
Synonyms: Hepatic Granuloma; hepatic granuloma; Liver Granuloma
SNOMED CT: Hepatic granuloma (714253009)
 
Monarch Initiative: MONDO:0006241

Definition

A granuloma located in the liver. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHepatic granuloma

Professional guidelines

PubMed

The role of microRNAs in the pathogenesis, grading and treatment of hepatic fibrosis in schistosomiasis.
Chen Q, Zhang J, Zheng T, Chen H, Nie H, Zheng B, Gong Q
Parasit Vectors 2019 Dec 30;12(1):611. doi: 10.1186/s13071-019-3866-0. PMID: 31888743Free PMC Article

Recent clinical studies

Etiology

Sodium butyrate ameliorates Schistosoma japonicum-induced liver fibrosis by inhibiting HMGB1 expression.
Chen H, Li G, Zhang J, Zheng T, Chen Q, Zhang Y, Yang F, Wang C, Nie H, Zheng B, Gong Q
Exp Parasitol 2021 Dec;231:108171. Epub 2021 Nov 2 doi: 10.1016/j.exppara.2021.108171. PMID: 34736899
Enhancement of the therapeutic efficacy of praziquantel in murine Schistosomiasis mansoni using silica nanocarrier.
Tawfeek GM, Baki MHA, Ibrahim AN, Mostafa MAH, Fathy MM, Diab MSEDM
Parasitol Res 2019 Dec;118(12):3519-3533. Epub 2019 Oct 31 doi: 10.1007/s00436-019-06475-8. PMID: 31673833
T regulatory cell responses to immunization with a soluble egg antigen in Schistosoma mansoni-infected mice.
El-Ahwany E, Bauiomy IR, Nagy F, Zalat R, Mahmoud O, Zada S
Korean J Parasitol 2012 Mar;50(1):29-35. Epub 2012 Mar 6 doi: 10.3347/kjp.2012.50.1.29. PMID: 22451731Free PMC Article
Hepatic granuloma: decreasing trend in a high-incidence area.
Sanai FM, Ashraf S, Abdo AA, Satti MB, Batwa F, Al-Husseini H, Saleh AM, Bzeizi KI
Liver Int 2008 Dec;28(10):1402-7. doi: 10.1111/j.1478-3231.2008.01837.x. PMID: 18694402
Prevalence of hepatic granulomas in chronic hepatitis B.
Tahan V, Ozaras R, Lacevic N, Ozden E, Yemisen M, Ozdogan O, Mert A, Tabak F, Avsar E, Celikel CA, Ozbay G, Kalayci C, Senturk H, Tozun N
Dig Dis Sci 2004 Oct;49(10):1575-7. doi: 10.1023/b:ddas.0000043366.18578.15. PMID: 15573907

Diagnosis

Potential Gut Microbiota Features for Non-Invasive Detection of Schistosomiasis.
Lin D, Song Q, Liu J, Chen F, Zhang Y, Wu Z, Sun X, Wu X
Front Immunol 2022;13:941530. Epub 2022 Jul 14 doi: 10.3389/fimmu.2022.941530. PMID: 35911697Free PMC Article
FOLFOX and capecitabine-induced hepatic granuloma mimicking metastasis in a rectal cancer patient.
Sarathy V, Kothandath Shankar RK, Mufti SS, Naik R
BMJ Case Rep 2020 Mar 4;13(3) doi: 10.1136/bcr-2019-232628. PMID: 32139448Free PMC Article
The role of microRNAs in the pathogenesis, grading and treatment of hepatic fibrosis in schistosomiasis.
Chen Q, Zhang J, Zheng T, Chen H, Nie H, Zheng B, Gong Q
Parasit Vectors 2019 Dec 30;12(1):611. doi: 10.1186/s13071-019-3866-0. PMID: 31888743Free PMC Article
Enfermedad granulomatosa hepática.
Ortiz-Brizuela E, Azamar-Llamas D, Mora JD, Guerrero-Castillo JI, Martínez-Benítez B, Sifuentes-Osornio J
Gac Med Mex 2019;155(3):266-275. doi: 10.24875/GMM.18004327. PMID: 31219474
Molecular detection of Coxiella burnetii from the formalin-fixed tissues of Q fever patients with acute hepatitis.
Jang YR, Shin Y, Jin CE, Koo B, Park SY, Kim MC, Kim T, Chong YP, Lee SO, Choi SH, Kim YS, Woo JH, Kim SH, Yu E
PLoS One 2017;12(7):e0180237. Epub 2017 Jul 3 doi: 10.1371/journal.pone.0180237. PMID: 28672014Free PMC Article

Therapy

Potential Gut Microbiota Features for Non-Invasive Detection of Schistosomiasis.
Lin D, Song Q, Liu J, Chen F, Zhang Y, Wu Z, Sun X, Wu X
Front Immunol 2022;13:941530. Epub 2022 Jul 14 doi: 10.3389/fimmu.2022.941530. PMID: 35911697Free PMC Article
FOLFOX and capecitabine-induced hepatic granuloma mimicking metastasis in a rectal cancer patient.
Sarathy V, Kothandath Shankar RK, Mufti SS, Naik R
BMJ Case Rep 2020 Mar 4;13(3) doi: 10.1136/bcr-2019-232628. PMID: 32139448Free PMC Article
Enhancement of the therapeutic efficacy of praziquantel in murine Schistosomiasis mansoni using silica nanocarrier.
Tawfeek GM, Baki MHA, Ibrahim AN, Mostafa MAH, Fathy MM, Diab MSEDM
Parasitol Res 2019 Dec;118(12):3519-3533. Epub 2019 Oct 31 doi: 10.1007/s00436-019-06475-8. PMID: 31673833
Lessons from other diseases: granulomatous inflammation in leishmaniasis.
Kaye PM, Beattie L
Semin Immunopathol 2016 Mar;38(2):249-60. Epub 2015 Dec 17 doi: 10.1007/s00281-015-0548-7. PMID: 26678994Free PMC Article
Prevalence of hepatic granulomas in chronic hepatitis B.
Tahan V, Ozaras R, Lacevic N, Ozden E, Yemisen M, Ozdogan O, Mert A, Tabak F, Avsar E, Celikel CA, Ozbay G, Kalayci C, Senturk H, Tozun N
Dig Dis Sci 2004 Oct;49(10):1575-7. doi: 10.1023/b:ddas.0000043366.18578.15. PMID: 15573907

Prognosis

Potential Gut Microbiota Features for Non-Invasive Detection of Schistosomiasis.
Lin D, Song Q, Liu J, Chen F, Zhang Y, Wu Z, Sun X, Wu X
Front Immunol 2022;13:941530. Epub 2022 Jul 14 doi: 10.3389/fimmu.2022.941530. PMID: 35911697Free PMC Article
Hepatic granuloma in Turkish adults: a report of 13 cases.
Onal IK, Ersoy O, Aydinli M, Yonem O, Harmanci O, Sokmensuer C, Bayraktar Y
Eur J Intern Med 2008 Nov;19(7):527-30. Epub 2008 Mar 11 doi: 10.1016/j.ejim.2008.01.012. PMID: 19013382
Hepatic granuloma: decreasing trend in a high-incidence area.
Sanai FM, Ashraf S, Abdo AA, Satti MB, Batwa F, Al-Husseini H, Saleh AM, Bzeizi KI
Liver Int 2008 Dec;28(10):1402-7. doi: 10.1111/j.1478-3231.2008.01837.x. PMID: 18694402
Prevalence of hepatic granulomas in chronic hepatitis B.
Tahan V, Ozaras R, Lacevic N, Ozden E, Yemisen M, Ozdogan O, Mert A, Tabak F, Avsar E, Celikel CA, Ozbay G, Kalayci C, Senturk H, Tozun N
Dig Dis Sci 2004 Oct;49(10):1575-7. doi: 10.1023/b:ddas.0000043366.18578.15. PMID: 15573907
The prevalence of hepatic granulomas in chronic hepatitis C.
Ozaras R, Tahan V, Mert A, Uraz S, Kanat M, Tabak F, Avsar E, Ozbay G, Celikel CA, Tozun N, Senturk H
J Clin Gastroenterol 2004 May-Jun;38(5):449-52. doi: 10.1097/00004836-200405000-00011. PMID: 15100526

Clinical prediction guides

Potential Gut Microbiota Features for Non-Invasive Detection of Schistosomiasis.
Lin D, Song Q, Liu J, Chen F, Zhang Y, Wu Z, Sun X, Wu X
Front Immunol 2022;13:941530. Epub 2022 Jul 14 doi: 10.3389/fimmu.2022.941530. PMID: 35911697Free PMC Article
Spatial and temporal transcriptomics of Schistosoma japonicum-induced hepatic granuloma formation reveals novel roles for neutrophils.
Chuah C, Jones MK, Burke ML, Owen HC, Anthony BJ, McManus DP, Ramm GA, Gobert GN
J Leukoc Biol 2013 Aug;94(2):353-65. Epub 2013 May 24 doi: 10.1189/jlb.1212653. PMID: 23709687
The prevalence of hepatic granulomas in chronic hepatitis C.
Ozaras R, Tahan V, Mert A, Uraz S, Kanat M, Tabak F, Avsar E, Ozbay G, Celikel CA, Tozun N, Senturk H
J Clin Gastroenterol 2004 May-Jun;38(5):449-52. doi: 10.1097/00004836-200405000-00011. PMID: 15100526
Modulation of hepatic granulomatous responses by transgene expression of DAP12 or TREM-1-Ig molecules.
Nochi H, Aoki N, Oikawa K, Yanai M, Takiyama Y, Atsuta Y, Kobayashi H, Sato K, Tateno M, Matsuno T, Katagiri M, Xing Z, Kimura S
Am J Pathol 2003 Apr;162(4):1191-201. doi: 10.1016/S0002-9440(10)63915-6. PMID: 12651611Free PMC Article
The role of cytokines in the formation of the schistosome egg granuloma.
Boros DL
Immunobiology 1994 Oct;191(4-5):441-50. doi: 10.1016/S0171-2985(11)80450-X. PMID: 7713558

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