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Neuroschistosomiasis

MedGen UID:
155718
•Concept ID:
C0752191
•
Disease or Syndrome
Synonyms: Central Nervous System Schistosomiasis; Neuroschistosomiases; Schistosomiasis, Central Nervous System
SNOMED CT: Neuroschistosomiasis (1177012000); Infection of nervous system caused by Schistosoma (1177012000)
 
Monarch Initiative: MONDO:0005874

Definition

Schistosomiasis of the brain, spinal cord, or meninges caused by infections with trematodes of the genus schistosoma (primarily schistosoma japonicum; schistosoma mansoni; and schistosoma haematobium in humans). S. japonicum infections of the nervous system may cause an acute meningoencephalitis or a chronic encephalopathy. S. mansoni and S. haematobium nervous system infections are associated with acute transverse myelitis involving the lower portions of the spinal cord. (From Joynt, Clinical Neurology, 1998, Ch27, pp61-2) [from MONDO]

Professional guidelines

PubMed

Clinical characterization of neuroschistosomiasis due to Schistosoma mansoni and its treatment.
Ferrari TC, Moreira PR, Cunha AS
Acta Trop 2008 Nov-Dec;108(2-3):89-97. Epub 2008 Apr 15 doi: 10.1016/j.actatropica.2008.04.007. PMID: 18499080
Clinical and cerebrospinal fluid (CSF) profile and CSF criteria for the diagnosis of spinal cord schistosomiasis.
Moreno-Carvalho OA, Nascimento-Carvalho CM, Bacelar AL, Andrade-Filho Ade S, Costa G, Fontes JB, Assis T
Arq Neuropsiquiatr 2003 Jun;61(2B):353-8. Epub 2003 Jul 28 doi: 10.1590/s0004-282x2003000300006. PMID: 12894266

Recent clinical studies

Etiology

Imaging of Central Nervous System Parasitic Infections.
Vasconcelos Miranda TA, Tsuchiya K, Lucato LT
Neuroimaging Clin N Am 2023 Feb;33(1):125-146. doi: 10.1016/j.nic.2022.07.013. PMID: 36404040
Mansonic neuroschistosomiasis in the childhood: an undiagnosed pathology?
Dastoli PA, da Costa MDS, Nicácio JM, Pinho RS, Ferrarini MAG, Cavalheiro S
Childs Nerv Syst 2023 Feb;39(2):481-489. Epub 2022 Oct 18 doi: 10.1007/s00381-022-05696-0. PMID: 36258049
Are seizures associated with neuroschistosomiasis mansoni? An exploratory survey in an endemic area of Brazil.
Ferrari TCA, Oliveira AEM, Logato MJS, Ganzella CG, Melo RFQ, Rocha APC, Barbosa FA, Cunha PFS, Silva RAP, Faria LC, Cançado GGL, Couto CA, Cunha AS
Trans R Soc Trop Med Hyg 2022 Aug 5;116(8):704-709. doi: 10.1093/trstmh/trac012. PMID: 35181791
Nested polymerase chain reaction in cerebrospinal fluid for diagnosing spinal cord schistosomiasis: A promising method.
Bruscky IS, de Melo FL, de Medeiros ZM, Albuquerque FF, Wanderley LB, da Cunha-Correia C
J Neurol Sci 2016 Jul 15;366:87-90. Epub 2016 Apr 28 doi: 10.1016/j.jns.2016.04.049. PMID: 27288782
Portal Doppler ultrasound evaluation in myelitis by Schistosoma mansoni.
Vidal CH, Gurgel FV, Ferreira ML, Coutinho AL, Azevedo Filho HR
Arq Neuropsiquiatr 2010 Feb;68(1):67-71. doi: 10.1590/s0004-282x2010000100015. PMID: 20339656

Diagnosis

A tropical myelitis.
Paubel T, Schneider V, Lenfant M, Blanc Labarre C
Neurol Sci 2024 Nov;45(11):5517-5519. Epub 2024 Aug 26 doi: 10.1007/s10072-024-07743-x. PMID: 39183258
Spinal neuroschistosomiasis.
Palin MS, Mathew R, Towns G
Br J Neurosurg 2015;29(4):582-4. Epub 2015 Apr 20 doi: 10.3109/02688697.2015.1016890. PMID: 25891496
Steroids in neuroinfection.
Abraham R
Arq Neuropsiquiatr 2013 Sep;71(9B):717-21. doi: 10.1590/0004-282X20130158. PMID: 24141512
Mansonic neuroschistosomiasis.
Carvalho OA
Arq Neuropsiquiatr 2013 Sep;71(9B):714-6. doi: 10.1590/0004-282X20130157. PMID: 24141511
Diagnosis and management of schistosomiasis.
Gray DJ, Ross AG, Li YS, McManus DP
BMJ 2011 May 17;342:d2651. doi: 10.1136/bmj.d2651. PMID: 21586478Free PMC Article

Therapy

A tropical myelitis.
Paubel T, Schneider V, Lenfant M, Blanc Labarre C
Neurol Sci 2024 Nov;45(11):5517-5519. Epub 2024 Aug 26 doi: 10.1007/s10072-024-07743-x. PMID: 39183258
Pediatric Neuroschistosomiasis: A Case Report and Review of the Literature.
Wen SCH, Anderson R, Ryan MM, Kumbla S, Wray A, Steer A
J Pediatric Infect Dis Soc 2019 Nov 6;8(5):489-491. doi: 10.1093/jpids/piz009. PMID: 30840073
Steroids in neuroinfection.
Abraham R
Arq Neuropsiquiatr 2013 Sep;71(9B):717-21. doi: 10.1590/0004-282X20130158. PMID: 24141512
Neuroschistosomiasis.
Carod-Artal FJ
Expert Rev Anti Infect Ther 2010 Nov;8(11):1307-18. doi: 10.1586/eri.10.111. PMID: 21073294
Neuroschistosomiasis.
Pittella JE
Brain Pathol 1997 Jan;7(1):649-62. doi: 10.1111/j.1750-3639.1997.tb01080.x. PMID: 9034571Free PMC Article

Prognosis

A tropical myelitis.
Paubel T, Schneider V, Lenfant M, Blanc Labarre C
Neurol Sci 2024 Nov;45(11):5517-5519. Epub 2024 Aug 26 doi: 10.1007/s10072-024-07743-x. PMID: 39183258
Spinal cord schistosomiasis: unexpected postmortem finding.
Jaber OI, Kirby PA
Am J Clin Pathol 2013 Jul;140(1):33-6. doi: 10.1309/AJCPQR0ELSAAWJHW. PMID: 23765531
Neuroschistosomiasis mansoni: literature review and guidelines.
Vale TC, de Sousa-Pereira SR, Ribas JG, Lambertucci JR
Neurologist 2012 Nov;18(6):333-42. doi: 10.1097/NRL.0b013e3182704d1e. PMID: 23114664
Neuroschistosomiasis.
Ross AG, McManus DP, Farrar J, Hunstman RJ, Gray DJ, Li YS
J Neurol 2012 Jan;259(1):22-32. Epub 2011 Jun 15 doi: 10.1007/s00415-011-6133-7. PMID: 21674195
Neuroschistosomiasis.
Carod-Artal FJ
Expert Rev Anti Infect Ther 2010 Nov;8(11):1307-18. doi: 10.1586/eri.10.111. PMID: 21073294

Clinical prediction guides

Pseudotumoral Encephalic Schistosomiasis: A Literature Review.
Ibrahim M, Gad K, Khan T, Yousef W, Shabbir Z, Najibullah M, Abodief WT, Jarkhi HH, Azab WA
World Neurosurg 2024 Apr;184:5-13. Epub 2023 Dec 28 doi: 10.1016/j.wneu.2023.12.134. PMID: 38159601
Neuroschistosomiasis: An Unusual Intracranial Space Occupying Lesion.
Manamal NA, Singhal T, Kumar A, Sanghvi D, Mani J
Indian Pediatr 2018 Nov 15;55(11):993-994. PMID: 30587650
Neuroschistosomiasis.
Carod-Artal FJ
Expert Rev Anti Infect Ther 2010 Nov;8(11):1307-18. doi: 10.1586/eri.10.111. PMID: 21073294
Imaging techniques in the evaluation of morbidity in schistosomiasis mansoni.
Lambertucci JR, dos Santos Silva LC, Andrade LM, de Queiroz LC, Carvalho VT, Voieta I, Antunes CM
Acta Trop 2008 Nov-Dec;108(2-3):209-17. Epub 2008 Aug 8 doi: 10.1016/j.actatropica.2008.07.009. PMID: 18760990
Neuroschistosomiasis.
Pittella JE
Brain Pathol 1997 Jan;7(1):649-62. doi: 10.1111/j.1750-3639.1997.tb01080.x. PMID: 9034571Free PMC Article

Recent systematic reviews

Cerebral mansoni schistosomiasis: a systematic review of 33 cases published from 1989 to 2019.
Bruscky IS, Bruscky DMV, de Melo FL, Medeiros ZM, Correia CDC
Trans R Soc Trop Med Hyg 2021 Dec 2;115(12):1410-1413. doi: 10.1093/trstmh/trab067. PMID: 34037805

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