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Cortical Cataract Grade 1

MedGen UID:
1616872
•Concept ID:
C4525727
•
Disease or Syndrome

Definition

A stage of cortical cataract characterized by 10% of the intrapupillary space obscured by opacity. (Modified LOCS II) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCortical Cataract Grade 1

Professional guidelines

PubMed

Corticosteroids for the treatment of Duchenne muscular dystrophy.
Matthews E, Brassington R, Kuntzer T, Jichi F, Manzur AY
Cochrane Database Syst Rev 2016 May 5;2016(5):CD003725. doi: 10.1002/14651858.CD003725.pub4. PMID: 27149418Free PMC Article

Recent clinical studies

Etiology

Corticosteroid therapy for nephrotic syndrome in children.
Hahn D, Samuel SM, Willis NS, Craig JC, Hodson EM
Cochrane Database Syst Rev 2024 Aug 22;8(8):CD001533. doi: 10.1002/14651858.CD001533.pub7. PMID: 39171624Free PMC Article
Systemic medications and cortical cataract: the Singapore Epidemiology of Eye Diseases Study.
Dai W, Tham YC, Chee ML, Majithia S, Poh S, Tan AG, Tao Y, Wang JJ, Cheng CY
Br J Ophthalmol 2020 Mar;104(3):330-335. Epub 2019 Jul 4 doi: 10.1136/bjophthalmol-2019-314256. PMID: 31272959
Corticosteroids for the treatment of Duchenne muscular dystrophy.
Matthews E, Brassington R, Kuntzer T, Jichi F, Manzur AY
Cochrane Database Syst Rev 2016 May 5;2016(5):CD003725. doi: 10.1002/14651858.CD003725.pub4. PMID: 27149418Free PMC Article
Cataract and quality of life in patients with glaucoma.
Skalicky SE, Martin KR, Fenwick E, Crowston JG, Goldberg I, McCluskey P
Clin Exp Ophthalmol 2015 May-Jun;43(4):335-41. Epub 2014 Oct 30 doi: 10.1111/ceo.12454. PMID: 25294739
The Lens Opacities Classification System III. The Longitudinal Study of Cataract Study Group.
Chylack LT Jr, Wolfe JK, Singer DM, Leske MC, Bullimore MA, Bailey IL, Friend J, McCarthy D, Wu SY
Arch Ophthalmol 1993 Jun;111(6):831-6. doi: 10.1001/archopht.1993.01090060119035. PMID: 8512486

Diagnosis

Corticosteroid therapy for nephrotic syndrome in children.
Hahn D, Samuel SM, Willis NS, Craig JC, Hodson EM
Cochrane Database Syst Rev 2024 Aug 22;8(8):CD001533. doi: 10.1002/14651858.CD001533.pub7. PMID: 39171624Free PMC Article
Lens Opacities Classification System III-based artificial intelligence program for automatic cataract grading.
Lu Q, Wei L, He W, Zhang K, Wang J, Zhang Y, Rong X, Zhao Z, Cai L, He X, Wu J, Ding D, Lu Y, Zhu X
J Cataract Refract Surg 2022 May 1;48(5):528-534. doi: 10.1097/j.jcrs.0000000000000790. PMID: 34433780
Double-pass technique and compensation-comparison method in eyes with cataract.
Martínez-Roda JA, Vilaseca M, Ondategui JC, Almudí L, Asaad M, Mateos-Pena L, Arjona M, Pujol J
J Cataract Refract Surg 2016 Oct;42(10):1461-1469. doi: 10.1016/j.jcrs.2016.08.015. PMID: 27839601
Corticosteroids for the treatment of Duchenne muscular dystrophy.
Matthews E, Brassington R, Kuntzer T, Jichi F, Manzur AY
Cochrane Database Syst Rev 2016 May 5;2016(5):CD003725. doi: 10.1002/14651858.CD003725.pub4. PMID: 27149418Free PMC Article
Influence of cataract morphology on straylight and contrast sensitivity and its relevance to fitness to drive.
Bal T, Coeckelbergh T, Van Looveren J, Rozema JJ, Tassignon MJ
Ophthalmologica 2011;225(2):105-11. Epub 2010 Sep 24 doi: 10.1159/000317076. PMID: 20881445

Therapy

Corticosteroid therapy for nephrotic syndrome in children.
Hahn D, Samuel SM, Willis NS, Craig JC, Hodson EM
Cochrane Database Syst Rev 2024 Aug 22;8(8):CD001533. doi: 10.1002/14651858.CD001533.pub7. PMID: 39171624Free PMC Article
Systemic medications and cortical cataract: the Singapore Epidemiology of Eye Diseases Study.
Dai W, Tham YC, Chee ML, Majithia S, Poh S, Tan AG, Tao Y, Wang JJ, Cheng CY
Br J Ophthalmol 2020 Mar;104(3):330-335. Epub 2019 Jul 4 doi: 10.1136/bjophthalmol-2019-314256. PMID: 31272959
Evaluating the associations between obesity and age-related cataract: a Mendelian randomization study.
Tan AG, Kifley A, Flood VM, Holliday EG, Scott RJ, Cumming RG, Mitchell P, Wang JJ
Am J Clin Nutr 2019 Oct 1;110(4):969-976. doi: 10.1093/ajcn/nqz167. PMID: 31401654
Corticosteroids for the treatment of Duchenne muscular dystrophy.
Matthews E, Brassington R, Kuntzer T, Jichi F, Manzur AY
Cochrane Database Syst Rev 2016 May 5;2016(5):CD003725. doi: 10.1002/14651858.CD003725.pub4. PMID: 27149418Free PMC Article
Use of inhaled and oral corticosteroids and the long-term risk of cataract.
Wang JJ, Rochtchina E, Tan AG, Cumming RG, Leeder SR, Mitchell P
Ophthalmology 2009 Apr;116(4):652-7. Epub 2009 Feb 25 doi: 10.1016/j.ophtha.2008.12.001. PMID: 19243828

Prognosis

Corticosteroid therapy for nephrotic syndrome in children.
Hahn D, Samuel SM, Willis NS, Craig JC, Hodson EM
Cochrane Database Syst Rev 2024 Aug 22;8(8):CD001533. doi: 10.1002/14651858.CD001533.pub7. PMID: 39171624Free PMC Article
Lens Opacities Classification System III-based artificial intelligence program for automatic cataract grading.
Lu Q, Wei L, He W, Zhang K, Wang J, Zhang Y, Rong X, Zhao Z, Cai L, He X, Wu J, Ding D, Lu Y, Zhu X
J Cataract Refract Surg 2022 May 1;48(5):528-534. doi: 10.1097/j.jcrs.0000000000000790. PMID: 34433780
Systemic medications and cortical cataract: the Singapore Epidemiology of Eye Diseases Study.
Dai W, Tham YC, Chee ML, Majithia S, Poh S, Tan AG, Tao Y, Wang JJ, Cheng CY
Br J Ophthalmol 2020 Mar;104(3):330-335. Epub 2019 Jul 4 doi: 10.1136/bjophthalmol-2019-314256. PMID: 31272959
Subfoveal choroidal thickness and cataract: the Beijing Eye Study 2011.
Shao L, Xu L, Zhang JS, You QS, Chen CX, Wang YX, Jonas JB, Wei WB
Invest Ophthalmol Vis Sci 2015 Jan 20;56(2):810-5. doi: 10.1167/iovs.14-15736. PMID: 25604689
Myopia and incident cataract and cataract surgery: the blue mountains eye study.
Younan C, Mitchell P, Cumming RG, Rochtchina E, Wang JJ
Invest Ophthalmol Vis Sci 2002 Dec;43(12):3625-32. PMID: 12454028

Clinical prediction guides

Lens Opacities Classification System III-based artificial intelligence program for automatic cataract grading.
Lu Q, Wei L, He W, Zhang K, Wang J, Zhang Y, Rong X, Zhao Z, Cai L, He X, Wu J, Ding D, Lu Y, Zhu X
J Cataract Refract Surg 2022 May 1;48(5):528-534. doi: 10.1097/j.jcrs.0000000000000790. PMID: 34433780
Aldose Reductase Polymorphisms, Fasting Blood Glucose, and Age-Related Cortical Cataract.
Tan AG, Kifley A, Holliday EG, Klein BEK, Iyengar SK, Lee KE, Jun GR, Cumming RG, Zhao W, Wong TY, Cheng CY, Mitchell P, Wang JJ
Invest Ophthalmol Vis Sci 2018 Sep 4;59(11):4755-4762. doi: 10.1167/iovs.18-24353. PMID: 30267098
Corticosteroids for the treatment of Duchenne muscular dystrophy.
Matthews E, Brassington R, Kuntzer T, Jichi F, Manzur AY
Cochrane Database Syst Rev 2016 May 5;2016(5):CD003725. doi: 10.1002/14651858.CD003725.pub4. PMID: 27149418Free PMC Article
Cataract and quality of life in patients with glaucoma.
Skalicky SE, Martin KR, Fenwick E, Crowston JG, Goldberg I, McCluskey P
Clin Exp Ophthalmol 2015 May-Jun;43(4):335-41. Epub 2014 Oct 30 doi: 10.1111/ceo.12454. PMID: 25294739
The Lens Opacities Classification System III. The Longitudinal Study of Cataract Study Group.
Chylack LT Jr, Wolfe JK, Singer DM, Leske MC, Bullimore MA, Bailey IL, Friend J, McCarthy D, Wu SY
Arch Ophthalmol 1993 Jun;111(6):831-6. doi: 10.1001/archopht.1993.01090060119035. PMID: 8512486

Recent systematic reviews

Corticosteroid therapy for nephrotic syndrome in children.
Hahn D, Samuel SM, Willis NS, Craig JC, Hodson EM
Cochrane Database Syst Rev 2024 Aug 22;8(8):CD001533. doi: 10.1002/14651858.CD001533.pub7. PMID: 39171624Free PMC Article
Efficacy and Safety of Corticosteroid Implants in Non-infectious Uveitis: A Systematic Review with Network Meta-analysis.
Vieira R, Sousa-Pinto B, Figueira L
Ocul Immunol Inflamm 2022 Jan 2;30(1):215-222. Epub 2020 Aug 18 doi: 10.1080/09273948.2020.1787463. PMID: 32809890
Defining outcome measures in juvenile idiopathic arthritis associated uveitis by a systematic review analysis: do we need a consensus?
Mastrangelo G, Foeldvari I, Anton J, Simonini G
Pediatr Rheumatol Online J 2019 Jul 11;17(1):40. doi: 10.1186/s12969-019-0330-9. PMID: 31296236Free PMC Article
Non-steroidal anti-inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract surgery.
Juthani VV, Clearfield E, Chuck RS
Cochrane Database Syst Rev 2017 Jul 3;7(7):CD010516. doi: 10.1002/14651858.CD010516.pub2. PMID: 28670710Free PMC Article
Corticosteroids for the treatment of Duchenne muscular dystrophy.
Matthews E, Brassington R, Kuntzer T, Jichi F, Manzur AY
Cochrane Database Syst Rev 2016 May 5;2016(5):CD003725. doi: 10.1002/14651858.CD003725.pub4. PMID: 27149418Free PMC Article

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