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Separate origin of the left anterior descending and left circumflex artery

MedGen UID:
1618482
•Concept ID:
C4531059
•
Anatomical Abnormality
HPO: HP:0031536

Definition

Anomalous coronary origin whereby the left anterior descending (LAD) and the left circumflex artery (LCX) arise separately. Normally, these arteries arise from a common stem, the left main coronary artery (LMCA). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSeparate origin of the left anterior descending and left circumflex artery

Recent clinical studies

Therapy

Congenital anomalous aortic origins of the coronary arteries in adults: a Tunisian coronary arteriography study.
Ouali S, Neffeti E, Sendid K, Elghoul K, Remedi F, Boughzela E
Arch Cardiovasc Dis 2009 Mar;102(3):201-8. Epub 2009 Mar 17 doi: 10.1016/j.acvd.2009.01.001. PMID: 19375674
Multiple coronary to left ventricular fistulae.
Sambu N, Sharma R, Kalra PR
Eur J Echocardiogr 2009 Mar;10(2):352. Epub 2008 Aug 27 doi: 10.1093/ejechocard/jen229. PMID: 18755698
Separate origins of three coronary arteries arising from the right sinus of Valsalva.
Miyoshi S, Hara Y, Shigenmatsu Y, Ohtsuka T, Ogimoto A, Ohkura T, Higaki J
Can J Cardiol 2005 Apr;21(5):451-2. PMID: 15861264

Prognosis

Is the Prevalence of Coronary Artery Anomalies Different in Countries with Small Populations? - A Retrospective Study in Northern Cyprus.
Muhtaroglu M, Lafci Fahrioglu S, Beton O, İlgi S
Heart Surg Forum 2021 Dec 14;24(6):E1027-E1032. doi: 10.1532/hsf.4203. PMID: 34962469
Prevalence and patterns of coronary artery anomalies in 28,800 adult patients undergoing angiography in a large tertiary care centre in India.
Bansal A, Sarkar PG, Gupta MD, Girish MP, Kunal S, Batra V, Yusuf J, Safal, Mukhopadhyay S, Tyagi S
Monaldi Arch Chest Dis 2021 Dec 16;92(3) doi: 10.4081/monaldi.2021.2066. PMID: 34918500
Anomalous left anterior descending artery diagnosed on pulmonary artery computed tomography.
Kim J, Bergman T, Juergens AL
Am J Emerg Med 2019 Jul;37(7):1396.e5-1396.e7. Epub 2019 Apr 12 doi: 10.1016/j.ajem.2019.04.028. PMID: 31006604
Gender differences in the types and frequency of coronary artery anomalies.
Aydar Y, Yazici HU, Birdane A, Nasifov M, Nadir A, Ulus T, Göktekin O, Gorenek B, Unalir A
Tohoku J Exp Med 2011 Dec;225(4):239-47. doi: 10.1620/tjem.225.239. PMID: 22056781
Identification, imaging, functional assessment and management of congenital coronary arterial abnormalities in children.
Friedman AH, Fogel MA, Stephens P Jr, Hellinger JC, Nykanen DG, Tweddell J, Feltes TF, Rome JJ
Cardiol Young 2007 Sep;17 Suppl 2:56-67. doi: 10.1017/S1047951107001163. PMID: 18039399

Clinical prediction guides

The incidence of coronary anomalies on routine coronary computed tomography scans.
Karabay KO, Yildiz A, Geceer G, Uysal E, Bagirtan B
Cardiovasc J Afr 2013 Oct-Nov;24(9-10):351-4. Epub 2013 Sep 11 doi: 10.5830/CVJA-2013-066. PMID: 24042853Free PMC Article
The prevalence of coronary artery variations on coronary computed tomography angiography.
Erol C, Seker M
Acta Radiol 2012 Apr 1;53(3):278-84. Epub 2012 Feb 8 doi: 10.1258/ar.2011.110394. PMID: 22319132
Prevalence of anomalous origin of coronary artery detected by multi-detector computed tomography at one center.
Fujimoto S, Kondo T, Orihara T, Sugiyama J, Kondo M, Kodama T, Fukazawa H, Nagaoka H, Oida A, Yamazaki J, Takase S
J Cardiol 2011 Jan;57(1):69-76. Epub 2010 Dec 10 doi: 10.1016/j.jjcc.2010.10.006. PMID: 21146363
Detection of coronary artery anomalies and coronary aneurysms by multislice computed tomography coronary angiography.
Castorina S, Privitera G, Luca T, Panebianco M, Tolaro S, Patanè L, Riccioli V
Ital J Anat Embryol 2009 Apr-Sep;114(2-3):77-86. PMID: 20198820
Anatomy of the coronary arteries in transposition of the great arteries and methods for their transfer in anatomical correction.
Yacoub MH, Radley-Smith R
Thorax 1978 Aug;33(4):418-24. doi: 10.1136/thx.33.4.418. PMID: 694795Free PMC Article

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