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Lichenoid skin lesion

MedGen UID:
1627159
•Concept ID:
C4531107
•
Anatomical Abnormality
HPO: HP:0031452

Definition

Multiple skin lesions resembling those characteristic of the disease lichen planus. These lesions are violaceous (reddish-purple), shiny, isolated, flat-topped papules and plaques. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLichenoid skin lesion

Professional guidelines

PubMed

Adverse cutaneous toxicities by PD-1/PD-L1 immune checkpoint inhibitors: pathogenesis, treatment, and surveillance.
Bhardwaj M, Chiu MN, Pilkhwal Sah S
Cutan Ocul Toxicol 2022 Mar;41(1):73-90. Epub 2022 Feb 20 doi: 10.1080/15569527.2022.2034842. PMID: 35107396
Cutaneous Immune-Related Adverse Events (irAEs) to Immune Checkpoint Inhibitors: A Dermatology Perspective on Management [Formula: see text].
Muntyanu A, Netchiporouk E, Gerstein W, Gniadecki R, Litvinov IV
J Cutan Med Surg 2021 Jan-Feb;25(1):59-76. Epub 2020 Aug 3 doi: 10.1177/1203475420943260. PMID: 32746624
Pityriasis Rosea: Diagnosis and Treatment.
Villalon-Gomez JM
Am Fam Physician 2018 Jan 1;97(1):38-44. PMID: 29365241

Recent clinical studies

Etiology

Adverse cutaneous toxicities by PD-1/PD-L1 immune checkpoint inhibitors: pathogenesis, treatment, and surveillance.
Bhardwaj M, Chiu MN, Pilkhwal Sah S
Cutan Ocul Toxicol 2022 Mar;41(1):73-90. Epub 2022 Feb 20 doi: 10.1080/15569527.2022.2034842. PMID: 35107396
Hyaline Inclusion Acanthoma.
Tran TAN, Parra O, Linos K
Am J Dermatopathol 2021 Jul 1;43(7):525-529. doi: 10.1097/DAD.0000000000001927. PMID: 33606370
Dermatologic Reactions to Immune Checkpoint Inhibitors : Skin Toxicities and Immunotherapy.
Sibaud V
Am J Clin Dermatol 2018 Jun;19(3):345-361. doi: 10.1007/s40257-017-0336-3. PMID: 29256113
Granulomatous & histiocytic dermatitides.
Wick MR
Semin Diagn Pathol 2017 May;34(3):301-311. Epub 2016 Dec 14 doi: 10.1053/j.semdp.2016.12.003. PMID: 28094163
Cutaneous and mucosal lichen planus: a comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis.
Gorouhi F, Davari P, Fazel N
ScientificWorldJournal 2014;2014:742826. Epub 2014 Jan 30 doi: 10.1155/2014/742826. PMID: 24672362Free PMC Article

Diagnosis

Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails.
Lacouture M, Sibaud V
Am J Clin Dermatol 2018 Nov;19(Suppl 1):31-39. doi: 10.1007/s40257-018-0384-3. PMID: 30374901Free PMC Article
Pityriasis Rosea: Diagnosis and Treatment.
Villalon-Gomez JM
Am Fam Physician 2018 Jan 1;97(1):38-44. PMID: 29365241
Dermatologic Reactions to Immune Checkpoint Inhibitors : Skin Toxicities and Immunotherapy.
Sibaud V
Am J Clin Dermatol 2018 Jun;19(3):345-361. doi: 10.1007/s40257-017-0336-3. PMID: 29256113
Oral lichen planus: a literature review and update.
Alrashdan MS, Cirillo N, McCullough M
Arch Dermatol Res 2016 Oct;308(8):539-51. Epub 2016 Jun 27 doi: 10.1007/s00403-016-1667-2. PMID: 27349424
Cutaneous and mucosal lichen planus: a comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis.
Gorouhi F, Davari P, Fazel N
ScientificWorldJournal 2014;2014:742826. Epub 2014 Jan 30 doi: 10.1155/2014/742826. PMID: 24672362Free PMC Article

Therapy

Adverse cutaneous toxicities by PD-1/PD-L1 immune checkpoint inhibitors: pathogenesis, treatment, and surveillance.
Bhardwaj M, Chiu MN, Pilkhwal Sah S
Cutan Ocul Toxicol 2022 Mar;41(1):73-90. Epub 2022 Feb 20 doi: 10.1080/15569527.2022.2034842. PMID: 35107396
Cutaneous Immune-Related Adverse Events (irAEs) to Immune Checkpoint Inhibitors: A Dermatology Perspective on Management [Formula: see text].
Muntyanu A, Netchiporouk E, Gerstein W, Gniadecki R, Litvinov IV
J Cutan Med Surg 2021 Jan-Feb;25(1):59-76. Epub 2020 Aug 3 doi: 10.1177/1203475420943260. PMID: 32746624
Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails.
Lacouture M, Sibaud V
Am J Clin Dermatol 2018 Nov;19(Suppl 1):31-39. doi: 10.1007/s40257-018-0384-3. PMID: 30374901Free PMC Article
Pityriasis Rosea: Diagnosis and Treatment.
Villalon-Gomez JM
Am Fam Physician 2018 Jan 1;97(1):38-44. PMID: 29365241
Dermatologic Reactions to Immune Checkpoint Inhibitors : Skin Toxicities and Immunotherapy.
Sibaud V
Am J Clin Dermatol 2018 Jun;19(3):345-361. doi: 10.1007/s40257-017-0336-3. PMID: 29256113

Prognosis

Diagnostic histochemistry in non-neoplastic skin diseases.
Wick MR, Patterson JW
Semin Diagn Pathol 2018 Nov;35(6):390-398. Epub 2018 Oct 16 doi: 10.1053/j.semdp.2018.10.006. PMID: 30509350
Pityriasis Rosea: Diagnosis and Treatment.
Villalon-Gomez JM
Am Fam Physician 2018 Jan 1;97(1):38-44. PMID: 29365241
Dermatologic Reactions to Immune Checkpoint Inhibitors : Skin Toxicities and Immunotherapy.
Sibaud V
Am J Clin Dermatol 2018 Jun;19(3):345-361. doi: 10.1007/s40257-017-0336-3. PMID: 29256113
Cutaneous and mucosal lichen planus: a comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis.
Gorouhi F, Davari P, Fazel N
ScientificWorldJournal 2014;2014:742826. Epub 2014 Jan 30 doi: 10.1155/2014/742826. PMID: 24672362Free PMC Article
Mucha-Habermann disease.
Bica BE, de Barros Mda G, Spingola C Jr
Rev Bras Reumatol 2013 May-Jun;53(3):314-7. doi: 10.1590/s0482-50042013000300011. PMID: 24051916

Clinical prediction guides

Diagnostic histochemistry in non-neoplastic skin diseases.
Wick MR, Patterson JW
Semin Diagn Pathol 2018 Nov;35(6):390-398. Epub 2018 Oct 16 doi: 10.1053/j.semdp.2018.10.006. PMID: 30509350
Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails.
Lacouture M, Sibaud V
Am J Clin Dermatol 2018 Nov;19(Suppl 1):31-39. doi: 10.1007/s40257-018-0384-3. PMID: 30374901Free PMC Article
Dermatologic Reactions to Immune Checkpoint Inhibitors : Skin Toxicities and Immunotherapy.
Sibaud V
Am J Clin Dermatol 2018 Jun;19(3):345-361. doi: 10.1007/s40257-017-0336-3. PMID: 29256113
Dermatoscopy in inflammatory and infectious skin disorders.
Lacarrubba F, Verzì AE, Dinotta F, Scavo S, Micali G
G Ital Dermatol Venereol 2015 Oct;150(5):521-31. PMID: 26333553
Delayed cutaneous manifestations of drug hypersensitivity.
Bircher AJ, Scherer K
Med Clin North Am 2010 Jul;94(4):711-25, x. doi: 10.1016/j.mcna.2010.04.001. PMID: 20609859

Recent systematic reviews

Lichen planus pemphigoides with predominant mucous membrane involvement: a series of 12 patients and a literature review.
Combemale L, Bohelay G, Sitbon IY, Ahouach B, Alexandre M, Martin A, Pascal F, Soued I, Doan S, Morin F, Grootenboer-Mignot S, Caux F, Prost-Squarcioni C, Le Roux-Villet C
Front Immunol 2024;15:1243566. Epub 2024 Apr 15 doi: 10.3389/fimmu.2024.1243566. PMID: 38686381Free PMC Article
A systematic review and meta-analysis of the regional and age-related differences in atopic dermatitis clinical characteristics.
Yew YW, Thyssen JP, Silverberg JI
J Am Acad Dermatol 2019 Feb;80(2):390-401. Epub 2018 Oct 1 doi: 10.1016/j.jaad.2018.09.035. PMID: 30287309
Lymphomatoid Papulosis in Children and Adolescents: A Systematic Review.
Wieser I, Wohlmuth C, Nunez CA, Duvic M
Am J Clin Dermatol 2016 Aug;17(4):319-27. doi: 10.1007/s40257-016-0192-6. PMID: 27138554
Urban legends series: lichen planus.
Baccaglini L, Thongprasom K, Carrozzo M, Bigby M
Oral Dis 2013 Mar;19(2):128-43. Epub 2012 Jul 13 doi: 10.1111/j.1601-0825.2012.01953.x. PMID: 22788669
Chronic ulcerative stomatitis: diagnostic and management challenges--four new cases and review of literature.
Islam MN, Cohen DM, Ojha J, Stewart CM, Katz J, Bhattacharyya I
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007 Aug;104(2):194-203. Epub 2007 Jun 7 doi: 10.1016/j.tripleo.2007.02.013. PMID: 17560144

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