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Grade 1 Esophageal Hemorrhage, CTCAE

MedGen UID:
1632036
•Concept ID:
C4685127
•
Finding

Definition

Mild symptoms; intervention not indicated [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 1 Esophageal Hemorrhage, CTCAE

Recent clinical studies

Etiology

The efficacy and safety of definitive concurrent chemoradiotherapy for non-operable esophageal cancer.
Dreyfuss AD, Barsky AR, Wileyto EP, Eads JR, Kucharczuk JC, Williams NN, Karasic TB, Metz JM, Ben-Josef E, Plastaras JP, Wojcieszynski AP
Cancer Med 2021 Feb;10(4):1275-1288. Epub 2021 Jan 20 doi: 10.1002/cam4.3724. PMID: 33474812Free PMC Article
Cisplatin and 5-fluorouracil with or without epidermal growth factor receptor inhibition panitumumab for patients with non-resectable, advanced or metastatic oesophageal squamous cell cancer: a prospective, open-label, randomised phase III AIO/EORTC trial (POWER).
Moehler M, Maderer A, Thuss-Patience PC, Brenner B, Meiler J, Ettrich TJ, Hofheinz RD, Al-Batran SE, Vogel A, Mueller L, Lutz MP, Lordick F, Alsina M, Borchert K, Greil R, Eisterer W, Schad A, Slotta-Huspenina J, Van Cutsem E, Lorenzen S
Ann Oncol 2020 Feb;31(2):228-235. Epub 2019 Dec 16 doi: 10.1016/j.annonc.2019.10.018. PMID: 31959339
Anti-PD1 antibodies in patients aged ≥ 75 years with metastatic melanoma: A retrospective multicentre study.
Ridolfi L, De Rosa F, Petracci E, Tanda ET, Marra E, Pigozzo J, Marconcini R, Guida M, Cappellini GCA, Gallizzi G, Occelli M, Pala L, Gambale E, Bersanelli M, Galdo G, Cortellini A, Morgese F, Zoratto F, Stucci LS, Strippoli S, Guidoboni M; Italian Melanoma Intergroup (IMI)
J Geriatr Oncol 2020 Apr;11(3):515-522. Epub 2020 Jan 9 doi: 10.1016/j.jgo.2019.12.012. PMID: 31928943
Radiation-related Adverse Effects of CT-guided Implantation of (125)I Seeds for Thoracic Recurrent and/or Metastatic Malignancy.
Ji Z, Jiang Y, Guo F, Peng R, Sun H, Wang P, Fan J, Wang J
Sci Rep 2019 Oct 15;9(1):14803. doi: 10.1038/s41598-019-51458-5. PMID: 31616052Free PMC Article
Continuous hyperfractionated accelerated radiotherapy - Escalated dose (CHART-ED): A phase I study.
Hatton MQ, Hill R, Fenwick JD, Morgan SA, Wilson PC, Atherton PJ, Dickson J, Murray KE, Paul J
Radiother Oncol 2016 Mar;118(3):471-7. Epub 2015 Dec 11 doi: 10.1016/j.radonc.2015.11.015. PMID: 26687902

Diagnosis

Adjuvant Treatment with S-1 in Patients after R0-Resection of Adenocarcinoma of the Stomach and Esophagogastric Junction: A Multicenter Phase I/II Feasibility Study (GMBH-STO-0114).
Heinrich K, Heinemann V, Stintzing S, Müller L, Ettrich TJ, Büchner-Steudel P, Geißler M, Trojan J, Moosmann N, Folprecht G, Schmidt J, Kanzler S, Kullmann F, Moulin JC, Werner J, Angele MK, Probst V, Held S, Schulz C, Boukovala M
Oncol Res Treat 2024;47(6):251-261. Epub 2024 Apr 2 doi: 10.1159/000538143. PMID: 38565089Free PMC Article

Therapy

The efficacy and safety of definitive concurrent chemoradiotherapy for non-operable esophageal cancer.
Dreyfuss AD, Barsky AR, Wileyto EP, Eads JR, Kucharczuk JC, Williams NN, Karasic TB, Metz JM, Ben-Josef E, Plastaras JP, Wojcieszynski AP
Cancer Med 2021 Feb;10(4):1275-1288. Epub 2021 Jan 20 doi: 10.1002/cam4.3724. PMID: 33474812Free PMC Article
Cisplatin and 5-fluorouracil with or without epidermal growth factor receptor inhibition panitumumab for patients with non-resectable, advanced or metastatic oesophageal squamous cell cancer: a prospective, open-label, randomised phase III AIO/EORTC trial (POWER).
Moehler M, Maderer A, Thuss-Patience PC, Brenner B, Meiler J, Ettrich TJ, Hofheinz RD, Al-Batran SE, Vogel A, Mueller L, Lutz MP, Lordick F, Alsina M, Borchert K, Greil R, Eisterer W, Schad A, Slotta-Huspenina J, Van Cutsem E, Lorenzen S
Ann Oncol 2020 Feb;31(2):228-235. Epub 2019 Dec 16 doi: 10.1016/j.annonc.2019.10.018. PMID: 31959339
Anti-PD1 antibodies in patients aged ≥ 75 years with metastatic melanoma: A retrospective multicentre study.
Ridolfi L, De Rosa F, Petracci E, Tanda ET, Marra E, Pigozzo J, Marconcini R, Guida M, Cappellini GCA, Gallizzi G, Occelli M, Pala L, Gambale E, Bersanelli M, Galdo G, Cortellini A, Morgese F, Zoratto F, Stucci LS, Strippoli S, Guidoboni M; Italian Melanoma Intergroup (IMI)
J Geriatr Oncol 2020 Apr;11(3):515-522. Epub 2020 Jan 9 doi: 10.1016/j.jgo.2019.12.012. PMID: 31928943
Radiation-related Adverse Effects of CT-guided Implantation of (125)I Seeds for Thoracic Recurrent and/or Metastatic Malignancy.
Ji Z, Jiang Y, Guo F, Peng R, Sun H, Wang P, Fan J, Wang J
Sci Rep 2019 Oct 15;9(1):14803. doi: 10.1038/s41598-019-51458-5. PMID: 31616052Free PMC Article
Continuous hyperfractionated accelerated radiotherapy - Escalated dose (CHART-ED): A phase I study.
Hatton MQ, Hill R, Fenwick JD, Morgan SA, Wilson PC, Atherton PJ, Dickson J, Murray KE, Paul J
Radiother Oncol 2016 Mar;118(3):471-7. Epub 2015 Dec 11 doi: 10.1016/j.radonc.2015.11.015. PMID: 26687902

Prognosis

The efficacy and safety of definitive concurrent chemoradiotherapy for non-operable esophageal cancer.
Dreyfuss AD, Barsky AR, Wileyto EP, Eads JR, Kucharczuk JC, Williams NN, Karasic TB, Metz JM, Ben-Josef E, Plastaras JP, Wojcieszynski AP
Cancer Med 2021 Feb;10(4):1275-1288. Epub 2021 Jan 20 doi: 10.1002/cam4.3724. PMID: 33474812Free PMC Article
Anti-PD1 antibodies in patients aged ≥ 75 years with metastatic melanoma: A retrospective multicentre study.
Ridolfi L, De Rosa F, Petracci E, Tanda ET, Marra E, Pigozzo J, Marconcini R, Guida M, Cappellini GCA, Gallizzi G, Occelli M, Pala L, Gambale E, Bersanelli M, Galdo G, Cortellini A, Morgese F, Zoratto F, Stucci LS, Strippoli S, Guidoboni M; Italian Melanoma Intergroup (IMI)
J Geriatr Oncol 2020 Apr;11(3):515-522. Epub 2020 Jan 9 doi: 10.1016/j.jgo.2019.12.012. PMID: 31928943
Multicentre phase II pharmacokinetic and pharmacodynamic study of OSI-7904L in previously untreated patients with advanced gastric or gastroesophageal junction adenocarcinoma.
Falk S, Anthoney A, Eatock M, Van Cutsem E, Chick J, Glen H, Valle JW, Drolet DW, Albert D, Ferry D, Ajani J
Br J Cancer 2006 Aug 21;95(4):450-6. Epub 2006 Aug 1 doi: 10.1038/sj.bjc.6603267. PMID: 16880795Free PMC Article

Clinical prediction guides

Adjuvant Treatment with S-1 in Patients after R0-Resection of Adenocarcinoma of the Stomach and Esophagogastric Junction: A Multicenter Phase I/II Feasibility Study (GMBH-STO-0114).
Heinrich K, Heinemann V, Stintzing S, Müller L, Ettrich TJ, Büchner-Steudel P, Geißler M, Trojan J, Moosmann N, Folprecht G, Schmidt J, Kanzler S, Kullmann F, Moulin JC, Werner J, Angele MK, Probst V, Held S, Schulz C, Boukovala M
Oncol Res Treat 2024;47(6):251-261. Epub 2024 Apr 2 doi: 10.1159/000538143. PMID: 38565089Free PMC Article
Anti-PD1 antibodies in patients aged ≥ 75 years with metastatic melanoma: A retrospective multicentre study.
Ridolfi L, De Rosa F, Petracci E, Tanda ET, Marra E, Pigozzo J, Marconcini R, Guida M, Cappellini GCA, Gallizzi G, Occelli M, Pala L, Gambale E, Bersanelli M, Galdo G, Cortellini A, Morgese F, Zoratto F, Stucci LS, Strippoli S, Guidoboni M; Italian Melanoma Intergroup (IMI)
J Geriatr Oncol 2020 Apr;11(3):515-522. Epub 2020 Jan 9 doi: 10.1016/j.jgo.2019.12.012. PMID: 31928943
Continuous hyperfractionated accelerated radiotherapy - Escalated dose (CHART-ED): A phase I study.
Hatton MQ, Hill R, Fenwick JD, Morgan SA, Wilson PC, Atherton PJ, Dickson J, Murray KE, Paul J
Radiother Oncol 2016 Mar;118(3):471-7. Epub 2015 Dec 11 doi: 10.1016/j.radonc.2015.11.015. PMID: 26687902
Multicentre phase II pharmacokinetic and pharmacodynamic study of OSI-7904L in previously untreated patients with advanced gastric or gastroesophageal junction adenocarcinoma.
Falk S, Anthoney A, Eatock M, Van Cutsem E, Chick J, Glen H, Valle JW, Drolet DW, Albert D, Ferry D, Ajani J
Br J Cancer 2006 Aug 21;95(4):450-6. Epub 2006 Aug 1 doi: 10.1038/sj.bjc.6603267. PMID: 16880795Free PMC Article

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