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Tumor Hemorrhage, CTCAE

MedGen UID:
1632998
Concept ID:
C4554656
Finding

Definition

A disorder characterized by bleeding in a tumor. [from NCI]

Professional guidelines

PubMed

Nilsson MP, Johnsson A, Scherman J
Radiat Oncol 2021 Aug 16;16(1):152. doi: 10.1186/s13014-021-01876-5. PMID: 34399812Free PMC Article
Basch E, Becker C, Rogak LJ, Schrag D, Reeve BB, Spears P, Smith ML, Gounder MM, Mahoney MR, Schwartz GK, Bennett AV, Mendoza TR, Cleeland CS, Sloan JA, Bruner DW, Schwab G, Atkinson TM, Thanarajasingam G, Bertagnolli MM, Dueck AC
Clin Trials 2021 Feb;18(1):104-114. Epub 2020 Dec 1 doi: 10.1177/1740774520975120. PMID: 33258687Free PMC Article
Kluetz PG, Chingos DT, Basch EM, Mitchell SA
Am Soc Clin Oncol Educ Book 2016;35:67-73. doi: 10.1200/EDBK_159514. PMID: 27249687

Recent clinical studies

Etiology

Basch E, Dueck AC, Mitchell SA, Mamon H, Weiser M, Saltz L, Gollub M, Rogak L, Ginos B, Mazza GL, Colgrove B, Chang G, Minasian L, Denicoff A, Thanarajasingam G, Musher B, George T, Venook A, Farma J, O'Reilly E, Meyerhardt JA, Shi Q, Schrag D
J Clin Oncol 2023 Jul 20;41(21):3724-3734. Epub 2023 Jun 4 doi: 10.1200/JCO.23.00903. PMID: 37270691Free PMC Article
Wise-Draper TM, Gulati S, Palackdharry S, Hinrichs BH, Worden FP, Old MO, Dunlap NE, Kaczmar JM, Patil Y, Riaz MK, Tang A, Mark J, Zender C, Gillenwater AM, Bell D, Kurtzweil N, Mathews M, Allen CL, Mierzwa ML, Casper K, Jandarov R, Medvedovic M, Lee JJ, Harun N, Takiar V, Gillison M
Clin Cancer Res 2022 Apr 1;28(7):1345-1352. doi: 10.1158/1078-0432.CCR-21-3351. PMID: 35338369Free PMC Article
Gazzah A, Bedard PL, Hierro C, Kang YK, Abdul Razak A, Ryu MH, Demers B, Fagniez N, Henry C, Hospitel M, Soria JC, Tabernero J
Ann Oncol 2022 Apr;33(4):416-425. Epub 2022 Jan 10 doi: 10.1016/j.annonc.2021.12.012. PMID: 35026412
Han MA, Maisch P, Jung JH, Hwang JE, Narayan V, Cleves A, Hwang EC, Dahm P
Cochrane Database Syst Rev 2021 Jun 14;6(6):CD009294. doi: 10.1002/14651858.CD009294.pub3. PMID: 34125951Free PMC Article
Hofman MS, Violet J, Hicks RJ, Ferdinandus J, Thang SP, Akhurst T, Iravani A, Kong G, Ravi Kumar A, Murphy DG, Eu P, Jackson P, Scalzo M, Williams SG, Sandhu S
Lancet Oncol 2018 Jun;19(6):825-833. Epub 2018 May 8 doi: 10.1016/S1470-2045(18)30198-0. PMID: 29752180

Diagnosis

Roth P, Gorlia T, Reijneveld JC, de Vos F, Idbaih A, Frenel JS, Le Rhun E, Sepulveda JM, Perry J, Masucci GL, Freres P, Hirte H, Seidel C, Walenkamp A, Lukacova S, Meijnders P, Blais A, Ducray F, Verschaeve V, Nicholas G, Balana C, Bota DA, Preusser M, Nuyens S, Dhermain F, van den Bent M, O'Callaghan CJ, Vanlancker M, Mason W, Weller M
Neuro Oncol 2024 Sep 5;26(9):1670-1682. doi: 10.1093/neuonc/noae053. PMID: 38502052Free PMC Article
Verdegaal EME, Santegoets SJ, Welters MJP, de Bruin L, Visser M, van der Minne CE, de Kok PM, Loof NM, Boekestijn S, Roozen I, Westra IM, Meij P, Van der Burg SH, Kroep JR
J Immunother Cancer 2023 Nov;11(11) doi: 10.1136/jitc-2023-007697. PMID: 37949617Free PMC Article
Pérez-Alfonso KE, Sánchez-Martínez V
Semin Oncol Nurs 2021 Apr;37(2):151145. Epub 2021 Mar 26 doi: 10.1016/j.soncn.2021.151145. PMID: 33773879
Basch E, Becker C, Rogak LJ, Schrag D, Reeve BB, Spears P, Smith ML, Gounder MM, Mahoney MR, Schwartz GK, Bennett AV, Mendoza TR, Cleeland CS, Sloan JA, Bruner DW, Schwab G, Atkinson TM, Thanarajasingam G, Bertagnolli MM, Dueck AC
Clin Trials 2021 Feb;18(1):104-114. Epub 2020 Dec 1 doi: 10.1177/1740774520975120. PMID: 33258687Free PMC Article
Cereda E, Turri A, Klersy C, Cappello S, Ferrari A, Filippi AR, Brugnatelli S, Caraccia M, Chiellino S, Borioli V, Monaco T, Stella GM, Arcaini L, Benazzo M, Grugnetti G, Pedrazzoli P, Caccialanza R
Cancer Med 2019 Nov;8(16):6923-6932. Epub 2019 Sep 30 doi: 10.1002/cam4.2517. PMID: 31568698Free PMC Article

Therapy

Basch E, Dueck AC, Mitchell SA, Mamon H, Weiser M, Saltz L, Gollub M, Rogak L, Ginos B, Mazza GL, Colgrove B, Chang G, Minasian L, Denicoff A, Thanarajasingam G, Musher B, George T, Venook A, Farma J, O'Reilly E, Meyerhardt JA, Shi Q, Schrag D
J Clin Oncol 2023 Jul 20;41(21):3724-3734. Epub 2023 Jun 4 doi: 10.1200/JCO.23.00903. PMID: 37270691Free PMC Article
Wise-Draper TM, Gulati S, Palackdharry S, Hinrichs BH, Worden FP, Old MO, Dunlap NE, Kaczmar JM, Patil Y, Riaz MK, Tang A, Mark J, Zender C, Gillenwater AM, Bell D, Kurtzweil N, Mathews M, Allen CL, Mierzwa ML, Casper K, Jandarov R, Medvedovic M, Lee JJ, Harun N, Takiar V, Gillison M
Clin Cancer Res 2022 Apr 1;28(7):1345-1352. doi: 10.1158/1078-0432.CCR-21-3351. PMID: 35338369Free PMC Article
Gazzah A, Bedard PL, Hierro C, Kang YK, Abdul Razak A, Ryu MH, Demers B, Fagniez N, Henry C, Hospitel M, Soria JC, Tabernero J
Ann Oncol 2022 Apr;33(4):416-425. Epub 2022 Jan 10 doi: 10.1016/j.annonc.2021.12.012. PMID: 35026412
Han MA, Maisch P, Jung JH, Hwang JE, Narayan V, Cleves A, Hwang EC, Dahm P
Cochrane Database Syst Rev 2021 Jun 14;6(6):CD009294. doi: 10.1002/14651858.CD009294.pub3. PMID: 34125951Free PMC Article
Hofman MS, Violet J, Hicks RJ, Ferdinandus J, Thang SP, Akhurst T, Iravani A, Kong G, Ravi Kumar A, Murphy DG, Eu P, Jackson P, Scalzo M, Williams SG, Sandhu S
Lancet Oncol 2018 Jun;19(6):825-833. Epub 2018 May 8 doi: 10.1016/S1470-2045(18)30198-0. PMID: 29752180

Prognosis

Roth P, Gorlia T, Reijneveld JC, de Vos F, Idbaih A, Frenel JS, Le Rhun E, Sepulveda JM, Perry J, Masucci GL, Freres P, Hirte H, Seidel C, Walenkamp A, Lukacova S, Meijnders P, Blais A, Ducray F, Verschaeve V, Nicholas G, Balana C, Bota DA, Preusser M, Nuyens S, Dhermain F, van den Bent M, O'Callaghan CJ, Vanlancker M, Mason W, Weller M
Neuro Oncol 2024 Sep 5;26(9):1670-1682. doi: 10.1093/neuonc/noae053. PMID: 38502052Free PMC Article
Rejeski K, Wang Y, Hansen DK, Iacoboni G, Bachy E, Bansal R, Penack O, Müller F, Bethge W, Munoz J, Mohty R, Bücklein VL, Barba P, Locke FL, Lin Y, Jain MD, Subklewe M
Blood Adv 2024 Apr 23;8(8):1857-1868. doi: 10.1182/bloodadvances.2023011767. PMID: 38181508Free PMC Article
Verdegaal EME, Santegoets SJ, Welters MJP, de Bruin L, Visser M, van der Minne CE, de Kok PM, Loof NM, Boekestijn S, Roozen I, Westra IM, Meij P, Van der Burg SH, Kroep JR
J Immunother Cancer 2023 Nov;11(11) doi: 10.1136/jitc-2023-007697. PMID: 37949617Free PMC Article
Fulgenzi CAM, Cheon J, D'Alessio A, Nishida N, Ang C, Marron TU, Wu L, Saeed A, Wietharn B, Cammarota A, Pressiani T, Personeni N, Pinter M, Scheiner B, Balcar L, Napolitano A, Huang YH, Phen S, Naqash AR, Vivaldi C, Salani F, Masi G, Bettinger D, Vogel A, Schönlein M, von Felden J, Schulze K, Wege H, Galle PR, Kudo M, Rimassa L, Singal AG, Sharma R, Cortellini A, Gaillard VE, Chon HJ, Pinato DJ
Eur J Cancer 2022 Nov;175:204-213. Epub 2022 Sep 20 doi: 10.1016/j.ejca.2022.08.024. PMID: 36148739
Han MA, Maisch P, Jung JH, Hwang JE, Narayan V, Cleves A, Hwang EC, Dahm P
Cochrane Database Syst Rev 2021 Jun 14;6(6):CD009294. doi: 10.1002/14651858.CD009294.pub3. PMID: 34125951Free PMC Article

Clinical prediction guides

Fulgenzi CAM, Cheon J, D'Alessio A, Nishida N, Ang C, Marron TU, Wu L, Saeed A, Wietharn B, Cammarota A, Pressiani T, Personeni N, Pinter M, Scheiner B, Balcar L, Napolitano A, Huang YH, Phen S, Naqash AR, Vivaldi C, Salani F, Masi G, Bettinger D, Vogel A, Schönlein M, von Felden J, Schulze K, Wege H, Galle PR, Kudo M, Rimassa L, Singal AG, Sharma R, Cortellini A, Gaillard VE, Chon HJ, Pinato DJ
Eur J Cancer 2022 Nov;175:204-213. Epub 2022 Sep 20 doi: 10.1016/j.ejca.2022.08.024. PMID: 36148739
Ghilardi G, Chong EA, Svoboda J, Wohlfarth P, Nasta SD, Williamson S, Landsburg JD, Gerson JN, Barta SK, Pajarillo R, Myers J, Chen AI, Schachter L, Yelton R, Ballard HJ, Hodges Dwinal A, Gier S, Victoriano D, Weber E, Napier E, Garfall A, Porter DL, Jäger U, Maziarz RT, Ruella M, Schuster SJ
Ann Oncol 2022 Sep;33(9):916-928. Epub 2022 Jun 9 doi: 10.1016/j.annonc.2022.05.521. PMID: 35690221Free PMC Article
Peters S, Pujol JL, Dafni U, Dómine M, Popat S, Reck M, Andrade J, Becker A, Moro-Sibilot D, Curioni-Fontecedro A, Molinier O, Nackaerts K, Insa Mollá A, Gervais R, López Vivanco G, Madelaine J, Mazieres J, Faehling M, Griesinger F, Majem M, González Larriba JL, Provencio Pulla M, Vervita K, Roschitzki-Voser H, Ruepp B, Mitchell P, Stahel RA, Le Pechoux C, De Ruysscher D; ETOP/IFCT 4-12 STIMULI Collaborators
Ann Oncol 2022 Jan;33(1):67-79. Epub 2021 Sep 23 doi: 10.1016/j.annonc.2021.09.011. PMID: 34562610
Baggi A, Quaglino P, Rubatto M, Depenni R, Guida M, Ascierto PA, Trojaniello C, Queirolo P, Saponara M, Peris K, Spagnolo F, Bianchi L, De Galitiis F, Potenza MC, Proietti I, Marconcini R, Botticelli A, Barbieri V, Licitra L, Alfieri S, Ficorella C, Cortellini A, Fargnoli MC, Troiani T, Tondulli L, Bossi P
Eur J Cancer 2021 Nov;157:250-258. Epub 2021 Sep 15 doi: 10.1016/j.ejca.2021.08.018. PMID: 34536948
Hofman MS, Violet J, Hicks RJ, Ferdinandus J, Thang SP, Akhurst T, Iravani A, Kong G, Ravi Kumar A, Murphy DG, Eu P, Jackson P, Scalzo M, Williams SG, Sandhu S
Lancet Oncol 2018 Jun;19(6):825-833. Epub 2018 May 8 doi: 10.1016/S1470-2045(18)30198-0. PMID: 29752180

Recent systematic reviews

Kalbfell R, Cohen-Cutler S, Grisham E, Bereitschaft C, Borst AJ, Green AM, Willis DN, Yaeger L, Blatt J, Sisk BA
Pediatr Blood Cancer 2024 Jan;71(1):e30758. Epub 2023 Nov 6 doi: 10.1002/pbc.30758. PMID: 37933207
David R, Buckby A, Kahokehr AA, Lee J, Watson DI, Leung J, O'Callaghan ME
Prostate Cancer Prostatic Dis 2023 Mar;26(1):8-15. Epub 2022 Mar 8 doi: 10.1038/s41391-022-00520-x. PMID: 35260794Free PMC Article
Wolff JE, Wolff BJ, Thielen MM, Hauch H
Anticancer Res 2022 Jun;42(6):2805-2812. doi: 10.21873/anticanres.15761. PMID: 35641292
Han MA, Maisch P, Jung JH, Hwang JE, Narayan V, Cleves A, Hwang EC, Dahm P
Cochrane Database Syst Rev 2021 Jun 14;6(6):CD009294. doi: 10.1002/14651858.CD009294.pub3. PMID: 34125951Free PMC Article
Pérez-Alfonso KE, Sánchez-Martínez V
Semin Oncol Nurs 2021 Apr;37(2):151145. Epub 2021 Mar 26 doi: 10.1016/j.soncn.2021.151145. PMID: 33773879

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