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Grade 1 Skin Ulceration, CTCAE

MedGen UID:
1634262
•Concept ID:
C4688524
•
Finding

Definition

Combined area of ulcers <1 cm; nonblanchable erythema of intact skin with associated warmth or edema [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 1 Skin Ulceration, CTCAE

Professional guidelines

PubMed

Clinical Utility of Bland Embolization Using Microspheres for Painful Malignant Musculoskeletal Tumors.
Taniguchi J, Takaki H, Kodama H, Kawaguchi T, Takahagi M, Ogasawara A, Kako Y, Kobayashi K, Minami T, Futani H, Yamakado K
In Vivo 2023 Jul-Aug;37(4):1816-1821. doi: 10.21873/invivo.13272. PMID: 37369519Free PMC Article

Recent clinical studies

Etiology

Clinical Utility of Bland Embolization Using Microspheres for Painful Malignant Musculoskeletal Tumors.
Taniguchi J, Takaki H, Kodama H, Kawaguchi T, Takahagi M, Ogasawara A, Kako Y, Kobayashi K, Minami T, Futani H, Yamakado K
In Vivo 2023 Jul-Aug;37(4):1816-1821. doi: 10.21873/invivo.13272. PMID: 37369519Free PMC Article
Hypofractionated, 3-week, preoperative radiotherapy for patients with soft tissue sarcomas (HYPORT-STS): a single-centre, open-label, single-arm, phase 2 trial.
Guadagnolo BA, Bassett RL, Mitra D, Farooqi A, Hempel C, Dorber C, Willis T, Wang WL, Ratan R, Somaiah N, Benjamin RS, Torres KE, Hunt KK, Scally CP, Keung EZ, Satcher RL, Bird JE, Lin PP, Moon BS, Lewis VO, Roland CL, Bishop AJ
Lancet Oncol 2022 Dec;23(12):1547-1557. Epub 2022 Nov 4 doi: 10.1016/S1470-2045(22)00638-6. PMID: 36343656Free PMC Article
Treprostinil Hydrogel Iontophoresis in Systemic Sclerosis-Related Digital Skin Ulcers: A Safety Study.
Guigui A, Mazet R, Blaise S, Cracowski C, Beau-Guillaumot M, Kotzki S, Roustit M, Cracowski JL
J Clin Pharmacol 2020 Jun;60(6):758-767. Epub 2020 Feb 20 doi: 10.1002/jcph.1574. PMID: 32080862
Electrochemotherapy for advanced cutaneous angiosarcoma: A European register-based cohort study from the International Network for Sharing Practices of electrochemotherapy (InspECT).
Campana LG, Kis E, Bottyán K, Orlando A, de Terlizzi F, Mitsala G, Careri R, Curatolo P, Snoj M, Sersa G, Valpione S, Quaglino P, Mowatt D, Brizio M, Schepler H
Int J Surg 2019 Dec;72:34-42. Epub 2019 Oct 13 doi: 10.1016/j.ijsu.2019.10.013. PMID: 31618680
Excellent local control and survival after postoperative or definitive radiation therapy for sarcomas of the head and neck.
Andrä C, Rauch J, Li M, Ganswindt U, Belka C, Saleh-Ebrahimi L, Ballhausen H, Nachbichler SB, Roeder F
Radiat Oncol 2015 Jul 10;10:140. doi: 10.1186/s13014-015-0449-x. PMID: 26156022Free PMC Article

Therapy

Hypofractionated, 3-week, preoperative radiotherapy for patients with soft tissue sarcomas (HYPORT-STS): a single-centre, open-label, single-arm, phase 2 trial.
Guadagnolo BA, Bassett RL, Mitra D, Farooqi A, Hempel C, Dorber C, Willis T, Wang WL, Ratan R, Somaiah N, Benjamin RS, Torres KE, Hunt KK, Scally CP, Keung EZ, Satcher RL, Bird JE, Lin PP, Moon BS, Lewis VO, Roland CL, Bishop AJ
Lancet Oncol 2022 Dec;23(12):1547-1557. Epub 2022 Nov 4 doi: 10.1016/S1470-2045(22)00638-6. PMID: 36343656Free PMC Article
Treprostinil Hydrogel Iontophoresis in Systemic Sclerosis-Related Digital Skin Ulcers: A Safety Study.
Guigui A, Mazet R, Blaise S, Cracowski C, Beau-Guillaumot M, Kotzki S, Roustit M, Cracowski JL
J Clin Pharmacol 2020 Jun;60(6):758-767. Epub 2020 Feb 20 doi: 10.1002/jcph.1574. PMID: 32080862
Electrochemotherapy for advanced cutaneous angiosarcoma: A European register-based cohort study from the International Network for Sharing Practices of electrochemotherapy (InspECT).
Campana LG, Kis E, Bottyán K, Orlando A, de Terlizzi F, Mitsala G, Careri R, Curatolo P, Snoj M, Sersa G, Valpione S, Quaglino P, Mowatt D, Brizio M, Schepler H
Int J Surg 2019 Dec;72:34-42. Epub 2019 Oct 13 doi: 10.1016/j.ijsu.2019.10.013. PMID: 31618680
Excellent local control and survival after postoperative or definitive radiation therapy for sarcomas of the head and neck.
Andrä C, Rauch J, Li M, Ganswindt U, Belka C, Saleh-Ebrahimi L, Ballhausen H, Nachbichler SB, Roeder F
Radiat Oncol 2015 Jul 10;10:140. doi: 10.1186/s13014-015-0449-x. PMID: 26156022Free PMC Article
Phase I clinical trial of a peptide vaccine combined with tegafur-uracil plus leucovorin for treatment of advanced or recurrent colorectal cancer.
Matsushita N, Aruga A, Inoue Y, Kotera Y, Takeda K, Yamamoto M
Oncol Rep 2013 Mar;29(3):951-9. Epub 2013 Jan 10 doi: 10.3892/or.2013.2231. PMID: 23314271

Prognosis

Electrochemotherapy for advanced cutaneous angiosarcoma: A European register-based cohort study from the International Network for Sharing Practices of electrochemotherapy (InspECT).
Campana LG, Kis E, Bottyán K, Orlando A, de Terlizzi F, Mitsala G, Careri R, Curatolo P, Snoj M, Sersa G, Valpione S, Quaglino P, Mowatt D, Brizio M, Schepler H
Int J Surg 2019 Dec;72:34-42. Epub 2019 Oct 13 doi: 10.1016/j.ijsu.2019.10.013. PMID: 31618680
Excellent local control and survival after postoperative or definitive radiation therapy for sarcomas of the head and neck.
Andrä C, Rauch J, Li M, Ganswindt U, Belka C, Saleh-Ebrahimi L, Ballhausen H, Nachbichler SB, Roeder F
Radiat Oncol 2015 Jul 10;10:140. doi: 10.1186/s13014-015-0449-x. PMID: 26156022Free PMC Article
Phase I clinical trial of a peptide vaccine combined with tegafur-uracil plus leucovorin for treatment of advanced or recurrent colorectal cancer.
Matsushita N, Aruga A, Inoue Y, Kotera Y, Takeda K, Yamamoto M
Oncol Rep 2013 Mar;29(3):951-9. Epub 2013 Jan 10 doi: 10.3892/or.2013.2231. PMID: 23314271

Clinical prediction guides

Clinical Utility of Bland Embolization Using Microspheres for Painful Malignant Musculoskeletal Tumors.
Taniguchi J, Takaki H, Kodama H, Kawaguchi T, Takahagi M, Ogasawara A, Kako Y, Kobayashi K, Minami T, Futani H, Yamakado K
In Vivo 2023 Jul-Aug;37(4):1816-1821. doi: 10.21873/invivo.13272. PMID: 37369519Free PMC Article
Treprostinil Hydrogel Iontophoresis in Systemic Sclerosis-Related Digital Skin Ulcers: A Safety Study.
Guigui A, Mazet R, Blaise S, Cracowski C, Beau-Guillaumot M, Kotzki S, Roustit M, Cracowski JL
J Clin Pharmacol 2020 Jun;60(6):758-767. Epub 2020 Feb 20 doi: 10.1002/jcph.1574. PMID: 32080862
Electrochemotherapy for advanced cutaneous angiosarcoma: A European register-based cohort study from the International Network for Sharing Practices of electrochemotherapy (InspECT).
Campana LG, Kis E, Bottyán K, Orlando A, de Terlizzi F, Mitsala G, Careri R, Curatolo P, Snoj M, Sersa G, Valpione S, Quaglino P, Mowatt D, Brizio M, Schepler H
Int J Surg 2019 Dec;72:34-42. Epub 2019 Oct 13 doi: 10.1016/j.ijsu.2019.10.013. PMID: 31618680
Excellent local control and survival after postoperative or definitive radiation therapy for sarcomas of the head and neck.
Andrä C, Rauch J, Li M, Ganswindt U, Belka C, Saleh-Ebrahimi L, Ballhausen H, Nachbichler SB, Roeder F
Radiat Oncol 2015 Jul 10;10:140. doi: 10.1186/s13014-015-0449-x. PMID: 26156022Free PMC Article
Phase I clinical trial of a peptide vaccine combined with tegafur-uracil plus leucovorin for treatment of advanced or recurrent colorectal cancer.
Matsushita N, Aruga A, Inoue Y, Kotera Y, Takeda K, Yamamoto M
Oncol Rep 2013 Mar;29(3):951-9. Epub 2013 Jan 10 doi: 10.3892/or.2013.2231. PMID: 23314271

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