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Grade 3 Anal Hemorrhage, CTCAE

MedGen UID:
1638058
•Concept ID:
C4686062
•
Finding

Definition

Transfusion indicated; invasive intervention indicated; hospitalization [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 3 Anal Hemorrhage, CTCAE

Professional guidelines

PubMed

Sarcopenia and dosimetric parameters in relation to treatment-related leukopenia and survival in anal cancer.
Nilsson MP, Johnsson A, Scherman J
Radiat Oncol 2021 Aug 16;16(1):152. doi: 10.1186/s13014-021-01876-5. PMID: 34399812Free PMC Article

Recent clinical studies

Etiology

Hematologic Toxicity Comparison of Intensity Modulated Proton Therapy and Intensity Modulated Radiation Therapy in Anal Cancer Patients.
Nelson B, Tadesse DG, Sudhoff M, Wang K, Meier T, Mascia A, Kharofa J
Am J Clin Oncol 2022 Jun 1;45(6):264-267. Epub 2022 May 2 doi: 10.1097/COC.0000000000000916. PMID: 35588226
Dosimetric and Clinical Predictors for Acute and Late Gastrointestinal Toxicity Following Chemoradiotherapy of Locally Advanced Anal Cancer.
Nilsson MP, Gunnlaugsson A, Johnsson A, Scherman J
Clin Oncol (R Coll Radiol) 2022 Jan;34(1):e35-e44. Epub 2021 Sep 28 doi: 10.1016/j.clon.2021.09.011. PMID: 34598844
Sarcopenia and dosimetric parameters in relation to treatment-related leukopenia and survival in anal cancer.
Nilsson MP, Johnsson A, Scherman J
Radiat Oncol 2021 Aug 16;16(1):152. doi: 10.1186/s13014-021-01876-5. PMID: 34399812Free PMC Article
Irreversible Electroporation to Treat Malignant Tumor Recurrences Within the Pelvic Cavity: A Case Series.
Vroomen LGPH, Scheffer HJ, Melenhorst MCAM, van Grieken N, van den Tol MP, Meijerink MR
Cardiovasc Intervent Radiol 2017 Oct;40(10):1631-1640. Epub 2017 May 3 doi: 10.1007/s00270-017-1657-6. PMID: 28470395Free PMC Article

Diagnosis

Sarcopenia and dosimetric parameters in relation to treatment-related leukopenia and survival in anal cancer.
Nilsson MP, Johnsson A, Scherman J
Radiat Oncol 2021 Aug 16;16(1):152. doi: 10.1186/s13014-021-01876-5. PMID: 34399812Free PMC Article

Therapy

Feasibility Trial of Intensity Modulated Proton Therapy to Reduce Toxicity in Anal Cancer Patients.
Nelson B, Meier T, Zhang Y, Wang K, Mascia AE, Paquette I, Thompson E, Rafferty J, Snyder J, Olowokure O, Sohal D, Kharofa J
Am J Clin Oncol 2023 Jul 1;46(7):293-299. Epub 2023 Apr 24 doi: 10.1097/COC.0000000000001007. PMID: 37088904
Hematologic Toxicity Comparison of Intensity Modulated Proton Therapy and Intensity Modulated Radiation Therapy in Anal Cancer Patients.
Nelson B, Tadesse DG, Sudhoff M, Wang K, Meier T, Mascia A, Kharofa J
Am J Clin Oncol 2022 Jun 1;45(6):264-267. Epub 2022 May 2 doi: 10.1097/COC.0000000000000916. PMID: 35588226
Dosimetric and Clinical Predictors for Acute and Late Gastrointestinal Toxicity Following Chemoradiotherapy of Locally Advanced Anal Cancer.
Nilsson MP, Gunnlaugsson A, Johnsson A, Scherman J
Clin Oncol (R Coll Radiol) 2022 Jan;34(1):e35-e44. Epub 2021 Sep 28 doi: 10.1016/j.clon.2021.09.011. PMID: 34598844
Sarcopenia and dosimetric parameters in relation to treatment-related leukopenia and survival in anal cancer.
Nilsson MP, Johnsson A, Scherman J
Radiat Oncol 2021 Aug 16;16(1):152. doi: 10.1186/s13014-021-01876-5. PMID: 34399812Free PMC Article

Prognosis

Dosimetric and Clinical Predictors for Acute and Late Gastrointestinal Toxicity Following Chemoradiotherapy of Locally Advanced Anal Cancer.
Nilsson MP, Gunnlaugsson A, Johnsson A, Scherman J
Clin Oncol (R Coll Radiol) 2022 Jan;34(1):e35-e44. Epub 2021 Sep 28 doi: 10.1016/j.clon.2021.09.011. PMID: 34598844
Sarcopenia and dosimetric parameters in relation to treatment-related leukopenia and survival in anal cancer.
Nilsson MP, Johnsson A, Scherman J
Radiat Oncol 2021 Aug 16;16(1):152. doi: 10.1186/s13014-021-01876-5. PMID: 34399812Free PMC Article
Irreversible Electroporation to Treat Malignant Tumor Recurrences Within the Pelvic Cavity: A Case Series.
Vroomen LGPH, Scheffer HJ, Melenhorst MCAM, van Grieken N, van den Tol MP, Meijerink MR
Cardiovasc Intervent Radiol 2017 Oct;40(10):1631-1640. Epub 2017 May 3 doi: 10.1007/s00270-017-1657-6. PMID: 28470395Free PMC Article

Clinical prediction guides

Feasibility Trial of Intensity Modulated Proton Therapy to Reduce Toxicity in Anal Cancer Patients.
Nelson B, Meier T, Zhang Y, Wang K, Mascia AE, Paquette I, Thompson E, Rafferty J, Snyder J, Olowokure O, Sohal D, Kharofa J
Am J Clin Oncol 2023 Jul 1;46(7):293-299. Epub 2023 Apr 24 doi: 10.1097/COC.0000000000001007. PMID: 37088904
Dosimetric and Clinical Predictors for Acute and Late Gastrointestinal Toxicity Following Chemoradiotherapy of Locally Advanced Anal Cancer.
Nilsson MP, Gunnlaugsson A, Johnsson A, Scherman J
Clin Oncol (R Coll Radiol) 2022 Jan;34(1):e35-e44. Epub 2021 Sep 28 doi: 10.1016/j.clon.2021.09.011. PMID: 34598844
Sarcopenia and dosimetric parameters in relation to treatment-related leukopenia and survival in anal cancer.
Nilsson MP, Johnsson A, Scherman J
Radiat Oncol 2021 Aug 16;16(1):152. doi: 10.1186/s13014-021-01876-5. PMID: 34399812Free PMC Article
Irreversible Electroporation to Treat Malignant Tumor Recurrences Within the Pelvic Cavity: A Case Series.
Vroomen LGPH, Scheffer HJ, Melenhorst MCAM, van Grieken N, van den Tol MP, Meijerink MR
Cardiovasc Intervent Radiol 2017 Oct;40(10):1631-1640. Epub 2017 May 3 doi: 10.1007/s00270-017-1657-6. PMID: 28470395Free PMC Article

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