U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal HDL cholesterol concentration

MedGen UID:
1640068
Concept ID:
C4703600
Finding
HPO: HP:0031888

Definition

Any deviation from the normal concentration of high-density lipoprotein cholesterol (HDL) in the blood. [from HPO]

Professional guidelines

PubMed

Nordestgaard BG, Langsted A, Mora S, Kolovou G, Baum H, Bruckert E, Watts GF, Sypniewska G, Wiklund O, Borén J, Chapman MJ, Cobbaert C, Descamps OS, von Eckardstein A, Kamstrup PR, Pulkki K, Kronenberg F, Remaley AT, Rifai N, Ros E, Langlois M; European Atherosclerosis Society (EAS) and the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Joint Consensus Initiative
Clin Chem 2016 Jul;62(7):930-46. Epub 2016 May 27 doi: 10.1373/clinchem.2016.258897. PMID: 27235445
Nordestgaard BG, Langsted A, Mora S, Kolovou G, Baum H, Bruckert E, Watts GF, Sypniewska G, Wiklund O, Borén J, Chapman MJ, Cobbaert C, Descamps OS, von Eckardstein A, Kamstrup PR, Pulkki K, Kronenberg F, Remaley AT, Rifai N, Ros E, Langlois M; European Atherosclerosis Society (EAS) and the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) joint consensus initiative
Eur Heart J 2016 Jul 1;37(25):1944-58. Epub 2016 Apr 26 doi: 10.1093/eurheartj/ehw152. PMID: 27122601Free PMC Article
Rosenson RS
Expert Rev Cardiovasc Ther 2008 Nov;6(10):1319-30. doi: 10.1586/14779072.6.10.1319. PMID: 19018684

Recent clinical studies

Etiology

Martagon AJ, Zubirán R, González-Arellanes R, Praget-Bracamontes S, Rivera-Alcántara JA, Aguilar-Salinas CA
Atherosclerosis 2024 Jul;394:117213. Epub 2023 Aug 3 doi: 10.1016/j.atherosclerosis.2023.117213. PMID: 37580206
Mosteoru S, Gaiţă L, Gaiţă D
Curr Atheroscler Rep 2023 Sep;25(9):613-617. Epub 2023 Aug 7 doi: 10.1007/s11883-023-01133-y. PMID: 37548846
Hirano T
J Atheroscler Thromb 2018 Sep 1;25(9):771-782. Epub 2018 Jul 12 doi: 10.5551/jat.RV17023. PMID: 29998913Free PMC Article
Ganjali S, Dallinga-Thie GM, Simental-Mendía LE, Banach M, Pirro M, Sahebkar A
Atherosclerosis 2017 Dec;267:99-109. Epub 2017 Oct 21 doi: 10.1016/j.atherosclerosis.2017.10.018. PMID: 29102899
Chang TI, Streja E, Moradi H
Curr Opin Endocrinol Diabetes Obes 2017 Apr;24(2):140-147. doi: 10.1097/MED.0000000000000318. PMID: 28099207

Diagnosis

Martagon AJ, Zubirán R, González-Arellanes R, Praget-Bracamontes S, Rivera-Alcántara JA, Aguilar-Salinas CA
Atherosclerosis 2024 Jul;394:117213. Epub 2023 Aug 3 doi: 10.1016/j.atherosclerosis.2023.117213. PMID: 37580206
Millán-de-Meer M, Luque-Ramírez M, Nattero-Chávez L, Escobar-Morreale HF
Hum Reprod Update 2023 Nov 2;29(6):741-772. doi: 10.1093/humupd/dmad015. PMID: 37353908
Desmond MA, Sobiecki JG, Jaworski M, Płudowski P, Antoniewicz J, Shirley MK, Eaton S, Książyk J, Cortina-Borja M, De Stavola B, Fewtrell M, Wells JCK
Am J Clin Nutr 2021 Jun 1;113(6):1565-1577. doi: 10.1093/ajcn/nqaa445. PMID: 33740036Free PMC Article
Chang TI, Streja E, Moradi H
Curr Opin Endocrinol Diabetes Obes 2017 Apr;24(2):140-147. doi: 10.1097/MED.0000000000000318. PMID: 28099207
DiNicolantonio JJ, Lucan SC, O'Keefe JH
Prog Cardiovasc Dis 2016 Mar-Apr;58(5):464-72. Epub 2015 Nov 14 doi: 10.1016/j.pcad.2015.11.006. PMID: 26586275Free PMC Article

Therapy

Martagon AJ, Zubirán R, González-Arellanes R, Praget-Bracamontes S, Rivera-Alcántara JA, Aguilar-Salinas CA
Atherosclerosis 2024 Jul;394:117213. Epub 2023 Aug 3 doi: 10.1016/j.atherosclerosis.2023.117213. PMID: 37580206
Millán-de-Meer M, Luque-Ramírez M, Nattero-Chávez L, Escobar-Morreale HF
Hum Reprod Update 2023 Nov 2;29(6):741-772. doi: 10.1093/humupd/dmad015. PMID: 37353908
Nordestgaard BG, Langsted A, Mora S, Kolovou G, Baum H, Bruckert E, Watts GF, Sypniewska G, Wiklund O, Borén J, Chapman MJ, Cobbaert C, Descamps OS, von Eckardstein A, Kamstrup PR, Pulkki K, Kronenberg F, Remaley AT, Rifai N, Ros E, Langlois M; European Atherosclerosis Society (EAS) and the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) joint consensus initiative
Eur Heart J 2016 Jul 1;37(25):1944-58. Epub 2016 Apr 26 doi: 10.1093/eurheartj/ehw152. PMID: 27122601Free PMC Article
DiNicolantonio JJ, Lucan SC, O'Keefe JH
Prog Cardiovasc Dis 2016 Mar-Apr;58(5):464-72. Epub 2015 Nov 14 doi: 10.1016/j.pcad.2015.11.006. PMID: 26586275Free PMC Article
Betteridge DJ
Diabetes Obes Metab 2000 Mar;2 Suppl 1:S31-6. doi: 10.1046/j.1463-1326.2000.00021.x. PMID: 11225757

Prognosis

Millán-de-Meer M, Luque-Ramírez M, Nattero-Chávez L, Escobar-Morreale HF
Hum Reprod Update 2023 Nov 2;29(6):741-772. doi: 10.1093/humupd/dmad015. PMID: 37353908
Strazzella A, Ossoli A, Calabresi L
Cells 2021 Mar 31;10(4) doi: 10.3390/cells10040764. PMID: 33807271Free PMC Article
Hirano T
J Atheroscler Thromb 2018 Sep 1;25(9):771-782. Epub 2018 Jul 12 doi: 10.5551/jat.RV17023. PMID: 29998913Free PMC Article
Nordestgaard BG, Langsted A, Mora S, Kolovou G, Baum H, Bruckert E, Watts GF, Sypniewska G, Wiklund O, Borén J, Chapman MJ, Cobbaert C, Descamps OS, von Eckardstein A, Kamstrup PR, Pulkki K, Kronenberg F, Remaley AT, Rifai N, Ros E, Langlois M; European Atherosclerosis Society (EAS) and the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) joint consensus initiative
Eur Heart J 2016 Jul 1;37(25):1944-58. Epub 2016 Apr 26 doi: 10.1093/eurheartj/ehw152. PMID: 27122601Free PMC Article
DiNicolantonio JJ, Lucan SC, O'Keefe JH
Prog Cardiovasc Dis 2016 Mar-Apr;58(5):464-72. Epub 2015 Nov 14 doi: 10.1016/j.pcad.2015.11.006. PMID: 26586275Free PMC Article

Clinical prediction guides

Geng TT, Chen JX, Lu Q, Wang PL, Xia PF, Zhu K, Li Y, Guo KQ, Yang K, Liao YF, Zhou YF, Liu G, Pan A
Am J Kidney Dis 2024 Jan;83(1):9-17. Epub 2023 Sep 9 doi: 10.1053/j.ajkd.2023.05.014. PMID: 37678743
Strazzella A, Ossoli A, Calabresi L
Cells 2021 Mar 31;10(4) doi: 10.3390/cells10040764. PMID: 33807271Free PMC Article
Hirano T
J Atheroscler Thromb 2018 Sep 1;25(9):771-782. Epub 2018 Jul 12 doi: 10.5551/jat.RV17023. PMID: 29998913Free PMC Article
Nordestgaard BG, Langsted A, Mora S, Kolovou G, Baum H, Bruckert E, Watts GF, Sypniewska G, Wiklund O, Borén J, Chapman MJ, Cobbaert C, Descamps OS, von Eckardstein A, Kamstrup PR, Pulkki K, Kronenberg F, Remaley AT, Rifai N, Ros E, Langlois M; European Atherosclerosis Society (EAS) and the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) joint consensus initiative
Eur Heart J 2016 Jul 1;37(25):1944-58. Epub 2016 Apr 26 doi: 10.1093/eurheartj/ehw152. PMID: 27122601Free PMC Article
DiNicolantonio JJ, Lucan SC, O'Keefe JH
Prog Cardiovasc Dis 2016 Mar-Apr;58(5):464-72. Epub 2015 Nov 14 doi: 10.1016/j.pcad.2015.11.006. PMID: 26586275Free PMC Article

Recent systematic reviews

Millán-de-Meer M, Luque-Ramírez M, Nattero-Chávez L, Escobar-Morreale HF
Hum Reprod Update 2023 Nov 2;29(6):741-772. doi: 10.1093/humupd/dmad015. PMID: 37353908
Xia W, Xiang S, Gaman MA, Jamilian P, Prabahar K, Du G, Gao D
Phytother Res 2022 Dec;36(12):4398-4408. Epub 2022 Sep 30 doi: 10.1002/ptr.7646. PMID: 36180973
Hasan B, Nayfeh T, Alzuabi M, Wang Z, Kuchkuntla AR, Prokop LJ, Newman CB, Murad MH, Rajjo TI
J Clin Endocrinol Metab 2020 Dec 1;105(12) doi: 10.1210/clinem/dgaa673. PMID: 32954416
Liu F, Prabhakar M, Ju J, Long H, Zhou HW
Eur J Clin Nutr 2017 Jan;71(1):9-20. Epub 2016 Sep 14 doi: 10.1038/ejcn.2016.156. PMID: 27623982
Wild RA, Rizzo M, Clifton S, Carmina E
Fertil Steril 2011 Mar 1;95(3):1073-9.e1-11. Epub 2011 Jan 17 doi: 10.1016/j.fertnstert.2010.12.027. PMID: 21247558

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...