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Grade 1 Blood Bilirubin Increased, CTCAE

MedGen UID:
1641213
•Concept ID:
C4685048
•
Finding

Definition

>ULN-1.5 x ULN if baseline was normal; > 1.0-1.5 x baseline if baseline was abnormal [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 1 Blood Bilirubin Increased, CTCAE

Recent clinical studies

Etiology

Elevated posaconazole trough concentrations are not associated with increased risk for posaconazole toxicity in lung transplant recipients.
Sabatino DC, Lange NW, Salerno DM, Scheffert J
Clin Transplant 2023 Jan;37(1):e14826. Epub 2022 Oct 26 doi: 10.1111/ctr.14826. PMID: 36205935
Rates of laboratory adverse events by course in paediatric leukaemia ascertained with automated electronic health record extraction: a retrospective cohort study from the Children's Oncology Group.
Miller TP, Getz KD, Li Y, Demissei BG, Adamson PC, Alonzo TA, Burrows E, Cao L, Castellino SM, Daves MH, Fisher BT, Gerbing R, Grundmeier RW, Krause EM, Lee J, Lupo PJ, Rabin KR, Ramos M, Scheurer ME, Wilkes JJ, Winestone LE, Hawkins DS, Gramatges MM, Aplenc R
Lancet Haematol 2022 Sep;9(9):e678-e688. Epub 2022 Jul 20 doi: 10.1016/S2352-3026(22)00168-5. PMID: 35870472Free PMC Article
Cytokines and (90)Y-Radioembolization: Relation to Liver Function and Overall Survival.
Seidensticker M, Powerski M, Seidensticker R, Damm R, Mohnike K, Garlipp B, Klopffleisch M, Amthauer H, Ricke J, Pech M
Cardiovasc Intervent Radiol 2017 Aug;40(8):1185-1195. Epub 2017 Mar 10 doi: 10.1007/s00270-017-1622-4. PMID: 28283704

Therapy

Elevated posaconazole trough concentrations are not associated with increased risk for posaconazole toxicity in lung transplant recipients.
Sabatino DC, Lange NW, Salerno DM, Scheffert J
Clin Transplant 2023 Jan;37(1):e14826. Epub 2022 Oct 26 doi: 10.1111/ctr.14826. PMID: 36205935
Rates of laboratory adverse events by course in paediatric leukaemia ascertained with automated electronic health record extraction: a retrospective cohort study from the Children's Oncology Group.
Miller TP, Getz KD, Li Y, Demissei BG, Adamson PC, Alonzo TA, Burrows E, Cao L, Castellino SM, Daves MH, Fisher BT, Gerbing R, Grundmeier RW, Krause EM, Lee J, Lupo PJ, Rabin KR, Ramos M, Scheurer ME, Wilkes JJ, Winestone LE, Hawkins DS, Gramatges MM, Aplenc R
Lancet Haematol 2022 Sep;9(9):e678-e688. Epub 2022 Jul 20 doi: 10.1016/S2352-3026(22)00168-5. PMID: 35870472Free PMC Article
Cytokines and (90)Y-Radioembolization: Relation to Liver Function and Overall Survival.
Seidensticker M, Powerski M, Seidensticker R, Damm R, Mohnike K, Garlipp B, Klopffleisch M, Amthauer H, Ricke J, Pech M
Cardiovasc Intervent Radiol 2017 Aug;40(8):1185-1195. Epub 2017 Mar 10 doi: 10.1007/s00270-017-1622-4. PMID: 28283704

Prognosis

Rates of laboratory adverse events by course in paediatric leukaemia ascertained with automated electronic health record extraction: a retrospective cohort study from the Children's Oncology Group.
Miller TP, Getz KD, Li Y, Demissei BG, Adamson PC, Alonzo TA, Burrows E, Cao L, Castellino SM, Daves MH, Fisher BT, Gerbing R, Grundmeier RW, Krause EM, Lee J, Lupo PJ, Rabin KR, Ramos M, Scheurer ME, Wilkes JJ, Winestone LE, Hawkins DS, Gramatges MM, Aplenc R
Lancet Haematol 2022 Sep;9(9):e678-e688. Epub 2022 Jul 20 doi: 10.1016/S2352-3026(22)00168-5. PMID: 35870472Free PMC Article
Cytokines and (90)Y-Radioembolization: Relation to Liver Function and Overall Survival.
Seidensticker M, Powerski M, Seidensticker R, Damm R, Mohnike K, Garlipp B, Klopffleisch M, Amthauer H, Ricke J, Pech M
Cardiovasc Intervent Radiol 2017 Aug;40(8):1185-1195. Epub 2017 Mar 10 doi: 10.1007/s00270-017-1622-4. PMID: 28283704

Clinical prediction guides

Elevated posaconazole trough concentrations are not associated with increased risk for posaconazole toxicity in lung transplant recipients.
Sabatino DC, Lange NW, Salerno DM, Scheffert J
Clin Transplant 2023 Jan;37(1):e14826. Epub 2022 Oct 26 doi: 10.1111/ctr.14826. PMID: 36205935

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