U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Blood and Lymphatic System Disorders, CTCAE

MedGen UID:
1641996
•Concept ID:
C4553112
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBlood and Lymphatic System Disorders, CTCAE

Professional guidelines

PubMed

Fix low dose venetoclax-azacitidine treatment of unfit acute myeloid leukemia patients.
Miklos E, Oliver TP, Adam K, Eva K, Balazs K, Eszter K, Anett P, Viktoria GK, Jozsef H, Peter R
Eur J Haematol 2024 Aug;113(2):183-189. Epub 2024 Apr 21 doi: 10.1111/ejh.14213. PMID: 38644361
Sarcopenia and dosimetric parameters in relation to treatment-related leukopenia and survival in anal cancer.
Nilsson MP, Johnsson A, Scherman J
Radiat Oncol 2021 Aug 16;16(1):152. doi: 10.1186/s13014-021-01876-5. PMID: 34399812Free PMC Article
Taste disorders following cancer treatment: report of a case series.
Epstein JB, de Andrade E Silva SM, Epstein GL, Leal JHS, Barasch A, Smutzer G
Support Care Cancer 2019 Dec;27(12):4587-4595. Epub 2019 Mar 29 doi: 10.1007/s00520-019-04758-5. PMID: 30927113

Recent clinical studies

Etiology

Applying the EHA/EBMT grading for ICAHT after CAR-T: comparative incidence and association with infections and mortality.
Rejeski K, Wang Y, Hansen DK, Iacoboni G, Bachy E, Bansal R, Penack O, Müller F, Bethge W, Munoz J, Mohty R, Bücklein VL, Barba P, Locke FL, Lin Y, Jain MD, Subklewe M
Blood Adv 2024 Apr 23;8(8):1857-1868. doi: 10.1182/bloodadvances.2023011767. PMID: 38181508Free PMC Article
Phase I non-randomized clinical trial of allogeneic natural killer cells infusion in acute myeloid leukemia patients.
Ahmadvand M, Barough MS, Barkhordar M, Faridfar A, Ghaderi A, Jalaeikhoo H, Rajaienejad M, Majidzadeh K, Ghavamzadeh A, Sarrami-Forooshani R
BMC Cancer 2023 Nov 10;23(1):1090. doi: 10.1186/s12885-023-11610-x. PMID: 37950209Free PMC Article
Organ complications after CD19 CAR T-cell therapy for large B cell lymphoma: a retrospective study from the EBMT transplant complications and lymphoma working party.
Penack O, Peczynski C, Koenecke C, Polge E, Sanderson R, Yakoub-Agha I, Fegueux N, Daskalakis M, Collin M, Dreger P, Kröger N, Schanz U, Bloor A, Ganser A, Besley C, Wulf GG, Novak U, Moiseev I, Schoemans H, Basak GW, Chabannon C, Sureda A, Glass B, Peric Z
Front Immunol 2023;14:1252811. Epub 2023 Sep 27 doi: 10.3389/fimmu.2023.1252811. PMID: 37828980Free PMC Article
Bendamustine is safe and effective for lymphodepletion before tisagenlecleucel in patients with refractory or relapsed large B-cell lymphomas.
Ghilardi G, Chong EA, Svoboda J, Wohlfarth P, Nasta SD, Williamson S, Landsburg JD, Gerson JN, Barta SK, Pajarillo R, Myers J, Chen AI, Schachter L, Yelton R, Ballard HJ, Hodges Dwinal A, Gier S, Victoriano D, Weber E, Napier E, Garfall A, Porter DL, Jäger U, Maziarz RT, Ruella M, Schuster SJ
Ann Oncol 2022 Sep;33(9):916-928. Epub 2022 Jun 9 doi: 10.1016/j.annonc.2022.05.521. PMID: 35690221Free PMC Article
Impact of dose and volume on lymphedema.
Nardone L, Palazzoni G, D'Angelo E, Deodato F, Gambacorta MA, Miccichè F, Morganti AG
Rays 2005 Apr-Jun;30(2):149-55. PMID: 16294908

Diagnosis

Hematologic abnormalities in Aicardi Goutières Syndrome.
Adang LA, Gavazzi F, D'Aiello R, Isaacs D, Bronner N, Arici ZS, Flores Z, Jan A, Scher C, Sherbini O, Behrens EM, Goldbach-Mansky R, Olson TS, Lambert MP, Sullivan KE, Teachey DT, Witmer C, Vanderver A, Shults J
Mol Genet Metab 2022 Aug;136(4):324-329. Epub 2022 Jun 16 doi: 10.1016/j.ymgme.2022.06.003. PMID: 35786528Free PMC Article
Glial injury in neurotoxicity after pediatric CD19-directed chimeric antigen receptor T cell therapy.
Gust J, Finney OC, Li D, Brakke HM, Hicks RM, Futrell RB, Gamble DN, Rawlings-Rhea SD, Khalatbari HK, Ishak GE, Duncan VE, Hevner RF, Jensen MC, Park JR, Gardner RA
Ann Neurol 2019 Jul;86(1):42-54. Epub 2019 May 27 doi: 10.1002/ana.25502. PMID: 31074527Free PMC Article
Acupuncture for Bortezomib-Induced Peripheral Neuropathy: Not Just for Pain.
Zhi WI, Ingram E, Li SQ, Chen P, Piulson L, Bao T
Integr Cancer Ther 2018 Dec;17(4):1079-1086. Epub 2018 Jul 20 doi: 10.1177/1534735418788667. PMID: 30027756Free PMC Article
The Incidence of Ototoxicity in Patients Using Iron Chelators.
Derin S, Azık FM, Topal Y, Topal H, Karakuş V, Çetinkaya PU, Şahan M, Azık TE, Kocabaş CN
J Int Adv Otol 2017 Apr;13(1):136-139. Epub 2016 Nov 23 doi: 10.5152/iao.2016.1852. PMID: 27879229
Linguistic and content validation of a German-language PRO-CTCAE-based patient-reported outcomes instrument to evaluate the late effect symptom experience after allogeneic hematopoietic stem cell transplantation.
Kirsch M, Mitchell SA, Dobbels F, Stussi G, Basch E, Halter JP, De Geest S
Eur J Oncol Nurs 2015 Feb;19(1):66-74. Epub 2014 Sep 1 doi: 10.1016/j.ejon.2014.07.007. PMID: 25190633

Therapy

Daratumumab and antineoplastic therapy versus antineoplastic therapy only for adults with newly diagnosed multiple myeloma ineligible for transplant.
Langer P, John L, Monsef I, Scheid C, Piechotta V, Skoetz N
Cochrane Database Syst Rev 2024 May 2;5(5):CD013595. doi: 10.1002/14651858.CD013595.pub2. PMID: 38695605Free PMC Article
Pooled Safety Analysis of Single-Agent Lurbinectedin in Patients With Advanced Solid Tumours.
Leary A, Oaknin A, Trigo JM, Moreno V, Delord JP, Boni V, Braña I, Fernández C, Kahatt C, Nieto A, Cullell-Young M, Zeaiter A, Subbiah V
Eur J Cancer 2023 Oct;192:113259. Epub 2023 Jul 28 doi: 10.1016/j.ejca.2023.113259. PMID: 37634282
Patient-reported outcomes in CD30-directed CAR-T cells against relapsed/refractory CD30+ lymphomas.
Tschernia NP, Heiling H, Deal AM, Cheng C, Babinec C, Gonzalez M, Morrison JK, Dittus C, Dotti G, Beaven AW, Serody JS, Wood WA, Savoldo B, Grover NS
J Immunother Cancer 2023 Aug;11(8) doi: 10.1136/jitc-2023-006959. PMID: 37527906Free PMC Article
Hematologic abnormalities in Aicardi Goutières Syndrome.
Adang LA, Gavazzi F, D'Aiello R, Isaacs D, Bronner N, Arici ZS, Flores Z, Jan A, Scher C, Sherbini O, Behrens EM, Goldbach-Mansky R, Olson TS, Lambert MP, Sullivan KE, Teachey DT, Witmer C, Vanderver A, Shults J
Mol Genet Metab 2022 Aug;136(4):324-329. Epub 2022 Jun 16 doi: 10.1016/j.ymgme.2022.06.003. PMID: 35786528Free PMC Article
Bendamustine is safe and effective for lymphodepletion before tisagenlecleucel in patients with refractory or relapsed large B-cell lymphomas.
Ghilardi G, Chong EA, Svoboda J, Wohlfarth P, Nasta SD, Williamson S, Landsburg JD, Gerson JN, Barta SK, Pajarillo R, Myers J, Chen AI, Schachter L, Yelton R, Ballard HJ, Hodges Dwinal A, Gier S, Victoriano D, Weber E, Napier E, Garfall A, Porter DL, Jäger U, Maziarz RT, Ruella M, Schuster SJ
Ann Oncol 2022 Sep;33(9):916-928. Epub 2022 Jun 9 doi: 10.1016/j.annonc.2022.05.521. PMID: 35690221Free PMC Article

Prognosis

Fix low dose venetoclax-azacitidine treatment of unfit acute myeloid leukemia patients.
Miklos E, Oliver TP, Adam K, Eva K, Balazs K, Eszter K, Anett P, Viktoria GK, Jozsef H, Peter R
Eur J Haematol 2024 Aug;113(2):183-189. Epub 2024 Apr 21 doi: 10.1111/ejh.14213. PMID: 38644361
Applying the EHA/EBMT grading for ICAHT after CAR-T: comparative incidence and association with infections and mortality.
Rejeski K, Wang Y, Hansen DK, Iacoboni G, Bachy E, Bansal R, Penack O, Müller F, Bethge W, Munoz J, Mohty R, Bücklein VL, Barba P, Locke FL, Lin Y, Jain MD, Subklewe M
Blood Adv 2024 Apr 23;8(8):1857-1868. doi: 10.1182/bloodadvances.2023011767. PMID: 38181508Free PMC Article
Acute and chronic kidney injury during therapy for pediatric acute leukemia: A report from the Leukemia Electronic Abstraction of Records Network (LEARN).
Hsiao W, Li Y, Getz K, Cao L, Krause E, Ramos M, Lee J, Gramatges MM, Rabin KR, Scheurer ME, Aplenc R, Denburg M, Miller TP
Pediatr Blood Cancer 2023 Dec;70(12):e30696. Epub 2023 Sep 30 doi: 10.1002/pbc.30696. PMID: 37776085Free PMC Article
The Incidence of Ototoxicity in Patients Using Iron Chelators.
Derin S, Azık FM, Topal Y, Topal H, Karakuş V, Çetinkaya PU, Şahan M, Azık TE, Kocabaş CN
J Int Adv Otol 2017 Apr;13(1):136-139. Epub 2016 Nov 23 doi: 10.5152/iao.2016.1852. PMID: 27879229
Allergic reactions associated with pegaspargase in adults.
Chang A, Kim M, Seyer M, Patel S
Leuk Lymphoma 2016 Jul;57(7):1665-8. Epub 2016 Mar 14 doi: 10.3109/10428194.2015.1105369. PMID: 26461960

Clinical prediction guides

Applying the EHA/EBMT grading for ICAHT after CAR-T: comparative incidence and association with infections and mortality.
Rejeski K, Wang Y, Hansen DK, Iacoboni G, Bachy E, Bansal R, Penack O, Müller F, Bethge W, Munoz J, Mohty R, Bücklein VL, Barba P, Locke FL, Lin Y, Jain MD, Subklewe M
Blood Adv 2024 Apr 23;8(8):1857-1868. doi: 10.1182/bloodadvances.2023011767. PMID: 38181508Free PMC Article
Phase I non-randomized clinical trial of allogeneic natural killer cells infusion in acute myeloid leukemia patients.
Ahmadvand M, Barough MS, Barkhordar M, Faridfar A, Ghaderi A, Jalaeikhoo H, Rajaienejad M, Majidzadeh K, Ghavamzadeh A, Sarrami-Forooshani R
BMC Cancer 2023 Nov 10;23(1):1090. doi: 10.1186/s12885-023-11610-x. PMID: 37950209Free PMC Article
Patient-reported outcomes in CD30-directed CAR-T cells against relapsed/refractory CD30+ lymphomas.
Tschernia NP, Heiling H, Deal AM, Cheng C, Babinec C, Gonzalez M, Morrison JK, Dittus C, Dotti G, Beaven AW, Serody JS, Wood WA, Savoldo B, Grover NS
J Immunother Cancer 2023 Aug;11(8) doi: 10.1136/jitc-2023-006959. PMID: 37527906Free PMC Article
Bendamustine is safe and effective for lymphodepletion before tisagenlecleucel in patients with refractory or relapsed large B-cell lymphomas.
Ghilardi G, Chong EA, Svoboda J, Wohlfarth P, Nasta SD, Williamson S, Landsburg JD, Gerson JN, Barta SK, Pajarillo R, Myers J, Chen AI, Schachter L, Yelton R, Ballard HJ, Hodges Dwinal A, Gier S, Victoriano D, Weber E, Napier E, Garfall A, Porter DL, Jäger U, Maziarz RT, Ruella M, Schuster SJ
Ann Oncol 2022 Sep;33(9):916-928. Epub 2022 Jun 9 doi: 10.1016/j.annonc.2022.05.521. PMID: 35690221Free PMC Article
Treatment of a first patient with FLASH-radiotherapy.
Bourhis J, Sozzi WJ, Jorge PG, Gaide O, Bailat C, Duclos F, Patin D, Ozsahin M, Bochud F, Germond JF, Moeckli R, Vozenin MC
Radiother Oncol 2019 Oct;139:18-22. Epub 2019 Jul 11 doi: 10.1016/j.radonc.2019.06.019. PMID: 31303340

Recent systematic reviews

Daratumumab and antineoplastic therapy versus antineoplastic therapy only for adults with newly diagnosed multiple myeloma ineligible for transplant.
Langer P, John L, Monsef I, Scheid C, Piechotta V, Skoetz N
Cochrane Database Syst Rev 2024 May 2;5(5):CD013595. doi: 10.1002/14651858.CD013595.pub2. PMID: 38695605Free PMC Article
Upfront autologous hematopoietic stem cell transplantation consolidation for patients with aggressive B-cell lymphomas in first remission in the rituximab era: A systematic review and meta-analysis.
Epperla N, Hamadani M, Reljic T, Kharfan-Dabaja MA, Savani BN, Kumar A
Cancer 2019 Dec 15;125(24):4417-4425. Epub 2019 Aug 23 doi: 10.1002/cncr.32464. PMID: 31441943
Comparison of a restrictive versus liberal red cell transfusion policy for patients with myelodysplasia, aplastic anaemia, and other congenital bone marrow failure disorders.
Gu Y, Estcourt LJ, Doree C, Hopewell S, Vyas P
Cochrane Database Syst Rev 2015 Oct 5;2015(10):CD011577. doi: 10.1002/14651858.CD011577.pub2. PMID: 26436602Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...