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Benign Lung PEComa

MedGen UID:
1642990
Concept ID:
C4684822
Neoplastic Process

Definition

A benign lung tumor that arises from perivascular epithelioid cells (PECs). [from NCI]

Recent clinical studies

Etiology

Amante MF
World J Gastroenterol 2024 May 14;30(18):2374-2378. doi: 10.3748/wjg.v30.i18.2374. PMID: 38764772Free PMC Article
Travis WD, Brambilla E, Nicholson AG, Yatabe Y, Austin JHM, Beasley MB, Chirieac LR, Dacic S, Duhig E, Flieder DB, Geisinger K, Hirsch FR, Ishikawa Y, Kerr KM, Noguchi M, Pelosi G, Powell CA, Tsao MS, Wistuba I; WHO Panel
J Thorac Oncol 2015 Sep;10(9):1243-1260. doi: 10.1097/JTO.0000000000000630. PMID: 26291008
Martignoni G, Pea M, Zampini C, Brunelli M, Segala D, Zamboni G, Bonetti F
Semin Diagn Pathol 2015 Mar;32(2):140-59. Epub 2015 Feb 24 doi: 10.1053/j.semdp.2015.02.006. PMID: 25804448
Trotman-Dickenson B
Eur J Radiol 2014 Jan;83(1):39-46. Epub 2013 Dec 4 doi: 10.1016/j.ejrad.2013.11.027. PMID: 24342705
Folpe AL, Mentzel T, Lehr HA, Fisher C, Balzer BL, Weiss SW
Am J Surg Pathol 2005 Dec;29(12):1558-75. doi: 10.1097/01.pas.0000173232.22117.37. PMID: 16327428

Diagnosis

Travis WD, Brambilla E, Nicholson AG, Yatabe Y, Austin JHM, Beasley MB, Chirieac LR, Dacic S, Duhig E, Flieder DB, Geisinger K, Hirsch FR, Ishikawa Y, Kerr KM, Noguchi M, Pelosi G, Powell CA, Tsao MS, Wistuba I; WHO Panel
J Thorac Oncol 2015 Sep;10(9):1243-1260. doi: 10.1097/JTO.0000000000000630. PMID: 26291008
Trotman-Dickenson B
Eur J Radiol 2014 Jan;83(1):39-46. Epub 2013 Dec 4 doi: 10.1016/j.ejrad.2013.11.027. PMID: 24342705
Candaș F, Berber U, Yildizhan A, Yiyit N, Görür R, Ișitmangil T
Ann Thorac Surg 2013 Apr;95(4):1431-2. doi: 10.1016/j.athoracsur.2012.07.066. PMID: 23522204
Johnson SR
Eur Respir J 2006 May;27(5):1056-65. doi: 10.1183/09031936.06.00113303. PMID: 16707400
Pitts S, Oberstein EM, Glassberg MK
Clin Chest Med 2004 Jun;25(2):343-60. doi: 10.1016/j.ccm.2004.01.014. PMID: 15099894

Therapy

Cai Y, Guo H, Wang W, Li H, Sun H, Shi B, Zhang Y
Orphanet J Rare Dis 2018 Mar 27;13(1):43. doi: 10.1186/s13023-018-0781-y. PMID: 29587809Free PMC Article
Taveira-DaSilva AM, Alford CE, Levens ED, Kotz HL, Moss J
Obstet Gynecol 2012 Feb;119(2 Pt 2):438-442. doi: 10.1097/AOG.0b013e318240090e. PMID: 22270431Free PMC Article
Edelweiss M, Gupta N, Resetkova E
Ann Diagn Pathol 2007 Dec;11(6):421-6. Epub 2007 Oct 29 doi: 10.1016/j.anndiagpath.2006.12.015. PMID: 18022127

Prognosis

Amante MF
World J Gastroenterol 2024 May 14;30(18):2374-2378. doi: 10.3748/wjg.v30.i18.2374. PMID: 38764772Free PMC Article
Glasgow CG, El-Chemaly S, Moss J
Eur Respir Rev 2012 Sep 1;21(125):196-206. doi: 10.1183/09059180.00009311. PMID: 22941884Free PMC Article
Varma S, Gupta S, Talwar J, Forte F, Dhar M
J Nephrol 2011 Jan-Feb;24(1):18-22. doi: 10.5301/jn.2010.5451. PMID: 20349413
Walsh SN, Sangüeza OP
Semin Diagn Pathol 2009 Aug;26(3):123-30. doi: 10.1053/j.semdp.2009.09.002. PMID: 20043511
Folpe AL, Mentzel T, Lehr HA, Fisher C, Balzer BL, Weiss SW
Am J Surg Pathol 2005 Dec;29(12):1558-75. doi: 10.1097/01.pas.0000173232.22117.37. PMID: 16327428

Clinical prediction guides

Amante MF
World J Gastroenterol 2024 May 14;30(18):2374-2378. doi: 10.3748/wjg.v30.i18.2374. PMID: 38764772Free PMC Article
Varma S, Gupta S, Talwar J, Forte F, Dhar M
J Nephrol 2011 Jan-Feb;24(1):18-22. doi: 10.5301/jn.2010.5451. PMID: 20349413
Folpe AL, Mentzel T, Lehr HA, Fisher C, Balzer BL, Weiss SW
Am J Surg Pathol 2005 Dec;29(12):1558-75. doi: 10.1097/01.pas.0000173232.22117.37. PMID: 16327428
Pitts S, Oberstein EM, Glassberg MK
Clin Chest Med 2004 Jun;25(2):343-60. doi: 10.1016/j.ccm.2004.01.014. PMID: 15099894
Muir TE, Leslie KO, Popper H, Kitaichi M, Gagné E, Emelin JK, Vinters HV, Colby TV
Am J Surg Pathol 1998 Apr;22(4):465-72. doi: 10.1097/00000478-199804000-00012. PMID: 9537475

Recent systematic reviews

Ntanasis-Stathopoulos I, Kyriazoglou A, Tsilimigras DI, Tzanninis IG, Liontos M, Dimopoulos MA, Gavriatopoulou M
J BUON 2021 Jan-Feb;26(1):17-32. PMID: 33721428

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