U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Coma Greater than 24 Hours

MedGen UID:
1646242
•Concept ID:
C4683647
•
Finding

Definition

An indication that coma has lasted more than 24 hours. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVComa Greater than 24 Hours

Professional guidelines

PubMed

Continuous Versus Bolus Infusion of Hypertonic Saline in the Treatment of Symptomatic Hyponatremia Caused by SIAD.
Garrahy A, Dineen R, Hannon AM, Cuesta M, Tormey W, Sherlock M, Thompson CJ
J Clin Endocrinol Metab 2019 Sep 1;104(9):3595-3602. doi: 10.1210/jc.2019-00044. PMID: 30882872
Delineation of Criteria for Admission to Step Down in the Mild Traumatic Brain Injury Patient.
Bardes JM, Turner J, Bonasso P, Hobbs G, Wilson A
Am Surg 2016 Jan;82(1):36-40. PMID: 26802855Free PMC Article
Clinical policy: neuroimaging and decisionmaking in adult mild traumatic brain injury in the acute setting.
Jagoda AS, Bazarian JJ, Bruns JJ Jr, Cantrill SV, Gean AD, Howard PK, Ghajar J, Riggio S, Wright DW, Wears RL, Bakshy A, Burgess P, Wald MM, Whitson RR; American College of Emergency Physicians; Centers for Disease Control and Prevention
Ann Emerg Med 2008 Dec;52(6):714-48. doi: 10.1016/j.annemergmed.2008.08.021. PMID: 19027497

Recent clinical studies

Etiology

Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest.
Kjaergaard J, Møller JE, Schmidt H, Grand J, Mølstrøm S, Borregaard B, Venø S, Sarkisian L, Mamaev D, Jensen LO, Nyholm B, Høfsten DE, Josiassen J, Thomsen JH, Thune JJ, Obling LER, Lindholm MG, Frydland M, Meyer MAS, Winther-Jensen M, Beske RP, Frikke-Schmidt R, Wiberg S, Boesgaard S, Madsen SA, Jørgensen VL, Hassager C
N Engl J Med 2022 Oct 20;387(16):1456-1466. Epub 2022 Aug 27 doi: 10.1056/NEJMoa2208687. PMID: 36027564
Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest: The CAPITAL CHILL Randomized Clinical Trial.
Le May M, Osborne C, Russo J, So D, Chong AY, Dick A, Froeschl M, Glover C, Hibbert B, Marquis JF, De Roock S, Labinaz M, Bernick J, Marshall S, Maze R, Wells G
JAMA 2021 Oct 19;326(15):1494-1503. doi: 10.1001/jama.2021.15703. PMID: 34665203Free PMC Article
Life-Threatening Bleeding in Children: A Prospective Observational Study.
Leonard JC, Josephson CD, Luther JF, Wisniewski SR, Allen C, Chiusolo F, Davis AL, Finkelstein RA, Fitzgerald JC, Gaines BA, Goobie SM, Hanson SJ, Hewes HA, Johnson LH, McCollum MO, Muszynski JA, Nair AB, Rosenberg RB, Rouse TM, Sikavitsas A, Singleton MN, Steiner ME, Upperman JS, Vogel AM, Wills H, Winkler MK, Spinella PC
Crit Care Med 2021 Nov 1;49(11):1943-1954. doi: 10.1097/CCM.0000000000005075. PMID: 33990098Free PMC Article
Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm.
Lascarrou JB, Merdji H, Le Gouge A, Colin G, Grillet G, Girardie P, Coupez E, Dequin PF, Cariou A, Boulain T, Brule N, Frat JP, Asfar P, Pichon N, Landais M, Plantefeve G, Quenot JP, Chakarian JC, Sirodot M, Legriel S, Letheulle J, Thevenin D, Desachy A, Delahaye A, Botoc V, Vimeux S, Martino F, Giraudeau B, Reignier J; CRICS-TRIGGERSEP Group
N Engl J Med 2019 Dec 12;381(24):2327-2337. Epub 2019 Oct 2 doi: 10.1056/NEJMoa1906661. PMID: 31577396
Anticoagulant rodenticides.
Watt BE, Proudfoot AT, Bradberry SM, Vale JA
Toxicol Rev 2005;24(4):259-69. doi: 10.2165/00139709-200524040-00005. PMID: 16499407

Diagnosis

Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest.
Kjaergaard J, Møller JE, Schmidt H, Grand J, Mølstrøm S, Borregaard B, Venø S, Sarkisian L, Mamaev D, Jensen LO, Nyholm B, Høfsten DE, Josiassen J, Thomsen JH, Thune JJ, Obling LER, Lindholm MG, Frydland M, Meyer MAS, Winther-Jensen M, Beske RP, Frikke-Schmidt R, Wiberg S, Boesgaard S, Madsen SA, Jørgensen VL, Hassager C
N Engl J Med 2022 Oct 20;387(16):1456-1466. Epub 2022 Aug 27 doi: 10.1056/NEJMoa2208687. PMID: 36027564
Clinical Deterioration and Neurocritical Care Utilization in Pediatric Patients With Glasgow Coma Scale Score of 9-13 After Traumatic Brain Injury: Associations With Patient and Injury Characteristics.
Soysal E, Horvat CM, Simon DW, Wolf MS, Tyler-Kabara E, Gaines BA, Clark RSB, Kochanek PM, Bayir H
Pediatr Crit Care Med 2021 Nov 1;22(11):960-968. doi: 10.1097/PCC.0000000000002767. PMID: 34038066Free PMC Article
Prospective Study of Surgery for Traumatic Brain Injury in Addis Ababa, Ethiopia: Surgical Procedures, Complications, and Postoperative Outcomes.
Laeke T, Tirsit A, Kassahun A, Sahlu A, Yesehak B, Getahun S, Zenebe E, Deyassa N, Moen BE, Lund-Johansen M, Sundstrøm T
World Neurosurg 2021 Jun;150:e316-e323. Epub 2021 Mar 8 doi: 10.1016/j.wneu.2021.03.004. PMID: 33706016
Time course of plasma leptin concentrations after acute spontaneous basal ganglia hemorrhage.
Dong XQ, Huang M, Hu YY, Yu WH, Zhang ZY
World Neurosurg 2010 Aug-Sep;74(2-3):286-93. doi: 10.1016/j.wneu.2010.02.019. PMID: 21492562
Clinical policy: neuroimaging and decisionmaking in adult mild traumatic brain injury in the acute setting.
Jagoda AS, Bazarian JJ, Bruns JJ Jr, Cantrill SV, Gean AD, Howard PK, Ghajar J, Riggio S, Wright DW, Wears RL, Bakshy A, Burgess P, Wald MM, Whitson RR
J Emerg Nurs 2009 Apr;35(2):e5-40. doi: 10.1016/j.jen.2008.12.010. PMID: 19285163

Therapy

Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest.
Kjaergaard J, Møller JE, Schmidt H, Grand J, Mølstrøm S, Borregaard B, Venø S, Sarkisian L, Mamaev D, Jensen LO, Nyholm B, Høfsten DE, Josiassen J, Thomsen JH, Thune JJ, Obling LER, Lindholm MG, Frydland M, Meyer MAS, Winther-Jensen M, Beske RP, Frikke-Schmidt R, Wiberg S, Boesgaard S, Madsen SA, Jørgensen VL, Hassager C
N Engl J Med 2022 Oct 20;387(16):1456-1466. Epub 2022 Aug 27 doi: 10.1056/NEJMoa2208687. PMID: 36027564
Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest: The CAPITAL CHILL Randomized Clinical Trial.
Le May M, Osborne C, Russo J, So D, Chong AY, Dick A, Froeschl M, Glover C, Hibbert B, Marquis JF, De Roock S, Labinaz M, Bernick J, Marshall S, Maze R, Wells G
JAMA 2021 Oct 19;326(15):1494-1503. doi: 10.1001/jama.2021.15703. PMID: 34665203Free PMC Article
Life-Threatening Bleeding in Children: A Prospective Observational Study.
Leonard JC, Josephson CD, Luther JF, Wisniewski SR, Allen C, Chiusolo F, Davis AL, Finkelstein RA, Fitzgerald JC, Gaines BA, Goobie SM, Hanson SJ, Hewes HA, Johnson LH, McCollum MO, Muszynski JA, Nair AB, Rosenberg RB, Rouse TM, Sikavitsas A, Singleton MN, Steiner ME, Upperman JS, Vogel AM, Wills H, Winkler MK, Spinella PC
Crit Care Med 2021 Nov 1;49(11):1943-1954. doi: 10.1097/CCM.0000000000005075. PMID: 33990098Free PMC Article
Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm.
Lascarrou JB, Merdji H, Le Gouge A, Colin G, Grillet G, Girardie P, Coupez E, Dequin PF, Cariou A, Boulain T, Brule N, Frat JP, Asfar P, Pichon N, Landais M, Plantefeve G, Quenot JP, Chakarian JC, Sirodot M, Legriel S, Letheulle J, Thevenin D, Desachy A, Delahaye A, Botoc V, Vimeux S, Martino F, Giraudeau B, Reignier J; CRICS-TRIGGERSEP Group
N Engl J Med 2019 Dec 12;381(24):2327-2337. Epub 2019 Oct 2 doi: 10.1056/NEJMoa1906661. PMID: 31577396
Anticoagulant rodenticides.
Watt BE, Proudfoot AT, Bradberry SM, Vale JA
Toxicol Rev 2005;24(4):259-69. doi: 10.2165/00139709-200524040-00005. PMID: 16499407

Prognosis

Swallowing Dysfunction after Acute Stroke: The Incidence, Predictors and Outcome.
Londhe C, Agrawal A, Pednekar S, Pandey D, Khan MF
J Assoc Physicians India 2023 Aug;71(8):11-12. doi: 10.59556/japi.71.0301. PMID: 37651239
Comparison of qSOFA Score, SIRS Criteria, and SOFA Score as predictors of mortality in patients with sepsis.
Khan AM, Aslam SM
Ghana Med J 2022 Sep;56(3):191-197. doi: 10.4314/gmj.v56i3.9. PMID: 37448998Free PMC Article
Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest: The CAPITAL CHILL Randomized Clinical Trial.
Le May M, Osborne C, Russo J, So D, Chong AY, Dick A, Froeschl M, Glover C, Hibbert B, Marquis JF, De Roock S, Labinaz M, Bernick J, Marshall S, Maze R, Wells G
JAMA 2021 Oct 19;326(15):1494-1503. doi: 10.1001/jama.2021.15703. PMID: 34665203Free PMC Article
Trauma Quality Indicators' usage limitations in severe trauma patients.
Antunes PSL, LibÓrio PR, Shimoda GM, Pivetta LGA, Parreira JG, Assef JC
Rev Col Bras Cir 2021;48:e20202769. Epub 2021 Feb 24 doi: 10.1590/0100-6991e-20202769. PMID: 33656134Free PMC Article
Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm.
Lascarrou JB, Merdji H, Le Gouge A, Colin G, Grillet G, Girardie P, Coupez E, Dequin PF, Cariou A, Boulain T, Brule N, Frat JP, Asfar P, Pichon N, Landais M, Plantefeve G, Quenot JP, Chakarian JC, Sirodot M, Legriel S, Letheulle J, Thevenin D, Desachy A, Delahaye A, Botoc V, Vimeux S, Martino F, Giraudeau B, Reignier J; CRICS-TRIGGERSEP Group
N Engl J Med 2019 Dec 12;381(24):2327-2337. Epub 2019 Oct 2 doi: 10.1056/NEJMoa1906661. PMID: 31577396

Clinical prediction guides

Swallowing Dysfunction after Acute Stroke: The Incidence, Predictors and Outcome.
Londhe C, Agrawal A, Pednekar S, Pandey D, Khan MF
J Assoc Physicians India 2023 Aug;71(8):11-12. doi: 10.59556/japi.71.0301. PMID: 37651239
Long-term Multidomain Patterns of Change After Traumatic Brain Injury: A TRACK-TBI LONG Study.
Brett BL, Temkin N, Barber JK, Okonkwo DO, Stein M, Bodien YG, Corrigan J, Diaz-Arrastia R, Giacino JT, McCrea MA, Manley GT, Nelson LD; for TRACK-TBI Investigators
Neurology 2023 Aug 15;101(7):e740-e753. Epub 2023 Jun 21 doi: 10.1212/WNL.0000000000207501. PMID: 37344231Free PMC Article
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest.
Kjaergaard J, Møller JE, Schmidt H, Grand J, Mølstrøm S, Borregaard B, Venø S, Sarkisian L, Mamaev D, Jensen LO, Nyholm B, Høfsten DE, Josiassen J, Thomsen JH, Thune JJ, Obling LER, Lindholm MG, Frydland M, Meyer MAS, Winther-Jensen M, Beske RP, Frikke-Schmidt R, Wiberg S, Boesgaard S, Madsen SA, Jørgensen VL, Hassager C
N Engl J Med 2022 Oct 20;387(16):1456-1466. Epub 2022 Aug 27 doi: 10.1056/NEJMoa2208687. PMID: 36027564
Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest: The CAPITAL CHILL Randomized Clinical Trial.
Le May M, Osborne C, Russo J, So D, Chong AY, Dick A, Froeschl M, Glover C, Hibbert B, Marquis JF, De Roock S, Labinaz M, Bernick J, Marshall S, Maze R, Wells G
JAMA 2021 Oct 19;326(15):1494-1503. doi: 10.1001/jama.2021.15703. PMID: 34665203Free PMC Article
Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm.
Lascarrou JB, Merdji H, Le Gouge A, Colin G, Grillet G, Girardie P, Coupez E, Dequin PF, Cariou A, Boulain T, Brule N, Frat JP, Asfar P, Pichon N, Landais M, Plantefeve G, Quenot JP, Chakarian JC, Sirodot M, Legriel S, Letheulle J, Thevenin D, Desachy A, Delahaye A, Botoc V, Vimeux S, Martino F, Giraudeau B, Reignier J; CRICS-TRIGGERSEP Group
N Engl J Med 2019 Dec 12;381(24):2327-2337. Epub 2019 Oct 2 doi: 10.1056/NEJMoa1906661. PMID: 31577396

Recent systematic reviews

Clinical and cost-effectiveness of continuous subcutaneous insulin infusion for diabetes.
Colquitt JL, Green C, Sidhu MK, Hartwell D, Waugh N
Health Technol Assess 2004 Oct;8(43):iii, 1-171. doi: 10.3310/hta8430. PMID: 15488165

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...