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Grade 2 GGT Increased, CTCAE

MedGen UID:
1647149
•Concept ID:
C4685677
•
Finding

Definition

>2.5-5.0 x ULN if baseline was normal; >2.5-5.0 x baseline if baseline was abnormal [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 2 GGT Increased, CTCAE

Recent clinical studies

Etiology

Phase I study of metformin in combination with carboplatin/paclitaxel chemotherapy in patients with advanced epithelial ovarian cancer.
Broekman KE, Hof MAJ, Touw DJ, Gietema JA, Nijman HW, Lefrandt JD, Reyners AKL, Jalving M
Invest New Drugs 2020 Oct;38(5):1454-1462. Epub 2020 Mar 7 doi: 10.1007/s10637-020-00920-7. PMID: 32146550Free PMC Article

Therapy

Phase I study of metformin in combination with carboplatin/paclitaxel chemotherapy in patients with advanced epithelial ovarian cancer.
Broekman KE, Hof MAJ, Touw DJ, Gietema JA, Nijman HW, Lefrandt JD, Reyners AKL, Jalving M
Invest New Drugs 2020 Oct;38(5):1454-1462. Epub 2020 Mar 7 doi: 10.1007/s10637-020-00920-7. PMID: 32146550Free PMC Article

Clinical prediction guides

Phase I study of metformin in combination with carboplatin/paclitaxel chemotherapy in patients with advanced epithelial ovarian cancer.
Broekman KE, Hof MAJ, Touw DJ, Gietema JA, Nijman HW, Lefrandt JD, Reyners AKL, Jalving M
Invest New Drugs 2020 Oct;38(5):1454-1462. Epub 2020 Mar 7 doi: 10.1007/s10637-020-00920-7. PMID: 32146550Free PMC Article

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