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Unresectable Dedifferentiated Liposarcoma

MedGen UID:
1652941
Concept ID:
C4725862
Neoplastic Process

Definition

Dedifferentiated liposarcoma that is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Dedifferentiated Liposarcoma

Professional guidelines

PubMed

Qu G, Zhang C, Tian Z, Yao W
Curr Treat Options Oncol 2024 Oct;25(10):1289-1296. Epub 2024 Sep 20 doi: 10.1007/s11864-024-01262-9. PMID: 39302575
Dominguez DA, Sampath S, Agulnik M, Liang Y, Nguyen B, Trisal V, Melstrom LG, Lewis AG, Paz IB, Roberts RF, Tseng WW
Curr Oncol 2023 Apr 29;30(5):4618-4631. doi: 10.3390/curroncol30050349. PMID: 37232807Free PMC Article
Schöffski P
Oncol Res Treat 2022;45(9):525-543. Epub 2022 May 24 doi: 10.1159/000524939. PMID: 35609512

Recent clinical studies

Etiology

Qu G, Zhang C, Tian Z, Yao W
Curr Treat Options Oncol 2024 Oct;25(10):1289-1296. Epub 2024 Sep 20 doi: 10.1007/s11864-024-01262-9. PMID: 39302575
Dominguez DA, Sampath S, Agulnik M, Liang Y, Nguyen B, Trisal V, Melstrom LG, Lewis AG, Paz IB, Roberts RF, Tseng WW
Curr Oncol 2023 Apr 29;30(5):4618-4631. doi: 10.3390/curroncol30050349. PMID: 37232807Free PMC Article
Jagosky MH, Anderson CJ, Symanowski JT, Steuerwald NM, Farhangfar CJ, Baldrige EA, Benbow JH, Livingston MB, Patt JC, Ahrens WA, Kneisl JS, Kim ES
Cancer Med 2023 Mar;12(6):7029-7038. Epub 2022 Dec 4 doi: 10.1002/cam4.5502. PMID: 36464833Free PMC Article
Suarez-Kelly LP, Baldi GG, Gronchi A
Expert Opin Pharmacother 2019 Aug;20(12):1503-1515. Epub 2019 May 28 doi: 10.1080/14656566.2019.1618271. PMID: 31136210
Tawbi HA, Burgess M, Bolejack V, Van Tine BA, Schuetze SM, Hu J, D'Angelo S, Attia S, Riedel RF, Priebat DA, Movva S, Davis LE, Okuno SH, Reed DR, Crowley J, Butterfield LH, Salazar R, Rodriguez-Canales J, Lazar AJ, Wistuba II, Baker LH, Maki RG, Reinke D, Patel S
Lancet Oncol 2017 Nov;18(11):1493-1501. Epub 2017 Oct 4 doi: 10.1016/S1470-2045(17)30624-1. PMID: 28988646Free PMC Article

Diagnosis

Qu G, Zhang C, Tian Z, Yao W
Curr Treat Options Oncol 2024 Oct;25(10):1289-1296. Epub 2024 Sep 20 doi: 10.1007/s11864-024-01262-9. PMID: 39302575
Jagosky MH, Anderson CJ, Symanowski JT, Steuerwald NM, Farhangfar CJ, Baldrige EA, Benbow JH, Livingston MB, Patt JC, Ahrens WA, Kneisl JS, Kim ES
Cancer Med 2023 Mar;12(6):7029-7038. Epub 2022 Dec 4 doi: 10.1002/cam4.5502. PMID: 36464833Free PMC Article
Schöffski P
Oncol Res Treat 2022;45(9):525-543. Epub 2022 May 24 doi: 10.1159/000524939. PMID: 35609512
Gounder M, Abdul Razak AR, Gilligan AM, Leong H, Ma X, Somaiah N, Chawla SP, Martin-Broto J, Grignani G, Schuetze SM, Vincenzi B, Wagner AJ, Chmielowski B, Jones RL, Shah J, Shacham S, Kauffman M, Riedel RF, Attia S
Future Oncol 2021 Aug;17(22):2923-2939. Epub 2021 Apr 15 doi: 10.2217/fon-2021-0284. PMID: 33855868Free PMC Article
Abbas Manji G, Singer S, Koff A, Schwartz GK
Am Soc Clin Oncol Educ Book 2015:213-8. doi: 10.14694/EdBook_AM.2015.35.213. PMID: 25993159

Therapy

D'Angelo SP, Araujo DM, Abdul Razak AR, Agulnik M, Attia S, Blay JY, Carrasco Garcia I, Charlson JA, Choy E, Demetri GD, Druta M, Forcade E, Ganjoo KN, Glod J, Keedy VL, Le Cesne A, Liebner DA, Moreno V, Pollack SM, Schuetze SM, Schwartz GK, Strauss SJ, Tap WD, Thistlethwaite F, Valverde Morales CM, Wagner MJ, Wilky BA, McAlpine C, Hudson L, Navenot JM, Wang T, Bai J, Rafail S, Wang R, Sun A, Fernandes L, Van Winkle E, Elefant E, Lunt C, Norry E, Williams D, Biswas S, Van Tine BA
Lancet 2024 Apr 13;403(10435):1460-1471. Epub 2024 Mar 27 doi: 10.1016/S0140-6736(24)00319-2. PMID: 38554725Free PMC Article
Suarez-Kelly LP, Baldi GG, Gronchi A
Expert Opin Pharmacother 2019 Aug;20(12):1503-1515. Epub 2019 May 28 doi: 10.1080/14656566.2019.1618271. PMID: 31136210
Tawbi HA, Burgess M, Bolejack V, Van Tine BA, Schuetze SM, Hu J, D'Angelo S, Attia S, Riedel RF, Priebat DA, Movva S, Davis LE, Okuno SH, Reed DR, Crowley J, Butterfield LH, Salazar R, Rodriguez-Canales J, Lazar AJ, Wistuba II, Baker LH, Maki RG, Reinke D, Patel S
Lancet Oncol 2017 Nov;18(11):1493-1501. Epub 2017 Oct 4 doi: 10.1016/S1470-2045(17)30624-1. PMID: 28988646Free PMC Article
Zijoo R, von Mehren M
Expert Opin Pharmacother 2016 Oct;17(14):1953-62. Epub 2016 Sep 15 doi: 10.1080/14656566.2016.1229304. PMID: 27615729
Abbas Manji G, Singer S, Koff A, Schwartz GK
Am Soc Clin Oncol Educ Book 2015:213-8. doi: 10.14694/EdBook_AM.2015.35.213. PMID: 25993159

Prognosis

Qu G, Zhang C, Tian Z, Yao W
Curr Treat Options Oncol 2024 Oct;25(10):1289-1296. Epub 2024 Sep 20 doi: 10.1007/s11864-024-01262-9. PMID: 39302575
Jagosky MH, Anderson CJ, Symanowski JT, Steuerwald NM, Farhangfar CJ, Baldrige EA, Benbow JH, Livingston MB, Patt JC, Ahrens WA, Kneisl JS, Kim ES
Cancer Med 2023 Mar;12(6):7029-7038. Epub 2022 Dec 4 doi: 10.1002/cam4.5502. PMID: 36464833Free PMC Article
Kobayashi H, Iwata S, Wakamatsu T, Hayakawa K, Yonemoto T, Wasa J, Oka H, Ueda T, Tanaka S
Cancer 2020 Mar 15;126(6):1253-1263. Epub 2019 Dec 11 doi: 10.1002/cncr.32661. PMID: 31825533
Tawbi HA, Burgess M, Bolejack V, Van Tine BA, Schuetze SM, Hu J, D'Angelo S, Attia S, Riedel RF, Priebat DA, Movva S, Davis LE, Okuno SH, Reed DR, Crowley J, Butterfield LH, Salazar R, Rodriguez-Canales J, Lazar AJ, Wistuba II, Baker LH, Maki RG, Reinke D, Patel S
Lancet Oncol 2017 Nov;18(11):1493-1501. Epub 2017 Oct 4 doi: 10.1016/S1470-2045(17)30624-1. PMID: 28988646Free PMC Article
Hogg ME, Wayne JD
Surg Oncol Clin N Am 2012 Apr;21(2):333-40. Epub 2012 Jan 28 doi: 10.1016/j.soc.2011.12.007. PMID: 22365523

Clinical prediction guides

Nakayama S, Matsumura K, Fukuda A, Seno H
Clin J Gastroenterol 2023 Jun;16(3):361-365. Epub 2023 Feb 3 doi: 10.1007/s12328-023-01762-5. PMID: 36735203
Gounder M, Abdul Razak AR, Gilligan AM, Leong H, Ma X, Somaiah N, Chawla SP, Martin-Broto J, Grignani G, Schuetze SM, Vincenzi B, Wagner AJ, Chmielowski B, Jones RL, Shah J, Shacham S, Kauffman M, Riedel RF, Attia S
Future Oncol 2021 Aug;17(22):2923-2939. Epub 2021 Apr 15 doi: 10.2217/fon-2021-0284. PMID: 33855868Free PMC Article
Li ZK, Liu J, Deng YT, Jiang Y
Anticancer Drugs 2021 Feb 1;32(2):210-214. doi: 10.1097/CAD.0000000000001023. PMID: 33290314
Ghadimi MP, Liu P, Peng T, Bolshakov S, Young ED, Torres KE, Colombo C, Hoffman A, Broccoli D, Hornick JL, Lazar AJ, Pisters P, Pollock RE, Lev D
Cancer 2011 Dec 1;117(23):5359-69. Epub 2011 May 19 doi: 10.1002/cncr.26195. PMID: 21598240Free PMC Article
Vander Salm TJ
Semin Thorac Cardiovasc Surg 2000 Apr;12(2):89-100. doi: 10.1053/ct.2000.5080. PMID: 10807431

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