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Recurrent Endometrial Clear Cell Adenocarcinoma

MedGen UID:
1653973
•Concept ID:
C4744398
•
Neoplastic Process

Definition

The reemergence of endometrial clear cell adenocarcinoma after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Endometrial Clear Cell Adenocarcinoma

Professional guidelines

PubMed

The role of adjuvant treatment for early-stage uterine clear cell carcinomas.
Orellana TJ, Garrett AA, Soong TR, Rives T, Courtney-Brooks M, Taylor SE, Lesnock J, Berger J, Boisen M, Coffman L, Buckanovich R, Mahdi H, Comerci JC, Beriwal S, Sukumvanich P, Edwards RP, Bhargava R, Olawaiye AB
Gynecol Oncol 2023 Mar;170:77-83. Epub 2023 Jan 13 doi: 10.1016/j.ygyno.2022.12.024. PMID: 36641903Free PMC Article
Advances in the management of endometrial adenocarcinoma. A review.
Irvin WP, Rice LW, Berkowitz RS
J Reprod Med 2002 Mar;47(3):173-89; discussion 189-90. PMID: 11933681
Clear-cell and papillary serous cancer: treatment options.
Tropé C, Kristensen GB, Abeler VM
Best Pract Res Clin Obstet Gynaecol 2001 Jun;15(3):433-46. doi: 10.1053/beog.2000.0187. PMID: 11476564

Recent clinical studies

Etiology

Correlation of clinicopathological and prognostic characteristics between endometriosis-associated and primary ovarian cancer.
Wang H, Chen C, Wang D, Zhu Y, Chen P
BMC Cancer 2023 Dec 8;23(1):1210. doi: 10.1186/s12885-023-11641-4. PMID: 38066448Free PMC Article
A phase 2 study of dasatinib in recurrent clear cell carcinoma of the ovary, fallopian tube, peritoneum or endometrium: NRG oncology/gynecologic oncology group study 0283.
O'Cearbhaill RE, Miller A, Soslow RA, Lankes HA, DeLair D, Segura S, Chavan S, Zamarin D, DeBernardo R, Moore K, Moroney J, Shahin M, Thaker PH, Wahner-Hendrickson AE, Aghajanian C
Gynecol Oncol 2023 Sep;176:16-24. Epub 2023 Jul 5 doi: 10.1016/j.ygyno.2023.06.021. PMID: 37418832Free PMC Article
Clear cell carcinoma of the endometrium.
Bogani G, Ray-Coquard I, Concin N, Ngoi NYL, Morice P, Enomoto T, Takehara K, Denys H, Lorusso D, Coleman R, Vaughan MM, Takano M, Provencher D, Sagae S, Wimberger P, Póka R, Segev Y, Kim SI, Kim JW, Candido Dos Reis FJ, Mariani A, Leitao MM Jr, Makker V, Rustum NA, Vergote I, Zannoni GF, Tan DSP, McCormack M, Bini M, Lopez S, Raspagliesi F, Panici PB, di Donato V, Muzii L, Colombo N, Scambia G, Pignata S, Monk BJ
Gynecol Oncol 2022 Mar;164(3):658-666. Epub 2022 Jan 19 doi: 10.1016/j.ygyno.2022.01.012. PMID: 35063279
Clear cell carcinoma of ovary and uterus.
Glasspool RM, McNeish IA
Curr Oncol Rep 2013 Dec;15(6):566-72. doi: 10.1007/s11912-013-0346-0. PMID: 24114188
Endometrial cancer.
Greven KM, Corn BW
Curr Probl Cancer 1997 Mar-Apr;21(2):65-127. doi: 10.1016/s0147-0272(97)80002-5. PMID: 9128804

Diagnosis

Correlation of clinicopathological and prognostic characteristics between endometriosis-associated and primary ovarian cancer.
Wang H, Chen C, Wang D, Zhu Y, Chen P
BMC Cancer 2023 Dec 8;23(1):1210. doi: 10.1186/s12885-023-11641-4. PMID: 38066448Free PMC Article
Extrauterine Mesonephric-like Carcinoma: A Comprehensive Single Institution Study of 33 Cases.
Euscher ED, Marques-Piubelli ML, Ramalingam P, Wistuba I, Lawson BC, Frumovitz M, Malpica A
Am J Surg Pathol 2023 Jun 1;47(6):635-648. Epub 2023 Apr 6 doi: 10.1097/PAS.0000000000002039. PMID: 37026792
Should endometrial clear cell carcinoma be classified as Type II endometrial carcinoma?
Bae HS, Kim H, Young Kwon S, Kim KR, Song JY, Kim I
Int J Gynecol Pathol 2015 Jan;34(1):74-84. doi: 10.1097/PGP.0000000000000111. PMID: 25473756
Clear-cell and papillary serous cancer: treatment options.
Tropé C, Kristensen GB, Abeler VM
Best Pract Res Clin Obstet Gynaecol 2001 Jun;15(3):433-46. doi: 10.1053/beog.2000.0187. PMID: 11476564
Endometrial cancer.
Greven KM, Corn BW
Curr Probl Cancer 1997 Mar-Apr;21(2):65-127. doi: 10.1016/s0147-0272(97)80002-5. PMID: 9128804

Therapy

A phase 2 study of dasatinib in recurrent clear cell carcinoma of the ovary, fallopian tube, peritoneum or endometrium: NRG oncology/gynecologic oncology group study 0283.
O'Cearbhaill RE, Miller A, Soslow RA, Lankes HA, DeLair D, Segura S, Chavan S, Zamarin D, DeBernardo R, Moore K, Moroney J, Shahin M, Thaker PH, Wahner-Hendrickson AE, Aghajanian C
Gynecol Oncol 2023 Sep;176:16-24. Epub 2023 Jul 5 doi: 10.1016/j.ygyno.2023.06.021. PMID: 37418832Free PMC Article
Adjuvant therapy of uterine clear cell carcinoma: a review.
Xu Y, Hanna RK, Elshaikh MA
Arch Gynecol Obstet 2016 Mar;293(3):485-92. Epub 2015 Dec 1 doi: 10.1007/s00404-015-3973-x. PMID: 26626183
Clear cell carcinoma of ovary and uterus.
Glasspool RM, McNeish IA
Curr Oncol Rep 2013 Dec;15(6):566-72. doi: 10.1007/s11912-013-0346-0. PMID: 24114188
Systemic therapy in metastatic or recurrent endometrial cancer.
Pectasides D, Pectasides E, Economopoulos T
Cancer Treat Rev 2007 Apr;33(2):177-90. Epub 2006 Dec 29 doi: 10.1016/j.ctrv.2006.10.007. PMID: 17196749
Endometrial cancer.
Greven KM, Corn BW
Curr Probl Cancer 1997 Mar-Apr;21(2):65-127. doi: 10.1016/s0147-0272(97)80002-5. PMID: 9128804

Prognosis

Correlation of clinicopathological and prognostic characteristics between endometriosis-associated and primary ovarian cancer.
Wang H, Chen C, Wang D, Zhu Y, Chen P
BMC Cancer 2023 Dec 8;23(1):1210. doi: 10.1186/s12885-023-11641-4. PMID: 38066448Free PMC Article
A phase 2 study of dasatinib in recurrent clear cell carcinoma of the ovary, fallopian tube, peritoneum or endometrium: NRG oncology/gynecologic oncology group study 0283.
O'Cearbhaill RE, Miller A, Soslow RA, Lankes HA, DeLair D, Segura S, Chavan S, Zamarin D, DeBernardo R, Moore K, Moroney J, Shahin M, Thaker PH, Wahner-Hendrickson AE, Aghajanian C
Gynecol Oncol 2023 Sep;176:16-24. Epub 2023 Jul 5 doi: 10.1016/j.ygyno.2023.06.021. PMID: 37418832Free PMC Article
Clear cell carcinoma of the endometrium.
Bogani G, Ray-Coquard I, Concin N, Ngoi NYL, Morice P, Enomoto T, Takehara K, Denys H, Lorusso D, Coleman R, Vaughan MM, Takano M, Provencher D, Sagae S, Wimberger P, Póka R, Segev Y, Kim SI, Kim JW, Candido Dos Reis FJ, Mariani A, Leitao MM Jr, Makker V, Rustum NA, Vergote I, Zannoni GF, Tan DSP, McCormack M, Bini M, Lopez S, Raspagliesi F, Panici PB, di Donato V, Muzii L, Colombo N, Scambia G, Pignata S, Monk BJ
Gynecol Oncol 2022 Mar;164(3):658-666. Epub 2022 Jan 19 doi: 10.1016/j.ygyno.2022.01.012. PMID: 35063279
Clear cell carcinoma of ovary and uterus.
Glasspool RM, McNeish IA
Curr Oncol Rep 2013 Dec;15(6):566-72. doi: 10.1007/s11912-013-0346-0. PMID: 24114188
Endometrial cancer.
Greven KM, Corn BW
Curr Probl Cancer 1997 Mar-Apr;21(2):65-127. doi: 10.1016/s0147-0272(97)80002-5. PMID: 9128804

Clinical prediction guides

Comprehensive Bioinformatic Investigation of TP53 Dysregulation in Diverse Cancer Landscapes.
Khan R, Pari B, Puszynski K
Genes (Basel) 2024 Apr 30;15(5) doi: 10.3390/genes15050577. PMID: 38790205Free PMC Article
A phase 2 study of dasatinib in recurrent clear cell carcinoma of the ovary, fallopian tube, peritoneum or endometrium: NRG oncology/gynecologic oncology group study 0283.
O'Cearbhaill RE, Miller A, Soslow RA, Lankes HA, DeLair D, Segura S, Chavan S, Zamarin D, DeBernardo R, Moore K, Moroney J, Shahin M, Thaker PH, Wahner-Hendrickson AE, Aghajanian C
Gynecol Oncol 2023 Sep;176:16-24. Epub 2023 Jul 5 doi: 10.1016/j.ygyno.2023.06.021. PMID: 37418832Free PMC Article
Extrauterine Mesonephric-like Carcinoma: A Comprehensive Single Institution Study of 33 Cases.
Euscher ED, Marques-Piubelli ML, Ramalingam P, Wistuba I, Lawson BC, Frumovitz M, Malpica A
Am J Surg Pathol 2023 Jun 1;47(6):635-648. Epub 2023 Apr 6 doi: 10.1097/PAS.0000000000002039. PMID: 37026792
The role of HER2 as a therapeutic biomarker in gynaecological malignancy: potential for use beyond uterine serous carcinoma.
Talia KL, Banet N, Buza N
Pathology 2023 Feb;55(1):8-18. Epub 2022 Nov 23 doi: 10.1016/j.pathol.2022.11.004. PMID: 36503635
Clear cell and papillary serous endometrial carcinomas: survival in a series of 128 cases.
Scarfone G, Secomandi R, Parazzini F, Viganò R, Mangili G, Frigerio L, Villa A, Tateo S, Ricci E, Bolis G
Arch Gynecol Obstet 2013 Feb;287(2):351-6. Epub 2012 Oct 26 doi: 10.1007/s00404-012-2586-x. PMID: 23100038

Recent systematic reviews

Minimally invasive surgery versus open surgery in high-risk histologic endometrial cancer patients: A meta-analysis.
Kim NR, Lee AJ, Yang EJ, So KA, Lee SJ, Kim TJ, Shim SH
Gynecol Oncol 2022 Aug;166(2):236-244. Epub 2022 Jun 17 doi: 10.1016/j.ygyno.2022.06.004. PMID: 35725657
Comparison of minimally invasive surgery with laparotomic approach in the treatment of high risk endometrial cancer: A systematic review.
Scaletta G, Dinoi G, Capozzi V, Cianci S, Pelligra S, Ergasti R, Fagotti A, Scambia G, Fanfani F
Eur J Surg Oncol 2020 May;46(5):782-788. Epub 2019 Dec 2 doi: 10.1016/j.ejso.2019.11.519. PMID: 31818527
Comparative safety and effectiveness of robot-assisted laparoscopic hysterectomy versus conventional laparoscopy and laparotomy for endometrial cancer: A systematic review and meta-analysis.
Park DA, Lee DH, Kim SW, Lee SH
Eur J Surg Oncol 2016 Sep;42(9):1303-14. Epub 2016 Jun 29 doi: 10.1016/j.ejso.2016.06.400. PMID: 27439723

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