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Grade 1 Neonatal Hypotension, AE

MedGen UID:
1656873
•Concept ID:
C4743842
•
Finding
Synonym: Grade 1 Neonatal Hypotension, Adverse Event

Definition

An adverse event in a newborn characterized by transient (less than 60 minutes), asymptomatic hypotension; not affecting perfusion; not requiring intervention. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 1 Neonatal Hypotension, AE

Professional guidelines

PubMed

Epidural versus non-epidural or no analgesia for pain management in labour.
Anim-Somuah M, Smyth RM, Cyna AM, Cuthbert A
Cochrane Database Syst Rev 2018 May 21;5(5):CD000331. doi: 10.1002/14651858.CD000331.pub4. PMID: 29781504Free PMC Article
Beta-blockers for prevention and treatment of retinopathy of prematurity in preterm infants.
Kaempfen S, Neumann RP, Jost K, Schulzke SM
Cochrane Database Syst Rev 2018 Mar 2;3(3):CD011893. doi: 10.1002/14651858.CD011893.pub2. PMID: 29499081Free PMC Article
Efficacy and Safety of 2% Topical Propranolol Cream for the Treatment of Proliferating Infantile Strawberry Hemangiomas.
Wang Y, Zhang X, Yang Y, Zhang J, Yang Y, Lu Y
Indian J Pediatr 2017 Jun;84(6):425-429. Epub 2017 Feb 14 doi: 10.1007/s12098-017-2303-7. PMID: 28194699

Recent clinical studies

Etiology

Opioids for procedural pain in neonates.
Kinoshita M, Olsson E, Borys F, Bruschettini M
Cochrane Database Syst Rev 2023 Jun 23;6(6):CD015056. doi: 10.1002/14651858.CD015056.pub3. PMID: 37350685Free PMC Article
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
Chooi C, Cox JJ, Lumb RS, Middleton P, Chemali M, Emmett RS, Simmons SW, Cyna AM
Cochrane Database Syst Rev 2020 Jul 1;7(7):CD002251. doi: 10.1002/14651858.CD002251.pub4. PMID: 32619039Free PMC Article
Antihypertensive drug therapy for mild to moderate hypertension during pregnancy.
Abalos E, Duley L, Steyn DW, Gialdini C
Cochrane Database Syst Rev 2018 Oct 1;10(10):CD002252. doi: 10.1002/14651858.CD002252.pub4. PMID: 30277556Free PMC Article
Epidural versus non-epidural or no analgesia for pain management in labour.
Anim-Somuah M, Smyth RM, Cyna AM, Cuthbert A
Cochrane Database Syst Rev 2018 May 21;5(5):CD000331. doi: 10.1002/14651858.CD000331.pub4. PMID: 29781504Free PMC Article
Beta-blockers for prevention and treatment of retinopathy of prematurity in preterm infants.
Kaempfen S, Neumann RP, Jost K, Schulzke SM
Cochrane Database Syst Rev 2018 Mar 2;3(3):CD011893. doi: 10.1002/14651858.CD011893.pub2. PMID: 29499081Free PMC Article

Diagnosis

Opioids for procedural pain in neonates.
Kinoshita M, Olsson E, Borys F, Bruschettini M
Cochrane Database Syst Rev 2023 Jun 23;6(6):CD015056. doi: 10.1002/14651858.CD015056.pub3. PMID: 37350685Free PMC Article
Early (< 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants.
Doyle LW, Cheong JL, Hay S, Manley BJ, Halliday HL
Cochrane Database Syst Rev 2021 Oct 21;10(10):CD001146. doi: 10.1002/14651858.CD001146.pub6. PMID: 34674229Free PMC Article
Comparing peri-operative complications of paediatric and adult anaesthesia: A retrospective cohort study of 81 267 cases.
Westerkamp AC, de Geus AF, Molenbuur B, Meyer P, Wietasch JKG, Struys MMRF, Hendriks HGD
Eur J Anaesthesiol 2018 Apr;35(4):280-288. doi: 10.1097/EJA.0000000000000769. PMID: 29334510
Arrhythmias in Children in Early Postoperative Period After Cardiac Surgery.
Sahu MK, Das A, Siddharth B, Talwar S, Singh SP, Abraham A, Choudhury A
World J Pediatr Congenit Heart Surg 2018 Jan;9(1):38-46. doi: 10.1177/2150135117737687. PMID: 29310559
Morphine, hypotension, and adverse outcomes among preterm neonates: who's to blame? Secondary results from the NEOPAIN trial.
Hall RW, Kronsberg SS, Barton BA, Kaiser JR, Anand KJ; NEOPAIN Trial Investigators Group
Pediatrics 2005 May;115(5):1351-9. doi: 10.1542/peds.2004-1398. PMID: 15867047

Therapy

Opioids for procedural pain in neonates.
Kinoshita M, Olsson E, Borys F, Bruschettini M
Cochrane Database Syst Rev 2023 Jun 23;6(6):CD015056. doi: 10.1002/14651858.CD015056.pub3. PMID: 37350685Free PMC Article
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
Chooi C, Cox JJ, Lumb RS, Middleton P, Chemali M, Emmett RS, Simmons SW, Cyna AM
Cochrane Database Syst Rev 2020 Jul 1;7(7):CD002251. doi: 10.1002/14651858.CD002251.pub4. PMID: 32619039Free PMC Article
Antihypertensive drug therapy for mild to moderate hypertension during pregnancy.
Abalos E, Duley L, Steyn DW, Gialdini C
Cochrane Database Syst Rev 2018 Oct 1;10(10):CD002252. doi: 10.1002/14651858.CD002252.pub4. PMID: 30277556Free PMC Article
Anaesthesia, surgery, and life-threatening allergic reactions: epidemiology and clinical features of perioperative anaphylaxis in the 6th National Audit Project (NAP6).
Harper NJN, Cook TM, Garcez T, Farmer L, Floss K, Marinho S, Torevell H, Warner A, Ferguson K, Hitchman J, Egner W, Kemp H, Thomas M, Lucas DN, Nasser S, Karanam S, Kong KL, Farooque S, Bellamy M, McGuire N
Br J Anaesth 2018 Jul;121(1):159-171. Epub 2018 May 21 doi: 10.1016/j.bja.2018.04.014. PMID: 29935567
Epidural versus non-epidural or no analgesia for pain management in labour.
Anim-Somuah M, Smyth RM, Cyna AM, Cuthbert A
Cochrane Database Syst Rev 2018 May 21;5(5):CD000331. doi: 10.1002/14651858.CD000331.pub4. PMID: 29781504Free PMC Article

Prognosis

Evaluating the Safety of Oral Propranolol Therapy in Patients With PHACE Syndrome.
Olsen GM, Hansen LM, Stefanko NS, Mathes E, Puttgen KB, Tollefson MM, Lauren C, Mancini AJ, McCuaig CC, Frieden IJ, Adams D, Baselga E, Chamlin S, Gupta D, Frommelt P, Garzon MC, Horii K, Klajn J, Maheshwari M, Newell B, Nguyen HL, Nopper A, Powell J, Siegel DH, Drolet BA
JAMA Dermatol 2020 Feb 1;156(2):186-190. doi: 10.1001/jamadermatol.2019.3839. PMID: 31825455Free PMC Article
Anaesthesia, surgery, and life-threatening allergic reactions: epidemiology and clinical features of perioperative anaphylaxis in the 6th National Audit Project (NAP6).
Harper NJN, Cook TM, Garcez T, Farmer L, Floss K, Marinho S, Torevell H, Warner A, Ferguson K, Hitchman J, Egner W, Kemp H, Thomas M, Lucas DN, Nasser S, Karanam S, Kong KL, Farooque S, Bellamy M, McGuire N
Br J Anaesth 2018 Jul;121(1):159-171. Epub 2018 May 21 doi: 10.1016/j.bja.2018.04.014. PMID: 29935567
Arrhythmias in Children in Early Postoperative Period After Cardiac Surgery.
Sahu MK, Das A, Siddharth B, Talwar S, Singh SP, Abraham A, Choudhury A
World J Pediatr Congenit Heart Surg 2018 Jan;9(1):38-46. doi: 10.1177/2150135117737687. PMID: 29310559
Arginine supplementation for prevention of necrotising enterocolitis in preterm infants.
Shah PS, Shah VS, Kelly LE
Cochrane Database Syst Rev 2017 Apr 11;4(4):CD004339. doi: 10.1002/14651858.CD004339.pub4. PMID: 28399330Free PMC Article
Efficacy and safety of umbilical cord milking at birth: a systematic review and meta-analysis.
Al-Wassia H, Shah PS
JAMA Pediatr 2015 Jan;169(1):18-25. doi: 10.1001/jamapediatrics.2014.1906. PMID: 25365246

Clinical prediction guides

Opioids for procedural pain in neonates.
Kinoshita M, Olsson E, Borys F, Bruschettini M
Cochrane Database Syst Rev 2023 Jun 23;6(6):CD015056. doi: 10.1002/14651858.CD015056.pub3. PMID: 37350685Free PMC Article
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
Chooi C, Cox JJ, Lumb RS, Middleton P, Chemali M, Emmett RS, Simmons SW, Cyna AM
Cochrane Database Syst Rev 2020 Jul 1;7(7):CD002251. doi: 10.1002/14651858.CD002251.pub4. PMID: 32619039Free PMC Article
Epidural versus non-epidural or no analgesia for pain management in labour.
Anim-Somuah M, Smyth RM, Cyna AM, Cuthbert A
Cochrane Database Syst Rev 2018 May 21;5(5):CD000331. doi: 10.1002/14651858.CD000331.pub4. PMID: 29781504Free PMC Article
Intravenous midazolam infusion for sedation of infants in the neonatal intensive care unit.
Ng E, Taddio A, Ohlsson A
Cochrane Database Syst Rev 2017 Jan 31;1(1):CD002052. doi: 10.1002/14651858.CD002052.pub3. PMID: 28141899Free PMC Article
Efficacy of propranolol for cutaneous hemangiomas in premature children.
Brazzelli V, Giorgini C, Barruscotti S, Codazzi CA, Mannarino S, Tzialla C, Stronati M, Marseglia GL, Borroni G
G Ital Dermatol Venereol 2016 Oct;151(5):485-91. Epub 2015 Feb 18 PMID: 25692776

Recent systematic reviews

Opioids for procedural pain in neonates.
Kinoshita M, Olsson E, Borys F, Bruschettini M
Cochrane Database Syst Rev 2023 Jun 23;6(6):CD015056. doi: 10.1002/14651858.CD015056.pub3. PMID: 37350685Free PMC Article
Techniques for preventing hypotension during spinal anaesthesia for caesarean section.
Chooi C, Cox JJ, Lumb RS, Middleton P, Chemali M, Emmett RS, Simmons SW, Cyna AM
Cochrane Database Syst Rev 2020 Jul 1;7(7):CD002251. doi: 10.1002/14651858.CD002251.pub4. PMID: 32619039Free PMC Article
Antihypertensive drug therapy for mild to moderate hypertension during pregnancy.
Abalos E, Duley L, Steyn DW, Gialdini C
Cochrane Database Syst Rev 2018 Oct 1;10(10):CD002252. doi: 10.1002/14651858.CD002252.pub4. PMID: 30277556Free PMC Article
Epidural versus non-epidural or no analgesia for pain management in labour.
Anim-Somuah M, Smyth RM, Cyna AM, Cuthbert A
Cochrane Database Syst Rev 2018 May 21;5(5):CD000331. doi: 10.1002/14651858.CD000331.pub4. PMID: 29781504Free PMC Article
Efficacy and safety of umbilical cord milking at birth: a systematic review and meta-analysis.
Al-Wassia H, Shah PS
JAMA Pediatr 2015 Jan;169(1):18-25. doi: 10.1001/jamapediatrics.2014.1906. PMID: 25365246

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