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Recurrent Cutaneous Melanoma of the Extremity

MedGen UID:
1657275
•Concept ID:
C4743980
•
Neoplastic Process
Synonyms: Recurrent Extremity Melanoma; Recurrent Melanoma of the Extremity

Definition

Cutaneous melanoma of the upper or lower extremity that has recurred after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Cutaneous Melanoma of the Extremity

Professional guidelines

PubMed

Management of the Hand Tumors.
Datta NK, Das KP, Aish PK, Datta M, Banik SK, Sen SK, Chowdhury RM
Mymensingh Med J 2023 Jan;32(1):135-143. PMID: 36594313
Management of Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma.
Crago AM, Cardona K, Koseła-Paterczyk H, Rutkowski P
Surg Oncol Clin N Am 2022 Jul;31(3):419-430. doi: 10.1016/j.soc.2022.03.006. PMID: 35715142Free PMC Article
Diagnosis and treatment of in-transit melanoma metastases.
Testori A, Ribero S, Bataille V
Eur J Surg Oncol 2017 Mar;43(3):544-560. Epub 2016 Oct 27 doi: 10.1016/j.ejso.2016.10.005. PMID: 27923593

Recent clinical studies

Etiology

Omission of Axillary Dissection Following Nodal Downstaging With Neoadjuvant Chemotherapy.
Montagna G, Mrdutt MM, Sun SX, Hlavin C, Diego EJ, Wong SM, Barrio AV, van den Bruele AB, Cabioglu N, Sevilimedu V, Rosenberger LH, Hwang ES, Ingham A, Papassotiropoulos B, Nguyen-Sträuli BD, Kurzeder C, Aybar DD, Vorburger D, Matlac DM, Ostapenko E, Riedel F, Fitzal F, Meani F, Fick F, Sagasser J, Heil J, Karanlik H, Dedes KJ, Romics L, Banys-Paluchowski M, Muslumanoglu M, Perez MDRC, Díaz MC, Heidinger M, Fehr MK, Reinisch M, Tukenmez M, Maggi N, Rocco N, Ditsch N, Gentilini OD, Paulinelli RR, Zarhi SS, Kuemmel S, Bruzas S, di Lascio S, Parissenti TK, Hoskin TL, Güth U, Ovalle V, Tausch C, Kuerer HM, Caudle AS, Boileau JF, Boughey JC, Kühn T, Morrow M, Weber WP
JAMA Oncol 2024 Jun 1;10(6):793-798. doi: 10.1001/jamaoncol.2024.0578. PMID: 38662396Free PMC Article
Management of Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma.
Crago AM, Cardona K, Koseła-Paterczyk H, Rutkowski P
Surg Oncol Clin N Am 2022 Jul;31(3):419-430. doi: 10.1016/j.soc.2022.03.006. PMID: 35715142Free PMC Article
Preoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC-62092: STRASS): a multicentre, open-label, randomised, phase 3 trial.
Bonvalot S, Gronchi A, Le Péchoux C, Swallow CJ, Strauss D, Meeus P, van Coevorden F, Stoldt S, Stoeckle E, Rutkowski P, Rastrelli M, Raut CP, Hompes D, De Paoli A, Sangalli C, Honoré C, Chung P, Miah A, Blay JY, Fiore M, Stelmes JJ, Dei Tos AP, Baldini EH, Litière S, Marreaud S, Gelderblom H, Haas RL
Lancet Oncol 2020 Oct;21(10):1366-1377. Epub 2020 Sep 14 doi: 10.1016/S1470-2045(20)30446-0. PMID: 32941794
Diagnosis and treatment of in-transit melanoma metastases.
Testori A, Ribero S, Bataille V
Eur J Surg Oncol 2017 Mar;43(3):544-560. Epub 2016 Oct 27 doi: 10.1016/j.ejso.2016.10.005. PMID: 27923593
Nail-bed melanoma.
Klausner JM, Inbar M, Gutman M, Weiss G, Skornick Y, Chaichik S, Rozin RR
J Surg Oncol 1987 Mar;34(3):208-10. doi: 10.1002/jso.2930340317. PMID: 3821128

Diagnosis

Management of Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma.
Crago AM, Cardona K, Koseła-Paterczyk H, Rutkowski P
Surg Oncol Clin N Am 2022 Jul;31(3):419-430. doi: 10.1016/j.soc.2022.03.006. PMID: 35715142Free PMC Article
Subungual Melanoma of the Hand.
Chakera AH, Quinn MJ, Lo S, Drummond M, Haydu LE, Bond JS, Stretch JR, Saw RPM, Lee KJ, McCarthy WH, Scolyer RA, Thompson JF
Ann Surg Oncol 2019 Apr;26(4):1035-1043. Epub 2018 Dec 18 doi: 10.1245/s10434-018-07094-w. PMID: 30565042
Diagnosis and treatment of in-transit melanoma metastases.
Testori A, Ribero S, Bataille V
Eur J Surg Oncol 2017 Mar;43(3):544-560. Epub 2016 Oct 27 doi: 10.1016/j.ejso.2016.10.005. PMID: 27923593
Nail-bed melanoma.
Klausner JM, Inbar M, Gutman M, Weiss G, Skornick Y, Chaichik S, Rozin RR
J Surg Oncol 1987 Mar;34(3):208-10. doi: 10.1002/jso.2930340317. PMID: 3821128
Aponeurotic sarcoma.
Laskowski J
Pol Med J 1971;10(1):12-7. PMID: 5573897

Therapy

Preoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC-62092: STRASS): a multicentre, open-label, randomised, phase 3 trial.
Bonvalot S, Gronchi A, Le Péchoux C, Swallow CJ, Strauss D, Meeus P, van Coevorden F, Stoldt S, Stoeckle E, Rutkowski P, Rastrelli M, Raut CP, Hompes D, De Paoli A, Sangalli C, Honoré C, Chung P, Miah A, Blay JY, Fiore M, Stelmes JJ, Dei Tos AP, Baldini EH, Litière S, Marreaud S, Gelderblom H, Haas RL
Lancet Oncol 2020 Oct;21(10):1366-1377. Epub 2020 Sep 14 doi: 10.1016/S1470-2045(20)30446-0. PMID: 32941794
Diagnosis and treatment of in-transit melanoma metastases.
Testori A, Ribero S, Bataille V
Eur J Surg Oncol 2017 Mar;43(3):544-560. Epub 2016 Oct 27 doi: 10.1016/j.ejso.2016.10.005. PMID: 27923593
The role of regional chemotherapy in the management of extremity soft tissue malignancies.
Smith HG, Hayes AJ
Eur J Surg Oncol 2016 Jan;42(1):7-17. Epub 2015 Sep 4 doi: 10.1016/j.ejso.2015.08.165. PMID: 26382102
Topical imiquimod in the treatment of metastatic melanoma to skin.
Wolf IH, Smolle J, Binder B, Cerroni L, Richtig E, Kerl H
Arch Dermatol 2003 Mar;139(3):273-6. doi: 10.1001/archderm.139.3.273. PMID: 12622616
Tumors of the nail.
Salasche SJ, Garland LD
Dermatol Clin 1985 Jul;3(3):501-19. PMID: 3006954

Prognosis

Management of the Hand Tumors.
Datta NK, Das KP, Aish PK, Datta M, Banik SK, Sen SK, Chowdhury RM
Mymensingh Med J 2023 Jan;32(1):135-143. PMID: 36594313
Subungual Melanoma of the Hand.
Chakera AH, Quinn MJ, Lo S, Drummond M, Haydu LE, Bond JS, Stretch JR, Saw RPM, Lee KJ, McCarthy WH, Scolyer RA, Thompson JF
Ann Surg Oncol 2019 Apr;26(4):1035-1043. Epub 2018 Dec 18 doi: 10.1245/s10434-018-07094-w. PMID: 30565042
The role of regional chemotherapy in the management of extremity soft tissue malignancies.
Smith HG, Hayes AJ
Eur J Surg Oncol 2016 Jan;42(1):7-17. Epub 2015 Sep 4 doi: 10.1016/j.ejso.2015.08.165. PMID: 26382102
Nail-bed melanoma.
Klausner JM, Inbar M, Gutman M, Weiss G, Skornick Y, Chaichik S, Rozin RR
J Surg Oncol 1987 Mar;34(3):208-10. doi: 10.1002/jso.2930340317. PMID: 3821128
MELANOMA OF THE EXTREMITIES; EXPERIENCES WITH CONVENTIONAL TREATMENT AND PERFUSION IN 339 CASES.
STEHLIN JS Jr, CLARK RL
Am J Surg 1965 Sep;110:366-83. doi: 10.1016/0002-9610(65)90076-0. PMID: 14337993

Clinical prediction guides

Current Controversies in Melanoma Treatment.
Temple-Oberle C, Nicholas C, Rojas-Garcia P
Plast Reconstr Surg 2023 Mar 1;151(3):495e-505e. Epub 2023 Feb 23 doi: 10.1097/PRS.0000000000009936. PMID: 36821575
Management of Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma.
Crago AM, Cardona K, Koseła-Paterczyk H, Rutkowski P
Surg Oncol Clin N Am 2022 Jul;31(3):419-430. doi: 10.1016/j.soc.2022.03.006. PMID: 35715142Free PMC Article
Morbidity and Mortality of Melanoma on the Trunk and Extremities Treated With Mohs Surgery Versus Wide Excision: A Systematic Review.
Bednar ED, Zon M, Abu-Hilal M
Dermatol Surg 2022 Jan 1;48(1):1-6. doi: 10.1097/DSS.0000000000003250. PMID: 34608076
Preoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC-62092: STRASS): a multicentre, open-label, randomised, phase 3 trial.
Bonvalot S, Gronchi A, Le Péchoux C, Swallow CJ, Strauss D, Meeus P, van Coevorden F, Stoldt S, Stoeckle E, Rutkowski P, Rastrelli M, Raut CP, Hompes D, De Paoli A, Sangalli C, Honoré C, Chung P, Miah A, Blay JY, Fiore M, Stelmes JJ, Dei Tos AP, Baldini EH, Litière S, Marreaud S, Gelderblom H, Haas RL
Lancet Oncol 2020 Oct;21(10):1366-1377. Epub 2020 Sep 14 doi: 10.1016/S1470-2045(20)30446-0. PMID: 32941794
Subungual Melanoma of the Hand.
Chakera AH, Quinn MJ, Lo S, Drummond M, Haydu LE, Bond JS, Stretch JR, Saw RPM, Lee KJ, McCarthy WH, Scolyer RA, Thompson JF
Ann Surg Oncol 2019 Apr;26(4):1035-1043. Epub 2018 Dec 18 doi: 10.1245/s10434-018-07094-w. PMID: 30565042

Recent systematic reviews

Metastases to the nail unit and distal phalanx: a systematic review.
Curtis KL, Lipner SR
Arch Dermatol Res 2023 Apr;315(3):347-358. Epub 2022 Oct 19 doi: 10.1007/s00403-022-02411-6. PMID: 36260150
Morbidity and Mortality of Melanoma on the Trunk and Extremities Treated With Mohs Surgery Versus Wide Excision: A Systematic Review.
Bednar ED, Zon M, Abu-Hilal M
Dermatol Surg 2022 Jan 1;48(1):1-6. doi: 10.1097/DSS.0000000000003250. PMID: 34608076
Isolated limb perfusion in Merkel cell carcinoma offers high rate of complete response and durable local-regional control: Systematic review and institutional experience.
Thiels CA, Gonzalez AB, Gray RJ, Jakub JW
J Surg Oncol 2016 Aug;114(2):187-92. Epub 2016 May 18 doi: 10.1002/jso.24289. PMID: 27189050
Accuracy of sentinel lymph node biopsy in large and multifocal/multicentric breast carcinoma--a systematic review.
Spillane AJ, Brennan ME
Eur J Surg Oncol 2011 May;37(5):371-85. Epub 2011 Feb 3 doi: 10.1016/j.ejso.2011.01.011. PMID: 21292433
Optimal excision margins for primary cutaneous melanoma: a systematic review and meta-analysis.
Haigh PI, DiFronzo LA, McCready DR
Can J Surg 2003 Dec;46(6):419-26. PMID: 14680348Free PMC Article

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