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Recurrent Anal Adenocarcinoma

MedGen UID:
1662871
•Concept ID:
C4727363
•
Neoplastic Process

Definition

The reemergence of anal adenocarcinoma after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Anal Adenocarcinoma

Professional guidelines

PubMed

Rectal cancer lexicon 2023 revised and updated consensus statement from the Society of Abdominal Radiology Colorectal and Anal Cancer Disease-Focused Panel.
Lee S, Kassam Z, Baheti AD, Hope TA, Chang KJ, Korngold EK, Taggart MW, Horvat N
Abdom Radiol (NY) 2023 Sep;48(9):2792-2806. Epub 2023 May 5 doi: 10.1007/s00261-023-03893-2. PMID: 37145311Free PMC Article
Neuroendocrine Carcinoma of the Anus and Rectum: Patient Characteristics and Treatment Options.
Ueberroth BE, Liu AJ, Starr JS, Hobday TJ, Ashman JB, Mishra N, Bekaii-Saab TS, Halfdanarson TR, Sonbol MB
Clin Colorectal Cancer 2021 Jun;20(2):e139-e149. Epub 2020 Dec 17 doi: 10.1016/j.clcc.2020.12.001. PMID: 33551318
Survival Outcomes After Initial Treatment for Anal Adenocarcinoma: A Population-Based Cohort Study.
Park H
Clin Colorectal Cancer 2020 Sep;19(3):e75-e82. Epub 2020 Apr 13 doi: 10.1016/j.clcc.2020.04.001. PMID: 32389595

Recent clinical studies

Etiology

Assessment of a Watch-and-Wait Strategy for Rectal Cancer in Patients With a Complete Response After Neoadjuvant Therapy.
Smith JJ, Strombom P, Chow OS, Roxburgh CS, Lynn P, Eaton A, Widmar M, Ganesh K, Yaeger R, Cercek A, Weiser MR, Nash GM, Guillem JG, Temple LKF, Chalasani SB, Fuqua JL, Petkovska I, Wu AJ, Reyngold M, Vakiani E, Shia J, Segal NH, Smith JD, Crane C, Gollub MJ, Gonen M, Saltz LB, Garcia-Aguilar J, Paty PB
JAMA Oncol 2019 Apr 1;5(4):e185896. Epub 2019 Apr 11 doi: 10.1001/jamaoncol.2018.5896. PMID: 30629084Free PMC Article
What is the impact of neoadjuvant chemoradiation on outcomes in gastro-intestinal cancer?
Mariette C, Brouquet A, Tzanis D, Laurenzi A, de la Rochefordière A, Mariani P, Piessen G, Sa Cunha A, Penna C
J Visc Surg 2017 Jun;154(3):185-195. Epub 2017 Jun 9 doi: 10.1016/j.jviscsurg.2017.05.004. PMID: 28602545
Prospective Validation of a Low Rectal Cancer Magnetic Resonance Imaging Staging System and Development of a Local Recurrence Risk Stratification Model: The MERCURY II Study.
Battersby NJ, How P, Moran B, Stelzner S, West NP, Branagan G, Strassburg J, Quirke P, Tekkis P, Pedersen BG, Gudgeon M, Heald B, Brown G; MERCURY II Study Group
Ann Surg 2016 Apr;263(4):751-60. doi: 10.1097/SLA.0000000000001193. PMID: 25822672
Low rectal cancer: classification and standardization of surgery.
Rullier E, Denost Q, Vendrely V, Rullier A, Laurent C
Dis Colon Rectum 2013 May;56(5):560-7. doi: 10.1097/DCR.0b013e31827c4a8c. PMID: 23575394
Randomized trial of short-course radiotherapy versus long-course chemoradiation comparing rates of local recurrence in patients with T3 rectal cancer: Trans-Tasman Radiation Oncology Group trial 01.04.
Ngan SY, Burmeister B, Fisher RJ, Solomon M, Goldstein D, Joseph D, Ackland SP, Schache D, McClure B, McLachlan SA, McKendrick J, Leong T, Hartopeanu C, Zalcberg J, Mackay J
J Clin Oncol 2012 Nov 1;30(31):3827-33. Epub 2012 Sep 24 doi: 10.1200/JCO.2012.42.9597. PMID: 23008301

Diagnosis

Rectal cancer lexicon 2023 revised and updated consensus statement from the Society of Abdominal Radiology Colorectal and Anal Cancer Disease-Focused Panel.
Lee S, Kassam Z, Baheti AD, Hope TA, Chang KJ, Korngold EK, Taggart MW, Horvat N
Abdom Radiol (NY) 2023 Sep;48(9):2792-2806. Epub 2023 May 5 doi: 10.1007/s00261-023-03893-2. PMID: 37145311Free PMC Article
Perianal Paget's-an aggressive disease.
Rudnicki Y, Stapleton SM, Batra R, Gan T, Mathis KL, Kelley SR
Colorectal Dis 2023 Jun;25(6):1213-1221. Epub 2023 Mar 21 doi: 10.1111/codi.16549. PMID: 36945125
Assessment of a Watch-and-Wait Strategy for Rectal Cancer in Patients With a Complete Response After Neoadjuvant Therapy.
Smith JJ, Strombom P, Chow OS, Roxburgh CS, Lynn P, Eaton A, Widmar M, Ganesh K, Yaeger R, Cercek A, Weiser MR, Nash GM, Guillem JG, Temple LKF, Chalasani SB, Fuqua JL, Petkovska I, Wu AJ, Reyngold M, Vakiani E, Shia J, Segal NH, Smith JD, Crane C, Gollub MJ, Gonen M, Saltz LB, Garcia-Aguilar J, Paty PB
JAMA Oncol 2019 Apr 1;5(4):e185896. Epub 2019 Apr 11 doi: 10.1001/jamaoncol.2018.5896. PMID: 30629084Free PMC Article
Synchronous quintuple primary gastrointestinal tract malignancies: Case report.
Kim SH, Park BS, Kim HS, Kim JH
World J Gastroenterol 2017 Jan 7;23(1):173-177. doi: 10.3748/wjg.v23.i1.173. PMID: 28104993Free PMC Article
Anal neoplasms.
Garrett K, Kalady MF
Surg Clin North Am 2010 Feb;90(1):147-61, Table of Contents. doi: 10.1016/j.suc.2009.09.008. PMID: 20109639

Therapy

Organ Preservation and Survival by Clinical Response Grade in Patients With Rectal Cancer Treated With Total Neoadjuvant Therapy: A Secondary Analysis of the OPRA Randomized Clinical Trial.
Thompson HM, Omer DM, Lin S, Kim JK, Yuval JB, Verheij FS, Qin LX, Gollub MJ, Wu AJ, Lee M, Patil S, Hezel AF, Marcet JE, Cataldo PA, Polite BN, Herzig DO, Liska D, Oommen S, Friel CM, Ternent CA, Coveler AL, Hunt SR, Garcia-Aguilar J; OPRA Consortium
JAMA Netw Open 2024 Jan 2;7(1):e2350903. doi: 10.1001/jamanetworkopen.2023.50903. PMID: 38194231Free PMC Article
Robotic versus laparoscopic surgery for middle and low rectal cancer (REAL): short-term outcomes of a multicentre randomised controlled trial.
Feng Q, Yuan W, Li T, Tang B, Jia B, Zhou Y, Zhang W, Zhao R, Zhang C, Cheng L, Zhang X, Liang F, He G, Wei Y, Xu J; REAL Study Group
Lancet Gastroenterol Hepatol 2022 Nov;7(11):991-1004. Epub 2022 Sep 8 doi: 10.1016/S2468-1253(22)00248-5. PMID: 36087608
Adenocarcinoma of the anal canal - a systematic review.
Anwar S, Welbourn H, Hill J, Sebag-Montefiore D
Colorectal Dis 2013 Dec;15(12):1481-8. doi: 10.1111/codi.12325. PMID: 23809885
Randomized trial of short-course radiotherapy versus long-course chemoradiation comparing rates of local recurrence in patients with T3 rectal cancer: Trans-Tasman Radiation Oncology Group trial 01.04.
Ngan SY, Burmeister B, Fisher RJ, Solomon M, Goldstein D, Joseph D, Ackland SP, Schache D, McClure B, McLachlan SA, McKendrick J, Leong T, Hartopeanu C, Zalcberg J, Mackay J
J Clin Oncol 2012 Nov 1;30(31):3827-33. Epub 2012 Sep 24 doi: 10.1200/JCO.2012.42.9597. PMID: 23008301
Malignant anal tumours.
Deans GT, McAleer JJ, Spence RA
Br J Surg 1994 Apr;81(4):500-8. doi: 10.1002/bjs.1800810405. PMID: 8205420

Prognosis

Adenocarcinoma of the anal canal - a systematic review.
Anwar S, Welbourn H, Hill J, Sebag-Montefiore D
Colorectal Dis 2013 Dec;15(12):1481-8. doi: 10.1111/codi.12325. PMID: 23809885
Low rectal cancer: classification and standardization of surgery.
Rullier E, Denost Q, Vendrely V, Rullier A, Laurent C
Dis Colon Rectum 2013 May;56(5):560-7. doi: 10.1097/DCR.0b013e31827c4a8c. PMID: 23575394
Randomized trial of short-course radiotherapy versus long-course chemoradiation comparing rates of local recurrence in patients with T3 rectal cancer: Trans-Tasman Radiation Oncology Group trial 01.04.
Ngan SY, Burmeister B, Fisher RJ, Solomon M, Goldstein D, Joseph D, Ackland SP, Schache D, McClure B, McLachlan SA, McKendrick J, Leong T, Hartopeanu C, Zalcberg J, Mackay J
J Clin Oncol 2012 Nov 1;30(31):3827-33. Epub 2012 Sep 24 doi: 10.1200/JCO.2012.42.9597. PMID: 23008301
Anal neoplasms.
Garrett K, Kalady MF
Surg Clin North Am 2010 Feb;90(1):147-61, Table of Contents. doi: 10.1016/j.suc.2009.09.008. PMID: 20109639
Malignant anal tumours.
Deans GT, McAleer JJ, Spence RA
Br J Surg 1994 Apr;81(4):500-8. doi: 10.1002/bjs.1800810405. PMID: 8205420

Clinical prediction guides

Perianal Paget's-an aggressive disease.
Rudnicki Y, Stapleton SM, Batra R, Gan T, Mathis KL, Kelley SR
Colorectal Dis 2023 Jun;25(6):1213-1221. Epub 2023 Mar 21 doi: 10.1111/codi.16549. PMID: 36945125
Assessment of a Watch-and-Wait Strategy for Rectal Cancer in Patients With a Complete Response After Neoadjuvant Therapy.
Smith JJ, Strombom P, Chow OS, Roxburgh CS, Lynn P, Eaton A, Widmar M, Ganesh K, Yaeger R, Cercek A, Weiser MR, Nash GM, Guillem JG, Temple LKF, Chalasani SB, Fuqua JL, Petkovska I, Wu AJ, Reyngold M, Vakiani E, Shia J, Segal NH, Smith JD, Crane C, Gollub MJ, Gonen M, Saltz LB, Garcia-Aguilar J, Paty PB
JAMA Oncol 2019 Apr 1;5(4):e185896. Epub 2019 Apr 11 doi: 10.1001/jamaoncol.2018.5896. PMID: 30629084Free PMC Article
Prospective Validation of a Low Rectal Cancer Magnetic Resonance Imaging Staging System and Development of a Local Recurrence Risk Stratification Model: The MERCURY II Study.
Battersby NJ, How P, Moran B, Stelzner S, West NP, Branagan G, Strassburg J, Quirke P, Tekkis P, Pedersen BG, Gudgeon M, Heald B, Brown G; MERCURY II Study Group
Ann Surg 2016 Apr;263(4):751-60. doi: 10.1097/SLA.0000000000001193. PMID: 25822672
Adenocarcinoma of the anal canal - a systematic review.
Anwar S, Welbourn H, Hill J, Sebag-Montefiore D
Colorectal Dis 2013 Dec;15(12):1481-8. doi: 10.1111/codi.12325. PMID: 23809885
Low rectal cancer: classification and standardization of surgery.
Rullier E, Denost Q, Vendrely V, Rullier A, Laurent C
Dis Colon Rectum 2013 May;56(5):560-7. doi: 10.1097/DCR.0b013e31827c4a8c. PMID: 23575394

Recent systematic reviews

Perianal Mucinous Adenocarcinoma: A Case Report and a Systematic Review of the Literature.
Gkegkes ID, Milionis V, Goutas N, Mantzoros I, Bourtzinakou AA, Stamatiadis AP
J Gastrointest Cancer 2024 Oct 18;56(1):6. doi: 10.1007/s12029-024-01116-5. PMID: 39422801
Non-mucinous adenocarcinomas and squamous cell carcinomas of the anal region masquerading as abscess or fistula: a retrospective analysis and systematic review of literature.
Tekbaş A, Mothes H, Settmacher U, Schuele S
J Cancer Res Clin Oncol 2022 Jun;148(6):1509-1522. Epub 2021 Aug 2 doi: 10.1007/s00432-021-03747-8. PMID: 34338860Free PMC Article
Transanal Minimally Invasive Surgery (TAMIS) for Rectal Lesions: A Systematic Review.
Hong KD, Kang S, Urn JW, Lee SI
Hepatogastroenterology 2015 Jun;62(140):863-7. PMID: 26902017
Adenocarcinoma of the anal canal - a systematic review.
Anwar S, Welbourn H, Hill J, Sebag-Montefiore D
Colorectal Dis 2013 Dec;15(12):1481-8. doi: 10.1111/codi.12325. PMID: 23809885
Effectiveness of photodynamic therapy for mammary and extra-mammary Paget's disease: a state of the science review.
Nardelli AA, Stafinski T, Menon D
BMC Dermatol 2011 Jun 15;11:13. doi: 10.1186/1471-5945-11-13. PMID: 21676258Free PMC Article

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