U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Pituitary Gland Non-Hodgkin Lymphoma

MedGen UID:
1663782
•Concept ID:
C4744383
•
Neoplastic Process
Synonym: Primary Pituitary Gland Non-Hodgkin Lymphoma

Definition

A rare non-Hodgkin lymphoma that arises from the pituitary gland. The majority are diffuse large B-cell lymphomas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPituitary Gland Non-Hodgkin Lymphoma

Professional guidelines

PubMed

Prospective study on the influence of disease or treatment on pituitary function in 31 children with acute leukemia and non-Hodgkin's lymphoma.
Mittler U, Mohnike K, Kluba U, Kröning G, Kapitza W, Aumann V, Röppnack R
Haematol Blood Transfus 1990;33:571-6. doi: 10.1007/978-3-642-74643-7_104. PMID: 2323657

Recent clinical studies

Etiology

Epidemiology of Cancer Among Chronic Kidney Disease Patients Compared to The General Population.
Atris A, Al Salmi I, Al Rahbi F, Al-Bahrani BJ, Hannawi S
Gulf J Oncolog 2022 May;1(39):7-15. PMID: 35695340
Hypothyroidism after Radiation Therapy for Childhood Cancer: A Report from the Childhood Cancer Survivor Study.
Inskip PD, Veiga LHS, Brenner AV, Sigurdson AJ, Ostroumova E, Chow EJ, Stovall M, Smith SA, Weathers RE, Leisenring W, Robison LL, Armstrong GT, Sklar CA, Lubin JH
Radiat Res 2018 Aug;190(2):117-132. Epub 2018 May 15 doi: 10.1667/RR14888.1. PMID: 29763379Free PMC Article
The incidence of secondary central nervous system involvement in patients with non-Hodgkin's lymphoma as detected by 18F-FDG PET/CT.
Akkas BE, Vural GU
Nucl Med Commun 2013 Jan;34(1):50-6. doi: 10.1097/MNM.0b013e32835aaa48. PMID: 23111376
Familial blood vessel tumors and subsequent cancers.
Ji J, Hemminki K
Ann Oncol 2007 Jul;18(7):1260-7. Epub 2007 Apr 10 doi: 10.1093/annonc/mdm092. PMID: 17426058
Cancer incidence after nasopharyngeal radium irradiation.
Ronckers CM, Van Leeuwen FE, Hayes RB, Verduijn PG, Stovall M, Land CE
Epidemiology 2002 Sep;13(5):552-60. doi: 10.1097/00001648-200209000-00011. PMID: 12192225

Diagnosis

Concomitant Primary CNS Lymphoma and FSH-Pituitary Adenoma Arising Within the Sella. Entirely Coincidental?
Ban VS, Chaudhary BR, Allinson K, Santarius T, Kirollos RW
Neurosurgery 2017 Jan 1;80(1):E170-E175. doi: 10.1093/neuros/nyw003. PMID: 28362886Free PMC Article
Pituitary lymphoma developing within pituitary adenoma.
Morita K, Nakamura F, Kamikubo Y, Mizuno N, Miyauchi M, Yamamoto G, Nannya Y, Ichikawa M, Kurokawa M
Int J Hematol 2012 Jun;95(6):721-4. Epub 2012 Apr 21 doi: 10.1007/s12185-012-1075-0. PMID: 22527852
T-cell lymphoblastic lymphoma/leukemia presenting as a pituitary mass lesion: a case report and review of the literature.
Wiens AL, Hagen MC, Bonnin JM, Rizzo KA
Neuropathology 2012 Dec;32(6):668-74. Epub 2012 Mar 21 doi: 10.1111/j.1440-1789.2012.01314.x. PMID: 22432597
Sellar and parasellar intravascular lymphoma mimicking pituitary apoplexy.
Rizek P, Seitelbach M, Alturkustani M, Leung A, Fraser JA
J Neuroophthalmol 2012 Mar;32(1):33-7. doi: 10.1097/WNO.0b013e31823f457e. PMID: 22173269
Pituitary lymphoma: a case report and literature review.
Mathiasen RA, Jarrahy R, Cha ST, Kovacs K, Herman VS, Ginsberg E, Shahinian HK
Pituitary 2000 May;2(4):283-7. doi: 10.1023/a:1009969417380. PMID: 11081150

Therapy

FDG-PET/CT is a pivotal imaging modality to diagnose rare intravascular large B-cell lymphoma: case report and review of literature.
Colavolpe C, Ebbo M, Trousse D, Khibri H, Franques J, Chetaille B, Coso D, Ouvrier MJ, Gastaud L, Guedj E, Schleinitz N
Hematol Oncol 2015 Jun;33(2):99-109. Epub 2014 May 21 doi: 10.1002/hon.2140. PMID: 24850057
Diffuse large cell non-Hodgkin lymphoma with pituitary and bilateral adrenal involvement.
Wang XL, Lü ZH, Mu YM, Dou JT, Lu JM, Zhong WW, Pan CY
Intern Med J 2012 Mar;42(3):329-32. doi: 10.1111/j.1445-5994.2011.02691.x. PMID: 22432986
Pituitary stalk thickening and primary central nervous system lymphoma.
Capra M, Wherrett D, Weitzman S, Dirks P, Hawkins C, Bouffet E
J Neurooncol 2004 Mar-Apr;67(1-2):227-31. doi: 10.1023/b:neon.0000021863.06620.48. PMID: 15072472
Therapy-related megakaryoblastic leukemia with pituitary involvement following treatment for non-Hodgkin's lymphoma.
Saitoh T, Morimoto K, Kumagai T, Saiki M, Tanaka M, Aikawa S, Tsuboi I, Sawada U, Horie T
Intern Med 1999 Nov;38(11):904-9. doi: 10.2169/internalmedicine.38.904. PMID: 10563755
Pituitary function in patients receiving intermittent cytotoxic and corticosteroid therapy for malignant lymphoma.
Naysmith A, Hancock BW, Cullen DR, Richmond J, Wilde CE
Lancet 1976 Apr 3;1(7962):715-7. doi: 10.1016/s0140-6736(76)93090-7. PMID: 56533

Prognosis

Concomitant Primary CNS Lymphoma and FSH-Pituitary Adenoma Arising Within the Sella. Entirely Coincidental?
Ban VS, Chaudhary BR, Allinson K, Santarius T, Kirollos RW
Neurosurgery 2017 Jan 1;80(1):E170-E175. doi: 10.1093/neuros/nyw003. PMID: 28362886Free PMC Article
Diffuse large cell non-Hodgkin lymphoma with pituitary and bilateral adrenal involvement.
Wang XL, Lü ZH, Mu YM, Dou JT, Lu JM, Zhong WW, Pan CY
Intern Med J 2012 Mar;42(3):329-32. doi: 10.1111/j.1445-5994.2011.02691.x. PMID: 22432986
Extranodal NK/T-cell lymphoma presenting as a pituitary mass. Case report and review of the literature.
Liu JK, Sayama C, Chin SS, Couldwell WT
J Neurosurg 2007 Sep;107(3):660-5. doi: 10.3171/JNS-07/09/0660. PMID: 17886569
Familial blood vessel tumors and subsequent cancers.
Ji J, Hemminki K
Ann Oncol 2007 Jul;18(7):1260-7. Epub 2007 Apr 10 doi: 10.1093/annonc/mdm092. PMID: 17426058
Lymphoma metastasizing to the pituitary: an unusual presentation of a treatable disease.
Megan Ogilvie C, Payne S, Evanson J, Lister TA, Grossman AB
Pituitary 2005;8(2):139-46. doi: 10.1007/s11102-005-4535-1. PMID: 16379034

Clinical prediction guides

Intravascular large B-cell lymphoma causing hypopituitarism and respiratory failure due to infiltration into pulmonary capillaries.
Kosaka T, Honda Y, Homma Y, Nakata M
BMJ Case Rep 2022 May 24;15(5) doi: 10.1136/bcr-2021-247880. PMID: 35609931Free PMC Article
Hypothyroidism after Radiation Therapy for Childhood Cancer: A Report from the Childhood Cancer Survivor Study.
Inskip PD, Veiga LHS, Brenner AV, Sigurdson AJ, Ostroumova E, Chow EJ, Stovall M, Smith SA, Weathers RE, Leisenring W, Robison LL, Armstrong GT, Sklar CA, Lubin JH
Radiat Res 2018 Aug;190(2):117-132. Epub 2018 May 15 doi: 10.1667/RR14888.1. PMID: 29763379Free PMC Article
Variability in the expression of polycomb proteins in different normal and tumoral tissues. A pilot study using tissue microarrays.
Sánchez-Beato M, Sánchez E, González-Carreró J, Morente M, Díez A, Sánchez-Verde L, Martín MC, Cigudosa JC, Vidal M, Piris MA
Mod Pathol 2006 May;19(5):684-94. doi: 10.1038/modpathol.3800577. PMID: 16528373
Cancer incidence after nasopharyngeal radium irradiation.
Ronckers CM, Van Leeuwen FE, Hayes RB, Verduijn PG, Stovall M, Land CE
Epidemiology 2002 Sep;13(5):552-60. doi: 10.1097/00001648-200209000-00011. PMID: 12192225
Growth retardation in childhood leukemia and lymphoma. Special reference to patients with CNS relapse.
Yamada S, Ishii E, Okabe Y, Kai T, Kuroiwa T, Hasuo K, Akazawa K, Tasaka H, Ueda K
Am J Pediatr Hematol Oncol 1992 Aug;14(3):236-40. doi: 10.1097/00043426-199208000-00010. PMID: 1510194

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...