U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Hypoplasia of maxilla relative to mandible

MedGen UID:
1671064
•Concept ID:
C4732856
•
Congenital Abnormality
Synonym: Disorder of maxillary and mandibular dental arch relationship
 
HPO: HP:0410218

Definition

Abnormally small dimension of the maxilla (upper jaw) relative to the mandible (lower jaw). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHypoplasia of maxilla relative to mandible

Professional guidelines

PubMed

Craniofacial microsomia: goals of treatment, staged reconstruction and long-term outcome.
Chowchuen B, Pisek P, Chowchuen P, Thanaviratananich S
J Med Assoc Thai 2011 Dec;94 Suppl 6:S100-8. PMID: 22423423

Recent clinical studies

Etiology

Prevalence and Distribution of Dental Anomalies in Schoolchildren in Kuwait.
Alanzi A, Bufersen N, Haider S, Abdulrahim M
Int Dent J 2024 Jun;74(3):566-572. Epub 2024 Jan 29 doi: 10.1016/j.identj.2023.10.019. PMID: 38290916Free PMC Article
What to Expect of Feeding Abilities and Nutritional Aspects in Achondroplasia Patients: A Narrative Review.
Sforza E, Margiotta G, Giorgio V, Limongelli D, Proli F, Kuczynska EM, Leoni C, De Rose C, Trevisan V, Romeo DM, Calandrelli R, De Corso E, Massimi L, Palmacci O, Rigante D, Zampino G, Onesimo R
Genes (Basel) 2023 Jan 12;14(1) doi: 10.3390/genes14010199. PMID: 36672940Free PMC Article
Lipofilling as refinement procedure in maxillo-mandibular malformations.
Cervelli D, Gasparini G, Moro A, Pelo S, Foresta E, Grussu F, D'Amato G, De Angelis P, Saponaro G
Acta Otorhinolaryngol Ital 2016 Oct;36(5):368-372. doi: 10.14639/0392-100X-857. PMID: 27958596Free PMC Article
Is Counterclockwise Rotation of the Maxillomandibular Complex Stable Compared With Clockwise Rotation in the Correction of Dentofacial Deformities? A Systematic Review and Meta-Analysis.
Al-Moraissi EA, Wolford LM
J Oral Maxillofac Surg 2016 Oct;74(10):2066.e1-2066.e12. Epub 2016 Jun 11 doi: 10.1016/j.joms.2016.06.001. PMID: 27371873
Spectrum of Dental Phenotypes in Nonsyndromic Orofacial Clefting.
Howe BJ, Cooper ME, Vieira AR, Weinberg SM, Resick JM, Nidey NL, Wehby GL, Marazita ML, Moreno Uribe LM
J Dent Res 2015 Jul;94(7):905-12. doi: 10.1177/0022034515588281. PMID: 26082386Free PMC Article

Diagnosis

Loeys-Dietz and Shprintzen-Goldberg syndromes: analysis of TGF-β-opathies with craniofacial manifestations using an innovative multimodality method.
Almpani K, Liberton DK, Jani P, Keyvanfar C, Mishra R, Curry N, Orzechowski P, Frischmeyer-Guerrerio PA, Lee JS
J Med Genet 2022 Oct;59(10):938-946. Epub 2021 Dec 16 doi: 10.1136/jmedgenet-2021-107695. PMID: 34916229Free PMC Article
SH3BP2-related fibro-osseous disorders of the maxilla and mandible: A systematic review.
Kueper J, Tsimbal C, Olsen BR, Kaban L, Liao EC
Int J Oral Maxillofac Surg 2022 Jan;51(1):54-61. Epub 2021 Apr 30 doi: 10.1016/j.ijom.2021.04.001. PMID: 33941395
Molecular Basis for Craniofacial Phenotypes Caused by Sclerostin Deletion.
Chen J, Yuan X, Pilawski I, Liu X, Delgado-Calle J, Bellido T, Turkkahraman H, Helms JA
J Dent Res 2021 Mar;100(3):310-317. Epub 2020 Oct 20 doi: 10.1177/0022034520963584. PMID: 33078679Free PMC Article
Binder syndrome.
Chummun S, McLean NR, Nugent M, Anderson PJ, David DJ
J Craniofac Surg 2012 Jul;23(4):986-90. doi: 10.1097/SCS.0b013e31824e2683. PMID: 22777437
Crouzonodermoskeletal syndrome.
Jeftha A, Stephen L, Morkel JA, Beighton P
J Clin Pediatr Dent 2004 Winter;28(2):173-6. doi: 10.17796/jcpd.28.2.72m01l5g50448548. PMID: 14969379

Therapy

Ultrasonographic study of fetal facial profile markers during the first trimester.
Ji C, Jiang X, Yin L, Deng X, Yang Z, Pan Q, Zhang J, Liang Q
BMC Pregnancy Childbirth 2021 Apr 24;21(1):324. doi: 10.1186/s12884-021-03813-6. PMID: 33894762Free PMC Article
Prevalence of MIH in children aged 12 to 15 years in Beijing, China.
Yi X, Chen W, Liu M, Zhang H, Hou W, Wang Y
Clin Oral Investig 2021 Jan;25(1):355-361. Epub 2020 Sep 2 doi: 10.1007/s00784-020-03546-4. PMID: 32876747
Is Counterclockwise Rotation of the Maxillomandibular Complex Stable Compared With Clockwise Rotation in the Correction of Dentofacial Deformities? A Systematic Review and Meta-Analysis.
Al-Moraissi EA, Wolford LM
J Oral Maxillofac Surg 2016 Oct;74(10):2066.e1-2066.e12. Epub 2016 Jun 11 doi: 10.1016/j.joms.2016.06.001. PMID: 27371873
Treatment outcomes of orthodontic treatment, corticotomy-assisted orthodontic treatment, and anterior segmental osteotomy for bimaxillary dentoalveolar protrusion.
Lee JK, Chung KR, Baek SH
Plast Reconstr Surg 2007 Sep 15;120(4):1027-1036. doi: 10.1097/01.prs.0000277999.01337.8b. PMID: 17805132
Mandibular and maxillary asymmetry in individuals with unilateral cleft lip and palate.
Laspos CP, Kyrkanides S, Tallents RH, Moss ME, Subtelny JD
Cleft Palate Craniofac J 1997 May;34(3):232-9. doi: 10.1597/1545-1569_1997_034_0232_mamaii_2.3.co_2. PMID: 9167074

Prognosis

SH3BP2-related fibro-osseous disorders of the maxilla and mandible: A systematic review.
Kueper J, Tsimbal C, Olsen BR, Kaban L, Liao EC
Int J Oral Maxillofac Surg 2022 Jan;51(1):54-61. Epub 2021 Apr 30 doi: 10.1016/j.ijom.2021.04.001. PMID: 33941395
Treacher Collins syndrome: A novel TCOF1 mutation and monopodial stapes.
Kantaputra PN, Tripuwabhrut K, Intachai W, Carlson BM, Quarto N, Ngamphiw C, Tongsima S, Sonsuwan N
Clin Otolaryngol 2020 Sep;45(5):695-702. Epub 2020 May 25 doi: 10.1111/coa.13560. PMID: 32351010
Clinical and Molecular Study of ELMO-2-Related Massive Intraosseous Vascular Malformations: Lessons Learned From 25 Years of Follow-up.
Vargel I, Calis M, Canter HI, Cil BE
Ann Plast Surg 2019 Sep;83(3):293-299. doi: 10.1097/SAP.0000000000001786. PMID: 30882408
Craniofacial cephalometric morphology in 8-year-old children with operated sagittal synostosis.
Heliövaara A, Vuola P, Hukki J
Orthod Craniofac Res 2015 Feb;18(1):27-32. Epub 2014 Sep 29 doi: 10.1111/ocr.12056. PMID: 25264570
Hypodontia prevalence and pattern in women with epithelial ovarian cancer.
Fekonja A, Čretnik A, Takač I
Angle Orthod 2014 Sep;84(5):810-4. Epub 2014 Apr 1 doi: 10.2319/112813-876.1. PMID: 24689849Free PMC Article

Clinical prediction guides

Lipofilling as refinement procedure in maxillo-mandibular malformations.
Cervelli D, Gasparini G, Moro A, Pelo S, Foresta E, Grussu F, D'Amato G, De Angelis P, Saponaro G
Acta Otorhinolaryngol Ital 2016 Oct;36(5):368-372. doi: 10.14639/0392-100X-857. PMID: 27958596Free PMC Article
Cephalometrics in Stickler syndrome: Objectification of the typical facial appearance.
Acke FR, Dhooge IJ, Malfait F, De Leenheer EM, De Pauw GA
J Craniomaxillofac Surg 2016 Jul;44(7):848-53. Epub 2016 Apr 15 doi: 10.1016/j.jcms.2016.04.010. PMID: 27193475
Periodontal condition and orofacial changes in patients with thalassemia major: a clinical and radiographic overview.
Hattab FN
J Clin Pediatr Dent 2012 Spring;36(3):301-7. PMID: 22838236
Class II correction improves nocturnal breathing in adolescents.
Schütz TC, Dominguez GC, Hallinan MP, Cunha TC, Tufik S
Angle Orthod 2011 Mar;81(2):222-8. doi: 10.2319/052710-233.1. PMID: 21208073Free PMC Article
Crouzonodermoskeletal syndrome.
Jeftha A, Stephen L, Morkel JA, Beighton P
J Clin Pediatr Dent 2004 Winter;28(2):173-6. doi: 10.17796/jcpd.28.2.72m01l5g50448548. PMID: 14969379

Recent systematic reviews

SH3BP2-related fibro-osseous disorders of the maxilla and mandible: A systematic review.
Kueper J, Tsimbal C, Olsen BR, Kaban L, Liao EC
Int J Oral Maxillofac Surg 2022 Jan;51(1):54-61. Epub 2021 Apr 30 doi: 10.1016/j.ijom.2021.04.001. PMID: 33941395
Is Counterclockwise Rotation of the Maxillomandibular Complex Stable Compared With Clockwise Rotation in the Correction of Dentofacial Deformities? A Systematic Review and Meta-Analysis.
Al-Moraissi EA, Wolford LM
J Oral Maxillofac Surg 2016 Oct;74(10):2066.e1-2066.e12. Epub 2016 Jun 11 doi: 10.1016/j.joms.2016.06.001. PMID: 27371873

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...