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Reduced contrast sensitivity

MedGen UID:
1671089
Concept ID:
C4732816
Finding
Synonym: Abnormal contrast sensitivity
 
HPO: HP:0032036

Definition

An abnormality in perception of contrast. Spatial contrast is a physical dimension referring to the light-dark transition of a border or an edge in an image that delineates the existence of a pattern or an object. Contrast sensitivity refers to a measure of how much contrast a person requires to see a target. Contrast-sensitivity measurements differ from acuity measurements; acuity is a measure of the spatial-resolving ability of the visual system under conditions of very high contrast, whereas contrast sensitivity is a measure of the threshold contrast for seeing a target. [from HPO]

Professional guidelines

PubMed

Heydarian S, Jafari R, Dailami KN, Hashemi H, Jafarzadehpour E, Heirani M, Yekta A, Mahjoob M, Khabazkhoob M
Int Ophthalmol 2020 Feb;40(2):511-527. Epub 2019 Oct 10 doi: 10.1007/s10792-019-01189-3. PMID: 31602527
Chang BC, Mirabella G, Yagev R, Banh M, Mezer E, Parkin PC, Westall CA, Buncic JR
Invest Ophthalmol Vis Sci 2007 Jun;48(6):2895-902. doi: 10.1167/iovs.06-0429. PMID: 17525226

Recent clinical studies

Therapy

Blanckaert E, Rouland JF, Davost T, Warniez A, Boucart M
Clin Exp Optom 2024 Mar;107(2):227-233. Epub 2022 Oct 2 doi: 10.1080/08164622.2022.2124848. PMID: 36183782
Perna J, Bellato A, Ganapathy PS, Solmi M, Zampieri A, Faraone SV, Cortese S
Mol Psychiatry 2023 Dec;28(12):5011-5023. Epub 2023 Jul 26 doi: 10.1038/s41380-023-02143-7. PMID: 37495888
Bickle KM, Mitchell GL, Walline JJ
Optom Vis Sci 2021 May 1;98(5):483-489. doi: 10.1097/OPX.0000000000001695. PMID: 33967252
McKee SP, Levi DM, Schor CM, Movshon JA
J Vis 2016;16(5):3. doi: 10.1167/16.5.3. PMID: 26943348Free PMC Article
Calladine D, Evans JR, Shah S, Leyland M
Cochrane Database Syst Rev 2012 Sep 12;(9):CD003169. doi: 10.1002/14651858.CD003169.pub3. PMID: 22972061

Prognosis

Liberski S, Confalonieri F, Cofta S, Petrovski G, Kocięcki J
Int J Mol Sci 2024 Jun 18;25(12) doi: 10.3390/ijms25126692. PMID: 38928397Free PMC Article
Okumura N, Padmanaban V, Balaji JJ, Srinivasan B, Hanada N, Komori Y, Yoshii K, Srinivas SP, Koizumi N, Padmanabhan P
Cornea 2022 Feb 1;41(2):171-176. doi: 10.1097/ICO.0000000000002814. PMID: 34369393
White UE, Black AA, Delbaere K, Wood JM
Ophthalmic Physiol Opt 2021 Mar;41(2):245-254. Epub 2020 Dec 25 doi: 10.1111/opo.12777. PMID: 33368495
Lipsky L, Qureshi HM, Friling R, Gaton DD, Rabina G, Dotan G
Eye (Lond) 2019 Jul;33(7):1068-1072. Epub 2019 Feb 19 doi: 10.1038/s41433-019-0361-y. PMID: 30783257Free PMC Article
Pepose JS
Am J Ophthalmol 2008 Nov;146(5):641-8. Epub 2008 Sep 13 doi: 10.1016/j.ajo.2008.07.033. PMID: 18789794

Clinical prediction guides

Perna J, Bellato A, Ganapathy PS, Solmi M, Zampieri A, Faraone SV, Cortese S
Mol Psychiatry 2023 Dec;28(12):5011-5023. Epub 2023 Jul 26 doi: 10.1038/s41380-023-02143-7. PMID: 37495888
Wang J, Cui Y, Vingopoulos F, Kasetty M, Silverman RF, Katz R, Kim L, Miller JB
Br J Ophthalmol 2022 Feb;106(2):241-245. Epub 2020 Nov 10 doi: 10.1136/bjophthalmol-2020-317615. PMID: 33172863
Wu D, Liu N, Xu P, Sun K, Xiao W, Li C
Perception 2020 Dec;49(12):1348-1361. Epub 2020 Nov 2 doi: 10.1177/0301006620967641. PMID: 33131398
Harper L, Spencer E, Davidson C, Hutchinson CV
Exp Brain Res 2020 Jan;238(1):51-62. Epub 2019 Nov 28 doi: 10.1007/s00221-019-05695-9. PMID: 31781821Free PMC Article
Kosovicheva A, Ferreira A, Vera-Diaz FA, Bex PJ
Vision Res 2019 Oct;163:52-62. Epub 2019 Aug 29 doi: 10.1016/j.visres.2019.08.004. PMID: 31404553Free PMC Article

Recent systematic reviews

Nguyen H, Di Tanna GL, Coxon K, Brown J, Ren K, Ramke J, Burton MJ, Gordon I, Zhang JH, Furtado J, Mdala S, Kitema GF, Keay L
BMJ Open 2023 Aug 11;13(8):e065210. doi: 10.1136/bmjopen-2022-065210. PMID: 37567751Free PMC Article
Perna J, Bellato A, Ganapathy PS, Solmi M, Zampieri A, Faraone SV, Cortese S
Mol Psychiatry 2023 Dec;28(12):5011-5023. Epub 2023 Jul 26 doi: 10.1038/s41380-023-02143-7. PMID: 37495888
White UE, Black AA, Delbaere K, Wood JM
Ophthalmic Physiol Opt 2021 Mar;41(2):245-254. Epub 2020 Dec 25 doi: 10.1111/opo.12777. PMID: 33368495
Wang SY, Stem MS, Oren G, Shtein R, Lichter PR
Eur J Ophthalmol 2017 Jun 26;27(4):387-401. Epub 2017 Apr 24 doi: 10.5301/ejo.5000978. PMID: 28574135
Calladine D, Evans JR, Shah S, Leyland M
Cochrane Database Syst Rev 2012 Sep 12;(9):CD003169. doi: 10.1002/14651858.CD003169.pub3. PMID: 22972061

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