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Recurrent Hepatocellular Carcinoma

MedGen UID:
167832
Concept ID:
C0861876
Neoplastic Process
Synonyms: Hepatocellular Carcinoma, Recurrent; Recurrent Carcinoma of Liver Cell; Recurrent Carcinoma of the Liver Cell; Recurrent Hepatoma; Recurrent Liver Cell Carcinoma; Relapsed Carcinoma of Liver Cell; Relapsed Carcinoma of the Liver Cell; Relapsed Hepatocellular Carcinoma; Relapsed Hepatoma; Relapsed Liver Cell Carcinoma

Definition

The reemergence of hepatocellular carcinoma after a period of remission [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Hepatocellular Carcinoma

Professional guidelines

PubMed

Famularo S, Donadon M, Cipriani F, Fazio F, Ardito F, Iaria M, Perri P, Conci S, Dominioni T, Lai Q, La Barba G, Patauner S, Molfino S, Germani P, Zimmitti G, Pinotti E, Zanello M, Fumagalli L, Ferrari C, Romano M, Delvecchio A, Valsecchi MG, Antonucci A, Piscaglia F, Farinati F, Kawaguchi Y, Hasegawa K, Memeo R, Zanus G, Griseri G, Chiarelli M, Jovine E, Zago M, Abu Hilal M, Tarchi P, Baiocchi GL, Frena A, Ercolani G, Rossi M, Maestri M, Ruzzenente A, Grazi GL, Dalla Valle R, Romano F, Giuliante F, Ferrero A, Aldrighetti L, Bernasconi DP, Torzilli G; HE.RC.O.LE.S. Group
JAMA Surg 2023 Feb 1;158(2):192-202. doi: 10.1001/jamasurg.2022.6697. PMID: 36576813Free PMC Article
Gupta S, Khan S, Kawka M, Gujjuri R, Chau I, Starling N, Cunningham D, Jiao LR, Gall T
Expert Rev Gastroenterol Hepatol 2021 Oct;15(10):1159-1167. Epub 2021 Aug 18 doi: 10.1080/17474124.2021.1967144. PMID: 34402366
Expert Panel on Gastrointestinal Imaging:, Horowitz JM, Kamel IR, Arif-Tiwari H, Asrani SK, Hindman NM, Kaur H, McNamara MM, Noto RB, Qayyum A, Lalani T
J Am Coll Radiol 2017 May;14(5S):S103-S117. doi: 10.1016/j.jacr.2017.02.011. PMID: 28473066

Recent clinical studies

Etiology

Bang K, Casadei-Gardini A, Yoo C, Iavarone M, Ryu MH, Park SR, Kim HD, Yoon YI, Jung DH, Park GC, Ahn CS, Moon DB, Hwang S, Kim KH, Song GW, Mazzarelli C, Alimenti E, Chan SL, De Giorgio M, Ryoo BY, Lee SG
Cancer Med 2023 Feb;12(3):2572-2579. Epub 2022 Aug 5 doi: 10.1002/cam4.5123. PMID: 36812124Free PMC Article
Famularo S, Donadon M, Cipriani F, Fazio F, Ardito F, Iaria M, Perri P, Conci S, Dominioni T, Lai Q, La Barba G, Patauner S, Molfino S, Germani P, Zimmitti G, Pinotti E, Zanello M, Fumagalli L, Ferrari C, Romano M, Delvecchio A, Valsecchi MG, Antonucci A, Piscaglia F, Farinati F, Kawaguchi Y, Hasegawa K, Memeo R, Zanus G, Griseri G, Chiarelli M, Jovine E, Zago M, Abu Hilal M, Tarchi P, Baiocchi GL, Frena A, Ercolani G, Rossi M, Maestri M, Ruzzenente A, Grazi GL, Dalla Valle R, Romano F, Giuliante F, Ferrero A, Aldrighetti L, Bernasconi DP, Torzilli G; HE.RC.O.LE.S. Group
JAMA Surg 2023 Feb 1;158(2):192-202. doi: 10.1001/jamasurg.2022.6697. PMID: 36576813Free PMC Article
Yoh T, Seo S, Taura K, Iguchi K, Ogiso S, Fukumitsu K, Ishii T, Kaido T, Uemoto S
Ann Surg 2021 Apr 1;273(4):792-799. doi: 10.1097/SLA.0000000000003358. PMID: 31058698
Xia Y, Li J, Liu G, Wang K, Qian G, Lu Z, Yang T, Yan Z, Lei Z, Si A, Wan X, Zhang H, Gao C, Cheng Z, Pawlik TM, Wang H, Lau WY, Wu M, Shen F
JAMA Oncol 2020 Feb 1;6(2):255-263. doi: 10.1001/jamaoncol.2019.4477. PMID: 31774468Free PMC Article
Gavriilidis P, Askari A, Azoulay D
HPB (Oxford) 2017 Jan;19(1):3-9. Epub 2016 Oct 27 doi: 10.1016/j.hpb.2016.10.003. PMID: 28341429

Diagnosis

Buros C, Dave AA, Furlan A
Radiol Clin North Am 2023 Sep;61(5):785-795. Epub 2023 May 16 doi: 10.1016/j.rcl.2023.04.002. PMID: 37495287
Bhatt A, Wu J
World J Gastroenterol 2023 Apr 21;29(15):2261-2271. doi: 10.3748/wjg.v29.i15.2261. PMID: 37124885Free PMC Article
Yoh T, Seo S, Taura K, Iguchi K, Ogiso S, Fukumitsu K, Ishii T, Kaido T, Uemoto S
Ann Surg 2021 Apr 1;273(4):792-799. doi: 10.1097/SLA.0000000000003358. PMID: 31058698
Lee MW, Lim HK
World J Gastroenterol 2018 Dec 14;24(46):5215-5222. doi: 10.3748/wjg.v24.i46.5215. PMID: 30581270Free PMC Article
Expert Panel on Gastrointestinal Imaging:, Horowitz JM, Kamel IR, Arif-Tiwari H, Asrani SK, Hindman NM, Kaur H, McNamara MM, Noto RB, Qayyum A, Lalani T
J Am Coll Radiol 2017 May;14(5S):S103-S117. doi: 10.1016/j.jacr.2017.02.011. PMID: 28473066

Therapy

Buros C, Dave AA, Furlan A
Radiol Clin North Am 2023 Sep;61(5):785-795. Epub 2023 May 16 doi: 10.1016/j.rcl.2023.04.002. PMID: 37495287
Famularo S, Donadon M, Cipriani F, Fazio F, Ardito F, Iaria M, Perri P, Conci S, Dominioni T, Lai Q, La Barba G, Patauner S, Molfino S, Germani P, Zimmitti G, Pinotti E, Zanello M, Fumagalli L, Ferrari C, Romano M, Delvecchio A, Valsecchi MG, Antonucci A, Piscaglia F, Farinati F, Kawaguchi Y, Hasegawa K, Memeo R, Zanus G, Griseri G, Chiarelli M, Jovine E, Zago M, Abu Hilal M, Tarchi P, Baiocchi GL, Frena A, Ercolani G, Rossi M, Maestri M, Ruzzenente A, Grazi GL, Dalla Valle R, Romano F, Giuliante F, Ferrero A, Aldrighetti L, Bernasconi DP, Torzilli G; HE.RC.O.LE.S. Group
JAMA Surg 2023 Feb 1;158(2):192-202. doi: 10.1001/jamasurg.2022.6697. PMID: 36576813Free PMC Article
Kim TH, Koh YH, Kim BH, Kim MJ, Lee JH, Park B, Park JW
J Hepatol 2021 Mar;74(3):603-612. Epub 2020 Oct 5 doi: 10.1016/j.jhep.2020.09.026. PMID: 33031846
Lee MW, Lim HK
World J Gastroenterol 2018 Dec 14;24(46):5215-5222. doi: 10.3748/wjg.v24.i46.5215. PMID: 30581270Free PMC Article
Kim BH, Park JW
J Korean Med Sci 2018 Nov 5;33(45):e286. Epub 2018 Oct 16 doi: 10.3346/jkms.2018.33.e286. PMID: 30402051Free PMC Article

Prognosis

Famularo S, Donadon M, Cipriani F, Fazio F, Ardito F, Iaria M, Perri P, Conci S, Dominioni T, Lai Q, La Barba G, Patauner S, Molfino S, Germani P, Zimmitti G, Pinotti E, Zanello M, Fumagalli L, Ferrari C, Romano M, Delvecchio A, Valsecchi MG, Antonucci A, Piscaglia F, Farinati F, Kawaguchi Y, Hasegawa K, Memeo R, Zanus G, Griseri G, Chiarelli M, Jovine E, Zago M, Abu Hilal M, Tarchi P, Baiocchi GL, Frena A, Ercolani G, Rossi M, Maestri M, Ruzzenente A, Grazi GL, Dalla Valle R, Romano F, Giuliante F, Ferrero A, Aldrighetti L, Bernasconi DP, Torzilli G; HE.RC.O.LE.S. Group
JAMA Surg 2023 Feb 1;158(2):192-202. doi: 10.1001/jamasurg.2022.6697. PMID: 36576813Free PMC Article
Yoh T, Seo S, Taura K, Iguchi K, Ogiso S, Fukumitsu K, Ishii T, Kaido T, Uemoto S
Ann Surg 2021 Apr 1;273(4):792-799. doi: 10.1097/SLA.0000000000003358. PMID: 31058698
Häfner SJ
Biomed J 2019 Oct;42(5):293-298. Epub 2019 Nov 7 doi: 10.1016/j.bj.2019.10.001. PMID: 31783989Free PMC Article
de'Angelis N, Landi F, Carra MC, Azoulay D
World J Gastroenterol 2015 Oct 21;21(39):11185-98. doi: 10.3748/wjg.v21.i39.11185. PMID: 26494973Free PMC Article
Thomasset SC, Dennison AR, Garcea G
World J Surg 2015 May;39(5):1150-60. doi: 10.1007/s00268-015-2956-1. PMID: 25634340

Clinical prediction guides

Famularo S, Donadon M, Cipriani F, Fazio F, Ardito F, Iaria M, Perri P, Conci S, Dominioni T, Lai Q, La Barba G, Patauner S, Molfino S, Germani P, Zimmitti G, Pinotti E, Zanello M, Fumagalli L, Ferrari C, Romano M, Delvecchio A, Valsecchi MG, Antonucci A, Piscaglia F, Farinati F, Kawaguchi Y, Hasegawa K, Memeo R, Zanus G, Griseri G, Chiarelli M, Jovine E, Zago M, Abu Hilal M, Tarchi P, Baiocchi GL, Frena A, Ercolani G, Rossi M, Maestri M, Ruzzenente A, Grazi GL, Dalla Valle R, Romano F, Giuliante F, Ferrero A, Aldrighetti L, Bernasconi DP, Torzilli G; HE.RC.O.LE.S. Group
JAMA Surg 2023 Feb 1;158(2):192-202. doi: 10.1001/jamasurg.2022.6697. PMID: 36576813Free PMC Article
Kim TH, Koh YH, Kim BH, Kim MJ, Lee JH, Park B, Park JW
J Hepatol 2021 Mar;74(3):603-612. Epub 2020 Oct 5 doi: 10.1016/j.jhep.2020.09.026. PMID: 33031846
Xia Y, Li J, Liu G, Wang K, Qian G, Lu Z, Yang T, Yan Z, Lei Z, Si A, Wan X, Zhang H, Gao C, Cheng Z, Pawlik TM, Wang H, Lau WY, Wu M, Shen F
JAMA Oncol 2020 Feb 1;6(2):255-263. doi: 10.1001/jamaoncol.2019.4477. PMID: 31774468Free PMC Article
Häfner SJ
Biomed J 2019 Oct;42(5):293-298. Epub 2019 Nov 7 doi: 10.1016/j.bj.2019.10.001. PMID: 31783989Free PMC Article
Welker MW, Bechstein WO, Zeuzem S, Trojan J
Transpl Int 2013 Feb;26(2):109-18. Epub 2012 Sep 21 doi: 10.1111/j.1432-2277.2012.01562.x. PMID: 22994652

Recent systematic reviews

Macdonald DB, Walsh CB, McInnes MDF
J Magn Reson Imaging 2020 Oct;52(4):1029-1030. Epub 2019 Nov 6 doi: 10.1002/jmri.26989. PMID: 31696591
Gavriilidis P, Askari A, Azoulay D
HPB (Oxford) 2017 Jan;19(1):3-9. Epub 2016 Oct 27 doi: 10.1016/j.hpb.2016.10.003. PMID: 28341429
de'Angelis N, Landi F, Carra MC, Azoulay D
World J Gastroenterol 2015 Oct 21;21(39):11185-98. doi: 10.3748/wjg.v21.i39.11185. PMID: 26494973Free PMC Article
Thomasset SC, Dennison AR, Garcea G
World J Surg 2015 May;39(5):1150-60. doi: 10.1007/s00268-015-2956-1. PMID: 25634340
Rubin J, Ayoub N, Kaldas F, Saab S
Exp Clin Transplant 2012 Dec;10(6):531-43. doi: 10.6002/ect.2012.0085. PMID: 23216564

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