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Recurrent Anaplastic Pleomorphic Xanthoastrocytoma

MedGen UID:
1685266
•Concept ID:
C5205645
•
Neoplastic Process

Definition

The reemergence of anaplastic pleomorphic xanthoastrocytoma after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Anaplastic Pleomorphic Xanthoastrocytoma

Professional guidelines

PubMed

Clinical importance of eflornithine (α-difluoromethylornithine) for the treatment of malignant gliomas.
Levin VA, Ictech SE, Hess KR
CNS Oncol 2018 Apr;7(2):CNS16. Epub 2018 Jan 30 doi: 10.2217/cns-2017-0031. PMID: 29378419Free PMC Article
The genetic basis of intradural spinal tumors and its impact on clinical treatment.
Karsy M, Guan J, Sivakumar W, Neil JA, Schmidt MH, Mahan MA
Neurosurg Focus 2015 Aug;39(2):E3. doi: 10.3171/2015.5.FOCUS15143. PMID: 26235020
Treatment updates regarding anaplastic oligodendroglioma and anaplastic oligoastrocytoma.
Khan KA, Abbasi AN, Ali N
J Coll Physicians Surg Pak 2014 Dec;24(12):935-9. PMID: 25523732

Recent clinical studies

Therapy

Challenges and Perspectives of Standard Therapy and Drug Development in High-Grade Gliomas.
Chelliah SS, Paul EAL, Kamarudin MNA, Parhar I
Molecules 2021 Feb 22;26(4) doi: 10.3390/molecules26041169. PMID: 33671796Free PMC Article
Evidence-Based Practice: Temozolomide Beyond Glioblastoma.
Chua J, Nafziger E, Leung D
Curr Oncol Rep 2019 Mar 5;21(4):30. doi: 10.1007/s11912-019-0783-5. PMID: 30835007
Chemotherapy in glioma.
Taal W, Bromberg JE, van den Bent MJ
CNS Oncol 2015;4(3):179-92. Epub 2015 Apr 23 doi: 10.2217/cns.15.2. PMID: 25906059Free PMC Article
Treatment updates regarding anaplastic oligodendroglioma and anaplastic oligoastrocytoma.
Khan KA, Abbasi AN, Ali N
J Coll Physicians Surg Pak 2014 Dec;24(12):935-9. PMID: 25523732
Malignant gliomas.
Burton EC, Prados MD
Curr Treat Options Oncol 2000 Dec;1(5):459-68. doi: 10.1007/s11864-000-0073-2. PMID: 12057153

Prognosis

Spinal Pleomorphic Xanthoastrocytoma: Case Report and Literature Review.
Tan D, Lai LT, Daly CD, Tran V, Maingard J, Timms C
World Neurosurg 2020 Sep;141:25-32. Epub 2020 May 19 doi: 10.1016/j.wneu.2020.05.117. PMID: 32442731
Evidence-Based Practice: Temozolomide Beyond Glioblastoma.
Chua J, Nafziger E, Leung D
Curr Oncol Rep 2019 Mar 5;21(4):30. doi: 10.1007/s11912-019-0783-5. PMID: 30835007
Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations.
Reinhardt A, Stichel D, Schrimpf D, Sahm F, Korshunov A, Reuss DE, Koelsche C, Huang K, Wefers AK, Hovestadt V, Sill M, Gramatzki D, Felsberg J, Reifenberger G, Koch A, Thomale UW, Becker A, Hans VH, Prinz M, Staszewski O, Acker T, Dohmen H, Hartmann C, Mueller W, Tuffaha MSA, Paulus W, Heß K, Brokinkel B, Schittenhelm J, Monoranu CM, Kessler AF, Loehr M, Buslei R, Deckert M, Mawrin C, Kohlhof P, Hewer E, Olar A, Rodriguez FJ, Giannini C, NageswaraRao AA, Tabori U, Nunes NM, Weller M, Pohl U, Jaunmuktane Z, Brandner S, Unterberg A, Hänggi D, Platten M, Pfister SM, Wick W, Herold-Mende C, Jones DTW, von Deimling A, Capper D
Acta Neuropathol 2018 Aug;136(2):273-291. Epub 2018 Mar 21 doi: 10.1007/s00401-018-1837-8. PMID: 29564591
Treatment updates regarding anaplastic oligodendroglioma and anaplastic oligoastrocytoma.
Khan KA, Abbasi AN, Ali N
J Coll Physicians Surg Pak 2014 Dec;24(12):935-9. PMID: 25523732
Malignant gliomas.
Burton EC, Prados MD
Curr Treat Options Oncol 2000 Dec;1(5):459-68. doi: 10.1007/s11864-000-0073-2. PMID: 12057153

Clinical prediction guides

Biology and grading of pleomorphic xanthoastrocytoma-what have we learned about it?
Vaubel R, Zschernack V, Tran QT, Jenkins S, Caron A, Milosevic D, Smadbeck J, Vasmatzis G, Kandels D, Gnekow A, Kramm C, Jenkins R, Kipp BR, Rodriguez FJ, Orr BA, Pietsch T, Giannini C
Brain Pathol 2021 Jan;31(1):20-32. Epub 2020 Aug 4 doi: 10.1111/bpa.12874. PMID: 32619305Free PMC Article
Evidence-Based Practice: Temozolomide Beyond Glioblastoma.
Chua J, Nafziger E, Leung D
Curr Oncol Rep 2019 Mar 5;21(4):30. doi: 10.1007/s11912-019-0783-5. PMID: 30835007
5-Aminolevulinic acid fluorescence guided surgery for recurrent high-grade gliomas.
Chohan MO, Berger MS
J Neurooncol 2019 Feb;141(3):517-522. Epub 2018 Aug 10 doi: 10.1007/s11060-018-2956-8. PMID: 30097823
Temozolomide for recurrent high-grade glioma.
Macdonald DR
Semin Oncol 2001 Aug;28(4 Suppl 13):3-12. doi: 10.1016/s0093-7754(01)90065-x. PMID: 11550133
Anaplastic pleomorphic xanthoastrocytoma.
Bayindir C, Balak N, Karasu A, Kasaroğlu D
Childs Nerv Syst 1997 Jan;13(1):50-6. doi: 10.1007/s003810050040. PMID: 9083703

Recent systematic reviews

Cerebellar pleomorphic xanthoastrocytoma in the setting of neurofibromatosis type-I: Does it portend a different prognosis? A case report and systematic review.
Mathkour M, Banerjee S, Werner C, Hanna J, Abou-Al-Shaar H, Dindial R, Scullen T, Boehm L, Tubbs RS, Ware ML
Clin Neurol Neurosurg 2021 Jan;200:106346. Epub 2020 Nov 2 doi: 10.1016/j.clineuro.2020.106346. PMID: 33160715
A rapid and systematic review of the effectiveness of temozolomide for the treatment of recurrent malignant glioma.
Dinnes J, Cave C, Huang S, Milne R
Br J Cancer 2002 Feb 12;86(4):501-5. doi: 10.1038/sj.bjc.6600135. PMID: 11870527Free PMC Article
Treatment of recurrent high grade astrocytoma; results of a systematic review of 1,415 patients.
Huncharek M, Muscat J
Anticancer Res 1998 Mar-Apr;18(2B):1303-11. PMID: 9615807

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