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Retinal nerve fiber edema

MedGen UID:
1689646
Concept ID:
C5209223
Pathologic Function
Synonym: Retinal nerve fibre oedema
 
HPO: HP:0020120

Definition

Swelling (edema) of the retinal nerve fibers. [from HPO]

Term Hierarchy

Conditions with this feature

Leber hereditary optic neuropathy, autosomal recessive
MedGen UID:
1786310
Concept ID:
C5543589
Disease or Syndrome

Professional guidelines

PubMed

Wichrowska M, Goździewska E, Kocięcki J
Front Biosci (Landmark Ed) 2023 Sep 25;28(9):222. doi: 10.31083/j.fbl2809222. PMID: 37796711
Sibony PA, Kupersmith MJ, Kardon RH
J Neuroophthalmol 2021 Mar 1;41(1):77-92. doi: 10.1097/WNO.0000000000001078. PMID: 32909979Free PMC Article
Oshitari T, Mitamura Y
Curr Diabetes Rev 2010 Jul;6(4):207-14. doi: 10.2174/157339910791658862. PMID: 20522019

Recent clinical studies

Etiology

Nislic E, Trnacevic S, Pidro A, Djozic A, Begic E
Transplant Proc 2022 Oct;54(8):2192-2196. Epub 2022 Sep 13 doi: 10.1016/j.transproceed.2022.08.001. PMID: 36109201
Oertel FC, Sotirchos ES, Zimmermann HG, Motamedi S, Specovius S, Asseyer ES, Chien C, Cook L, Vasileiou E, Filippatou A, Calabresi PA, Saidha S, Pandit L, D'Cunha A, Outteryck O, Zéphir H, Pittock S, Flanagan EP, Bhatti MT, Rommer PS, Bsteh G, Zrzavy T, Kuempfel T, Aktas O, Ringelstein M, Albrecht P, Ayzenberg I, Pakeerathan T, Knier B, Aly L, Asgari N, Soelberg K, Marignier R, Tilikete CF, Cobo Calvo A, Villoslada P, Sanchez-Dalmau B, Martinez-Lapiscina EH, Llufriu S, Green AJ, Yeaman MR, Smith TJ, Brandt AU, Chen J, Paul F, Havla J; with the GJCF International Clinical Consortium for NMOSD and the CROCTINO study group
Ann Neurol 2022 Sep;92(3):476-485. Epub 2022 Jul 16 doi: 10.1002/ana.26440. PMID: 35703428
Au A, Hilely A, Scharf J, Gunnemann F, Wang D, Chehaibou I, Iovino C, Grondin C, Farecki ML, Falavarjani KG, Phasukkijwatana N, Battista M, Borrelli E, Sacconi R, Powell B, Hom G, Greenlee TE, Conti TF, Ledesma-Gil G, Teke MY, Choudhry N, Fung AT, Krivosic V, Baek J, Lee MY, Sugiura Y, Querques G, Peiretti E, Rosen R, Lee WK, Yannuzzi LA, Zur D, Loewenstein A, Pauleikhoff D, Singh R, Modi Y, Hubschman JP, Ip M, Sadda S, Freund KB, Sarraf D
Invest Ophthalmol Vis Sci 2020 May 11;61(5):54. doi: 10.1167/iovs.61.5.54. PMID: 32460316Free PMC Article
Lim HB, Sung JY, Ahn SI, Jo YJ, Kim JY
Optom Vis Sci 2018 Mar;95(3):247-255. doi: 10.1097/OPX.0000000000001181. PMID: 29420438
Wilczyński M, Kucharczyk M, Filatow S
Klin Oczna 2014;116(3):180-3. PMID: 25799781

Diagnosis

Sibony PA, Kupersmith MJ, Kardon RH
J Neuroophthalmol 2021 Mar 1;41(1):77-92. doi: 10.1097/WNO.0000000000001078. PMID: 32909979Free PMC Article
Suciu CI, Suciu VI, Nicoara SD
J Diabetes Res 2020;2020:6655021. Epub 2020 Dec 31 doi: 10.1155/2020/6655021. PMID: 33490283Free PMC Article
Pierro L, Rabiolo A
Dev Ophthalmol 2017;60:28-37. Epub 2017 Apr 20 doi: 10.1159/000459723. PMID: 28427062
Midena E, Pilotto E
Dev Ophthalmol 2017;60:16-27. Epub 2017 Apr 20 doi: 10.1159/000459687. PMID: 28427061
Ripandelli G, Coppé AM, Capaldo A, Stirpe M
Semin Ophthalmol 1998 Dec;13(4):199-202. doi: 10.3109/08820539809056053. PMID: 9878670

Therapy

Zeki Fikret C, Simsek E, Ucgun NI, Kulahcioglu E
Photodiagnosis Photodyn Ther 2023 Dec;44:103880. Epub 2023 Nov 4 doi: 10.1016/j.pdpdt.2023.103880. PMID: 37931695
Nislic E, Trnacevic S, Pidro A, Djozic A, Begic E
Transplant Proc 2022 Oct;54(8):2192-2196. Epub 2022 Sep 13 doi: 10.1016/j.transproceed.2022.08.001. PMID: 36109201
Lee AG, Mader TH, Gibson CR, Brunstetter TJ, Tarver WJ
Eye (Lond) 2018 Jul;32(7):1164-1167. Epub 2018 Mar 12 doi: 10.1038/s41433-018-0070-y. PMID: 29527011Free PMC Article
Barber AJ, Baccouche B
Vision Res 2017 Oct;139:82-92. Epub 2017 Oct 16 doi: 10.1016/j.visres.2017.06.014. PMID: 28988945
Lee AG, Mader TH, Gibson CR, Tarver W
JAMA Ophthalmol 2017 Sep 1;135(9):992-994. doi: 10.1001/jamaophthalmol.2017.2396. PMID: 28727859

Prognosis

Sibony PA, Kupersmith MJ, Kardon RH
J Neuroophthalmol 2021 Mar 1;41(1):77-92. doi: 10.1097/WNO.0000000000001078. PMID: 32909979Free PMC Article
Suciu CI, Suciu VI, Nicoara SD
J Diabetes Res 2020;2020:6655021. Epub 2020 Dec 31 doi: 10.1155/2020/6655021. PMID: 33490283Free PMC Article
Au A, Hilely A, Scharf J, Gunnemann F, Wang D, Chehaibou I, Iovino C, Grondin C, Farecki ML, Falavarjani KG, Phasukkijwatana N, Battista M, Borrelli E, Sacconi R, Powell B, Hom G, Greenlee TE, Conti TF, Ledesma-Gil G, Teke MY, Choudhry N, Fung AT, Krivosic V, Baek J, Lee MY, Sugiura Y, Querques G, Peiretti E, Rosen R, Lee WK, Yannuzzi LA, Zur D, Loewenstein A, Pauleikhoff D, Singh R, Modi Y, Hubschman JP, Ip M, Sadda S, Freund KB, Sarraf D
Invest Ophthalmol Vis Sci 2020 May 11;61(5):54. doi: 10.1167/iovs.61.5.54. PMID: 32460316Free PMC Article
Stefánsson E, Olafsdottir OB, Eliasdottir TS, Vehmeijer W, Einarsdottir AB, Bek T, Torp TL, Grauslund J, Eysteinsson T, Karlsson RA, Van Keer K, Stalmans I, Vandewalle E, Todorova MG, Hammer M, Garhöfer G, Schmetterer L, Šín M, Hardarson SH
Prog Retin Eye Res 2019 May;70:1-22. Epub 2019 Apr 15 doi: 10.1016/j.preteyeres.2019.04.001. PMID: 30999027
Onal S, Tugal-Tutkun I, Neri P, P Herbort C
Int Ophthalmol 2014 Apr;34(2):401-35. Epub 2013 Jul 9 doi: 10.1007/s10792-013-9822-7. PMID: 23835664

Clinical prediction guides

Stefánsson E, Olafsdottir OB, Eliasdottir TS, Vehmeijer W, Einarsdottir AB, Bek T, Torp TL, Grauslund J, Eysteinsson T, Karlsson RA, Van Keer K, Stalmans I, Vandewalle E, Todorova MG, Hammer M, Garhöfer G, Schmetterer L, Šín M, Hardarson SH
Prog Retin Eye Res 2019 May;70:1-22. Epub 2019 Apr 15 doi: 10.1016/j.preteyeres.2019.04.001. PMID: 30999027
Lim HB, Sung JY, Ahn SI, Jo YJ, Kim JY
Optom Vis Sci 2018 Mar;95(3):247-255. doi: 10.1097/OPX.0000000000001181. PMID: 29420438
Barber AJ, Baccouche B
Vision Res 2017 Oct;139:82-92. Epub 2017 Oct 16 doi: 10.1016/j.visres.2017.06.014. PMID: 28988945
Kardon R
J Neuroophthalmol 2014 Sep;34 Suppl:S10-7. doi: 10.1097/WNO.0000000000000162. PMID: 25133965
Onal S, Tugal-Tutkun I, Neri P, P Herbort C
Int Ophthalmol 2014 Apr;34(2):401-35. Epub 2013 Jul 9 doi: 10.1007/s10792-013-9822-7. PMID: 23835664

Recent systematic reviews

Nita M, Grzybowski A
Curr Pharm Des 2017;23(4):639-654. doi: 10.2174/1381612823666170111095723. PMID: 28078992

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