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Unresectable Pancreatic Adenocarcinoma

MedGen UID:
1690009
Concept ID:
C5206250
Neoplastic Process

Definition

Pancreatic adenocarcinoma that is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Pancreatic Adenocarcinoma

Professional guidelines

PubMed

Shahrouki P, Lee EW
Pancreas 2021 Oct 1;50(9):e79-e80. doi: 10.1097/MPA.0000000000001915. PMID: 34860823
Hall WA, Goodman KA
Radiat Oncol 2019 Jun 26;14(1):114. doi: 10.1186/s13014-019-1277-1. PMID: 31242912Free PMC Article
Toesca DAS, Koong AJ, Poultsides GA, Visser BC, Haraldsdottir S, Koong AC, Chang DT
Int J Radiat Oncol Biol Phys 2018 Apr 1;100(5):1155-1174. doi: 10.1016/j.ijrobp.2017.12.287. PMID: 29722658

Recent clinical studies

Etiology

Sakakida T, Ishikawa T, Doi T, Morita R, Kataoka S, Miyake H, Yamaguchi K, Moriguchi M, Sogame Y, Yasuda H, Iwasaku M, Konishi H, Takayama K, Itoh Y
J Gastroenterol 2024 Feb;59(2):145-156. Epub 2023 Nov 25 doi: 10.1007/s00535-023-02058-8. PMID: 38006445
Jang JK, Byun JH, Kang JH, Son JH, Kim JH, Lee SS, Kim HJ, Yoo C, Kim KP, Hong SM, Seo DW, Kim SC, Lee MG
Eur Radiol 2021 Feb;31(2):813-823. Epub 2020 Aug 26 doi: 10.1007/s00330-020-07188-8. PMID: 32845389
Tavakkoli A, Elmunzer BJ, Waljee AK, Murphy CC, Pruitt SL, Zhu H, Rong R, Kwon RS, Scheiman JM, Rubenstein JH, Singal AG
Gastrointest Endosc 2021 Jan;93(1):154-162.e5. Epub 2020 Jun 9 doi: 10.1016/j.gie.2020.05.061. PMID: 32531402Free PMC Article
Stackhouse KA, Storino A, Watkins AA, Gooding W, Callery MP, Kent TS, Sawhney MS, Moser AJ
HPB (Oxford) 2020 Apr;22(4):563-569. Epub 2019 Sep 17 doi: 10.1016/j.hpb.2019.08.014. PMID: 31537457
Toesca DAS, Koong AJ, Poultsides GA, Visser BC, Haraldsdottir S, Koong AC, Chang DT
Int J Radiat Oncol Biol Phys 2018 Apr 1;100(5):1155-1174. doi: 10.1016/j.ijrobp.2017.12.287. PMID: 29722658

Diagnosis

Redegalli M, Grassini G, Magliacane G, Pecciarini L, Schiavo Lena M, Smart CE, Johnston RL, Waddell N, Maestro R, Macchini M, Orsi G, Petrone MC, Rossi G, Balzano G, Falconi M, Arcidiacono PG, Reni M, Doglioni C, Cangi MG
Clin Gastroenterol Hepatol 2023 Oct;21(11):2825-2833. Epub 2022 Oct 22 doi: 10.1016/j.cgh.2022.10.014. PMID: 36280101
Hill CS, Rosati L, Wang H, Tsai HL, He J, Hacker-Prietz A, Laheru DA, Zheng L, Sehgal S, Bernard V, Le DT, Pawlik TM, Weiss MJ, Narang AK, Herman JM
Pract Radiat Oncol 2022 Nov-Dec;12(6):511-523. Epub 2022 Mar 17 doi: 10.1016/j.prro.2022.02.009. PMID: 35306231Free PMC Article
Jang JK, Byun JH, Kang JH, Son JH, Kim JH, Lee SS, Kim HJ, Yoo C, Kim KP, Hong SM, Seo DW, Kim SC, Lee MG
Eur Radiol 2021 Feb;31(2):813-823. Epub 2020 Aug 26 doi: 10.1007/s00330-020-07188-8. PMID: 32845389
Tavakkoli A, Elmunzer BJ, Waljee AK, Murphy CC, Pruitt SL, Zhu H, Rong R, Kwon RS, Scheiman JM, Rubenstein JH, Singal AG
Gastrointest Endosc 2021 Jan;93(1):154-162.e5. Epub 2020 Jun 9 doi: 10.1016/j.gie.2020.05.061. PMID: 32531402Free PMC Article
Toesca DAS, Ahmed F, Kashyap M, Baclay JRM, von Eyben R, Pollom EL, Koong AC, Chang DT
Radiother Oncol 2020 Nov;152:63-69. Epub 2020 Aug 5 doi: 10.1016/j.radonc.2020.07.053. PMID: 32763253

Therapy

Jang JK, Byun JH, Kang JH, Son JH, Kim JH, Lee SS, Kim HJ, Yoo C, Kim KP, Hong SM, Seo DW, Kim SC, Lee MG
Eur Radiol 2021 Feb;31(2):813-823. Epub 2020 Aug 26 doi: 10.1007/s00330-020-07188-8. PMID: 32845389
Hall WA, Goodman KA
Radiat Oncol 2019 Jun 26;14(1):114. doi: 10.1186/s13014-019-1277-1. PMID: 31242912Free PMC Article
Toesca DAS, Koong AJ, Poultsides GA, Visser BC, Haraldsdottir S, Koong AC, Chang DT
Int J Radiat Oncol Biol Phys 2018 Apr 1;100(5):1155-1174. doi: 10.1016/j.ijrobp.2017.12.287. PMID: 29722658
Assifi MM, Lu X, Eibl G, Reber HA, Li G, Hines OJ
Surgery 2011 Sep;150(3):466-73. doi: 10.1016/j.surg.2011.07.006. PMID: 21878232Free PMC Article
Jessup JM, Steele G Jr, Mayer RJ, Posner M, Busse P, Cady B, Stone M, Jenkins R, Osteen R
Arch Surg 1993 May;128(5):559-64. doi: 10.1001/archsurg.1993.01420170093014. PMID: 8098206

Prognosis

Redegalli M, Grassini G, Magliacane G, Pecciarini L, Schiavo Lena M, Smart CE, Johnston RL, Waddell N, Maestro R, Macchini M, Orsi G, Petrone MC, Rossi G, Balzano G, Falconi M, Arcidiacono PG, Reni M, Doglioni C, Cangi MG
Clin Gastroenterol Hepatol 2023 Oct;21(11):2825-2833. Epub 2022 Oct 22 doi: 10.1016/j.cgh.2022.10.014. PMID: 36280101
Jang JK, Byun JH, Kang JH, Son JH, Kim JH, Lee SS, Kim HJ, Yoo C, Kim KP, Hong SM, Seo DW, Kim SC, Lee MG
Eur Radiol 2021 Feb;31(2):813-823. Epub 2020 Aug 26 doi: 10.1007/s00330-020-07188-8. PMID: 32845389
Stackhouse KA, Storino A, Watkins AA, Gooding W, Callery MP, Kent TS, Sawhney MS, Moser AJ
HPB (Oxford) 2020 Apr;22(4):563-569. Epub 2019 Sep 17 doi: 10.1016/j.hpb.2019.08.014. PMID: 31537457
Toesca DAS, Koong AJ, Poultsides GA, Visser BC, Haraldsdottir S, Koong AC, Chang DT
Int J Radiat Oncol Biol Phys 2018 Apr 1;100(5):1155-1174. doi: 10.1016/j.ijrobp.2017.12.287. PMID: 29722658
Assifi MM, Lu X, Eibl G, Reber HA, Li G, Hines OJ
Surgery 2011 Sep;150(3):466-73. doi: 10.1016/j.surg.2011.07.006. PMID: 21878232Free PMC Article

Clinical prediction guides

Redegalli M, Grassini G, Magliacane G, Pecciarini L, Schiavo Lena M, Smart CE, Johnston RL, Waddell N, Maestro R, Macchini M, Orsi G, Petrone MC, Rossi G, Balzano G, Falconi M, Arcidiacono PG, Reni M, Doglioni C, Cangi MG
Clin Gastroenterol Hepatol 2023 Oct;21(11):2825-2833. Epub 2022 Oct 22 doi: 10.1016/j.cgh.2022.10.014. PMID: 36280101
Jang JK, Byun JH, Kang JH, Son JH, Kim JH, Lee SS, Kim HJ, Yoo C, Kim KP, Hong SM, Seo DW, Kim SC, Lee MG
Eur Radiol 2021 Feb;31(2):813-823. Epub 2020 Aug 26 doi: 10.1007/s00330-020-07188-8. PMID: 32845389
Winther SB, Bjerregaard JK, Schonnemann KR, Ejlsmark MW, Krogh M, Jensen HA, Pfeiffer P
Cancer Chemother Pharmacol 2018 Mar;81(3):573-578. Epub 2018 Jan 31 doi: 10.1007/s00280-018-3528-5. PMID: 29387963
Ogawa K, Ito Y, Hirokawa N, Shibuya K, Kokubo M, Ogo E, Shibuya H, Saito T, Onishi H, Karasawa K, Nemoto K, Nishimura Y; Japanese Radiation Oncology Study Group Working Subgroup of Gastrointestinal Cancers
Int J Radiat Oncol Biol Phys 2012 Jun 1;83(2):559-65. Epub 2011 Oct 20 doi: 10.1016/j.ijrobp.2011.07.013. PMID: 22019243
Assifi MM, Lu X, Eibl G, Reber HA, Li G, Hines OJ
Surgery 2011 Sep;150(3):466-73. doi: 10.1016/j.surg.2011.07.006. PMID: 21878232Free PMC Article

Supplemental Content

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    Practice guidelines

    • PubMed
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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

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