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Unresectable Lung Neuroendocrine Neoplasm

MedGen UID:
1711232
Concept ID:
C5237195
Neoplastic Process

Definition

A lung neuroendocrine neoplasm that is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Lung Neuroendocrine Neoplasm

Professional guidelines

PubMed

Prinzi N, Rossi RE, Proto C, Leuzzi G, Raimondi A, Torchio M, Milione M, Corti F, Colombo E, Prisciandaro M, Cascella T, Spreafico C, Beninato T, Coppa J, Lo Russo G, Di Bartolomeo M, de Braud F, Pusceddu S
Clin Lung Cancer 2021 May;22(3):161-169. Epub 2020 Dec 17 doi: 10.1016/j.cllc.2020.12.004. PMID: 33618994
Wolin EM
Chest 2017 May;151(5):1141-1146. Epub 2016 Jun 29 doi: 10.1016/j.chest.2016.06.018. PMID: 27373769
Caplin ME, Baudin E, Ferolla P, Filosso P, Garcia-Yuste M, Lim E, Oberg K, Pelosi G, Perren A, Rossi RE, Travis WD; ENETS consensus conference participants
Ann Oncol 2015 Aug;26(8):1604-20. Epub 2015 Feb 2 doi: 10.1093/annonc/mdv041. PMID: 25646366

Recent clinical studies

Etiology

Morizane C, Machida N, Honma Y, Okusaka T, Boku N, Kato K, Nomura S, Hiraoka N, Sekine S, Taniguchi H, Okano N, Yamaguchi K, Sato T, Ikeda M, Mizuno N, Ozaka M, Kataoka T, Ueno M, Kitagawa Y, Terashima M, Furuse J; Japan Clinical Oncology Group (JCOG)
JAMA Oncol 2022 Oct 1;8(10):1447-1455. doi: 10.1001/jamaoncol.2022.3395. PMID: 35980649Free PMC Article
Marabelle A, Fakih M, Lopez J, Shah M, Shapira-Frommer R, Nakagawa K, Chung HC, Kindler HL, Lopez-Martin JA, Miller WH Jr, Italiano A, Kao S, Piha-Paul SA, Delord JP, McWilliams RR, Fabrizio DA, Aurora-Garg D, Xu L, Jin F, Norwood K, Bang YJ
Lancet Oncol 2020 Oct;21(10):1353-1365. Epub 2020 Sep 10 doi: 10.1016/S1470-2045(20)30445-9. PMID: 32919526
Hasskarl J
Recent Results Cancer Res 2018;211:101-123. doi: 10.1007/978-3-319-91442-8_8. PMID: 30069763
Hendifar AE, Marchevsky AM, Tuli R
J Thorac Oncol 2017 Mar;12(3):425-436. Epub 2016 Nov 24 doi: 10.1016/j.jtho.2016.11.2222. PMID: 27890494
Wolin EM
Chest 2017 May;151(5):1141-1146. Epub 2016 Jun 29 doi: 10.1016/j.chest.2016.06.018. PMID: 27373769

Diagnosis

Prinzi N, Rossi RE, Proto C, Leuzzi G, Raimondi A, Torchio M, Milione M, Corti F, Colombo E, Prisciandaro M, Cascella T, Spreafico C, Beninato T, Coppa J, Lo Russo G, Di Bartolomeo M, de Braud F, Pusceddu S
Clin Lung Cancer 2021 May;22(3):161-169. Epub 2020 Dec 17 doi: 10.1016/j.cllc.2020.12.004. PMID: 33618994
Hendifar AE, Marchevsky AM, Tuli R
J Thorac Oncol 2017 Mar;12(3):425-436. Epub 2016 Nov 24 doi: 10.1016/j.jtho.2016.11.2222. PMID: 27890494
Wolin EM
Chest 2017 May;151(5):1141-1146. Epub 2016 Jun 29 doi: 10.1016/j.chest.2016.06.018. PMID: 27373769
Caplin ME, Baudin E, Ferolla P, Filosso P, Garcia-Yuste M, Lim E, Oberg K, Pelosi G, Perren A, Rossi RE, Travis WD; ENETS consensus conference participants
Ann Oncol 2015 Aug;26(8):1604-20. Epub 2015 Feb 2 doi: 10.1093/annonc/mdv041. PMID: 25646366
Tekautz TM, Pratt CB, Jenkins JJ, Spunt SL
J Pediatr Surg 2003 Sep;38(9):1317-21. doi: 10.1016/s0022-3468(03)00388-9. PMID: 14523812

Therapy

Morizane C, Machida N, Honma Y, Okusaka T, Boku N, Kato K, Nomura S, Hiraoka N, Sekine S, Taniguchi H, Okano N, Yamaguchi K, Sato T, Ikeda M, Mizuno N, Ozaka M, Kataoka T, Ueno M, Kitagawa Y, Terashima M, Furuse J; Japan Clinical Oncology Group (JCOG)
JAMA Oncol 2022 Oct 1;8(10):1447-1455. doi: 10.1001/jamaoncol.2022.3395. PMID: 35980649Free PMC Article
Marabelle A, Fakih M, Lopez J, Shah M, Shapira-Frommer R, Nakagawa K, Chung HC, Kindler HL, Lopez-Martin JA, Miller WH Jr, Italiano A, Kao S, Piha-Paul SA, Delord JP, McWilliams RR, Fabrizio DA, Aurora-Garg D, Xu L, Jin F, Norwood K, Bang YJ
Lancet Oncol 2020 Oct;21(10):1353-1365. Epub 2020 Sep 10 doi: 10.1016/S1470-2045(20)30445-9. PMID: 32919526
Buchbinder EI, Desai A
Am J Clin Oncol 2016 Feb;39(1):98-106. doi: 10.1097/COC.0000000000000239. PMID: 26558876Free PMC Article
Caplin ME, Baudin E, Ferolla P, Filosso P, Garcia-Yuste M, Lim E, Oberg K, Pelosi G, Perren A, Rossi RE, Travis WD; ENETS consensus conference participants
Ann Oncol 2015 Aug;26(8):1604-20. Epub 2015 Feb 2 doi: 10.1093/annonc/mdv041. PMID: 25646366
Garbe C, Abusaif S, Eigentler TK
Recent Results Cancer Res 2014;201:215-25. doi: 10.1007/978-3-642-54490-3_13. PMID: 24756795

Prognosis

Sun TY, Hendifar A, Padda SK
Curr Oncol Rep 2022 Jul;24(7):819-824. Epub 2022 Mar 19 doi: 10.1007/s11912-022-01253-9. PMID: 35305210
Prinzi N, Rossi RE, Proto C, Leuzzi G, Raimondi A, Torchio M, Milione M, Corti F, Colombo E, Prisciandaro M, Cascella T, Spreafico C, Beninato T, Coppa J, Lo Russo G, Di Bartolomeo M, de Braud F, Pusceddu S
Clin Lung Cancer 2021 May;22(3):161-169. Epub 2020 Dec 17 doi: 10.1016/j.cllc.2020.12.004. PMID: 33618994
Marabelle A, Fakih M, Lopez J, Shah M, Shapira-Frommer R, Nakagawa K, Chung HC, Kindler HL, Lopez-Martin JA, Miller WH Jr, Italiano A, Kao S, Piha-Paul SA, Delord JP, McWilliams RR, Fabrizio DA, Aurora-Garg D, Xu L, Jin F, Norwood K, Bang YJ
Lancet Oncol 2020 Oct;21(10):1353-1365. Epub 2020 Sep 10 doi: 10.1016/S1470-2045(20)30445-9. PMID: 32919526
Hendifar AE, Marchevsky AM, Tuli R
J Thorac Oncol 2017 Mar;12(3):425-436. Epub 2016 Nov 24 doi: 10.1016/j.jtho.2016.11.2222. PMID: 27890494
Caplin ME, Baudin E, Ferolla P, Filosso P, Garcia-Yuste M, Lim E, Oberg K, Pelosi G, Perren A, Rossi RE, Travis WD; ENETS consensus conference participants
Ann Oncol 2015 Aug;26(8):1604-20. Epub 2015 Feb 2 doi: 10.1093/annonc/mdv041. PMID: 25646366

Clinical prediction guides

Malandrino P, Feola T, Mikovic N, Cannavale G, Molfetta SD, Altieri B, Mancini C, Ferolla P, Colao A, Faggiano A; NIKE Group
Semin Nucl Med 2024 Jul;54(4):570-580. Epub 2024 May 28 doi: 10.1053/j.semnuclmed.2024.05.001. PMID: 38811266
Ferolla P, Berruti A, Spada F, Brizzi MP, Ibrahim T, Marconcini R, Giuffrida D, Amoroso V, La Salvia A, Vaccaro V, Faggiano A, Colao A, Volante M, Ghizzoni S, Mazzanti P, Houchard A, Fazio N
Neuroendocrinology 2023;113(3):332-342. Epub 2022 Aug 31 doi: 10.1159/000526811. PMID: 36044870
Chan DL, Rodriguez-Freixinos V, Doherty M, Wasson K, Iscoe N, Raskin W, Hallet J, Myrehaug S, Law C, Thawer A, Nguyen K, Singh S
Eur J Cancer 2022 Jul;169:74-81. Epub 2022 May 2 doi: 10.1016/j.ejca.2022.03.029. PMID: 35504244
Sun TY, Hendifar A, Padda SK
Curr Oncol Rep 2022 Jul;24(7):819-824. Epub 2022 Mar 19 doi: 10.1007/s11912-022-01253-9. PMID: 35305210
Marabelle A, Fakih M, Lopez J, Shah M, Shapira-Frommer R, Nakagawa K, Chung HC, Kindler HL, Lopez-Martin JA, Miller WH Jr, Italiano A, Kao S, Piha-Paul SA, Delord JP, McWilliams RR, Fabrizio DA, Aurora-Garg D, Xu L, Jin F, Norwood K, Bang YJ
Lancet Oncol 2020 Oct;21(10):1353-1365. Epub 2020 Sep 10 doi: 10.1016/S1470-2045(20)30445-9. PMID: 32919526

Recent systematic reviews

Malandrino P, Feola T, Mikovic N, Cannavale G, Molfetta SD, Altieri B, Mancini C, Ferolla P, Colao A, Faggiano A; NIKE Group
Semin Nucl Med 2024 Jul;54(4):570-580. Epub 2024 May 28 doi: 10.1053/j.semnuclmed.2024.05.001. PMID: 38811266
Egeler MD, van Leeuwen M, Fraterman I, van den Heuvel NMJ, Boekhout AH, Lai-Kwon J, Wilthagen EA, Eriksson H, Haanen JB, Wilgenhof S, Ascierto PA, van Akkooi ACJ, van de Poll-Franse LV
Crit Rev Oncol Hematol 2023 Mar;183:103919. Epub 2023 Feb 1 doi: 10.1016/j.critrevonc.2023.103919. PMID: 36736511
Mujica-Mota R, Varley-Campbell J, Tikhonova I, Cooper C, Griffin E, Haasova M, Peters J, Lucherini S, Talens-Bou J, Long L, Sherriff D, Napier M, Ramage J, Hoyle M
Health Technol Assess 2018 Sep;22(49):1-326. doi: 10.3310/hta22490. PMID: 30209002Free PMC Article
Caplin ME, Baudin E, Ferolla P, Filosso P, Garcia-Yuste M, Lim E, Oberg K, Pelosi G, Perren A, Rossi RE, Travis WD; ENETS consensus conference participants
Ann Oncol 2015 Aug;26(8):1604-20. Epub 2015 Feb 2 doi: 10.1093/annonc/mdv041. PMID: 25646366
Rosen AC, Wu S, Damse A, Sherman E, Lacouture ME
J Clin Endocrinol Metab 2012 Apr;97(4):1125-33. Epub 2012 Feb 29 doi: 10.1210/jc.2011-2677. PMID: 22378813

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