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Non-convulsive status epilepticus with coma

MedGen UID:
1718567
•Concept ID:
C5397676
•
Disease or Syndrome
Synonym: Subtle status epilepticus
 
HPO: HP:0032659

Definition

A type of status epilepticus without prominent motor symptoms and in the presence of coma. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNon-convulsive status epilepticus with coma

Professional guidelines

PubMed

Management of status epilepticus: a narrative review.
Migdady I, Rosenthal ES, Cock HR
Anaesthesia 2022 Jan;77 Suppl 1:78-91. doi: 10.1111/anae.15606. PMID: 35001380
Guidelines for the diagnosis and treatment of acute encephalopathy in childhood.
Mizuguchi M, Ichiyama T, Imataka G, Okumura A, Goto T, Sakuma H, Takanashi JI, Murayama K, Yamagata T, Yamanouchi H, Fukuda T, Maegaki Y
Brain Dev 2021 Jan;43(1):2-31. Epub 2020 Aug 20 doi: 10.1016/j.braindev.2020.08.001. PMID: 32829972
Treatment of Refractory and Super-refractory Status Epilepticus.
Rai S, Drislane FW
Neurotherapeutics 2018 Jul;15(3):697-712. doi: 10.1007/s13311-018-0640-5. PMID: 29922905Free PMC Article

Recent clinical studies

Etiology

Seizures, Status Epilepticus, and Continuous EEG in the Intensive Care Unit.
Rosenthal ES
Continuum (Minneap Minn) 2021 Oct 1;27(5):1321-1343. doi: 10.1212/CON.0000000000001012. PMID: 34618762
Non convulsive status epilepticus in the elderly.
Dupont S
Geriatr Psychol Neuropsychiatr Vieil 2019 Mar 1;17(S1):25-30. doi: 10.1684/pnv.2019.0782. PMID: 30916648
Treatment of Refractory and Super-refractory Status Epilepticus.
Rai S, Drislane FW
Neurotherapeutics 2018 Jul;15(3):697-712. doi: 10.1007/s13311-018-0640-5. PMID: 29922905Free PMC Article
Cefepime-induced neurotoxicity: a systematic review.
Payne LE, Gagnon DJ, Riker RR, Seder DB, Glisic EK, Morris JG, Fraser GL
Crit Care 2017 Nov 14;21(1):276. doi: 10.1186/s13054-017-1856-1. PMID: 29137682Free PMC Article
Optimizing sedation in patients with acute brain injury.
Oddo M, Crippa IA, Mehta S, Menon D, Payen JF, Taccone FS, Citerio G
Crit Care 2016 May 5;20(1):128. doi: 10.1186/s13054-016-1294-5. PMID: 27145814Free PMC Article

Diagnosis

Management of status epilepticus: a narrative review.
Migdady I, Rosenthal ES, Cock HR
Anaesthesia 2022 Jan;77 Suppl 1:78-91. doi: 10.1111/anae.15606. PMID: 35001380
Guidelines for the diagnosis and treatment of acute encephalopathy in childhood.
Mizuguchi M, Ichiyama T, Imataka G, Okumura A, Goto T, Sakuma H, Takanashi JI, Murayama K, Yamagata T, Yamanouchi H, Fukuda T, Maegaki Y
Brain Dev 2021 Jan;43(1):2-31. Epub 2020 Aug 20 doi: 10.1016/j.braindev.2020.08.001. PMID: 32829972
Non convulsive status epilepticus in the elderly.
Dupont S
Geriatr Psychol Neuropsychiatr Vieil 2019 Mar 1;17(S1):25-30. doi: 10.1684/pnv.2019.0782. PMID: 30916648
Treatment of Refractory and Super-refractory Status Epilepticus.
Rai S, Drislane FW
Neurotherapeutics 2018 Jul;15(3):697-712. doi: 10.1007/s13311-018-0640-5. PMID: 29922905Free PMC Article
Cefepime-induced neurotoxicity: a systematic review.
Payne LE, Gagnon DJ, Riker RR, Seder DB, Glisic EK, Morris JG, Fraser GL
Crit Care 2017 Nov 14;21(1):276. doi: 10.1186/s13054-017-1856-1. PMID: 29137682Free PMC Article

Therapy

Management of status epilepticus: a narrative review.
Migdady I, Rosenthal ES, Cock HR
Anaesthesia 2022 Jan;77 Suppl 1:78-91. doi: 10.1111/anae.15606. PMID: 35001380
Seizures, Status Epilepticus, and Continuous EEG in the Intensive Care Unit.
Rosenthal ES
Continuum (Minneap Minn) 2021 Oct 1;27(5):1321-1343. doi: 10.1212/CON.0000000000001012. PMID: 34618762
Non convulsive status epilepticus in the elderly.
Dupont S
Geriatr Psychol Neuropsychiatr Vieil 2019 Mar 1;17(S1):25-30. doi: 10.1684/pnv.2019.0782. PMID: 30916648
Cefepime-induced neurotoxicity: a systematic review.
Payne LE, Gagnon DJ, Riker RR, Seder DB, Glisic EK, Morris JG, Fraser GL
Crit Care 2017 Nov 14;21(1):276. doi: 10.1186/s13054-017-1856-1. PMID: 29137682Free PMC Article
Optimizing sedation in patients with acute brain injury.
Oddo M, Crippa IA, Mehta S, Menon D, Payen JF, Taccone FS, Citerio G
Crit Care 2016 May 5;20(1):128. doi: 10.1186/s13054-016-1294-5. PMID: 27145814Free PMC Article

Prognosis

Management of status epilepticus: a narrative review.
Migdady I, Rosenthal ES, Cock HR
Anaesthesia 2022 Jan;77 Suppl 1:78-91. doi: 10.1111/anae.15606. PMID: 35001380
Guidelines for the diagnosis and treatment of acute encephalopathy in childhood.
Mizuguchi M, Ichiyama T, Imataka G, Okumura A, Goto T, Sakuma H, Takanashi JI, Murayama K, Yamagata T, Yamanouchi H, Fukuda T, Maegaki Y
Brain Dev 2021 Jan;43(1):2-31. Epub 2020 Aug 20 doi: 10.1016/j.braindev.2020.08.001. PMID: 32829972
Non convulsive status epilepticus in the elderly.
Dupont S
Geriatr Psychol Neuropsychiatr Vieil 2019 Mar 1;17(S1):25-30. doi: 10.1684/pnv.2019.0782. PMID: 30916648
Cefepime-induced neurotoxicity: a systematic review.
Payne LE, Gagnon DJ, Riker RR, Seder DB, Glisic EK, Morris JG, Fraser GL
Crit Care 2017 Nov 14;21(1):276. doi: 10.1186/s13054-017-1856-1. PMID: 29137682Free PMC Article
Diagnosis of reversible causes of coma.
Edlow JA, Rabinstein A, Traub SJ, Wijdicks EF
Lancet 2014 Dec 6;384(9959):2064-76. Epub 2014 Apr 21 doi: 10.1016/S0140-6736(13)62184-4. PMID: 24767707

Clinical prediction guides

Outcomes in Patients With COVID-19 With Acute Encephalopathy and Coma: An International Prospective Study.
Legriel S, Badenes R, Engrand N, Mendoza-Trujillo R, Soulier P, Benghanem S, Pizzi M, Maciel C, Chelly J, Zuber B, Labruyere M, Plantefeve G, Jacq G, Galbois A, Launey Y, Argaud L, Lesieur O, Ferre A, Paul M, Guillon A, Bailly P, Beuret P, de-Carne MC, Siami S, Benzekri D, Colin G, Gaviria L, Aldana JL, Bruel C, Stoclin A, Sedillot N, Geri G, Samano D, Sobczak E, Swafford E, O'Phelan K, Meffert A, Holleville M, Silva S, Alves da Costa MJ, Mejia J, Alkhachroum A; for NeuroCovid19
Neurology 2023 May 30;100(22):e2247-e2258. Epub 2023 Apr 11 doi: 10.1212/WNL.0000000000207263. PMID: 37041081Free PMC Article
Comparing Patients With Isolated Seizures and Status Epilepticus in Intensive Care Units: An Observational Cohort Study.
Wagner AS, Baumann SM, Semmlack S, Frei AI, Rüegg S, Hunziker S, Marsch S, Sutter R
Neurology 2023 Apr 25;100(17):e1763-e1775. Epub 2023 Mar 6 doi: 10.1212/WNL.0000000000206838. PMID: 36878696Free PMC Article
Risk Factors and Prognosis of Early Posttraumatic Seizures in Moderate to Severe Traumatic Brain Injury.
Laing J, Gabbe B, Chen Z, Perucca P, Kwan P, O'Brien TJ
JAMA Neurol 2022 Apr 1;79(4):334-341. doi: 10.1001/jamaneurol.2021.5420. PMID: 35188950Free PMC Article
Seizures, Status Epilepticus, and Continuous EEG in the Intensive Care Unit.
Rosenthal ES
Continuum (Minneap Minn) 2021 Oct 1;27(5):1321-1343. doi: 10.1212/CON.0000000000001012. PMID: 34618762
Non traumatic coma.
Bansal A, Singhi SC, Singhi PD, Khandelwal N, Ramesh S
Indian J Pediatr 2005 Jun;72(6):467-73. doi: 10.1007/BF02724422. PMID: 15985734

Recent systematic reviews

EEG Patterns and Outcomes After Hypoxic Brain Injury: A Systematic Review and Meta-analysis.
Perera K, Khan S, Singh S, Kromm J, Wang M, Sajobi T, Jetté N, Wiebe S, Josephson CB
Neurocrit Care 2022 Feb;36(1):292-301. Epub 2021 Aug 11 doi: 10.1007/s12028-021-01322-0. PMID: 34379270
Cefepime-induced neurotoxicity: a systematic review.
Payne LE, Gagnon DJ, Riker RR, Seder DB, Glisic EK, Morris JG, Fraser GL
Crit Care 2017 Nov 14;21(1):276. doi: 10.1186/s13054-017-1856-1. PMID: 29137682Free PMC Article
Propofol versus thiopental sodium for the treatment of refractory status epilepticus.
Prabhakar H, Kalaivani M
Cochrane Database Syst Rev 2017 Feb 3;2(2):CD009202. doi: 10.1002/14651858.CD009202.pub4. PMID: 28155226Free PMC Article
Propofol versus thiopental sodium for the treatment of refractory status epilepticus.
Prabhakar H, Kalaivani M
Cochrane Database Syst Rev 2015 Jun 25;(6):CD009202. doi: 10.1002/14651858.CD009202.pub3. PMID: 26111021
Predicting neurologic outcome after targeted temperature management for cardiac arrest: systematic review and meta-analysis.
Golan E, Barrett K, Alali AS, Duggal A, Jichici D, Pinto R, Morrison L, Scales DC
Crit Care Med 2014 Aug;42(8):1919-30. doi: 10.1097/CCM.0000000000000335. PMID: 24717465

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