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Pulmonary hypertensive crisis

MedGen UID:
1720698
•Concept ID:
C2363966
•
Disease or Syndrome
Synonym: Pulmonary arterial hypertension crisis
 
HPO: HP:0033352

Definition

Pulmonary hypertensive crisis involves sudden and potentially lethal increases in PAP and PVR that cause acute rise in right atrial and right ventricular end-diastolic pressure accompanied by low cardiac output. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPulmonary hypertensive crisis

Professional guidelines

PubMed

Perioperative management of patients with pulmonary hypertension undergoing non-cardiothoracic, non-obstetric surgery: a systematic review and expert consensus statement.
Price LC, Martinez G, Brame A, Pickworth T, Samaranayake C, Alexander D, Garfield B, Aw TC, McCabe C, Mukherjee B, Harries C, Kempny A, Gatzoulis M, Marino P, Kiely DG, Condliffe R, Howard L, Davies R, Coghlan G, Schreiber BE, Lordan J, Taboada D, Gaine S, Johnson M, Church C, Kemp SV, Wong D, Curry A, Levett D, Price S, Ledot S, Reed A, Dimopoulos K, Wort SJ
Br J Anaesth 2021 Apr;126(4):774-790. Epub 2021 Feb 19 doi: 10.1016/j.bja.2021.01.005. PMID: 33612249
Emergency Management of Pediatric Pulmonary Hypertension.
Del Pizzo J, Hanna B
Pediatr Emerg Care 2016 Jan;32(1):49-55. doi: 10.1097/PEC.0000000000000674. PMID: 26720067
The anesthetic management of children with pulmonary hypertension in the cardiac catheterization laboratory.
Twite MD, Friesen RH
Anesthesiol Clin 2014 Mar;32(1):157-73. Epub 2013 Dec 17 doi: 10.1016/j.anclin.2013.10.005. PMID: 24491655

Recent clinical studies

Etiology

Perioperative management of patients with pulmonary hypertension undergoing non-cardiothoracic, non-obstetric surgery: a systematic review and expert consensus statement.
Price LC, Martinez G, Brame A, Pickworth T, Samaranayake C, Alexander D, Garfield B, Aw TC, McCabe C, Mukherjee B, Harries C, Kempny A, Gatzoulis M, Marino P, Kiely DG, Condliffe R, Howard L, Davies R, Coghlan G, Schreiber BE, Lordan J, Taboada D, Gaine S, Johnson M, Church C, Kemp SV, Wong D, Curry A, Levett D, Price S, Ledot S, Reed A, Dimopoulos K, Wort SJ
Br J Anaesth 2021 Apr;126(4):774-790. Epub 2021 Feb 19 doi: 10.1016/j.bja.2021.01.005. PMID: 33612249
Pulmonary Hypertensive Crisis on Induction of Anesthesia.
Schisler T, Marquez JM, Hilmi I, Subramaniam K
Semin Cardiothorac Vasc Anesth 2017 Mar;21(1):105-113. Epub 2016 Aug 1 doi: 10.1177/1089253216652222. PMID: 27252226
Clinical characteristics of pulmonary arterial hypertension associated with Down syndrome.
Saji T
Pediatr Int 2014 Jun;56(3):297-303. doi: 10.1111/ped.12349. PMID: 24689825
The anesthetic management of children with pulmonary hypertension in the cardiac catheterization laboratory.
Twite MD, Friesen RH
Anesthesiol Clin 2014 Mar;32(1):157-73. Epub 2013 Dec 17 doi: 10.1016/j.anclin.2013.10.005. PMID: 24491655
Anesthetic management of children with pulmonary arterial hypertension.
Friesen RH, Williams GD
Paediatr Anaesth 2008 Mar;18(3):208-16. doi: 10.1111/j.1460-9592.2008.02419.x. PMID: 18230063

Diagnosis

Perioperative management of patients with pulmonary hypertension undergoing non-cardiothoracic, non-obstetric surgery: a systematic review and expert consensus statement.
Price LC, Martinez G, Brame A, Pickworth T, Samaranayake C, Alexander D, Garfield B, Aw TC, McCabe C, Mukherjee B, Harries C, Kempny A, Gatzoulis M, Marino P, Kiely DG, Condliffe R, Howard L, Davies R, Coghlan G, Schreiber BE, Lordan J, Taboada D, Gaine S, Johnson M, Church C, Kemp SV, Wong D, Curry A, Levett D, Price S, Ledot S, Reed A, Dimopoulos K, Wort SJ
Br J Anaesth 2021 Apr;126(4):774-790. Epub 2021 Feb 19 doi: 10.1016/j.bja.2021.01.005. PMID: 33612249
Emergency Management of Pediatric Pulmonary Hypertension.
Del Pizzo J, Hanna B
Pediatr Emerg Care 2016 Jan;32(1):49-55. doi: 10.1097/PEC.0000000000000674. PMID: 26720067
The anesthetic management of children with pulmonary hypertension in the cardiac catheterization laboratory.
Twite MD, Friesen RH
Anesthesiol Clin 2014 Mar;32(1):157-73. Epub 2013 Dec 17 doi: 10.1016/j.anclin.2013.10.005. PMID: 24491655
Obstructive total anomalous pulmonary venous drainage.
Nabar A, Dalvi B
Indian J Pediatr 1998 Jan-Feb;65(1):35-45. doi: 10.1007/BF02849692. PMID: 10771945
Diagnosis and management of postoperative pulmonary hypertensive crisis.
Wheller J, George BL, Mulder DG, Jarmakani JM
Circulation 1979 Dec;60(7):1640-4. doi: 10.1161/01.cir.60.7.1640. PMID: 498483

Therapy

Thiamine-responsive, life-threatening, pulmonary hypertensive crisis with encephalopathy in young infants: A case series.
C S, Kundana PK, Reddy N, Reddy B S, Poddutoor P, Rizwan A, Konanki R
Eur J Paediatr Neurol 2022 Jan;36:93-98. Epub 2021 Dec 17 doi: 10.1016/j.ejpn.2021.12.010. PMID: 34952263
Nitroglycerin inhalation for acute treatment of pulmonary arterial hypertension in children with congenital heart disease.
Marwali EM, Rayhan M, Roebiono PS
Cardiol Young 2021 Sep;31(9):1381-1385. Epub 2021 Jun 4 doi: 10.1017/S1047951121002092. PMID: 34082850
Pulmonary hypertensive crisis and its efficient management. A Case report and literature review.
Khan KK, Khan FH
J Pak Med Assoc 2017 Jun;67(6):936-938. PMID: 28585598
Pulmonary Hypertensive Crisis on Induction of Anesthesia.
Schisler T, Marquez JM, Hilmi I, Subramaniam K
Semin Cardiothorac Vasc Anesth 2017 Mar;21(1):105-113. Epub 2016 Aug 1 doi: 10.1177/1089253216652222. PMID: 27252226
Anesthetic management of children with pulmonary arterial hypertension.
Friesen RH, Williams GD
Paediatr Anaesth 2008 Mar;18(3):208-16. doi: 10.1111/j.1460-9592.2008.02419.x. PMID: 18230063

Prognosis

The CRASH report: emergency management dilemmas facing acute physicians in patients with pulmonary arterial hypertension.
Price LC, Dimopoulos K, Marino P, Alonso-Gonzalez R, McCabe C, Kemnpy A, Swan L, Boutsikou M, Al Zahrani A, Coghlan GJ, Schreiber BE, Howard LS, Davies R, Toshner M, Pepke-Zaba J, Church AC, Peacock A, Corris PA, Lordan JL, Gaine S, Condliffe R, Kiely DG, Wort SJ
Thorax 2017 Nov;72(11):1035-1045. Epub 2017 Sep 12 doi: 10.1136/thoraxjnl-2016-209725. PMID: 28904006
Pulmonary Hypertensive Crisis on Induction of Anesthesia.
Schisler T, Marquez JM, Hilmi I, Subramaniam K
Semin Cardiothorac Vasc Anesth 2017 Mar;21(1):105-113. Epub 2016 Aug 1 doi: 10.1177/1089253216652222. PMID: 27252226
Peri-operative pulmonary hypertension in paediatric patients: current strategies in children with congenital heart disease.
Gorenflo M, Gu H, Xu Z
Cardiology 2010;116(1):10-7. Epub 2010 Apr 24 doi: 10.1159/000313864. PMID: 20424447
Anesthetic management of children with pulmonary arterial hypertension.
Friesen RH, Williams GD
Paediatr Anaesth 2008 Mar;18(3):208-16. doi: 10.1111/j.1460-9592.2008.02419.x. PMID: 18230063
Obstructive total anomalous pulmonary venous drainage.
Nabar A, Dalvi B
Indian J Pediatr 1998 Jan-Feb;65(1):35-45. doi: 10.1007/BF02849692. PMID: 10771945

Clinical prediction guides

Evaluation of maternal-fetal outcomes in pregnancy complicated with severe pulmonary hypertension and its influencing factors: a single-center retrospective study in China.
Dai Q, Shang M, Zhou Y, Wei Q
J Matern Fetal Neonatal Med 2023 Dec;36(2):2290923. Epub 2023 Dec 6 doi: 10.1080/14767058.2023.2290923. PMID: 38057124
Pregnancy outcomes of women with Eisenmenger syndrome: A single-center study.
Liu Y, Li Y, Zhang J, Zhao Y, Liu K, Li J, Zhao M, Gu H, Fan X, Wang J
Int J Cardiol 2023 Mar 1;374:35-41. Epub 2022 Dec 13 doi: 10.1016/j.ijcard.2022.12.014. PMID: 36526021
Low cardiac output thyroid storm in a girl with Graves' disease.
Chantra M, Limsuwan A, Mahachoklertwattana P
Pediatr Int 2016 Oct;58(10):1080-1083. doi: 10.1111/ped.13102. PMID: 27804243
Inflammation and congenital heart disease associated pulmonary hypertension.
Gursoy M, Salihoglu E, Hatemi AC, Hokenek AF, Ozkan S, Ceyran H
Heart Surg Forum 2015 Feb 27;18(1):E38-41. doi: 10.1532/hsf.1228. PMID: 25881225
Peri-operative pulmonary hypertension in paediatric patients: current strategies in children with congenital heart disease.
Gorenflo M, Gu H, Xu Z
Cardiology 2010;116(1):10-7. Epub 2010 Apr 24 doi: 10.1159/000313864. PMID: 20424447

Recent systematic reviews

Perioperative management of patients with pulmonary hypertension undergoing non-cardiothoracic, non-obstetric surgery: a systematic review and expert consensus statement.
Price LC, Martinez G, Brame A, Pickworth T, Samaranayake C, Alexander D, Garfield B, Aw TC, McCabe C, Mukherjee B, Harries C, Kempny A, Gatzoulis M, Marino P, Kiely DG, Condliffe R, Howard L, Davies R, Coghlan G, Schreiber BE, Lordan J, Taboada D, Gaine S, Johnson M, Church C, Kemp SV, Wong D, Curry A, Levett D, Price S, Ledot S, Reed A, Dimopoulos K, Wort SJ
Br J Anaesth 2021 Apr;126(4):774-790. Epub 2021 Feb 19 doi: 10.1016/j.bja.2021.01.005. PMID: 33612249
Safety and effect of sildenafil on treating paediatric pulmonary arterial hypertension: a meta-analysis on the randomised controlled trials.
Zhang Q, Xu B, Lv J, Wang Z, Du J
Cardiol Young 2020 Dec;30(12):1882-1889. Epub 2020 Oct 20 doi: 10.1017/S104795112000311X. PMID: 33077013

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