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Gallbladder Adenoma, Intestinal-Type

MedGen UID:
1762235
•Concept ID:
C5419818
•
Neoplastic Process

Definition

An adenoma that arises from the gallbladder and is associated with intestinal-type differentiation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGallbladder Adenoma, Intestinal-Type

Recent clinical studies

Etiology

Cystadenomas of the liver and extrahepatic bile ducts: Morphologic and immunohistochemical characterization of the biliary and intestinal variants.
Albores-Saavedra J, Córdova-Ramón JC, Chablé-Montero F, Dorantes-Heredia R, Henson DE
Ann Diagn Pathol 2015 Jun;19(3):124-9. Epub 2015 Mar 6 doi: 10.1016/j.anndiagpath.2015.03.001. PMID: 25792461

Diagnosis

Pathogenesis of carcinoma of the papilla of Vater.
Fischer HP, Zhou H
J Hepatobiliary Pancreat Surg 2004;11(5):301-9. doi: 10.1007/s00534-004-0898-3. PMID: 15549428
The homeobox intestinal differentiation factor CDX2 is selectively expressed in gastrointestinal adenocarcinomas.
Kaimaktchiev V, Terracciano L, Tornillo L, Spichtin H, Stoios D, Bundi M, Korcheva V, Mirlacher M, Loda M, Sauter G, Corless CL
Mod Pathol 2004 Nov;17(11):1392-9. doi: 10.1038/modpathol.3800205. PMID: 15205684
p53 and Ki-67 immunoreactivity and nuclear morphometry of 'carcinoma-in-adenoma' and adenoma of the gall-bladder.
Takei K, Watanabe H, Itoi T, Saito T
Pathol Int 1996 Nov;46(11):908-17. doi: 10.1111/j.1440-1827.1996.tb03569.x. PMID: 8970203

Prognosis

Cystadenomas of the liver and extrahepatic bile ducts: Morphologic and immunohistochemical characterization of the biliary and intestinal variants.
Albores-Saavedra J, Córdova-Ramón JC, Chablé-Montero F, Dorantes-Heredia R, Henson DE
Ann Diagn Pathol 2015 Jun;19(3):124-9. Epub 2015 Mar 6 doi: 10.1016/j.anndiagpath.2015.03.001. PMID: 25792461
Histopathologic features and frequency of gall bladder lesions in consecutive 540 cholecystectomies.
Terada T
Int J Clin Exp Pathol 2013;6(1):91-6. Epub 2012 Nov 20 PMID: 23236547Free PMC Article
Pathogenesis of carcinoma of the papilla of Vater.
Fischer HP, Zhou H
J Hepatobiliary Pancreat Surg 2004;11(5):301-9. doi: 10.1007/s00534-004-0898-3. PMID: 15549428
The homeobox intestinal differentiation factor CDX2 is selectively expressed in gastrointestinal adenocarcinomas.
Kaimaktchiev V, Terracciano L, Tornillo L, Spichtin H, Stoios D, Bundi M, Korcheva V, Mirlacher M, Loda M, Sauter G, Corless CL
Mod Pathol 2004 Nov;17(11):1392-9. doi: 10.1038/modpathol.3800205. PMID: 15205684
Mutation and altered expression of beta-catenin during gallbladder carcinogenesis.
Chang HJ, Jee CD, Kim WH
Am J Surg Pathol 2002 Jun;26(6):758-66. doi: 10.1097/00000478-200206000-00009. PMID: 12023580

Clinical prediction guides

The homeobox intestinal differentiation factor CDX2 is selectively expressed in gastrointestinal adenocarcinomas.
Kaimaktchiev V, Terracciano L, Tornillo L, Spichtin H, Stoios D, Bundi M, Korcheva V, Mirlacher M, Loda M, Sauter G, Corless CL
Mod Pathol 2004 Nov;17(11):1392-9. doi: 10.1038/modpathol.3800205. PMID: 15205684
p53 and Ki-67 immunoreactivity and nuclear morphometry of 'carcinoma-in-adenoma' and adenoma of the gall-bladder.
Takei K, Watanabe H, Itoi T, Saito T
Pathol Int 1996 Nov;46(11):908-17. doi: 10.1111/j.1440-1827.1996.tb03569.x. PMID: 8970203
p53 and Ki-67 immunoreactivity and nuclear morphometry of 'carcinoma-in-adenoma' and adenoma of the gall-bladder.
Takei K, Watanabe H, Itoi T, Saito T
Pathol Int 1996 Jun;46(6):426-35. doi: 10.1111/j.1440-1827.1996.tb03633.x. PMID: 8869994

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