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t(11;17)

MedGen UID:
1781679
•Concept ID:
C5446636
•
Cell or Molecular Dysfunction

Definition

A cytogenetic abnormality that involves a translocation between chromosomes 11 and 17. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVt(11;17)

Professional guidelines

PubMed

Low dose venetoclax as a single agent treatment of plasma cell malignancies harboring t(11;14).
Nahi H, Kashif M, Klimkowska M, Karvouni M, Wallblom A, Gran C, Hauenstein J, Frengen N, Gustafsson C, Afram G, Uttervall K, Lund J, Månsson R, Wagner AK, Alici E
Am J Hematol 2021 Aug 1;96(8):925-933. Epub 2021 May 18 doi: 10.1002/ajh.26207. PMID: 33901326
Clinical features and treatment outcomes of pediatric acute promyelocytic leukemia in a Mexican pediatric hospital.
Dorantes-Acosta E, Medina-Sanson A, Jaimes-García Y, López-Martínez B
Rev Invest Clin 2013 Sep-Oct;65(5):392-8. PMID: 24687338
Retinoic acid and acute promyelocytic leukemia: a model of targetting treatment for human cancer.
Chen Z, Chen SJ, Wang ZY
C R Acad Sci III 1994 Dec;317(12):1135-41. PMID: 7697468

Recent clinical studies

Diagnosis

Variant Acute Promyelocytic Leukemia Presenting Without Auer Rods Highlights the Need for Correlation with Cytogenetic Data in Leukemia Diagnosis.
Courville EL, Shantzer L, Vitzthum von Eckstaedt HC, Mellot H, Keng M, Sen J, Morris A, Williams E, El Chaer F
Lab Med 2022 Jan 6;53(1):95-99. doi: 10.1093/labmed/lmab051. PMID: 34268555

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