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Cervical Florid Reactive Lymphoid Hyperplasia

MedGen UID:
1793795
Concept ID:
C5557354
Pathologic Function

Definition

A dense, superficial benign lymphoid cell proliferation in the cervix. It almost always occurs in premenopausal women. It is composed of a mixture of large and small lymphocytes including immunoblasts. Plasma cells and neutrophils are also present. Immunohistochemical studies reveal a mixture of B and T lymphocytes, and polytypic plasma cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCervical Florid Reactive Lymphoid Hyperplasia

Recent clinical studies

Etiology

Ramalingam P, Zoroquiain P, Valbuena JR, Kemp BL, Medeiros LJ
Ann Diagn Pathol 2012 Jan;16(1):21-8. Epub 2011 Nov 4 doi: 10.1016/j.anndiagpath.2011.08.004. PMID: 22056039
Kojima M, Nakamura S, Shimizu K, Itoh H, Yoshida K, Hosomura Y, Yamane N, Ban S, Joshita T, Suchi T
Pathol Res Pract 1998;194(6):391-7. doi: 10.1016/S0344-0338(98)80029-0. PMID: 9689647
Ferry JA, Zukerberg LR, Harris NL
Am J Surg Pathol 1992 Mar;16(3):252-8. PMID: 1599017

Diagnosis

Ramalingam P, Zoroquiain P, Valbuena JR, Kemp BL, Medeiros LJ
Ann Diagn Pathol 2012 Jan;16(1):21-8. Epub 2011 Nov 4 doi: 10.1016/j.anndiagpath.2011.08.004. PMID: 22056039
Geyer JT, Ferry JA, Harris NL, Young RH, Longtine JA, Zukerberg LR
Am J Surg Pathol 2010 Feb;34(2):161-8. doi: 10.1097/PAS.0b013e3181cc4f12. PMID: 20087162
Kojima M, Motoori T, Iijima M, Ono T, Yoshizumi T, Matsumoto M, Masawa N, Nakamura S
Pathol Res Pract 2006;202(12):877-82. Epub 2006 Sep 20 doi: 10.1016/j.prp.2006.08.001. PMID: 16989959
Ferry JA, Zukerberg LR, Harris NL
Am J Surg Pathol 1992 Mar;16(3):252-8. PMID: 1599017

Prognosis

Ramalingam P, Zoroquiain P, Valbuena JR, Kemp BL, Medeiros LJ
Ann Diagn Pathol 2012 Jan;16(1):21-8. Epub 2011 Nov 4 doi: 10.1016/j.anndiagpath.2011.08.004. PMID: 22056039
Ferry JA, Zukerberg LR, Harris NL
Am J Surg Pathol 1992 Mar;16(3):252-8. PMID: 1599017

Clinical prediction guides

Kojima M, Motoori T, Iijima M, Ono T, Yoshizumi T, Matsumoto M, Masawa N, Nakamura S
Pathol Res Pract 2006;202(12):877-82. Epub 2006 Sep 20 doi: 10.1016/j.prp.2006.08.001. PMID: 16989959
Kojima M, Nakamura S, Shimizu K, Itoh H, Yoshida K, Hosomura Y, Yamane N, Ban S, Joshita T, Suchi T
Pathol Res Pract 1998;194(6):391-7. doi: 10.1016/S0344-0338(98)80029-0. PMID: 9689647

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