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Anti-centromere protein B antibody positivity

MedGen UID:
1814245
•Concept ID:
C5676675
•
Finding
Synonym: Anti-CENP-B antibody positivity
 
HPO: HP:0034079

Definition

The presence of autoantibodies (immunoglobulins) in the blood circulation that react against CENP-B. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnti-centromere protein B antibody positivity

Recent clinical studies

Prognosis

Multiple Autoimmune Syndrome: An Unusual Combination of Autoimmune Disorders.
Sarfaraz S, Anis S
Rev Recent Clin Trials 2020;15(3):240-243. doi: 10.2174/1574887115666200621184110. PMID: 32564761
Disease-related autoantibody profile in patients with systemic sclerosis.
Liaskos C, Marou E, Simopoulou T, Barmakoudi M, Efthymiou G, Scheper T, Meyer W, Bogdanos DP, Sakkas LI
Autoimmunity 2017 Nov;50(7):414-421. Epub 2017 Jul 27 doi: 10.1080/08916934.2017.1357699. PMID: 28749191
Relevance of clinical and autoantibody profiles in systemic sclerosis among Thais.
Foocharoen C, Watcharenwong P, Netwijitpan S, Mahakkanukrauh A, Suwannaroj S, Nanagara R
Int J Rheum Dis 2017 Oct;20(10):1572-1581. Epub 2017 Mar 10 doi: 10.1111/1756-185X.13060. PMID: 28296274
Anti-CENP-B antibodies are associated with prolonged survival in breast cancer.
Atalay C, Dogan L, Atalay G
Future Oncol 2010 Mar;6(3):471-7. doi: 10.2217/fon.10.6. PMID: 20222802
cDNA cloning of a novel autoantigen targeted by a minor subset of anti-centromere antibodies.
Muro Y, Yamada T, Himeno M, Sugimoto K
Clin Exp Immunol 1998 Feb;111(2):372-6. doi: 10.1046/j.1365-2249.1998.00517.x. PMID: 9486406Free PMC Article

Clinical prediction guides

Clinical Performance of the Line Immunoassay, Digital Liquid Chip Method, and Chemiluminescent Immunoassay for Detecting Specific Antinuclear Antibodies.
Su Z, Wang L, Gao X, Huang Z, Hu J, Yang B
Arch Pathol Lab Med 2024 May 1;148(5):566-572. doi: 10.5858/arpa.2022-0331-OA. PMID: 37594897
Disease-related autoantibody profile in patients with systemic sclerosis.
Liaskos C, Marou E, Simopoulou T, Barmakoudi M, Efthymiou G, Scheper T, Meyer W, Bogdanos DP, Sakkas LI
Autoimmunity 2017 Nov;50(7):414-421. Epub 2017 Jul 27 doi: 10.1080/08916934.2017.1357699. PMID: 28749191
Relevance of clinical and autoantibody profiles in systemic sclerosis among Thais.
Foocharoen C, Watcharenwong P, Netwijitpan S, Mahakkanukrauh A, Suwannaroj S, Nanagara R
Int J Rheum Dis 2017 Oct;20(10):1572-1581. Epub 2017 Mar 10 doi: 10.1111/1756-185X.13060. PMID: 28296274
Clinical and serological evaluation of a novel CENP-A peptide based ELISA.
Mahler M, Maes L, Blockmans D, Westhovens R, Bossuyt X, Riemekasten G, Schneider S, Hiepe F, Swart A, Gürtler I, Egerer K, Fooke M, Fritzler MJ
Arthritis Res Ther 2010;12(3):R99. Epub 2010 May 20 doi: 10.1186/ar3029. PMID: 20487535Free PMC Article
cDNA cloning of a novel autoantigen targeted by a minor subset of anti-centromere antibodies.
Muro Y, Yamada T, Himeno M, Sugimoto K
Clin Exp Immunol 1998 Feb;111(2):372-6. doi: 10.1046/j.1365-2249.1998.00517.x. PMID: 9486406Free PMC Article

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