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Elevated circulating rT3/T3 ratio

MedGen UID:
1815051
Concept ID:
C5706145
Finding
HPO: HP:0034289

Definition

An abnormally increased ratio of the concentrations of reverse T3 to T3 in the blood circulation. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVElevated circulating rT3/T3 ratio

Conditions with this feature

Thyroid hormone metabolism, abnormal, 2
MedGen UID:
1812066
Concept ID:
C5676976
Finding
Abnormal thyroid hormone metabolism-2 (THMA2) is characterized by elevated serum reverse triiodothyronine (rT3) levels and rT3/T3 ratios. Some patients exhibit resistance to thyroid-stimulating hormone (TSH; see 188540) with mildly elevated TSH levels, and elevated cholesterol levels have been observed (Franca et al., 2021). For a discussion of genetic heterogeneity of abnormal thyroid hormone metabolism, see THMA1 (609698).

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