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Pancreatic Duct Stenosis

MedGen UID:
181726
•Concept ID:
C0940747
•
Disease or Syndrome

Definition

Narrowing of the lumen of the pancreatic duct. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPancreatic Duct Stenosis

Professional guidelines

PubMed

Role of advanced endoscopy in the management of inflammatory digestive diseases (pancreas and biliary tract).
Ueki T, Maruo T, Igarashi Y, Yamamiya A, Tominaga K, Irisawa A, Yoshida H, Kamisawa T, Takenaka M, Isayama H
Dig Endosc 2024 May;36(5):546-553. Epub 2024 Mar 12 doi: 10.1111/den.14756. PMID: 38475671
Pancreatic duct stenosis: Differential diagnosis between malignant and benign conditions at secretin-enhanced MRCP.
Boninsegna E, Manfredi R, Negrelli R, Avesani G, Mehrabi S, Pozzi Mucelli R
Clin Imaging 2017 Jan-Feb;41:137-143. Epub 2016 Oct 29 doi: 10.1016/j.clinimag.2016.10.020. PMID: 27840266
New developments in diagnosis and non-surgical treatment of chronic pancreatitis.
Inui K, Yoshino J, Miyoshi H, Yamamoto S, Kobayashi T
J Gastroenterol Hepatol 2013 Dec;28 Suppl 4:108-12. doi: 10.1111/jgh.12250. PMID: 24251715

Recent clinical studies

Etiology

Incidence, Risk Factors, and Treatment of Proximally Migrated Pancreatic Stents.
Gokbulut V, Kaplan M, Odemis B, Disibeyaz S, Parlak E, Kilic ZMY, Oztas E
Surg Laparosc Endosc Percutan Tech 2021 Jun 23;31(6):697-702. doi: 10.1097/SLE.0000000000000966. PMID: 34166326
Pancreatic duct stenosis: Differential diagnosis between malignant and benign conditions at secretin-enhanced MRCP.
Boninsegna E, Manfredi R, Negrelli R, Avesani G, Mehrabi S, Pozzi Mucelli R
Clin Imaging 2017 Jan-Feb;41:137-143. Epub 2016 Oct 29 doi: 10.1016/j.clinimag.2016.10.020. PMID: 27840266
New developments in diagnosis and non-surgical treatment of chronic pancreatitis.
Inui K, Yoshino J, Miyoshi H, Yamamoto S, Kobayashi T
J Gastroenterol Hepatol 2013 Dec;28 Suppl 4:108-12. doi: 10.1111/jgh.12250. PMID: 24251715
Pancreatic duct stenosis secondary to small endocrine neoplasms: a manifestation of serotonin production?
Shi C, Siegelman SS, Kawamoto S, Wolfgang CL, Schulick RD, Maitra A, Hruban RH
Radiology 2010 Oct;257(1):107-14. Epub 2010 Aug 16 doi: 10.1148/radiol.10100046. PMID: 20713615Free PMC Article
Endoscopic therapy for stenosis of the biliary and pancreatic duct orifices.
Khandekar S, Disario JA
Gastrointest Endosc 2000 Oct;52(4):500-5. doi: 10.1067/mge.2000.108715. PMID: 11023567

Diagnosis

Secretin-Enhanced MRCP: How and Why-AJR Expert Panel Narrative Review.
Swensson J, Zaheer A, Conwell D, Sandrasegaran K, Manfredi R, Tirkes T
AJR Am J Roentgenol 2021 May;216(5):1139-1149. Epub 2021 Mar 11 doi: 10.2214/AJR.20.24857. PMID: 33263419Free PMC Article
Pancreatic duct stenosis: Differential diagnosis between malignant and benign conditions at secretin-enhanced MRCP.
Boninsegna E, Manfredi R, Negrelli R, Avesani G, Mehrabi S, Pozzi Mucelli R
Clin Imaging 2017 Jan-Feb;41:137-143. Epub 2016 Oct 29 doi: 10.1016/j.clinimag.2016.10.020. PMID: 27840266
New developments in diagnosis and non-surgical treatment of chronic pancreatitis.
Inui K, Yoshino J, Miyoshi H, Yamamoto S, Kobayashi T
J Gastroenterol Hepatol 2013 Dec;28 Suppl 4:108-12. doi: 10.1111/jgh.12250. PMID: 24251715
26. Pain in chronic pancreatitis.
Puylaert M, Kapural L, Van Zundert J, Peek D, Lataster A, Mekhail N, van Kleef M, Keulemans YC
Pain Pract 2011 Sep-Oct;11(5):492-505. Epub 2011 Jun 16 doi: 10.1111/j.1533-2500.2011.00474.x. PMID: 21676159
Endoscopic therapy for stenosis of the biliary and pancreatic duct orifices.
Khandekar S, Disario JA
Gastrointest Endosc 2000 Oct;52(4):500-5. doi: 10.1067/mge.2000.108715. PMID: 11023567

Therapy

Endoscopic Ultrasound Can Differentiate High-Grade Pancreatic Intraepithelial Neoplasia, Small Pancreatic Ductal Adenocarcinoma, and Benign Stenosis.
Sagami R, Yamao K, Minami R, Nakahodo J, Akiyama H, Nishikiori H, Mizukami K, Yamao K, Bhatia V, Amano Y, Murakami K
Gut Liver 2024 Mar 15;18(2):338-347. Epub 2023 May 11 doi: 10.5009/gnl220521. PMID: 37165770Free PMC Article
Secretin-Enhanced MRCP: How and Why-AJR Expert Panel Narrative Review.
Swensson J, Zaheer A, Conwell D, Sandrasegaran K, Manfredi R, Tirkes T
AJR Am J Roentgenol 2021 May;216(5):1139-1149. Epub 2021 Mar 11 doi: 10.2214/AJR.20.24857. PMID: 33263419Free PMC Article
Prophylactic pancreatic duct stenting in severe acute necrotizing pancreatitis: a prospective randomized study.
Karjula H, Nordblad Schmidt P, Mäkelä J, Liisanantti JH, Ohtonen P, Saarela A
Endoscopy 2019 Nov;51(11):1027-1034. Epub 2019 Mar 20 doi: 10.1055/a-0865-1960. PMID: 30895583
Pancreatic Pseudocysts and Parenchymal Necrosis in Patients With Autoimmune Pancreatitis: A Systematic Review.
Donet JA, Barkin JA, Keihanian T, Nemeth Z, Barkin JS
Pancreas 2018 Sep;47(8):952-957. doi: 10.1097/MPA.0000000000001121. PMID: 30028447
26. Pain in chronic pancreatitis.
Puylaert M, Kapural L, Van Zundert J, Peek D, Lataster A, Mekhail N, van Kleef M, Keulemans YC
Pain Pract 2011 Sep-Oct;11(5):492-505. Epub 2011 Jun 16 doi: 10.1111/j.1533-2500.2011.00474.x. PMID: 21676159

Prognosis

Incidence, Risk Factors, and Treatment of Proximally Migrated Pancreatic Stents.
Gokbulut V, Kaplan M, Odemis B, Disibeyaz S, Parlak E, Kilic ZMY, Oztas E
Surg Laparosc Endosc Percutan Tech 2021 Jun 23;31(6):697-702. doi: 10.1097/SLE.0000000000000966. PMID: 34166326
Prophylactic pancreatic duct stenting in severe acute necrotizing pancreatitis: a prospective randomized study.
Karjula H, Nordblad Schmidt P, Mäkelä J, Liisanantti JH, Ohtonen P, Saarela A
Endoscopy 2019 Nov;51(11):1027-1034. Epub 2019 Mar 20 doi: 10.1055/a-0865-1960. PMID: 30895583
Comparison between Endoscopic Treatment and Surgical Drainage of the Pancreatic Duct in Chronic Pancreatitis.
Kawashima Y, Kawaguchi Y, Kawanishi A, Ogawa M, Hirabayashi K, Nakagohri T, Mine T
Tokai J Exp Clin Med 2018 Sep 20;43(3):117-121. PMID: 30191547
Establishment and Verification of a Scoring Model for the Differential Diagnosis of Pancreatic Cancer and Chronic Pancreatitis.
Zhang H, Han W, Jin M, Lai Y, Wang X, Wang J, Yao Y, Wu D, Qian J, Yang H
Pancreas 2018 Apr;47(4):459-465. doi: 10.1097/MPA.0000000000001029. PMID: 29517635
Chronic pancreatitis and inflammatory bowel disease: true or coincidental association?
Barthet M, Hastier P, Bernard JP, Bordes G, Frederick J, Allio S, Mambrini P, Saint-Paul MC, Delmont JP, Salducci J, Grimaud JC, Sahel J
Am J Gastroenterol 1999 Aug;94(8):2141-8. doi: 10.1111/j.1572-0241.1999.01287.x. PMID: 10445541

Clinical prediction guides

Endoscopic Ultrasound Can Differentiate High-Grade Pancreatic Intraepithelial Neoplasia, Small Pancreatic Ductal Adenocarcinoma, and Benign Stenosis.
Sagami R, Yamao K, Minami R, Nakahodo J, Akiyama H, Nishikiori H, Mizukami K, Yamao K, Bhatia V, Amano Y, Murakami K
Gut Liver 2024 Mar 15;18(2):338-347. Epub 2023 May 11 doi: 10.5009/gnl220521. PMID: 37165770Free PMC Article
Comparison between Endoscopic Treatment and Surgical Drainage of the Pancreatic Duct in Chronic Pancreatitis.
Kawashima Y, Kawaguchi Y, Kawanishi A, Ogawa M, Hirabayashi K, Nakagohri T, Mine T
Tokai J Exp Clin Med 2018 Sep 20;43(3):117-121. PMID: 30191547
Pancreatic Pseudocysts and Parenchymal Necrosis in Patients With Autoimmune Pancreatitis: A Systematic Review.
Donet JA, Barkin JA, Keihanian T, Nemeth Z, Barkin JS
Pancreas 2018 Sep;47(8):952-957. doi: 10.1097/MPA.0000000000001121. PMID: 30028447
Establishment and Verification of a Scoring Model for the Differential Diagnosis of Pancreatic Cancer and Chronic Pancreatitis.
Zhang H, Han W, Jin M, Lai Y, Wang X, Wang J, Yao Y, Wu D, Qian J, Yang H
Pancreas 2018 Apr;47(4):459-465. doi: 10.1097/MPA.0000000000001029. PMID: 29517635
A case of concurrent pancreatic intraepithelial neoplasia and type 1 autoimmune pancreatitis with marked pancreatic duct dilatation.
Takano Y, Nagahama M, Yamamura E, Maruoka N, Yokomizo K, Mizukami H, Tanaka J, Ohike N
Clin J Gastroenterol 2016 Aug;9(4):266-71. Epub 2016 Jun 28 doi: 10.1007/s12328-016-0666-3. PMID: 27351197

Recent systematic reviews

Pancreatic Pseudocysts and Parenchymal Necrosis in Patients With Autoimmune Pancreatitis: A Systematic Review.
Donet JA, Barkin JA, Keihanian T, Nemeth Z, Barkin JS
Pancreas 2018 Sep;47(8):952-957. doi: 10.1097/MPA.0000000000001121. PMID: 30028447

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