Elevated CSF angiotensin-converting enzyme concentration

MedGen UID:: 1841616
•Concept ID:: C5826376
•: Finding

Synonyms:	Angiotensin-converting enzyme (ACE) high in CSF; Angiotensin-converting enzyme high in CSF

HPO:	HP:0034406

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GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVElevated CSF angiotensin-converting enzyme concentration

Congenital Systemic Disorder
- Abnormality of the nervous system
  - Abnormal nervous system morphology
    - Morphological central nervous system abnormality
      - Abnormal cerebrospinal fluid morphology
        Abnormal CSF protein concentration
        Elevated CSF angiotensin-converting enzyme concentration

Recent clinical studies

Etiology

Cerebrospinal fluid levels of angiotensin-converting enzyme, acetylcholinesterase, and dopamine metabolites in dementia associated with Alzheimer's disease and Parkinson's disease: a correlative study.

Zubenko GS, Marquis JK, Volicer L, Direnfeld LK, Langlais PJ, Nixon RA
Biol Psychiatry 1986 Dec;21(14):1365-81. doi: 10.1016/0006-3223(86)90328-8. PMID: 3024746

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Therapy

Acute oral captopril inhibits angiotensin converting enzyme activity in human cerebrospinal fluid.

Geppetti P, Spillantini MG, Frilli S, Pietrini U, Fanciullacci M, Sicuteri F
J Hypertens 1987 Apr;5(2):151-4. doi: 10.1097/00004872-198704000-00004. PMID: 3038992

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Clinical prediction guides

Acute oral captopril inhibits angiotensin converting enzyme activity in human cerebrospinal fluid.

Geppetti P, Spillantini MG, Frilli S, Pietrini U, Fanciullacci M, Sicuteri F
J Hypertens 1987 Apr;5(2):151-4. doi: 10.1097/00004872-198704000-00004. PMID: 3038992

Zubenko GS, Marquis JK, Volicer L, Direnfeld LK, Langlais PJ, Nixon RA
Biol Psychiatry 1986 Dec;21(14):1365-81. doi: 10.1016/0006-3223(86)90328-8. PMID: 3024746

Assay and biochemical characterization of angiotensin-I-converting enzyme in cerebrospinal fluid.

Schweisfurth H, Schiöberg-Schiegnitz S
Enzyme 1984;32(1):12-9. doi: 10.1159/000469445. PMID: 6090116

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Elevated CSF angiotensin-converting enzyme concentration

Term Hierarchy

Recent clinical studies

Etiology

Therapy

Clinical prediction guides

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