U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Partial deletion of the short arm of chromosome 9

MedGen UID:
1842163
•Concept ID:
C5679669
•
Cell or Molecular Dysfunction
Synonym: Chromosome 9, partial monosomy 9p
 
Orphanet: ORPHA261929

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPartial deletion of the short arm of chromosome 9

Recent clinical studies

Etiology

Abnormal gonadal differentiation in two subjects with ambiguous genitalia, Mullerian structures, and normally developed testes: evidence for a defect in gonadal ridge development.
Fuqua JS, Sher ES, Perlman EJ, Urban MD, Ghahremani M, Pelletier J, Migeon CJ, Brown TR, Berkovitz GD
Hum Genet 1996 Apr;97(4):506-11. doi: 10.1007/BF02267076. PMID: 8834252
Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia.
Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO
Genomics 1992 Oct;14(2):437-43. doi: 10.1016/s0888-7543(05)80238-1. PMID: 1385305

Diagnosis

Unbalanced translocation involving partial trisomy 9p and partial monosomy yq with neurodevelopmental delays.
Lyons MJ, Fuller JD, Montoya Mdel C, DuPont BR, Holden KR
J Child Neurol 2013 Apr;28(4):524-6. Epub 2012 Jun 29 doi: 10.1177/0883073812446309. PMID: 22752474
Complex rearrangement involving 9p deletion and duplication in a syndromic patient: genotype/phenotype correlation and review of the literature.
Recalcati MP, Bellini M, Norsa L, Ballarati L, Caselli R, Russo S, Larizza L, Giardino D
Gene 2012 Jul 1;502(1):40-5. Epub 2012 Apr 17 doi: 10.1016/j.gene.2012.04.030. PMID: 22537675
Partial deletion 9p syndrome in Malaysian children.
Chew HB, Thong MK
Med J Malaysia 2010 Sep;65(3):215-7. PMID: 21939171
4p- syndrome and 9p tetrasomy mosaicism with cleft lip and palate.
Kobayashi J, Kimijima Y, Yamada S, Amagasa T, Saito-Ohara F
J Craniomaxillofac Surg 2000 Jun;28(3):165-70. doi: 10.1054/jcms.2000.0126. PMID: 10964553
T-cell acute lymphoblastic leukaemia with late developing Philadelphia chromosome.
Miller BA, Reid MM, Nell M, Lipton JM, Sallan SE, Nathan DG, Tantravahi R
Br J Haematol 1984 Jan;56(1):139-46. doi: 10.1111/j.1365-2141.1984.tb01279.x. PMID: 6608369

Prognosis

Unbalanced translocation involving partial trisomy 9p and partial monosomy yq with neurodevelopmental delays.
Lyons MJ, Fuller JD, Montoya Mdel C, DuPont BR, Holden KR
J Child Neurol 2013 Apr;28(4):524-6. Epub 2012 Jun 29 doi: 10.1177/0883073812446309. PMID: 22752474
Partial deletion 9p syndrome in Malaysian children.
Chew HB, Thong MK
Med J Malaysia 2010 Sep;65(3):215-7. PMID: 21939171
4p- syndrome and 9p tetrasomy mosaicism with cleft lip and palate.
Kobayashi J, Kimijima Y, Yamada S, Amagasa T, Saito-Ohara F
J Craniomaxillofac Surg 2000 Jun;28(3):165-70. doi: 10.1054/jcms.2000.0126. PMID: 10964553
Acute lymphocytic leukemia with 9p anomalies. A report of four additional cases and review of the literature.
Laï JL, Fenaux P, Pollet JP, Estienne MH, Savary JB, Huart JJ, Deminatti M
Cancer Genet Cytogenet 1988 Jul 1;33(1):99-109. doi: 10.1016/0165-4608(88)90055-6. PMID: 3289733
Abnormalities of the short arm of chromosome 9 with partial loss of material in hematological disorders.
Pollak C, Hagemeijer A
Leukemia 1987 Jul;1(7):541-8. PMID: 3312844

Clinical prediction guides

Codeletion of CDKN2 and MTAP genes in a subset of non-Hodgkin's lymphoma may be associated with histologic transformation from low-grade to diffuse large-cell lymphoma.
Dreyling MH, Roulston D, Bohlander SK, Vardiman J, Olopade OI
Genes Chromosomes Cancer 1998 May;22(1):72-8. PMID: 9591637
Molecular cytogenetics of human papillomavirus-negative cervical carcinoma cell lines.
Zimonjic DB, Simpson S, Popescu NC, DiPaolo JA
Cancer Genet Cytogenet 1995 Jul 1;82(1):1-8. doi: 10.1016/0165-4608(95)91129-7. PMID: 7627928
Molecular and cytogenetic analysis of chromosome 9 deletions in 75 malignant gliomas.
Bello MJ, de Campos JM, Vaquero J, Kusak ME, Sarasa JL, Pestaña A, Rey JA
Genes Chromosomes Cancer 1994 Jan;9(1):33-41. doi: 10.1002/gcc.2870090107. PMID: 7507698
Molecular analysis of deletions of the short arm of chromosome 9 in human gliomas.
Olopade OI, Jenkins RB, Ransom DT, Malik K, Pomykala H, Nobori T, Cowan JM, Rowley JD, Diaz MO
Cancer Res 1992 May 1;52(9):2523-9. PMID: 1568221
Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia.
Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO
Genomics 1992 Oct;14(2):437-43. doi: 10.1016/s0888-7543(05)80238-1. PMID: 1385305

Supplemental Content

Table of contents

    Genetic Testing Registry

    Clinical resources

    Consumer resources

    Reviews

    Related information

    • GTR
      Related information in GTR
    • GTR(Clinical)
      Clinical tests in GTR
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...