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Anti-ADAMTS13 antibody positivity

MedGen UID:
1864286
•Concept ID:
C5937231
•
Laboratory or Test Result
HPO: HP:6000462

Definition

The presence of autoantibodies (immunoglobulins) in the blood circulation that react against A Disintegrin and Metalloprotease with ThromboSpondin type 1 repeats, member 13 (ADAMTS13). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnti-ADAMTS13 antibody positivity

Professional guidelines

PubMed

Diagnostic and treatment guidelines for thrombotic thrombocytopenic purpura (TTP) in Japan 2023.
Matsumoto M, Miyakawa Y, Kokame K, Ueda Y, Wada H, Higasa S, Yagi H, Ogawa Y, Sakai K, Miyata T, Morishita E, Fujimura Y; For TTP group of Blood Coagulation Abnormalities Research Study Team, Research on Rare and Intractable diseases, Health and Labour Sciences Research Grants from the Ministry of Health, Labour and Welfare of Japan
Int J Hematol 2023 Nov;118(5):529-546. Epub 2023 Sep 10 doi: 10.1007/s12185-023-03657-0. PMID: 37689812Free PMC Article
Diagnostic and treatment guidelines for thrombotic thrombocytopenic purpura (TTP) 2017 in Japan.
Matsumoto M, Fujimura Y, Wada H, Kokame K, Miyakawa Y, Ueda Y, Higasa S, Moriki T, Yagi H, Miyata T, Murata M; For TTP group of Blood Coagulation Abnormalities Research Team, Research on Rare and Intractable Disease supported by Health, Labour, and Welfare Sciences Research Grants
Int J Hematol 2017 Jul;106(1):3-15. Epub 2017 May 26 doi: 10.1007/s12185-017-2264-7. PMID: 28550351

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