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Castration anxiety complex

MedGen UID:
1998
•Concept ID:
C0003476
•
Mental or Behavioral Dysfunction
Synonyms: Anxiety, Castration; Castration Anxiety; Castration Complex; Castration Complices; Complex, Castration; Complices, Castration
SNOMED CT: Castration anxiety complex (304896009)

Definition

Anxiety due to fantasized injuries to or loss of the genitals. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCastration anxiety complex

Professional guidelines

PubMed

Clinical course and treatment outcome of Koro: A follow up study from a Koro epidemic reported from West Bengal, India.
Dan A, Mondal T, Chakraborty K, Chaudhuri A, Biswas A
Asian J Psychiatr 2017 Apr;26:14-20. Epub 2016 Dec 30 doi: 10.1016/j.ajp.2016.12.016. PMID: 28483078
The psychoanalytic treatment of a preschool boy with a gender identity disorder.
Haber CH
J Am Psychoanal Assoc 1991;39(1):107-29. doi: 10.1177/000306519103900106. PMID: 2026849
Transsexualism--problems in treatment.
Baker HJ
Am J Psychiatry 1969 Apr;125(10):1412-8. doi: 10.1176/ajp.125.10.1412. PMID: 5772926

Recent clinical studies

Etiology

"How His Hair is Growing Thin!": On the Emotional Significance of Male Pattern Hair Loss.
Wooldridge T
J Am Psychoanal Assoc 2023 Apr;71(2):215-236. doi: 10.1177/00030651231170529. PMID: 37357928
Mental health care utilization among men with castration-resistant prostate cancer receiving abiraterone or enzalutamide.
Tsao PA, Burns J, Kumbier K, Sparks JB, Entenman S, Bloor LE, Bohnert ASB, Skolarus TA, Caram MEV
Cancer Med 2023 Aug;12(15):16490-16501. Epub 2023 Jun 16 doi: 10.1002/cam4.6237. PMID: 37325888Free PMC Article
Castration anxiety.
Appel JM
J Bioeth Inq 2012 Mar;9(1):85-91. Epub 2011 Dec 22 doi: 10.1007/s11673-011-9341-z. PMID: 23180204
Koro--the psychological disappearance of the penis.
Mattelaer JJ, Jilek W
J Sex Med 2007 Sep;4(5):1509-15. doi: 10.1111/j.1743-6109.2007.00586.x. PMID: 17727356
Vasectomy.
Qureshi F
Aust Fam Physician 1984 Oct;13(10):734-5, 737. PMID: 6508643

Diagnosis

Sexual differentiation of neural mechanisms of stress sensitivity during puberty.
Wright EC, Luo PX, Zakharenkov HC, Serna Godoy A, Lake AA, Prince ZD, Sekar S, Culkin HI, Ramirez AV, Dwyer T, Kapoor A, Corbett C, Tian L, Fox AS, Trainor BC
Proc Natl Acad Sci U S A 2023 Oct 24;120(43):e2306475120. Epub 2023 Oct 17 doi: 10.1073/pnas.2306475120. PMID: 37847733Free PMC Article
Sexual Motivation and Sexual Reward in Male Rats are Attenuated by the Gonadotropin-Releasing Hormone Receptor Antagonist Degarelix.
Hawley WR, Kapp LE, Dingle CM, Dufala HA, Green PA, Barnes JL, Barwell JL
J Sex Med 2021 Feb;18(2):240-255. Epub 2021 Jan 6 doi: 10.1016/j.jsxm.2020.11.004. PMID: 33419705
Symptoms and Impacts in Non-Metastatic Castration-Resistant Prostate Cancer: Qualitative Study Findings.
Tomaszewski EL, Moise P, Krupnick RN, Downing J, Meyer M, Naidoo S, Holmstrom S
Patient 2017 Oct;10(5):567-578. doi: 10.1007/s40271-017-0227-y. PMID: 28285412Free PMC Article
Castration.
Rangell L
J Am Psychoanal Assoc 1991;39(1):3-23. doi: 10.1177/000306519103900101. PMID: 2026855
The depressive character.
Kahn E
Folia Psychiatr Neurol Jpn 1975;29(4):291-303. doi: 10.1111/j.1440-1819.1975.tb02347.x. PMID: 1232040

Therapy

Mental health care utilization among men with castration-resistant prostate cancer receiving abiraterone or enzalutamide.
Tsao PA, Burns J, Kumbier K, Sparks JB, Entenman S, Bloor LE, Bohnert ASB, Skolarus TA, Caram MEV
Cancer Med 2023 Aug;12(15):16490-16501. Epub 2023 Jun 16 doi: 10.1002/cam4.6237. PMID: 37325888Free PMC Article
Effects of Androgen Deprivation Therapy on Pain Perception, Quality of Life, and Depression in Men With Prostate Cancer.
Gagliano-Jucá T, Travison TG, Nguyen PL, Kantoff PW, Taplin ME, Kibel AS, Manley R, Hally K, Bearup R, Beleva YM, Huang G, Edwards RR, Basaria S
J Pain Symptom Manage 2018 Feb;55(2):307-317.e1. Epub 2017 Sep 21 doi: 10.1016/j.jpainsymman.2017.09.017. PMID: 28941963Free PMC Article
Symptoms and Impacts in Non-Metastatic Castration-Resistant Prostate Cancer: Qualitative Study Findings.
Tomaszewski EL, Moise P, Krupnick RN, Downing J, Meyer M, Naidoo S, Holmstrom S
Patient 2017 Oct;10(5):567-578. doi: 10.1007/s40271-017-0227-y. PMID: 28285412Free PMC Article
Castration anxiety.
Appel JM
J Bioeth Inq 2012 Mar;9(1):85-91. Epub 2011 Dec 22 doi: 10.1007/s11673-011-9341-z. PMID: 23180204
Vasectomy.
Qureshi F
Aust Fam Physician 1984 Oct;13(10):734-5, 737. PMID: 6508643

Prognosis

Sexual Function After Voluntary Castration.
Wibowo E, Wong STS, Wassersug RJ, Johnson TW
Arch Sex Behav 2021 Nov;50(8):3889-3899. Epub 2021 Oct 26 doi: 10.1007/s10508-021-02094-6. PMID: 34704159
Tarasca: ritual monster of Spain.
Gilmore DD
Proc Am Philos Soc 2008 Sep;152(3):362-82. PMID: 19831233
Indecent exposure and exhibitionism.
Rooth FG
Br J Psychiatry 1975;Spec No 9:212-22. PMID: 1102016
Impotence.
Johnson J
Br J Psychiatry 1975;Spec No 9:206-11. PMID: 171019
Psychological reactions to hysterectomy: a critical review.
Polivy J
Am J Obstet Gynecol 1974 Feb 1;118(3):417-26. doi: 10.1016/s0002-9378(16)33802-9. PMID: 4599392

Clinical prediction guides

Koro: a socially-transmitted delusional belief.
Coltheart M, Davies M
Cogn Neuropsychiatry 2024 Jan;29(1):10-28. Epub 2024 Feb 13 doi: 10.1080/13546805.2024.2313474. PMID: 38348821
Sexual Function After Voluntary Castration.
Wibowo E, Wong STS, Wassersug RJ, Johnson TW
Arch Sex Behav 2021 Nov;50(8):3889-3899. Epub 2021 Oct 26 doi: 10.1007/s10508-021-02094-6. PMID: 34704159
Phallic and seminal masculinity: a theoretical and clinical confusion.
Figlio K
Int J Psychoanal 2010 Feb;91(1):119-39. doi: 10.1111/j.1745-8315.2009.00215.x. PMID: 20433478
Health-related quality-of-life assessments in patients with advanced cancer of the prostate.
Adolfsson J
Pharmacoeconomics 2003;21(4):241-7. doi: 10.2165/00019053-200321040-00002. PMID: 12600219
Single spies and battalions: the clinical epidemiology of mental disorders.
Cooper B
Psychol Med 1993 Nov;23(4):891-907. doi: 10.1017/s0033291700026362. PMID: 8134513

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