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Intestinal Stoma Leakage

MedGen UID:
216045
•Concept ID:
C1142488
•
Pathologic Function

Definition

Leakage of contents from the intestinal stoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntestinal Stoma Leakage

Professional guidelines

PubMed

Treatment of anastomotic leakage after rectal cancer resection: The TENTACLE-Rectum study.
van Workum F, Talboom K, Hannink G, Wolthuis A, de Lacy BF, Lefevre JH, Solomon M, Frasson M, Rotholtz N, Denost Q, Perez RO, Konishi T, Panis Y, Rosman C, Hompes R, Tanis PJ, de Wilt JHW
Colorectal Dis 2021 Apr;23(4):982-988. Epub 2020 Dec 26 doi: 10.1111/codi.15435. PMID: 33169512Free PMC Article
Recurrence of rectal anastomotic leakage following stoma closure: assessment of risk factors.
Kitaguchi D, Nishizawa Y, Sasaki T, Tsukada Y, Ikeda K, Ito M
Colorectal Dis 2019 Nov;21(11):1304-1311. Epub 2019 Jul 7 doi: 10.1111/codi.14728. PMID: 31199545
Considerations for the management of enterocutaneous fistula.
Metcalf C
Br J Nurs 2019 Mar 14;28(5):S24-S31. doi: 10.12968/bjon.2019.28.5.S24. PMID: 30907655

Recent clinical studies

Etiology

Anastomotic leakage and functional outcomes following total mesorectal excision with delayed and immediate colo-anal anastomosis for rectal cancer: Two single-arm phase II trials.
Evrard S, Bellera C, Desolneux G, Cantarel C, Toulza E, Faucheron JL, Rivoire M, Dupré A, Mabrut JY, Bresler L, Marchal F, Bouriez D, Rullier E
Eur J Surg Oncol 2023 Nov;49(11):107015. Epub 2023 Oct 23 doi: 10.1016/j.ejso.2023.107015. PMID: 37949519
Stoma-free Survival After Rectal Cancer Resection With Anastomotic Leakage: Development and Validation of a Prediction Model in a Large International Cohort.
Greijdanus NG, Wienholts K, Ubels S, Talboom K, Hannink G, Wolthuis A, de Lacy FB, Lefevre JH, Solomon M, Frasson M, Rotholtz N, Denost Q, Perez RO, Konishi T, Panis Y, Rutegård M, Hompes R, Rosman C, van Workum F, Tanis PJ, de Wilt JHW; TENTACLE-Rectum Collaborative Group
Ann Surg 2023 Nov 1;278(5):772-780. Epub 2023 Jul 27 doi: 10.1097/SLA.0000000000006043. PMID: 37498208Free PMC Article
Predictive factors for anastomotic leakage after laparoscopic colorectal surgery.
Sciuto A, Merola G, De Palma GD, Sodo M, Pirozzi F, Bracale UM, Bracale U
World J Gastroenterol 2018 Jun 7;24(21):2247-2260. doi: 10.3748/wjg.v24.i21.2247. PMID: 29881234Free PMC Article
A Cross-sectional Study of Nutritional Status, Diet, and Dietary Restrictions Among Persons With an Ileostomy or Colostomy.
de Oliveira AL, Boroni Moreira AP, Pereira Netto M, Gonçalves Leite IC
Ostomy Wound Manage 2018 May;64(5):18-29. PMID: 29847308
Sigmoidostomy-related parastomal hernia.
Wik TA, Hjorthaug JO, Johannessen HO, Johnson E
Scand J Surg 2011;100(3):186-9. doi: 10.1177/145749691110000309. PMID: 22108747

Diagnosis

Cost associated with diverting ostomy after rectal cancer surgery: a transnational analysis.
Geisler BP, Cao KN, Ryschon AM, Alavi K, Komen N, Pietzsch JB
Surg Endosc 2023 Oct;37(10):7759-7766. Epub 2023 Aug 14 doi: 10.1007/s00464-023-10300-w. PMID: 37580581
Stoma-free Survival After Rectal Cancer Resection With Anastomotic Leakage: Development and Validation of a Prediction Model in a Large International Cohort.
Greijdanus NG, Wienholts K, Ubels S, Talboom K, Hannink G, Wolthuis A, de Lacy FB, Lefevre JH, Solomon M, Frasson M, Rotholtz N, Denost Q, Perez RO, Konishi T, Panis Y, Rutegård M, Hompes R, Rosman C, van Workum F, Tanis PJ, de Wilt JHW; TENTACLE-Rectum Collaborative Group
Ann Surg 2023 Nov 1;278(5):772-780. Epub 2023 Jul 27 doi: 10.1097/SLA.0000000000006043. PMID: 37498208Free PMC Article
The fate of preserved sphincter in rectal cancer patients.
Yoo RN, Kim G, Kye BH, Cho HM, Kim H
Int J Colorectal Dis 2018 Jun;33(6):745-753. Epub 2018 Mar 12 doi: 10.1007/s00384-018-3001-2. PMID: 29532208
Late leakage after anterior resection: a defunctioning stoma alters the clinical course of anastomotic leakage.
Jutesten H, Draus J, Frey J, Neovius G, Lindmark G, Buchwald P, Lydrup ML
Colorectal Dis 2018 Feb;20(2):150-159. doi: 10.1111/codi.13914. PMID: 29024481
Predicting the risk and diminishing the consequences of anastomotic leakage after anterior resection for rectal cancer.
Moran BJ
Acta Chir Iugosl 2010;57(3):47-50. doi: 10.2298/aci1003047m. PMID: 21066983

Therapy

Anastomotic leakage and functional outcomes following total mesorectal excision with delayed and immediate colo-anal anastomosis for rectal cancer: Two single-arm phase II trials.
Evrard S, Bellera C, Desolneux G, Cantarel C, Toulza E, Faucheron JL, Rivoire M, Dupré A, Mabrut JY, Bresler L, Marchal F, Bouriez D, Rullier E
Eur J Surg Oncol 2023 Nov;49(11):107015. Epub 2023 Oct 23 doi: 10.1016/j.ejso.2023.107015. PMID: 37949519
Reducing anastomotic leak in colorectal surgery: The old dogmas and the new challenges.
Meyer J, Naiken S, Christou N, Liot E, Toso C, Buchs NC, Ris F
World J Gastroenterol 2019 Sep 14;25(34):5017-5025. doi: 10.3748/wjg.v25.i34.5017. PMID: 31558854Free PMC Article
Predictive factors for anastomotic leakage after laparoscopic colorectal surgery.
Sciuto A, Merola G, De Palma GD, Sodo M, Pirozzi F, Bracale UM, Bracale U
World J Gastroenterol 2018 Jun 7;24(21):2247-2260. doi: 10.3748/wjg.v24.i21.2247. PMID: 29881234Free PMC Article
Techniques for colorectal anastomosis.
Ho YH, Ashour MA
World J Gastroenterol 2010 Apr 7;16(13):1610-21. doi: 10.3748/wjg.v16.i13.1610. PMID: 20355239Free PMC Article
Surgical complications of urinary diversion.
Farnham SB, Cookson MS
World J Urol 2004 Sep;22(3):157-67. Epub 2004 Aug 13 doi: 10.1007/s00345-004-0429-5. PMID: 15316737

Prognosis

Meta-analysis: loop ileostomy versus colostomy to prevent complications of anterior resection for rectal cancer.
Yang S, Tang G, Zhang Y, Wei Z, Du D
Int J Colorectal Dis 2024 May 8;39(1):68. doi: 10.1007/s00384-024-04639-2. PMID: 38714581Free PMC Article
Stoma-free Survival After Rectal Cancer Resection With Anastomotic Leakage: Development and Validation of a Prediction Model in a Large International Cohort.
Greijdanus NG, Wienholts K, Ubels S, Talboom K, Hannink G, Wolthuis A, de Lacy FB, Lefevre JH, Solomon M, Frasson M, Rotholtz N, Denost Q, Perez RO, Konishi T, Panis Y, Rutegård M, Hompes R, Rosman C, van Workum F, Tanis PJ, de Wilt JHW; TENTACLE-Rectum Collaborative Group
Ann Surg 2023 Nov 1;278(5):772-780. Epub 2023 Jul 27 doi: 10.1097/SLA.0000000000006043. PMID: 37498208Free PMC Article
Reducing anastomotic leak in colorectal surgery: The old dogmas and the new challenges.
Meyer J, Naiken S, Christou N, Liot E, Toso C, Buchs NC, Ris F
World J Gastroenterol 2019 Sep 14;25(34):5017-5025. doi: 10.3748/wjg.v25.i34.5017. PMID: 31558854Free PMC Article
Predictive factors for anastomotic leakage after laparoscopic colorectal surgery.
Sciuto A, Merola G, De Palma GD, Sodo M, Pirozzi F, Bracale UM, Bracale U
World J Gastroenterol 2018 Jun 7;24(21):2247-2260. doi: 10.3748/wjg.v24.i21.2247. PMID: 29881234Free PMC Article
Decision-making in rectal surgery.
MacDermid E, Young CJ, Young J, Solomon M
Colorectal Dis 2014 Mar;16(3):203-8. doi: 10.1111/codi.12487. PMID: 24521275

Clinical prediction guides

Anastomotic leakage and functional outcomes following total mesorectal excision with delayed and immediate colo-anal anastomosis for rectal cancer: Two single-arm phase II trials.
Evrard S, Bellera C, Desolneux G, Cantarel C, Toulza E, Faucheron JL, Rivoire M, Dupré A, Mabrut JY, Bresler L, Marchal F, Bouriez D, Rullier E
Eur J Surg Oncol 2023 Nov;49(11):107015. Epub 2023 Oct 23 doi: 10.1016/j.ejso.2023.107015. PMID: 37949519
Stoma-free Survival After Rectal Cancer Resection With Anastomotic Leakage: Development and Validation of a Prediction Model in a Large International Cohort.
Greijdanus NG, Wienholts K, Ubels S, Talboom K, Hannink G, Wolthuis A, de Lacy FB, Lefevre JH, Solomon M, Frasson M, Rotholtz N, Denost Q, Perez RO, Konishi T, Panis Y, Rutegård M, Hompes R, Rosman C, van Workum F, Tanis PJ, de Wilt JHW; TENTACLE-Rectum Collaborative Group
Ann Surg 2023 Nov 1;278(5):772-780. Epub 2023 Jul 27 doi: 10.1097/SLA.0000000000006043. PMID: 37498208Free PMC Article
Predictive factors for anastomotic leakage after laparoscopic colorectal surgery.
Sciuto A, Merola G, De Palma GD, Sodo M, Pirozzi F, Bracale UM, Bracale U
World J Gastroenterol 2018 Jun 7;24(21):2247-2260. doi: 10.3748/wjg.v24.i21.2247. PMID: 29881234Free PMC Article
A Cross-sectional Study of Nutritional Status, Diet, and Dietary Restrictions Among Persons With an Ileostomy or Colostomy.
de Oliveira AL, Boroni Moreira AP, Pereira Netto M, Gonçalves Leite IC
Ostomy Wound Manage 2018 May;64(5):18-29. PMID: 29847308
Decision-making in rectal surgery.
MacDermid E, Young CJ, Young J, Solomon M
Colorectal Dis 2014 Mar;16(3):203-8. doi: 10.1111/codi.12487. PMID: 24521275

Recent systematic reviews

The effect of preoperative stoma site marking on risk of stoma-related complications in patients with intestinal ostomy - A systematic review and meta-analysis.
Ambe PC, Kugler CM, Breuing J, Grohmann E, Friedel J, Hess S, Pieper D
Colorectal Dis 2022 Aug;24(8):904-917. Epub 2022 Apr 6 doi: 10.1111/codi.16118. PMID: 35297146
Ileorectal anastomosis in patients with Crohn's disease. Postoperative complications and functional outcome-a systematic review.
Baelum JK, Qvist N, Ellebaek MB
Colorectal Dis 2021 Oct;23(10):2501-2514. Epub 2021 Aug 10 doi: 10.1111/codi.15839. PMID: 34309170
Safety and efficacy of endoscopic colonic stenting as a bridge to surgery in the management of intestinal obstruction due to left colon and rectal cancer: a systematic review and meta-analysis.
Cirocchi R, Farinella E, Trastulli S, Desiderio J, Listorti C, Boselli C, Parisi A, Noya G, Sagar J
Surg Oncol 2013 Mar;22(1):14-21. Epub 2012 Nov 24 doi: 10.1016/j.suronc.2012.10.003. PMID: 23183301
Covering ileo- or colostomy in anterior resection for rectal carcinoma.
Montedori A, Cirocchi R, Farinella E, Sciannameo F, Abraha I
Cochrane Database Syst Rev 2010 May 12;(5):CD006878. doi: 10.1002/14651858.CD006878.pub2. PMID: 20464746
Loop ileostomy versus loop colostomy for fecal diversion after colorectal or coloanal anastomosis: a meta-analysis.
Rondelli F, Reboldi P, Rulli A, Barberini F, Guerrisi A, Izzo L, Bolognese A, Covarelli P, Boselli C, Becattini C, Noya G
Int J Colorectal Dis 2009 May;24(5):479-88. Epub 2009 Feb 12 doi: 10.1007/s00384-009-0662-x. PMID: 19219439

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