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Posterior uveitis

MedGen UID:
22597
•Concept ID:
C0042167
•
Disease or Syndrome
Synonyms: Posterior Uveitis; Uveitis, Posterior
SNOMED CT: Posterior uveitis (43363007)
 
HPO: HP:0012123
Monarch Initiative: MONDO:0006918

Definition

Inflammation of the uveal tract in which the primary site of inflammation is the retina or choroid. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPosterior uveitis
Follow this link to review classifications for Posterior uveitis in Orphanet.

Conditions with this feature

Birdshot chorioretinopathy
MedGen UID:
340098
•Concept ID:
C1853959
•
Disease or Syndrome
Multiple cream-yellow colored hypopigmented lesions typically located at the level of the choroid or retinal pigment epithelium; ovoid, cream-colored with indistinct borders. They are between 50 and 1,500 micrometers in size with a characteristic nasal, radial distribution in the postequatorial fundus.
See: Condition Record
Birdshot chorioretinopathy

Professional guidelines

PubMed

Classification Criteria for Behçet Disease Uveitis.
Standardization of Uveitis Nomenclature (SUN) Working Group
Am J Ophthalmol 2021 Aug;228:80-88. Epub 2021 May 11 doi: 10.1016/j.ajo.2021.03.058. PMID: 33845008Free PMC Article
Recent advances in the management of non-infectious posterior uveitis.
Singh RB, Sinha S, Saini C, Elbasiony E, Thakur S, Agarwal A
Int Ophthalmol 2020 Nov;40(11):3187-3207. Epub 2020 Jul 2 doi: 10.1007/s10792-020-01496-0. PMID: 32617804
Recent Developments in the Diagnosis and Treatment of Ocular Toxoplasmosis.
Ozgonul C, Besirli CG
Ophthalmic Res 2017;57(1):1-12. Epub 2016 Oct 11 doi: 10.1159/000449169. PMID: 27723657

Recent clinical studies

Etiology

Ocular Toxoplasmosis.
Goh EJH, Putera I, La Distia Nora R, Mahendradas P, Biswas J, Chee SP, Testi I, Pavesio CE, Curi ALL, Vasconcelos-Santos DV, Arora A, Gupta V, de-la-Torre A, Agrawal R
Ocul Immunol Inflamm 2023 Sep;31(7):1342-1361. Epub 2022 Sep 12 doi: 10.1080/09273948.2022.2117705. PMID: 36095008
Classification Criteria for Behçet Disease Uveitis.
Standardization of Uveitis Nomenclature (SUN) Working Group
Am J Ophthalmol 2021 Aug;228:80-88. Epub 2021 May 11 doi: 10.1016/j.ajo.2021.03.058. PMID: 33845008Free PMC Article
Toxoplasmosis and behavioural changes.
Desmettre T
J Fr Ophtalmol 2020 Mar;43(3):e89-e93. Epub 2020 Jan 21 doi: 10.1016/j.jfo.2020.01.001. PMID: 31980266
A Focus on the Epidemiology of Uveitis.
Tsirouki T, Dastiridou A, Symeonidis C, Tounakaki O, Brazitikou I, Kalogeropoulos C, Androudi S
Ocul Immunol Inflamm 2018;26(1):2-16. Epub 2016 Jul 28 doi: 10.1080/09273948.2016.1196713. PMID: 27467180
Viral posterior uveitis.
Lee JH, Agarwal A, Mahendradas P, Lee CS, Gupta V, Pavesio CE, Agrawal R
Surv Ophthalmol 2017 Jul-Aug;62(4):404-445. Epub 2016 Dec 22 doi: 10.1016/j.survophthal.2016.12.008. PMID: 28012878Free PMC Article

Diagnosis

Behçet Syndrome.
Hatemi G, Uçar D, Uygunoğlu U, Yazici H, Yazici Y
Rheum Dis Clin North Am 2023 Aug;49(3):585-602. Epub 2023 May 2 doi: 10.1016/j.rdc.2023.03.010. PMID: 37331734
Ocular toxoplasmosis: a review of the current diagnostic and therapeutic approaches.
Kalogeropoulos D, Sakkas H, Mohammed B, Vartholomatos G, Malamos K, Sreekantam S, Kanavaros P, Kalogeropoulos C
Int Ophthalmol 2022 Jan;42(1):295-321. Epub 2021 Aug 9 doi: 10.1007/s10792-021-01994-9. PMID: 34370174Free PMC Article
Vaccine-Associated Posterior Uveitis.
Cunningham ET Jr, Moorthy RS
Retin Cases Brief Rep 2022 Jan 1;16(1):1-4. doi: 10.1097/ICB.0000000000000958. PMID: 31971925
Sarcoidosis.
Salah S, Abad S, Monnet D, Brézin AP
J Fr Ophtalmol 2018 Dec;41(10):e451-e467. Epub 2018 Nov 16 doi: 10.1016/j.jfo.2018.10.002. PMID: 30449643
Viral posterior uveitis.
Lee JH, Agarwal A, Mahendradas P, Lee CS, Gupta V, Pavesio CE, Agrawal R
Surv Ophthalmol 2017 Jul-Aug;62(4):404-445. Epub 2016 Dec 22 doi: 10.1016/j.survophthal.2016.12.008. PMID: 28012878Free PMC Article

Therapy

Ocular Sarcoidosis.
Sève P, Jamilloux Y, Tilikete C, Gerfaud-Valentin M, Kodjikian L, El Jammal T
Semin Respir Crit Care Med 2020 Oct;41(5):673-688. Epub 2020 Aug 10 doi: 10.1055/s-0040-1710536. PMID: 32777852
Vaccine-Associated Posterior Uveitis.
Cunningham ET Jr, Moorthy RS
Retina 2020 Apr;40(4):595-598. doi: 10.1097/IAE.0000000000002816. PMID: 32221173
Adalimumab in Patients with Active Noninfectious Uveitis.
Jaffe GJ, Dick AD, Brézin AP, Nguyen QD, Thorne JE, Kestelyn P, Barisani-Asenbauer T, Franco P, Heiligenhaus A, Scales D, Chu DS, Camez A, Kwatra NV, Song AP, Kron M, Tari S, Suhler EB
N Engl J Med 2016 Sep 8;375(10):932-43. doi: 10.1056/NEJMoa1509852. PMID: 27602665
Posterior Uveitis.
Uy HS, Yu-Keh E, Chan PS
Dev Ophthalmol 2016;55:163-6. Epub 2015 Oct 26 doi: 10.1159/000438968. PMID: 26502276
Dengue eye disease.
Ng AW, Teoh SC
Surv Ophthalmol 2015 Mar-Apr;60(2):106-14. Epub 2014 Aug 12 doi: 10.1016/j.survophthal.2014.07.003. PMID: 25223497

Prognosis

Behçet Syndrome.
Hatemi G, Uçar D, Uygunoğlu U, Yazici H, Yazici Y
Rheum Dis Clin North Am 2023 Aug;49(3):585-602. Epub 2023 May 2 doi: 10.1016/j.rdc.2023.03.010. PMID: 37331734
Ocular Sarcoidosis.
Sève P, Jamilloux Y, Tilikete C, Gerfaud-Valentin M, Kodjikian L, El Jammal T
Semin Respir Crit Care Med 2020 Oct;41(5):673-688. Epub 2020 Aug 10 doi: 10.1055/s-0040-1710536. PMID: 32777852
Toxoplasmosis and behavioural changes.
Desmettre T
J Fr Ophtalmol 2020 Mar;43(3):e89-e93. Epub 2020 Jan 21 doi: 10.1016/j.jfo.2020.01.001. PMID: 31980266
A Focus on the Epidemiology of Uveitis.
Tsirouki T, Dastiridou A, Symeonidis C, Tounakaki O, Brazitikou I, Kalogeropoulos C, Androudi S
Ocul Immunol Inflamm 2018;26(1):2-16. Epub 2016 Jul 28 doi: 10.1080/09273948.2016.1196713. PMID: 27467180
Viral posterior uveitis.
Lee JH, Agarwal A, Mahendradas P, Lee CS, Gupta V, Pavesio CE, Agrawal R
Surv Ophthalmol 2017 Jul-Aug;62(4):404-445. Epub 2016 Dec 22 doi: 10.1016/j.survophthal.2016.12.008. PMID: 28012878Free PMC Article

Clinical prediction guides

Toxoplasmosis and behavioural changes.
Desmettre T
J Fr Ophtalmol 2020 Mar;43(3):e89-e93. Epub 2020 Jan 21 doi: 10.1016/j.jfo.2020.01.001. PMID: 31980266
Demographic and Clinical Features of Pediatric Uveitis in Israel.
Habot-Wilner Z, Tiosano L, Sanchez JM, Shulman S, Barequet D, Rahat O, Amarilyo G, Amer R
Ocul Immunol Inflamm 2020;28(1):43-53. Epub 2018 Oct 17 doi: 10.1080/09273948.2018.1535079. PMID: 30332547
Punctate inner choroidopathy: A review.
Ahnood D, Madhusudhan S, Tsaloumas MD, Waheed NK, Keane PA, Denniston AK
Surv Ophthalmol 2017 Mar-Apr;62(2):113-126. Epub 2016 Oct 15 doi: 10.1016/j.survophthal.2016.10.003. PMID: 27751823
Fundus autofluorescence imaging in posterior uveitis.
Durrani K, Foster CS
Semin Ophthalmol 2012 Sep-Nov;27(5-6):228-35. doi: 10.3109/08820538.2012.711414. PMID: 23163281
Chorioretinitis in infants.
Modrzejewska M, Lachowicz E, Karczewicz D, Zdanowska A
Klin Oczna 2011;113(10-12):352-6. PMID: 22384654

Recent systematic reviews

Corticosteroid implants for chronic non-infectious uveitis.
Reddy A, Liu SH, Brady CJ, Sieving PC, Palestine AG
Cochrane Database Syst Rev 2023 Aug 29;8(8):CD010469. doi: 10.1002/14651858.CD010469.pub4. PMID: 37642198Free PMC Article
A Systematic Review of Clinical Trials in Uveitis: Lessons Learned.
Lobo-Chan AM, Joltikov K, Haseeb A, Mehta SD
Ophthalmic Epidemiol 2023 Oct;30(5):445-452. Epub 2022 Oct 6 doi: 10.1080/09286586.2022.2131837. PMID: 36204817Free PMC Article
Tubulointerstitial nephritis and uveitis syndrome: a systematic review.
Regusci A, Lava SAG, Milani GP, Bianchetti MG, Simonetti GD, Vanoni F
Nephrol Dial Transplant 2022 Apr 25;37(5):876-886. doi: 10.1093/ndt/gfab030. PMID: 33561271
Ocular Manifestations in Rheumatoid Arthritis, Connective Tissue Disease, and Vasculitis: A Systematic Review and Metaanalysis.
Turk MA, Hayworth JL, Nevskaya T, Pope JE
J Rheumatol 2021 Jan 1;48(1):25-34. Epub 2020 May 1 doi: 10.3899/jrheum.190768. PMID: 32358156
Uveitis: a global perspective.
Chang JH, Wakefield D
Ocul Immunol Inflamm 2002 Dec;10(4):263-79. doi: 10.1076/ocii.10.4.263.15592. PMID: 12854035

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