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Abdominal bloating

MedGen UID:
226938
•Concept ID:
C1291077
•
Sign or Symptom
Synonym: Bloating
SNOMED CT: Abdominal bloating (116289008); Bloated abdomen (116289008)

Definition

Distention of the abdomen associated with a feeling of fullness. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbdominal bloating

Professional guidelines

PubMed

Management of Chronic Abdominal Distension and Bloating.
Lacy BE, Cangemi D, Vazquez-Roque M
Clin Gastroenterol Hepatol 2021 Feb;19(2):219-231.e1. Epub 2020 Apr 1 doi: 10.1016/j.cgh.2020.03.056. PMID: 32246999
Small Intestinal Bacterial Overgrowth: Clinical Features and Therapeutic Management.
Rao SSC, Bhagatwala J
Clin Transl Gastroenterol 2019 Oct;10(10):e00078. doi: 10.14309/ctg.0000000000000078. PMID: 31584459Free PMC Article
Diagnosis and Treatment of Peptic Ulcer Disease.
Kavitt RT, Lipowska AM, Anyane-Yeboa A, Gralnek IM
Am J Med 2019 Apr;132(4):447-456. Epub 2019 Jan 3 doi: 10.1016/j.amjmed.2018.12.009. PMID: 30611829

Recent clinical studies

Etiology

AGA Clinical Practice Update on Evaluation and Management of Belching, Abdominal Bloating, and Distention: Expert Review.
Moshiree B, Drossman D, Shaukat A
Gastroenterology 2023 Sep;165(3):791-800.e3. Epub 2023 Jul 13 doi: 10.1053/j.gastro.2023.04.039. PMID: 37452811
Epidemiology of small intestinal bacterial overgrowth.
Efremova I, Maslennikov R, Poluektova E, Vasilieva E, Zharikov Y, Suslov A, Letyagina Y, Kozlov E, Levshina A, Ivashkin V
World J Gastroenterol 2023 Jun 14;29(22):3400-3421. doi: 10.3748/wjg.v29.i22.3400. PMID: 37389240Free PMC Article
Efficacy of a low FODMAP diet in irritable bowel syndrome: systematic review and network meta-analysis.
Black CJ, Staudacher HM, Ford AC
Gut 2022 Jun;71(6):1117-1126. Epub 2021 Aug 10 doi: 10.1136/gutjnl-2021-325214. PMID: 34376515
Small Intestinal Bacterial Overgrowth: Clinical Features and Therapeutic Management.
Rao SSC, Bhagatwala J
Clin Transl Gastroenterol 2019 Oct;10(10):e00078. doi: 10.14309/ctg.0000000000000078. PMID: 31584459Free PMC Article
Constipation: Pathophysiology and Current Therapeutic Approaches.
Sharma A, Rao S
Handb Exp Pharmacol 2017;239:59-74. doi: 10.1007/164_2016_111. PMID: 28185025

Diagnosis

AGA Clinical Practice Update on Evaluation and Management of Belching, Abdominal Bloating, and Distention: Expert Review.
Moshiree B, Drossman D, Shaukat A
Gastroenterology 2023 Sep;165(3):791-800.e3. Epub 2023 Jul 13 doi: 10.1053/j.gastro.2023.04.039. PMID: 37452811
Management of bloating.
Serra J
Neurogastroenterol Motil 2022 Mar;34(3):e14333. Epub 2022 Feb 10 doi: 10.1111/nmo.14333. PMID: 35143108
Management of Chronic Abdominal Distension and Bloating.
Lacy BE, Cangemi D, Vazquez-Roque M
Clin Gastroenterol Hepatol 2021 Feb;19(2):219-231.e1. Epub 2020 Apr 1 doi: 10.1016/j.cgh.2020.03.056. PMID: 32246999
Small Intestinal Bacterial Overgrowth: Clinical Features and Therapeutic Management.
Rao SSC, Bhagatwala J
Clin Transl Gastroenterol 2019 Oct;10(10):e00078. doi: 10.14309/ctg.0000000000000078. PMID: 31584459Free PMC Article
Constipation: Pathophysiology and Current Therapeutic Approaches.
Sharma A, Rao S
Handb Exp Pharmacol 2017;239:59-74. doi: 10.1007/164_2016_111. PMID: 28185025

Therapy

The Role of the FODMAP Diet in IBS.
Bertin L, Zanconato M, Crepaldi M, Marasco G, Cremon C, Barbara G, Barberio B, Zingone F, Savarino EV
Nutrients 2024 Jan 26;16(3) doi: 10.3390/nu16030370. PMID: 38337655Free PMC Article
Efficacy of a low FODMAP diet in irritable bowel syndrome: systematic review and network meta-analysis.
Black CJ, Staudacher HM, Ford AC
Gut 2022 Jun;71(6):1117-1126. Epub 2021 Aug 10 doi: 10.1136/gutjnl-2021-325214. PMID: 34376515
Small Intestinal Bacterial Overgrowth: Clinical Features and Therapeutic Management.
Rao SSC, Bhagatwala J
Clin Transl Gastroenterol 2019 Oct;10(10):e00078. doi: 10.14309/ctg.0000000000000078. PMID: 31584459Free PMC Article
Probiotics for the prevention of pediatric antibiotic-associated diarrhea.
Guo Q, Goldenberg JZ, Humphrey C, El Dib R, Johnston BC
Cochrane Database Syst Rev 2019 Apr 30;4(4):CD004827. doi: 10.1002/14651858.CD004827.pub5. PMID: 31039287Free PMC Article
Constipation: Pathophysiology and Current Therapeutic Approaches.
Sharma A, Rao S
Handb Exp Pharmacol 2017;239:59-74. doi: 10.1007/164_2016_111. PMID: 28185025

Prognosis

Epidemiology of small intestinal bacterial overgrowth.
Efremova I, Maslennikov R, Poluektova E, Vasilieva E, Zharikov Y, Suslov A, Letyagina Y, Kozlov E, Levshina A, Ivashkin V
World J Gastroenterol 2023 Jun 14;29(22):3400-3421. doi: 10.3748/wjg.v29.i22.3400. PMID: 37389240Free PMC Article
United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on functional dyspepsia.
Wauters L, Dickman R, Drug V, Mulak A, Serra J, Enck P, Tack J; ESNM FD Consensus Group, Accarino A, Barbara G, Bor S, Coffin B, Corsetti M, De Schepper H, Dumitrascu D, Farmer A, Gourcerol G, Hauser G, Hausken T, Karamanolis G, Keszthelyi D, Malagelada C, Milosavljevic T, Muris J, O'Morain C, Papathanasopoulos A, Pohl D, Rumyantseva D, Sarnelli G, Savarino E, Schol J, Sheptulin A, Smet A, Stengel A, Storonova O, Storr M, Törnblom H, Vanuytsel T, Velosa M, Waluga M, Zarate N, Zerbib F
United European Gastroenterol J 2021 Apr;9(3):307-331. doi: 10.1002/ueg2.12061. PMID: 33939891Free PMC Article
Effect of Acupuncture for Postprandial Distress Syndrome: A Randomized Clinical Trial.
Yang JW, Wang LQ, Zou X, Yan SY, Wang Y, Zhao JJ, Tu JF, Wang J, Shi GX, Hu H, Zhou W, Du Y, Liu CZ
Ann Intern Med 2020 Jun 16;172(12):777-785. Epub 2020 May 12 doi: 10.7326/M19-2880. PMID: 32422066
Small Intestinal Bacterial Overgrowth: Clinical Features and Therapeutic Management.
Rao SSC, Bhagatwala J
Clin Transl Gastroenterol 2019 Oct;10(10):e00078. doi: 10.14309/ctg.0000000000000078. PMID: 31584459Free PMC Article
Abdominal bloating and distension: what is the role of the microbiota.
Issa B, Wafaei NA, Whorwell PJ
Dig Dis Sci 2012 Jan;57(1):4-8. Epub 2011 Jul 29 doi: 10.1007/s10620-011-1834-4. PMID: 21800157

Clinical prediction guides

AGA Clinical Practice Update on Evaluation and Management of Belching, Abdominal Bloating, and Distention: Expert Review.
Moshiree B, Drossman D, Shaukat A
Gastroenterology 2023 Sep;165(3):791-800.e3. Epub 2023 Jul 13 doi: 10.1053/j.gastro.2023.04.039. PMID: 37452811
Antibiotics, gut microbiota, and irritable bowel syndrome: What are the relations?
Mamieva Z, Poluektova E, Svistushkin V, Sobolev V, Shifrin O, Guarner F, Ivashkin V
World J Gastroenterol 2022 Mar 28;28(12):1204-1219. doi: 10.3748/wjg.v28.i12.1204. PMID: 35431513Free PMC Article
Efficacy of a low FODMAP diet in irritable bowel syndrome: systematic review and network meta-analysis.
Black CJ, Staudacher HM, Ford AC
Gut 2022 Jun;71(6):1117-1126. Epub 2021 Aug 10 doi: 10.1136/gutjnl-2021-325214. PMID: 34376515
Small Intestinal Bacterial Overgrowth: Clinical Features and Therapeutic Management.
Rao SSC, Bhagatwala J
Clin Transl Gastroenterol 2019 Oct;10(10):e00078. doi: 10.14309/ctg.0000000000000078. PMID: 31584459Free PMC Article
Probiotics for the prevention of pediatric antibiotic-associated diarrhea.
Guo Q, Goldenberg JZ, Humphrey C, El Dib R, Johnston BC
Cochrane Database Syst Rev 2019 Apr 30;4(4):CD004827. doi: 10.1002/14651858.CD004827.pub5. PMID: 31039287Free PMC Article

Recent systematic reviews

Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis.
Xie P, Luo M, Deng X, Fan J, Xiong L
Nutrients 2023 Sep 4;15(17) doi: 10.3390/nu15173856. PMID: 37686889Free PMC Article
Efficacy of Probiotics in Irritable Bowel Syndrome: Systematic Review and Meta-analysis.
Goodoory VC, Khasawneh M, Black CJ, Quigley EMM, Moayyedi P, Ford AC
Gastroenterology 2023 Nov;165(5):1206-1218. Epub 2023 Aug 3 doi: 10.1053/j.gastro.2023.07.018. PMID: 37541528
Efficacy of a low FODMAP diet in irritable bowel syndrome: systematic review and network meta-analysis.
Black CJ, Staudacher HM, Ford AC
Gut 2022 Jun;71(6):1117-1126. Epub 2021 Aug 10 doi: 10.1136/gutjnl-2021-325214. PMID: 34376515
Systematic review and network meta-analysis: efficacy of licensed drugs for abdominal bloating in irritable bowel syndrome with constipation.
Nelson AD, Black CJ, Houghton LA, Lugo-Fagundo NS, Lacy BE, Ford AC
Aliment Pharmacol Ther 2021 Jul;54(2):98-108. Epub 2021 Jun 11 doi: 10.1111/apt.16437. PMID: 34114657
Probiotics for the prevention of pediatric antibiotic-associated diarrhea.
Guo Q, Goldenberg JZ, Humphrey C, El Dib R, Johnston BC
Cochrane Database Syst Rev 2019 Apr 30;4(4):CD004827. doi: 10.1002/14651858.CD004827.pub5. PMID: 31039287Free PMC Article

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