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Adult kidney Wilms tumor

MedGen UID:
231045
Concept ID:
C1332219
Neoplastic Process
Synonyms: Adenosarcoma of Adult Kidney; adenosarcoma of adult kidney; Adenosarcoma of the Adult Kidney; adenosarcoma of the adult kidney; Adult Kidney Adenosarcoma; adult kidney adenosarcoma; Adult Kidney Nephroblastoma; Adult Kidney Wilms Tumor; adult kidney Wilms tumor; adult nephroblastoma; Adult Renal Adenosarcoma; adult renal adenosarcoma; Adult Renal Wilms Tumor; adult renal Wilms tumor; adult renal Wilms tumour; Adult Renal Wilms' Tumor; adult renal Wilms' tumor; adult renal Wilms' tumour; kidney Wilms tumor of adults; kidney Wilms tumour of adults
 
Monarch Initiative: MONDO:0024675

Definition

Wilms tumor of the kidney which occurs in adults. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdult kidney Wilms tumor

Professional guidelines

PubMed

Jain AG, Talati C, Pinilla-Ibarz J
Expert Opin Investig Drugs 2021 Jun;30(6):595-601. Epub 2021 May 31 doi: 10.1080/13543784.2021.1928635. PMID: 34053383
Ino K, Fuji S, Tajima K, Tanaka T, Okinaka K, Inamoto Y, Kurosawa S, Kim SW, Katayama N, Fukuda T
Biol Blood Marrow Transplant 2017 Oct;23(10):1780-1787. Epub 2017 Jun 30 doi: 10.1016/j.bbmt.2017.06.007. PMID: 28673850
Segers H, van den Heuvel-Eibrink MM, Pritchard-Jones K, Coppes MJ, Aitchison M, Bergeron C, de Camargo B, Dome JS, Grundy P, Gatta G, Graf N, Grundy P, Kalapurakal JA, de Kraker J, Perlman EJ, Reinhard H, Spreafico F, Vujanic G, Warwick AB; SIOP-RTSG and the COG-Renal Tumour Committee
Expert Rev Anticancer Ther 2011 Jul;11(7):1105-13. doi: 10.1586/era.11.76. PMID: 21806333

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Wilms Tumor (Nephroblastoma), 2023

Recent clinical studies

Etiology

Ehrlich P, Chi YY, Chintagumpala MM, Hoffer FA, Perlman EJ, Kalapurakal JA, Warwick A, Shamberger RC, Khanna G, Hamilton TE, Gow KW, Paulino AC, Gratias EJ, Mullen EA, Geller JI, Grundy PE, Fernandez CV, Ritchey ML, Dome JS
Ann Surg 2017 Sep;266(3):470-478. doi: 10.1097/SLA.0000000000002356. PMID: 28795993Free PMC Article
Sadowski CE, Lovric S, Ashraf S, Pabst WL, Gee HY, Kohl S, Engelmann S, Vega-Warner V, Fang H, Halbritter J, Somers MJ, Tan W, Shril S, Fessi I, Lifton RP, Bockenhauer D, El-Desoky S, Kari JA, Zenker M, Kemper MJ, Mueller D, Fathy HM, Soliman NA; SRNS Study Group, Hildebrandt F
J Am Soc Nephrol 2015 Jun;26(6):1279-89. Epub 2014 Oct 27 doi: 10.1681/ASN.2014050489. PMID: 25349199Free PMC Article
Zdrojowy R, Sawicz-Birkowska K, Apoznański W, Patkowski D, Szydełko T, Pietras W, Dembowski J
Int Urol Nephrol 2011 Sep;43(3):691-6. Epub 2010 Nov 26 doi: 10.1007/s11255-010-9868-7. PMID: 21110097
Zahm SH, Ward MH
Environ Health Perspect 1998 Jun;106 Suppl 3(Suppl 3):893-908. doi: 10.1289/ehp.98106893. PMID: 9646054Free PMC Article
Donaldson SS
Int J Radiat Oncol Biol Phys 1993 Aug 1;26(5):739-49. doi: 10.1016/0360-3016(93)90487-g. PMID: 8344841

Diagnosis

Castle JT, Levy BE, Rodeberg DA
Surg Clin North Am 2022 Oct;102(5):715-737. Epub 2022 Sep 7 doi: 10.1016/j.suc.2022.07.006. PMID: 36209742
Kim J, Gianferante M, Karyadi DM, Hartley SW, Frone MN, Luo W, Robison LL, Armstrong GT, Bhatia S, Dean M, Yeager M, Zhu B, Song L, Sampson JN, Yasui Y, Leisenring WM, Brodie SA, de Andrade KC, Fortes FP, Goldstein AM, Khincha PP, Machiela MJ, McMaster ML, Nickerson ML, Oba L, Pemov A, Pinheiro M, Rotunno M, Santiago K, Wegman-Ostrosky T, Diver WR, Teras L, Freedman ND, Hicks BD, Zhu B, Wang M, Jones K, Hutchinson AA, Dagnall C, Savage SA, Tucker MA, Chanock SJ, Morton LM, Stewart DR, Mirabello L
JNCI Cancer Spectr 2021 Apr;5(2) Epub 2021 Jan 23 doi: 10.1093/jncics/pkab007. PMID: 34308104Free PMC Article
Calandrini C, Schutgens F, Oka R, Margaritis T, Candelli T, Mathijsen L, Ammerlaan C, van Ineveld RL, Derakhshan S, de Haan S, Dolman E, Lijnzaad P, Custers L, Begthel H, Kerstens HHD, Visser LL, Rookmaaker M, Verhaar M, Tytgat GAM, Kemmeren P, de Krijger RR, Al-Saadi R, Pritchard-Jones K, Kool M, Rios AC, van den Heuvel-Eibrink MM, Molenaar JJ, van Boxtel R, Holstege FCP, Clevers H, Drost J
Nat Commun 2020 Mar 11;11(1):1310. doi: 10.1038/s41467-020-15155-6. PMID: 32161258Free PMC Article
Neylon OM, Werther GA, Sabin MA
Curr Opin Pediatr 2012 Aug;24(4):505-11. doi: 10.1097/MOP.0b013e3283558995. PMID: 22705997
Zdrojowy R, Sawicz-Birkowska K, Apoznański W, Patkowski D, Szydełko T, Pietras W, Dembowski J
Int Urol Nephrol 2011 Sep;43(3):691-6. Epub 2010 Nov 26 doi: 10.1007/s11255-010-9868-7. PMID: 21110097

Therapy

Bhatia S, Tonorezos ES, Landier W
JAMA 2023 Sep 26;330(12):1175-1186. doi: 10.1001/jama.2023.16875. PMID: 37750876
Jain AG, Talati C, Pinilla-Ibarz J
Expert Opin Investig Drugs 2021 Jun;30(6):595-601. Epub 2021 May 31 doi: 10.1080/13543784.2021.1928635. PMID: 34053383
Ehrlich P, Chi YY, Chintagumpala MM, Hoffer FA, Perlman EJ, Kalapurakal JA, Warwick A, Shamberger RC, Khanna G, Hamilton TE, Gow KW, Paulino AC, Gratias EJ, Mullen EA, Geller JI, Grundy PE, Fernandez CV, Ritchey ML, Dome JS
Ann Surg 2017 Sep;266(3):470-478. doi: 10.1097/SLA.0000000000002356. PMID: 28795993Free PMC Article
Zdrojowy R, Sawicz-Birkowska K, Apoznański W, Patkowski D, Szydełko T, Pietras W, Dembowski J
Int Urol Nephrol 2011 Sep;43(3):691-6. Epub 2010 Nov 26 doi: 10.1007/s11255-010-9868-7. PMID: 21110097
Zahm SH, Ward MH
Environ Health Perspect 1998 Jun;106 Suppl 3(Suppl 3):893-908. doi: 10.1289/ehp.98106893. PMID: 9646054Free PMC Article

Prognosis

Wu NL, Chen Y, Dieffenbach BV, Ehrhardt MJ, Hingorani S, Howell RM, Jefferies JL, Mulrooney DA, Oeffinger KC, Robison LL, Weil BR, Yuan Y, Yasui Y, Hudson MM, Leisenring WM, Armstrong GT, Chow EJ
J Clin Oncol 2023 Apr 20;41(12):2258-2268. Epub 2023 Feb 16 doi: 10.1200/JCO.22.01926. PMID: 36795981Free PMC Article
Ehrlich P, Chi YY, Chintagumpala MM, Hoffer FA, Perlman EJ, Kalapurakal JA, Warwick A, Shamberger RC, Khanna G, Hamilton TE, Gow KW, Paulino AC, Gratias EJ, Mullen EA, Geller JI, Grundy PE, Fernandez CV, Ritchey ML, Dome JS
Ann Surg 2017 Sep;266(3):470-478. doi: 10.1097/SLA.0000000000002356. PMID: 28795993Free PMC Article
Sadowski CE, Lovric S, Ashraf S, Pabst WL, Gee HY, Kohl S, Engelmann S, Vega-Warner V, Fang H, Halbritter J, Somers MJ, Tan W, Shril S, Fessi I, Lifton RP, Bockenhauer D, El-Desoky S, Kari JA, Zenker M, Kemper MJ, Mueller D, Fathy HM, Soliman NA; SRNS Study Group, Hildebrandt F
J Am Soc Nephrol 2015 Jun;26(6):1279-89. Epub 2014 Oct 27 doi: 10.1681/ASN.2014050489. PMID: 25349199Free PMC Article
Neylon OM, Werther GA, Sabin MA
Curr Opin Pediatr 2012 Aug;24(4):505-11. doi: 10.1097/MOP.0b013e3283558995. PMID: 22705997
Ottaviani G, Jaffe N
Cancer Treat Res 2009;152:3-13. doi: 10.1007/978-1-4419-0284-9_1. PMID: 20213383

Clinical prediction guides

Bhatia S, Tonorezos ES, Landier W
JAMA 2023 Sep 26;330(12):1175-1186. doi: 10.1001/jama.2023.16875. PMID: 37750876
Sehgal M, Jain V, Agarwala S, Dhua A, Goel P, Yadav DK, Bakhshi S, Kalaivani M
Nutr Cancer 2023;75(9):1795-1802. Epub 2023 Aug 6 doi: 10.1080/01635581.2023.2242104. PMID: 37545131
Venkataramany AS, Schieffer KM, Lee K, Cottrell CE, Wang PY, Mardis ER, Cripe TP, Chandler DS
Ann Oncol 2022 Jun;33(6):578-592. Epub 2022 Mar 23 doi: 10.1016/j.annonc.2022.03.011. PMID: 35339647
Zahm SH, Ward MH
Environ Health Perspect 1998 Jun;106 Suppl 3(Suppl 3):893-908. doi: 10.1289/ehp.98106893. PMID: 9646054Free PMC Article
Donaldson SS
Int J Radiat Oncol Biol Phys 1993 Aug 1;26(5):739-49. doi: 10.1016/0360-3016(93)90487-g. PMID: 8344841

Recent systematic reviews

Doganis D, Katsimpris A, Panagopoulou P, Bouka P, Bouka E, Moschovi M, Polychronopoulou S, Papakonstantinou E, Tragiannidis A, Katzilakis N, Dana H, Antoniadi K, Stefanaki K, Strantzia K, Dessypris N, Schüz J, Petridou ET
Cancer Epidemiol 2020 Aug;67:101769. Epub 2020 Jul 10 doi: 10.1016/j.canep.2020.101769. PMID: 32659726
Malek MM, Behr CA, Aldrink JH, Dasgupta R, Heaton TE, Gehred A, Lautz TB, Baertschiger RM, Christison-Lagay ER, Tracy ET, Rhee DS, Rodeberg D, Austin MT, Ehrlich PF
J Pediatr Surg 2020 Nov;55(11):2251-2259. Epub 2020 Mar 31 doi: 10.1016/j.jpedsurg.2020.03.019. PMID: 32386972
Gómez FM, Patel PA, Stuart S, Roebuck DJ
Pediatr Radiol 2014 Oct;44(10):1281-9. Epub 2014 May 13 doi: 10.1007/s00247-014-3001-5. PMID: 24821394

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2023
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Wilms Tumor (Nephroblastoma), 2023

    Consumer resources

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