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Bone angiosarcoma

MedGen UID:
231448
•Concept ID:
C1332574
•
Neoplastic Process
Synonyms: angiosarcoma (disease) of bone tissue; Bone Angioendothelial Sarcoma; bone angioendothelial sarcoma; Bone Angiosarcoma; bone angiosarcoma; Bone Hemangioendothelial Sarcoma; bone Hemangioendothelial sarcoma; Bone Hemangiosarcoma; bone hemangiosarcoma; bone tissue angiosarcoma (disease); Osseous Angioendothelial Sarcoma; osseous angioendothelial sarcoma; Osseous Angiosarcoma; osseous angiosarcoma; Osseous Hemangiosarcoma; osseous hemangiosarcoma
 
Monarch Initiative: MONDO:0002617

Definition

A high-grade malignant vascular neoplasm that arises from the bone. It is characterized by the presence of neoplastic cells with endothelial differentiation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBone angiosarcoma

Professional guidelines

PubMed

A Clinical Model of Bone Angiosarcoma Patients: A Population-based Analysis of Epidemiology, Prognosis, and Treatment.
Wang B, Chen LJ, Wang XY
Orthop Surg 2020 Dec;12(6):1652-1662. Epub 2020 Sep 10 doi: 10.1111/os.12803. PMID: 32914587Free PMC Article

Recent clinical studies

Etiology

A Clinical Model of Bone Angiosarcoma Patients: A Population-based Analysis of Epidemiology, Prognosis, and Treatment.
Wang B, Chen LJ, Wang XY
Orthop Surg 2020 Dec;12(6):1652-1662. Epub 2020 Sep 10 doi: 10.1111/os.12803. PMID: 32914587Free PMC Article
Active TGF-β signaling and decreased expression of PTEN separates angiosarcoma of bone from its soft tissue counterpart.
Verbeke SL, Bertoni F, Bacchini P, Oosting J, Sciot R, Krenács T, Bovée JV
Mod Pathol 2013 Sep;26(9):1211-21. Epub 2013 Apr 19 doi: 10.1038/modpathol.2013.56. PMID: 23599148
Primary temporal bone angiosarcoma: a case report.
Scholsem M, Raket D, Flandroy P, Sciot R, Deprez M
J Neurooncol 2005 Nov;75(2):121-5. doi: 10.1007/s11060-005-0375-0. PMID: 16132518

Diagnosis

A low-grade bone angiosarcoma presented as low to mild (18)F-FDG uptake mimicking multiple myeloma.
Li F, Ou X
Hell J Nucl Med 2020 Sep-Dec;23(3):360-361. Epub 2020 Dec 14 doi: 10.1967/s002449912217. PMID: 33306768
A Clinical Model of Bone Angiosarcoma Patients: A Population-based Analysis of Epidemiology, Prognosis, and Treatment.
Wang B, Chen LJ, Wang XY
Orthop Surg 2020 Dec;12(6):1652-1662. Epub 2020 Sep 10 doi: 10.1111/os.12803. PMID: 32914587Free PMC Article
Angiosarcoma of the Temporal Bone: Case Report and Review of the Literature.
Bernstock JD, Shafaat O, Hardigan A, Fox BM, Moore LS, Chagoya G, Elsayed G, Gessler F, Ilyas A, Yamashita D, McGrew B, Fisher WS 3rd, Hackney J, Sotoudeh H
World Neurosurg 2019 Oct;130:351-357. Epub 2019 Jul 19 doi: 10.1016/j.wneu.2019.07.107. PMID: 31330332
Active TGF-β signaling and decreased expression of PTEN separates angiosarcoma of bone from its soft tissue counterpart.
Verbeke SL, Bertoni F, Bacchini P, Oosting J, Sciot R, Krenács T, Bovée JV
Mod Pathol 2013 Sep;26(9):1211-21. Epub 2013 Apr 19 doi: 10.1038/modpathol.2013.56. PMID: 23599148
Primary temporal bone angiosarcoma: a case report.
Scholsem M, Raket D, Flandroy P, Sciot R, Deprez M
J Neurooncol 2005 Nov;75(2):121-5. doi: 10.1007/s11060-005-0375-0. PMID: 16132518

Therapy

Primary temporal bone angiosarcoma: a case report.
Scholsem M, Raket D, Flandroy P, Sciot R, Deprez M
J Neurooncol 2005 Nov;75(2):121-5. doi: 10.1007/s11060-005-0375-0. PMID: 16132518

Prognosis

A Clinical Model of Bone Angiosarcoma Patients: A Population-based Analysis of Epidemiology, Prognosis, and Treatment.
Wang B, Chen LJ, Wang XY
Orthop Surg 2020 Dec;12(6):1652-1662. Epub 2020 Sep 10 doi: 10.1111/os.12803. PMID: 32914587Free PMC Article
Active TGF-β signaling and decreased expression of PTEN separates angiosarcoma of bone from its soft tissue counterpart.
Verbeke SL, Bertoni F, Bacchini P, Oosting J, Sciot R, Krenács T, Bovée JV
Mod Pathol 2013 Sep;26(9):1211-21. Epub 2013 Apr 19 doi: 10.1038/modpathol.2013.56. PMID: 23599148
Primary bone angiosarcoma in a patient with Gaucher disease.
Zver S, Bracko M, Andoljsek D
Int J Hematol 2010 Sep;92(2):374-7. Epub 2010 Jul 27 doi: 10.1007/s12185-010-0643-4. PMID: 20661673
Primary temporal bone angiosarcoma: a case report.
Scholsem M, Raket D, Flandroy P, Sciot R, Deprez M
J Neurooncol 2005 Nov;75(2):121-5. doi: 10.1007/s11060-005-0375-0. PMID: 16132518

Clinical prediction guides

A Clinical Model of Bone Angiosarcoma Patients: A Population-based Analysis of Epidemiology, Prognosis, and Treatment.
Wang B, Chen LJ, Wang XY
Orthop Surg 2020 Dec;12(6):1652-1662. Epub 2020 Sep 10 doi: 10.1111/os.12803. PMID: 32914587Free PMC Article
Active TGF-β signaling and decreased expression of PTEN separates angiosarcoma of bone from its soft tissue counterpart.
Verbeke SL, Bertoni F, Bacchini P, Oosting J, Sciot R, Krenács T, Bovée JV
Mod Pathol 2013 Sep;26(9):1211-21. Epub 2013 Apr 19 doi: 10.1038/modpathol.2013.56. PMID: 23599148

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