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Microcystic meningioma

MedGen UID:
234616
•Concept ID:
C1384408
•
Neoplastic Process
Synonyms: Meningioma, Microcystic; Meningiomas, Microcystic; Microcystic Meningioma; Microcystic Meningiomas
SNOMED CT: Microcystic meningioma (253084001)
 
Monarch Initiative: MONDO:0003058

Definition

A WHO grade I meningioma characterized by the presence of intercellular microcystic spaces that contain mucinous fluid. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMicrocystic meningioma

Professional guidelines

PubMed

Paradigm Shift in the Treatment of Meningiomas.
Krischek B, Goldbrunner R
Adv Exp Med Biol 2023;1416:1-4. doi: 10.1007/978-3-031-29750-2_1. PMID: 37432615
Emerging systemic treatment options in meningioma.
Mair MJ, Berghoff AS, Brastianos PK, Preusser M
J Neurooncol 2023 Jan;161(2):245-258. Epub 2022 Oct 1 doi: 10.1007/s11060-022-04148-8. PMID: 36181606Free PMC Article
EANO guideline on the diagnosis and management of meningiomas.
Goldbrunner R, Stavrinou P, Jenkinson MD, Sahm F, Mawrin C, Weber DC, Preusser M, Minniti G, Lund-Johansen M, Lefranc F, Houdart E, Sallabanda K, Le Rhun E, Nieuwenhuizen D, Tabatabai G, Soffietti R, Weller M
Neuro Oncol 2021 Nov 2;23(11):1821-1834. doi: 10.1093/neuonc/noab150. PMID: 34181733Free PMC Article

Recent clinical studies

Etiology

Discrimination between microcystic meningioma and atypical meningioma using whole-lesion apparent diffusion coefficient histogram analysis.
Liu X, Huang X, Han T, Li S, Xue C, Deng J, Zhou Q, Sun Q, Zhou J
Clin Radiol 2022 Nov;77(11):864-869. Epub 2022 Aug 25 doi: 10.1016/j.crad.2022.07.004. PMID: 36030110
Comparative analysis of magnetic resonance imaging and pathological findings of microcystic meningioma and meningeal Ewing sarcoma/peripheral primitive neuroectodermal tumors.
Zhang J, Sun Q, Zhang G, Cao Y, Zhou J
Acta Neurol Belg 2021 Dec;121(6):1607-1613. Epub 2020 Jul 15 doi: 10.1007/s13760-020-01436-w. PMID: 32671692
Differentiating microcystic meningioma from atypical meningioma using diffusion-weighted imaging.
Xiaoai K, Qing Z, Lei H, Junlin Z
Neuroradiology 2020 May;62(5):601-607. Epub 2020 Jan 29 doi: 10.1007/s00234-020-02374-3. PMID: 31996968
Dual use of E-cadherin and D2-40 immunostaining in unusual meningioma subtypes.
Mrachek EK, Davis D, Kleinschmidt-DeMasters BK
Am J Clin Pathol 2015 Dec;144(6):923-34. doi: 10.1309/AJCPSULJ6DW5REHR. PMID: 26573000
Long-term follow-up of surgical resection of microcystic meningiomas.
Kalani MY, Cavallo C, Coons SW, Lettieri SC, Nakaji P, Porter RW, Spetzler RF, Feiz-Erfan I
J Clin Neurosci 2015 Apr;22(4):713-7. Epub 2015 Feb 9 doi: 10.1016/j.jocn.2014.12.004. PMID: 25677877

Diagnosis

Distinct clinical outcome of microcystic meningioma as a WHO grade 1 meningioma subtype.
Ren L, Hua L, Bao Z, Deng J, Wang D, Chen J, Chen H, Juratli TA, Wakimoto H, Gong Y
J Neurooncol 2023 Jan;161(2):193-202. Epub 2022 May 25 doi: 10.1007/s11060-022-04034-3. PMID: 35612696
Discrimination between microcystic meningioma and atypical meningioma using whole-lesion apparent diffusion coefficient histogram analysis.
Liu X, Huang X, Han T, Li S, Xue C, Deng J, Zhou Q, Sun Q, Zhou J
Clin Radiol 2022 Nov;77(11):864-869. Epub 2022 Aug 25 doi: 10.1016/j.crad.2022.07.004. PMID: 36030110
Comparative analysis of magnetic resonance imaging and pathological findings of microcystic meningioma and meningeal Ewing sarcoma/peripheral primitive neuroectodermal tumors.
Zhang J, Sun Q, Zhang G, Cao Y, Zhou J
Acta Neurol Belg 2021 Dec;121(6):1607-1613. Epub 2020 Jul 15 doi: 10.1007/s13760-020-01436-w. PMID: 32671692
Differentiating microcystic meningioma from atypical meningioma using diffusion-weighted imaging.
Xiaoai K, Qing Z, Lei H, Junlin Z
Neuroradiology 2020 May;62(5):601-607. Epub 2020 Jan 29 doi: 10.1007/s00234-020-02374-3. PMID: 31996968
Microcystic meningioma of the calvarium: a series of 9 cases and review of the literature.
Velázquez Vega JE, Rosenberg AE
Am J Surg Pathol 2015 Apr;39(4):505-11. doi: 10.1097/PAS.0000000000000347. PMID: 25517950

Therapy

Loss of SMARCE1 expression is a specific diagnostic marker of clear cell meningioma: a comprehensive immunophenotypical and molecular analysis.
Tauziede-Espariat A, Parfait B, Besnard A, Lacombe J, Pallud J, Tazi S, Puget S, Lot G, Terris B, Cohen J, Vidaud M, Figarella-Branger D, Monnien F, Polivka M, Adle-Biassette H, Varlet P
Brain Pathol 2018 Jul;28(4):466-474. Epub 2017 Jun 12 doi: 10.1111/bpa.12524. PMID: 28474749Free PMC Article
Microcystic meningioma: importance of obvious hypointensity on T1-weighted magnetic resonance images.
Chen CJ, Tseng YC, Hsu HL, Jung SM
J Comput Assist Tomogr 2008 Jan-Feb;32(1):130-4. doi: 10.1097/RCT.0b013e318064f127. PMID: 18303301
Microcystic meningioma: clinicopathological features of 6 cases.
Nishio S, Takeshita I, Morioka T, Fukui M
Neurol Res 1994 Aug;16(4):251-6. doi: 10.1080/01616412.1994.11740236. PMID: 7984255

Prognosis

Distinct clinical outcome of microcystic meningioma as a WHO grade 1 meningioma subtype.
Ren L, Hua L, Bao Z, Deng J, Wang D, Chen J, Chen H, Juratli TA, Wakimoto H, Gong Y
J Neurooncol 2023 Jan;161(2):193-202. Epub 2022 May 25 doi: 10.1007/s11060-022-04034-3. PMID: 35612696
Discrimination between microcystic meningioma and atypical meningioma using whole-lesion apparent diffusion coefficient histogram analysis.
Liu X, Huang X, Han T, Li S, Xue C, Deng J, Zhou Q, Sun Q, Zhou J
Clin Radiol 2022 Nov;77(11):864-869. Epub 2022 Aug 25 doi: 10.1016/j.crad.2022.07.004. PMID: 36030110
Differentiating microcystic meningioma from atypical meningioma using diffusion-weighted imaging.
Xiaoai K, Qing Z, Lei H, Junlin Z
Neuroradiology 2020 May;62(5):601-607. Epub 2020 Jan 29 doi: 10.1007/s00234-020-02374-3. PMID: 31996968
Long-term follow-up of surgical resection of microcystic meningiomas.
Kalani MY, Cavallo C, Coons SW, Lettieri SC, Nakaji P, Porter RW, Spetzler RF, Feiz-Erfan I
J Clin Neurosci 2015 Apr;22(4):713-7. Epub 2015 Feb 9 doi: 10.1016/j.jocn.2014.12.004. PMID: 25677877
Microcystic meningioma of the calvarium: a series of 9 cases and review of the literature.
Velázquez Vega JE, Rosenberg AE
Am J Surg Pathol 2015 Apr;39(4):505-11. doi: 10.1097/PAS.0000000000000347. PMID: 25517950

Clinical prediction guides

Discrimination between microcystic meningioma and atypical meningioma using whole-lesion apparent diffusion coefficient histogram analysis.
Liu X, Huang X, Han T, Li S, Xue C, Deng J, Zhou Q, Sun Q, Zhou J
Clin Radiol 2022 Nov;77(11):864-869. Epub 2022 Aug 25 doi: 10.1016/j.crad.2022.07.004. PMID: 36030110
Differentiating microcystic meningioma from atypical meningioma using diffusion-weighted imaging.
Xiaoai K, Qing Z, Lei H, Junlin Z
Neuroradiology 2020 May;62(5):601-607. Epub 2020 Jan 29 doi: 10.1007/s00234-020-02374-3. PMID: 31996968
Characteristic features and proposed classification in 69 cases of intracranial microcystic meningiomas.
Lin Z, Zhao M, Li X, Wang J, Qiu P, Lan F, Guan C, Liao D, Shen D, Lu J, Que S, Jiang Z
Neurosurg Rev 2019 Jun;42(2):443-453. Epub 2018 May 2 doi: 10.1007/s10143-018-0982-9. PMID: 29721630
Long-term follow-up of surgical resection of microcystic meningiomas.
Kalani MY, Cavallo C, Coons SW, Lettieri SC, Nakaji P, Porter RW, Spetzler RF, Feiz-Erfan I
J Clin Neurosci 2015 Apr;22(4):713-7. Epub 2015 Feb 9 doi: 10.1016/j.jocn.2014.12.004. PMID: 25677877
Microcystic meningioma of the calvarium: a series of 9 cases and review of the literature.
Velázquez Vega JE, Rosenberg AE
Am J Surg Pathol 2015 Apr;39(4):505-11. doi: 10.1097/PAS.0000000000000347. PMID: 25517950

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