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Central nervous system leiomyosarcoma

MedGen UID:
235254
Concept ID:
C1334385
Neoplastic Process
Synonyms: Central Nervous System Leiomyosarcoma; central nervous system leiomyosarcoma; CNS Leiomyosarcoma; CNS leiomyosarcoma; Leiomyosarcoma of Central Nervous System; leiomyosarcoma of central nervous system; Leiomyosarcoma of CNS; leiomyosarcoma of CNS; Leiomyosarcoma of the Central Nervous System; leiomyosarcoma of the central nervous system; Leiomyosarcoma of the CNS; leiomyosarcoma of the CNS
 
Monarch Initiative: MONDO:0003349

Definition

An aggressive malignant smooth muscle neoplasm, arising from the central nervous system. It is characterized by a proliferation of neoplastic spindle cells. [from NCI]

Professional guidelines

PubMed

Zhang GJ, Weng JC, Huo XL, Ma JP, Wang B, Wang L, Li H, Li D, Zhang JT, Wu Z
Neurosurg Rev 2021 Aug;44(4):2319-2328. Epub 2020 Oct 24 doi: 10.1007/s10143-020-01422-z. PMID: 33099713
Vickers MA, Wilkie GM, Robinson N, Rivera N, Haque T, Crawford DH, Barry J, Fraser N, Turner DM, Robertson V, Dyer P, Flanagan P, Newlands HR, Campbell J, Turner ML
Br J Haematol 2014 Nov;167(3):402-10. Epub 2014 Jul 26 doi: 10.1111/bjh.13051. PMID: 25066775Free PMC Article
Bindal RK, Sawaya RE, Leavens ME, Taylor SH, Guinee VF
Neurosurgery 1994 Aug;35(2):185-90; discussion 190-1. doi: 10.1227/00006123-199408000-00002. PMID: 7969824

Recent clinical studies

Therapy

Zhang J, Sun Y, Gao YJ, Zhou S
Transplant Proc 2020 Nov;52(9):2809-2812. Epub 2020 Jul 13 doi: 10.1016/j.transproceed.2020.06.023. PMID: 32674859
Abu Saadeh F, Riain CO, Cormack CM, Gleeson N
Ir J Med Sci 2019 May;188(2):619-624. Epub 2018 Aug 3 doi: 10.1007/s11845-018-1876-0. PMID: 30074141
Sanal O, Jing H, Ozgur T, Ayvaz D, Strauss-Albee DM, Ersoy-Evans S, Tezcan I, Turkkani G, Matthews HF, Haliloglu G, Yuce A, Yalcin B, Gokoz O, Oguz KK, Su HC
J Clin Immunol 2012 Aug;32(4):698-708. Epub 2012 Apr 4 doi: 10.1007/s10875-012-9664-5. PMID: 22476911Free PMC Article
Cioffi P, Laudadio L, Nuzzo A, Belfiglio M, Petrelli F, Grappasonni I
J Oncol Pharm Pract 2012 Jun;18(2):299-302. Epub 2011 Nov 7 doi: 10.1177/1078155211424628. PMID: 22065198
Aung L, Gorlick RG, Shi W, Thaler H, Shorter NA, Healey JH, Huvos AG, Meyers PA
Cancer 2002 Oct 15;95(8):1728-34. doi: 10.1002/cncr.10861. PMID: 12365021

Prognosis

Zhang GJ, Weng JC, Huo XL, Ma JP, Wang B, Wang L, Li H, Li D, Zhang JT, Wu Z
Neurosurg Rev 2021 Aug;44(4):2319-2328. Epub 2020 Oct 24 doi: 10.1007/s10143-020-01422-z. PMID: 33099713
Tonorezos ES, Friedman DN, Barnea D, Bosscha MI, Chantada G, Dommering CJ, de Graaf P, Dunkel IJ, Fabius AWM, Francis JH, Greer MC, Kleinerman RA, Kors WA, Laughlin S, Moll AC, Morton LM, Temming P, Tucker MA, van Leeuwen FE, Walsh MF, Oeffinger KC, Abramson DH
Ophthalmology 2020 Nov;127(11):1549-1557. Epub 2020 May 15 doi: 10.1016/j.ophtha.2020.05.024. PMID: 32422154Free PMC Article
Torihashi K, Chin M, Yoshida K, Narumi O, Yamagata S
World Neurosurg 2018 Aug;116:169-173. Epub 2018 May 16 doi: 10.1016/j.wneu.2018.05.004. PMID: 29753901
Bright CJ, Hawkins MM, Winter DL, Alessi D, Allodji RS, Bagnasco F, Bárdi E, Bautz A, Byrne J, Feijen EAM, Fidler MM, Garwicz S, Grabow D, Gudmundsdottir T, Guha J, Haddy N, Jankovic M, Kaatsch P, Kaiser M, Kuehni CE, Linge H, Øfstaas H, Ronckers CM, Skinner R, Teepen JC, Terenziani M, Vu-Bezin G, Wesenberg F, Wiebe T, Sacerdote C, Jakab Z, Haupt R, Lähteenmäki P, Zaletel LZ, Kuonen R, Winther JF, de Vathaire F, Kremer LC, Hjorth L, Reulen RC; PanCareSurFup Consortium
J Natl Cancer Inst 2018 Jun 1;110(6):649-660. doi: 10.1093/jnci/djx235. PMID: 29165710Free PMC Article
Zhang H, Dong L, Huang Y, Zhang B, Ma H, Zhou Y, Shu C, Cheng G
Onkologie 2012;35(10):609-16. Epub 2012 Sep 18 doi: 10.1159/000342676. PMID: 23038237

Clinical prediction guides

Kommoss FKF, Stichel D, Schrimpf D, Kriegsmann M, Tessier-Cloutier B, Talhouk A, McAlpine JN, Chang KTE, Sturm D, Pfister SM, Romero-Pérez L, Kirchner T, Grünewald TGP, Buslei R, Sinn HP, Mechtersheimer G, Schirmacher P, Schmidt D, Lehr HA, Sahm F, Huntsman DG, Gilks CB, Kommoss F, von Deimling A, Koelsche C
J Cancer Res Clin Oncol 2020 Jan;146(1):97-104. Epub 2019 Nov 25 doi: 10.1007/s00432-019-03093-w. PMID: 31768620
Saito A, Ninomiya A, Ishida T, Inoue T, Inoue T, Suzuki S, Ezura M, Uenohara H
World Neurosurg 2019 Feb;122:116-122. Epub 2018 Nov 1 doi: 10.1016/j.wneu.2018.10.132. PMID: 30391601
Romero-Rojas AE, Diaz-Perez JA, Ariza-Serrano LM, Amaro D, Lozano-Castillo A
Neuroradiol J 2013 Dec;26(6):639-48. Epub 2013 Dec 18 doi: 10.1177/197140091302600606. PMID: 24355182Free PMC Article
Li S, Itoh M, Ohta K, Ueda M, Mizuno A, Ohta E, Hida Y, Wang MX, Takeuchi K, Nakagawa T
Neurosci Lett 2011 Oct 10;503(3):208-14. Epub 2011 Aug 26 doi: 10.1016/j.neulet.2011.08.037. PMID: 21893162
Yorulmaz G, Erdogan G, Pestereli HE, Savas B, Karaveli FS
Wien Klin Wochenschr 2007;119(17-18):557-60. doi: 10.1007/s00508-007-0822-3. PMID: 17943409

Recent systematic reviews

Eatz T, Levy A, Merenzon M, Bystrom L, Berry K, Morell A, Bhatia S, Daggubati L, Higgins D, Schlumbrecht M, Komotar RJ, Shah AH, Ivan ME
World Neurosurg 2023 May;173:e91-e108. Epub 2023 Feb 11 doi: 10.1016/j.wneu.2023.02.007. PMID: 36775238

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